RU2008115113A - Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки - Google Patents
Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки Download PDFInfo
- Publication number
- RU2008115113A RU2008115113A RU2008115113/14A RU2008115113A RU2008115113A RU 2008115113 A RU2008115113 A RU 2008115113A RU 2008115113/14 A RU2008115113/14 A RU 2008115113/14A RU 2008115113 A RU2008115113 A RU 2008115113A RU 2008115113 A RU2008115113 A RU 2008115113A
- Authority
- RU
- Russia
- Prior art keywords
- risk
- genes listed
- expression
- genes
- distant metastasis
- Prior art date
Links
- 201000009030 Carcinoma Diseases 0.000 title 1
- 238000011223 gene expression profiling Methods 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 32
- 108090000623 proteins and genes Proteins 0.000 claims abstract 28
- 206010027476 Metastases Diseases 0.000 claims abstract 14
- 230000009401 metastasis Effects 0.000 claims abstract 14
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 claims abstract 5
- 206010061306 Nasopharyngeal cancer Diseases 0.000 claims abstract 5
- 108091008053 gene clusters Proteins 0.000 claims abstract 5
- 201000011216 nasopharynx carcinoma Diseases 0.000 claims abstract 5
- 101150106774 9 gene Proteins 0.000 claims abstract 2
- 238000007477 logistic regression Methods 0.000 claims abstract 2
- 239000000523 sample Substances 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Data Mining & Analysis (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Computation (AREA)
- Software Systems (AREA)
- Public Health (AREA)
- Artificial Intelligence (AREA)
- Bioethics (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71917105P | 2005-09-22 | 2005-09-22 | |
| US60/719,171 | 2005-09-22 | ||
| US72112905P | 2005-09-28 | 2005-09-28 | |
| US60/721,129 | 2005-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008115113A true RU2008115113A (ru) | 2009-10-27 |
Family
ID=37596251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008115113/14A RU2008115113A (ru) | 2005-09-22 | 2006-09-22 | Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7998674B2 (enExample) |
| EP (1) | EP1934862A1 (enExample) |
| JP (1) | JP2009516501A (enExample) |
| KR (1) | KR20080063343A (enExample) |
| CN (2) | CN101313306B (enExample) |
| AU (1) | AU2006294880A1 (enExample) |
| BR (1) | BRPI0616139A2 (enExample) |
| CA (1) | CA2623403A1 (enExample) |
| IL (1) | IL190253A0 (enExample) |
| NO (1) | NO20081925L (enExample) |
| RU (1) | RU2008115113A (enExample) |
| TW (1) | TW200729050A (enExample) |
| WO (1) | WO2007038402A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8338109B2 (en) | 2006-11-02 | 2012-12-25 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| US20090226912A1 (en) * | 2007-12-21 | 2009-09-10 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| CA2618163A1 (en) | 2008-02-07 | 2009-08-07 | K. W. Michael Siu | Head and neck cancer biomarkers |
| US9684001B2 (en) | 2008-02-07 | 2017-06-20 | Ranju Ralhan | Biomarkers for head-and-neck cancers and precancers |
| CA2725978A1 (en) | 2008-05-28 | 2009-12-03 | Genomedx Biosciences, Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| EP2334826A4 (en) * | 2008-09-12 | 2012-01-25 | Cancer Res Initiative Foundation | PROCEDURE FOR THE DETECTION AND DIAGNOSIS OF ORAL AND NASOPHARYNGEAL TUMORS |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| GB2512153B (en) * | 2008-11-17 | 2014-11-12 | Veracyte Inc | Methods and compositions of molecular profiling for disease diagnostics |
| US9074258B2 (en) | 2009-03-04 | 2015-07-07 | Genomedx Biosciences Inc. | Compositions and methods for classifying thyroid nodule disease |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| US10446272B2 (en) | 2009-12-09 | 2019-10-15 | Veracyte, Inc. | Methods and compositions for classification of samples |
| WO2011116380A2 (en) * | 2010-03-19 | 2011-09-22 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Hybrid model for the classification of carcinoma subtypes |
| US9732389B2 (en) | 2010-09-03 | 2017-08-15 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| US9534256B2 (en) | 2011-01-06 | 2017-01-03 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer |
