JP2009516501A - 鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング - Google Patents

鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング Download PDF

Info

Publication number
JP2009516501A
JP2009516501A JP2008532468A JP2008532468A JP2009516501A JP 2009516501 A JP2009516501 A JP 2009516501A JP 2008532468 A JP2008532468 A JP 2008532468A JP 2008532468 A JP2008532468 A JP 2008532468A JP 2009516501 A JP2009516501 A JP 2009516501A
Authority
JP
Japan
Prior art keywords
genes
risk
patients
gene
npc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008532468A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009516501A5 (enExample
Inventor
カオ,クオジャン
フアン,アンドリュー
Original Assignee
チャイナ シンセティック ラバー コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by チャイナ シンセティック ラバー コーポレーション filed Critical チャイナ シンセティック ラバー コーポレーション
Publication of JP2009516501A publication Critical patent/JP2009516501A/ja
Publication of JP2009516501A5 publication Critical patent/JP2009516501A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00Subject matter not provided for in other groups of this subclass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Data Mining & Analysis (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Bioethics (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Public Health (AREA)
  • Artificial Intelligence (AREA)
  • Epidemiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Signal Processing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2008532468A 2005-09-22 2006-09-22 鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング Pending JP2009516501A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71917105P 2005-09-22 2005-09-22
US72112905P 2005-09-28 2005-09-28
PCT/US2006/037203 WO2007038402A1 (en) 2005-09-22 2006-09-22 Gene expression profiling for identification of prognostic subclasses in nasopharyngeal carcinomas

Publications (2)

Publication Number Publication Date
JP2009516501A true JP2009516501A (ja) 2009-04-23
JP2009516501A5 JP2009516501A5 (enExample) 2011-01-06

Family

ID=37596251

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008532468A Pending JP2009516501A (ja) 2005-09-22 2006-09-22 鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング

Country Status (13)

Country Link
US (1) US7998674B2 (enExample)
EP (1) EP1934862A1 (enExample)
JP (1) JP2009516501A (enExample)
KR (1) KR20080063343A (enExample)
CN (2) CN102346816B (enExample)
AU (1) AU2006294880A1 (enExample)
BR (1) BRPI0616139A2 (enExample)
CA (1) CA2623403A1 (enExample)
IL (1) IL190253A0 (enExample)
NO (1) NO20081925L (enExample)
RU (1) RU2008115113A (enExample)
TW (1) TW200729050A (enExample)
WO (1) WO2007038402A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058018A2 (en) 2006-11-02 2008-05-15 Mayo Foundation For Medical Education And Research Predicting cancer outcome
US20090226912A1 (en) * 2007-12-21 2009-09-10 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
US9684001B2 (en) 2008-02-07 2017-06-20 Ranju Ralhan Biomarkers for head-and-neck cancers and precancers
CA2618163A1 (en) 2008-02-07 2009-08-07 K. W. Michael Siu Head and neck cancer biomarkers
EP2806054A1 (en) 2008-05-28 2014-11-26 Genomedx Biosciences Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10407731B2 (en) 2008-05-30 2019-09-10 Mayo Foundation For Medical Education And Research Biomarker panels for predicting prostate cancer outcomes
WO2010030167A2 (en) * 2008-09-12 2010-03-18 Cancer Research Initiative Foundation Method of detection and diagnosis of oral and nasopharyngeal cancers
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US9495515B1 (en) * 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
GB2512153B (en) * 2008-11-17 2014-11-12 Veracyte Inc Methods and compositions of molecular profiling for disease diagnostics
US9074258B2 (en) 2009-03-04 2015-07-07 Genomedx Biosciences Inc. Compositions and methods for classifying thyroid nodule disease
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
WO2011116380A2 (en) 2010-03-19 2011-09-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Hybrid model for the classification of carcinoma subtypes
US9732389B2 (en) 2010-09-03 2017-08-15 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with prostate cancer risk
US20130267443A1 (en) 2010-11-19 2013-10-10 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
US9534256B2 (en) 2011-01-06 2017-01-03 Wake Forest University Health Sciences Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer
WO2013090620A1 (en) 2011-12-13 2013-06-20 Genomedx Biosciences, Inc. Cancer diagnostics using non-coding transcripts
CN102732484B (zh) * 2012-07-10 2015-04-22 广东医学院 一种人鼻咽癌肿瘤干细胞系建立方法
ES2945036T3 (es) 2012-08-16 2023-06-28 Veracyte Sd Inc Pronóstico del cáncer de próstata mediante biomarcadores
CN103020454A (zh) * 2012-12-15 2013-04-03 中国科学院深圳先进技术研究院 发病关键因素提取与疾病预警方法及系统
KR101711584B1 (ko) * 2012-12-18 2017-03-02 재단법인 의약바이오컨버젼스연구단 변형된 eprs 단백질의 결정 구조 및 이의 결정화 방법
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
EP3770274A1 (en) 2014-11-05 2021-01-27 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
AU2018210695B2 (en) 2017-01-20 2024-07-18 The University Of British Columbia Molecular subtyping, prognosis, and treatment of bladder cancer
US11873532B2 (en) 2017-03-09 2024-01-16 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
WO2018205035A1 (en) 2017-05-12 2018-11-15 Genomedx Biosciences, Inc Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
CN109801680B (zh) * 2018-12-03 2023-02-28 广州中医药大学(广州中医药研究院) 基于tcga数据库的肿瘤转移复发预测方法及系统
CN111382217B (zh) * 2018-12-29 2025-06-24 北京奇虎科技有限公司 一种目的地推荐方法和装置
CN120473159B (zh) * 2025-07-14 2025-09-26 泛肽生物科技(浙江)有限公司 一种鼻咽癌远处转移预测模型的构建方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005525124A (ja) * 2002-05-14 2005-08-25 ザ チャイニーズ ユニバーシティ オブ ホンコン 核酸の検出及び分画により病態を評価する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1353947A2 (en) 2000-12-08 2003-10-22 Ipsogen Gene expression profiling of primary breast carcinomas using arrays of candidate genes
WO2002101560A1 (en) * 2001-06-12 2002-12-19 Cross Media Marketing Corp. System and method for traffic management
GB0201498D0 (en) * 2002-01-23 2002-03-13 Biotech Res Ventures Pte Ltd Materials and methods for treating cancer
CN1482256A (zh) * 2002-09-13 2004-03-17 中南大学 鼻咽癌分子标志物—brd7试剂盒
CN1445546A (zh) * 2003-01-08 2003-10-01 中山大学肿瘤防治中心 鼻咽癌早期诊断试剂盒

