RU2008115113A - Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки - Google Patents
Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки Download PDFInfo
- Publication number
- RU2008115113A RU2008115113A RU2008115113/14A RU2008115113A RU2008115113A RU 2008115113 A RU2008115113 A RU 2008115113A RU 2008115113/14 A RU2008115113/14 A RU 2008115113/14A RU 2008115113 A RU2008115113 A RU 2008115113A RU 2008115113 A RU2008115113 A RU 2008115113A
- Authority
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- Russia
- Prior art keywords
- risk
- genes listed
- expression
- genes
- distant metastasis
- Prior art date
Links
- 201000009030 Carcinoma Diseases 0.000 title 1
- 238000011223 gene expression profiling Methods 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 32
- 108090000623 proteins and genes Proteins 0.000 claims abstract 28
- 206010027476 Metastases Diseases 0.000 claims abstract 14
- 230000009401 metastasis Effects 0.000 claims abstract 14
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 claims abstract 5
- 206010061306 Nasopharyngeal cancer Diseases 0.000 claims abstract 5
- 108091008053 gene clusters Proteins 0.000 claims abstract 5
- 201000011216 nasopharynx carcinoma Diseases 0.000 claims abstract 5
- 101150106774 9 gene Proteins 0.000 claims abstract 2
- 238000007477 logistic regression Methods 0.000 claims abstract 2
- 239000000523 sample Substances 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Data Mining & Analysis (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Bioethics (AREA)
- Evolutionary Computation (AREA)
- Software Systems (AREA)
- Public Health (AREA)
- Artificial Intelligence (AREA)
- Epidemiology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Databases & Information Systems (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Signal Processing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71917105P | 2005-09-22 | 2005-09-22 | |
| US60/719,171 | 2005-09-22 | ||
| US72112905P | 2005-09-28 | 2005-09-28 | |
| US60/721,129 | 2005-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008115113A true RU2008115113A (ru) | 2009-10-27 |
Family
ID=37596251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008115113/14A RU2008115113A (ru) | 2005-09-22 | 2006-09-22 | Профилирование генной экспрессии для идентификации прогностических субклассов при карциноме носоглотки |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7998674B2 (enExample) |
| EP (1) | EP1934862A1 (enExample) |
| JP (1) | JP2009516501A (enExample) |
| KR (1) | KR20080063343A (enExample) |
| CN (2) | CN102346816B (enExample) |
| AU (1) | AU2006294880A1 (enExample) |
| BR (1) | BRPI0616139A2 (enExample) |
| CA (1) | CA2623403A1 (enExample) |
| IL (1) | IL190253A0 (enExample) |
| NO (1) | NO20081925L (enExample) |
| RU (1) | RU2008115113A (enExample) |
| TW (1) | TW200729050A (enExample) |
| WO (1) | WO2007038402A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008058018A2 (en) | 2006-11-02 | 2008-05-15 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| US20090226912A1 (en) * | 2007-12-21 | 2009-09-10 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US9684001B2 (en) | 2008-02-07 | 2017-06-20 | Ranju Ralhan | Biomarkers for head-and-neck cancers and precancers |
| CA2618163A1 (en) | 2008-02-07 | 2009-08-07 | K. W. Michael Siu | Head and neck cancer biomarkers |
| EP2806054A1 (en) | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| WO2010030167A2 (en) * | 2008-09-12 | 2010-03-18 | Cancer Research Initiative Foundation | Method of detection and diagnosis of oral and nasopharyngeal cancers |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9495515B1 (en) * | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| GB2512153B (en) * | 2008-11-17 | 2014-11-12 | Veracyte Inc | Methods and compositions of molecular profiling for disease diagnostics |
| US9074258B2 (en) | 2009-03-04 | 2015-07-07 | Genomedx Biosciences Inc. | Compositions and methods for classifying thyroid nodule disease |
| JP6078339B2 (ja) | 2009-05-07 | 2017-02-08 | ベラサイト インコーポレイテッド | 甲状腺状態の診断のための方法および組成物 |
| US10446272B2 (en) | 2009-12-09 | 2019-10-15 | Veracyte, Inc. | Methods and compositions for classification of samples |