| US10513737B2 (en) | 2011-12-13 | 2019-12-24 | Decipher Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| CN102732484B (zh) * | 2012-07-10 | 2015-04-22 | 广东医学院 | 一种人鼻咽癌肿瘤干细胞系建立方法 |
| ES3015226T3 (en) | 2012-08-16 | 2025-04-30 | Veracyte Sd Inc | Prostate cancer prognosis using biomarkers |
| CN103020454A (zh) * | 2012-12-15 | 2013-04-03 | 中国科学院深圳先进技术研究院 | 发病关键因素提取与疾病预警方法及系统 |
| KR101711584B1 (ko) * | 2012-12-18 | 2017-03-02 | 재단법인 의약바이오컨버젼스연구단 | 변형된 eprs 단백질의 결정 구조 및 이의 결정화 방법 |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| CN114606309A (zh) | 2014-11-05 | 2022-06-10 | 威拉赛特公司 | 使用机器学习和高维转录数据的诊断系统和方法 |
| US11414708B2 (en) | 2016-08-24 | 2022-08-16 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| AU2018210695B2 (en) | 2017-01-20 | 2024-07-18 | The University Of British Columbia | Molecular subtyping, prognosis, and treatment of bladder cancer |
| WO2018165600A1 (en) | 2017-03-09 | 2018-09-13 | Genomedx Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| US11078542B2 (en) | 2017-05-12 | 2021-08-03 | Decipher Biosciences, Inc. | Genetic signatures to predict prostate cancer metastasis and identify tumor aggressiveness |
| US11217329B1 (en) | 2017-06-23 | 2022-01-04 | Veracyte, Inc. | Methods and systems for determining biological sample integrity |
| AU2018310987A1 (en) | 2017-08-04 | 2020-02-27 | Decipher Biosciences, Inc. | Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy |
| CN109801680B (zh) * | 2018-12-03 | 2023-02-28 | 广州中医药大学(广州中医药研究院) | 基于tcga数据库的肿瘤转移复发预测方法及系统 |
| CN111382217B (zh) * | 2018-12-29 | 2025-06-24 | 北京奇虎科技有限公司 | 一种目的地推荐方法和装置 |
| CN120473159B (zh) * | 2025-07-14 | 2025-09-26 | 泛肽生物科技(浙江)有限公司 | 一种鼻咽癌远处转移预测模型的构建方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004537261A (ja) | 2000-12-08 | 2004-12-16 | イプソゲン | 候補遺伝子のアレイを用いた原発性乳がんの遺伝子発現プロファイリング |
| US20030014539A1 (en) * | 2001-06-12 | 2003-01-16 | Reznick Josh L. | System and method for traffic management |
| GB0201498D0 (en) * | 2002-01-23 | 2002-03-13 | Biotech Res Ventures Pte Ltd | Materials and methods for treating cancer |
| US20040009518A1 (en) * | 2002-05-14 | 2004-01-15 | The Chinese University Of Hong Kong | Methods for evaluating a disease condition by nucleic acid detection and fractionation |
| CN1482256A (zh) * | 2002-09-13 | 2004-03-17 | 中南大学 | 鼻咽癌分子标志物—brd7试剂盒 |
| CN1445546A (zh) * | 2003-01-08 | 2003-10-01 | 中山大学肿瘤防治中心 | 鼻咽癌早期诊断试剂盒 |
-
2006
- 2006-09-22 JP JP2008532468A patent/JP2009516501A/ja active Pending
- 2006-09-22 TW TW095135134A patent/TW200729050A/zh unknown
- 2006-09-22 AU AU2006294880A patent/AU2006294880A1/en not_active Abandoned
- 2006-09-22 CN CN2006800437623A patent/CN101313306B/zh active Active
- 2006-09-22 WO PCT/US2006/037203 patent/WO2007038402A1/en not_active Ceased
- 2006-09-22 KR KR1020087009513A patent/KR20080063343A/ko not_active Ceased
- 2006-09-22 CN CN201110276634.6A patent/CN102346816B/zh active Active
- 2006-09-22 BR BRPI0616139-1A patent/BRPI0616139A2/pt not_active IP Right Cessation
- 2006-09-22 EP EP06804095A patent/EP1934862A1/en not_active Withdrawn
- 2006-09-22 CA CA002623403A patent/CA2623403A1/en not_active Abandoned
- 2006-09-22 US US12/067,549 patent/US7998674B2/en active Active
- 2006-09-22 RU RU2008115113/14A patent/RU2008115113A/ru unknown
-
2008
- 2008-03-18 IL IL190253A patent/IL190253A0/en unknown
- 2008-04-22 NO NO20081925A patent/NO20081925L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007038402A9 (en) | 2007-07-05 |
| IL190253A0 (en) | 2008-11-03 |
| NO20081925L (no) | 2008-06-20 |
| BRPI0616139A2 (pt) | 2011-06-07 |
| WO2007038402A1 (en) | 2007-04-05 |
| CN101313306B (zh) | 2011-11-16 |
| KR20080063343A (ko) | 2008-07-03 |
| CN101313306A (zh) | 2008-11-26 |
| US20080281568A1 (en) | 2008-11-13 |
| CN102346816A (zh) | 2012-02-08 |
| US7998674B2 (en) | 2011-08-16 |
| JP2009516501A (ja) | 2009-04-23 |
| EP1934862A1 (en) | 2008-06-25 |
| TW200729050A (en) | 2007-08-01 |
| CA2623403A1 (en) | 2007-04-05 |
| CN102346816B (zh) | 2014-12-03 |
| AU2006294880A1 (en) | 2007-04-05 |
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