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005525124A (ja) * 2002-05-14 2005-08-25 ザ チャイニーズ ユニバーシティ オブ ホンコン 核酸の検出及び分画により病態を評価する方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
JPN6012007226; Acta biochimica et biophysica Sinica. 2005 Aug, Vol.37, No.8, p.541-546 *
JPN6012007227; Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005 Feb, Vol.30, No.1, p.1-6 *
JPN6012007228; Chinese journal of cancer. 2005 Feb, Vol.24, No.2, p.135-140 *
JPN6012007230; IEEE/ACM transactions on computational biology and bioinformatics. 2005 Apr-Jun, Vol.2, No.2, p.166- *
JPN6012007231; The Journal of molecular diagnostics. 2005 Aug, Vol.7, No.3, p.357-367 *

Also Published As

Publication number Publication date
WO2007038402A1 (en) 2007-04-05
CN101313306B (zh) 2011-11-16
RU2008115113A (ru) 2009-10-27
TW200729050A (en) 2007-08-01
EP1934862A1 (en) 2008-06-25
BRPI0616139A2 (pt) 2011-06-07
US20080281568A1 (en) 2008-11-13
IL190253A0 (en) 2008-11-03
CA2623403A1 (en) 2007-04-05
NO20081925L (no) 2008-06-20
CN102346816B (zh) 2014-12-03
KR20080063343A (ko) 2008-07-03
US7998674B2 (en) 2011-08-16
CN102346816A (zh) 2012-02-08
AU2006294880A1 (en) 2007-04-05
CN101313306A (zh) 2008-11-26
WO2007038402A9 (en) 2007-07-05

Similar Documents

Publication Publication Date Title
JP2009516501A (ja) 鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング
Luthra et al. Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation
JP4938672B2 (ja) p53の状態と遺伝子発現プロファイルとの関連性に基づき、癌を分類し、予後を予測し、そして診断する方法、システム、およびアレイ
JP2020031642A (ja) 遺伝子発現を用いた前立腺癌の予後を定量化する方法
CN102971435B (zh) 用于内分泌治疗下的乳腺癌复发预测的方法
JP6404304B2 (ja) メラノーマ癌の予後予測
KR20140105836A (ko) 다유전자 바이오마커의 확인
CN111961726A (zh) 使用靶基因表达的线性组合评价细胞信号传导途径活性
JP2011500071A (ja) 遺伝子に基づくアルゴリズム的ガン予後及び患者の臨床結果
AU2008203227B2 (en) Colorectal cancer prognostics
KR20110018930A (ko) 암 치료에서 예후적 및 예견적 마커의 확인 및 용도
EP2419540B1 (en) Methods and gene expression signature for assessing ras pathway activity
US20150247203A1 (en) Composition for detecting the response of rectal adenocarcinomas to radiochemotherapy
EP3144395A1 (en) Microrna signature as an indicator of the risk of early recurrence in patients with breast cancer
CA2475769C (en) Colorectal cancer prognostics
CN111315897B (zh) 用于黑素瘤检测的方法
US20050181377A1 (en) Targeted cancer therapy

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090921

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100518

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120221

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120520

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120530

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120620

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120627

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20121002