| WO2011116380A2 (en) | 2010-03-19 | 2011-09-22 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Hybrid model for the classification of carcinoma subtypes |
| US9732389B2 (en) | 2010-09-03 | 2017-08-15 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| US9534256B2 (en) | 2011-01-06 | 2017-01-03 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer |
| WO2013090620A1 (en) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| CN102732484B (zh) * | 2012-07-10 | 2015-04-22 | 广东医学院 | 一种人鼻咽癌肿瘤干细胞系建立方法 |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| CN103020454A (zh) * | 2012-12-15 | 2013-04-03 | 中国科学院深圳先进技术研究院 | 发病关键因素提取与疾病预警方法及系统 |
| KR101711584B1 (ko) * | 2012-12-18 | 2017-03-02 | 재단법인 의약바이오컨버젼스연구단 | 변형된 eprs 단백질의 결정 구조 및 이의 결정화 방법 |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3770274A1 (en) | 2014-11-05 | 2021-01-27 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| US11414708B2 (en) | 2016-08-24 | 2022-08-16 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| AU2018210695B2 (en) | 2017-01-20 | 2024-07-18 | The University Of British Columbia | Molecular subtyping, prognosis, and treatment of bladder cancer |
| US11873532B2 (en) | 2017-03-09 | 2024-01-16 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| WO2018205035A1 (en) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| US11217329B1 (en) | 2017-06-23 | 2022-01-04 | Veracyte, Inc. | Methods and systems for determining biological sample integrity |
| CN109801680B (zh) * | 2018-12-03 | 2023-02-28 | 广州中医药大学(广州中医药研究院) | 基于tcga数据库的肿瘤转移复发预测方法及系统 |
| CN111382217B (zh) * | 2018-12-29 | 2025-06-24 | 北京奇虎科技有限公司 | 一种目的地推荐方法和装置 |
| CN120473159B (zh) * | 2025-07-14 | 2025-09-26 | 泛肽生物科技(浙江)有限公司 | 一种鼻咽癌远处转移预测模型的构建方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1353947A2 (en) | 2000-12-08 | 2003-10-22 | Ipsogen | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
| WO2002101560A1 (en) * | 2001-06-12 | 2002-12-19 | Cross Media Marketing Corp. | System and method for traffic management |
| GB0201498D0 (en) * | 2002-01-23 | 2002-03-13 | Biotech Res Ventures Pte Ltd | Materials and methods for treating cancer |
| US20040009518A1 (en) * | 2002-05-14 | 2004-01-15 | The Chinese University Of Hong Kong | Methods for evaluating a disease condition by nucleic acid detection and fractionation |
| CN1482256A (zh) * | 2002-09-13 | 2004-03-17 | 中南大学 | 鼻咽癌分子标志物—brd7试剂盒 |
| CN1445546A (zh) * | 2003-01-08 | 2003-10-01 | 中山大学肿瘤防治中心 | 鼻咽癌早期诊断试剂盒 |
-
2006
- 2006-09-22 JP JP2008532468A patent/JP2009516501A/ja active Pending
- 2006-09-22 BR BRPI0616139-1A patent/BRPI0616139A2/pt not_active IP Right Cessation
- 2006-09-22 CA CA002623403A patent/CA2623403A1/en not_active Abandoned
- 2006-09-22 US US12/067,549 patent/US7998674B2/en active Active
- 2006-09-22 CN CN201110276634.6A patent/CN102346816B/zh active Active
- 2006-09-22 RU RU2008115113/14A patent/RU2008115113A/ru unknown
- 2006-09-22 KR KR1020087009513A patent/KR20080063343A/ko not_active Ceased
- 2006-09-22 WO PCT/US2006/037203 patent/WO2007038402A1/en not_active Ceased
- 2006-09-22 AU AU2006294880A patent/AU2006294880A1/en not_active Abandoned
- 2006-09-22 EP EP06804095A patent/EP1934862A1/en not_active Withdrawn
- 2006-09-22 CN CN2006800437623A patent/CN101313306B/zh active Active
- 2006-09-22 TW TW095135134A patent/TW200729050A/zh unknown
-
2008
- 2008-03-18 IL IL190253A patent/IL190253A0/en unknown
- 2008-04-22 NO NO20081925A patent/NO20081925L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007038402A1 (en) | 2007-04-05 |
| CN101313306B (zh) | 2011-11-16 |
| TW200729050A (en) | 2007-08-01 |
| EP1934862A1 (en) | 2008-06-25 |
| BRPI0616139A2 (pt) | 2011-06-07 |
| US20080281568A1 (en) | 2008-11-13 |
| IL190253A0 (en) | 2008-11-03 |
| CA2623403A1 (en) | 2007-04-05 |
| NO20081925L (no) | 2008-06-20 |
| CN102346816B (zh) | 2014-12-03 |
| KR20080063343A (ko) | 2008-07-03 |
| US7998674B2 (en) | 2011-08-16 |
| CN102346816A (zh) | 2012-02-08 |
| AU2006294880A1 (en) | 2007-04-05 |
| JP2009516501A (ja) | 2009-04-23 |
| CN101313306A (zh) | 2008-11-26 |
| WO2007038402A9 (en) | 2007-07-05 |
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