JP2009514553A - 修飾アネキシンタンパク質および臓器移植における該タンパク質の使用法 - Google Patents
修飾アネキシンタンパク質および臓器移植における該タンパク質の使用法 Download PDFInfo
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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| PCT/US2006/060227 WO2007073509A2 (en) | 2005-11-03 | 2006-10-25 | Modified annexin proteins and methods for their use in organ transplantation |
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| US20090291086A1 (en) * | 2001-02-21 | 2009-11-26 | Alavita Pharmaceuticals, Inc. | Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia |
| US7645739B2 (en) * | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
| JP4191189B2 (ja) * | 2005-12-08 | 2008-12-03 | 康生 梅津 | がん関連遺伝子活性化能を有するペプチド |
| WO2007149567A2 (en) | 2006-06-21 | 2007-12-27 | Musc Foundation For Research Development | Targeting complement factor h for treatment of diseases |
| CA2708956C (en) * | 2007-12-18 | 2018-07-17 | Athera Biotechnologies Ab | Use of annexin a5 for the treatment of vascular disease |
| ES2530228T3 (es) * | 2008-08-26 | 2015-02-27 | Mosamedix B.V. | Anexinas radiomarcadas |
| WO2010034015A2 (en) | 2008-09-22 | 2010-03-25 | The Regents Of The University Of Colorado, A Body Corporate | Modulating the alternative complement pathway |
| JP5871798B2 (ja) | 2009-07-02 | 2016-03-01 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | 肝再生を刺激する方法 |
| MX2012005151A (es) | 2009-11-05 | 2012-08-23 | Federico Ii University Of Naples | Tratamiento de hemoglobinuria nocturna paroxismica, anemias hemoliticas y estados de enfermedad que involucran hemolisis intravascular y extravascular. |
| WO2011069090A1 (en) * | 2009-12-04 | 2011-06-09 | Alavita Pharmaceuticals, Inc. | Inhibition of the activation of coagulation factor xii by ligands of phosphatidylserine |
| WO2011143637A1 (en) | 2010-05-14 | 2011-11-17 | The Regents Of The University Of Colorado, A Body Corporate | Improved complement receptor 2 (cr2) targeting groups |
| US9815890B2 (en) | 2010-06-22 | 2017-11-14 | The Regents Of The University Of Colorado, A Body Corporate | Antibodies to the C3d fragment of complement component 3 |
| US20140037614A1 (en) * | 2011-04-05 | 2014-02-06 | Knut Pettersson | Therapeutic and prophylactic methods, uses and compositions comprising anexin a5 |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| AU2013302441B2 (en) | 2012-08-17 | 2018-05-10 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for detecting complement activation |
| US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
| US9361735B1 (en) | 2014-07-11 | 2016-06-07 | State Farm Mutual Automobile Insurance Company | Method and system of using spatial sensors on vehicle frame to determine crash information |
| GB2583560A (en) | 2018-12-11 | 2020-11-04 | Admirx Inc | Fusion protein constructs for complement associated disease |
| EP4313020A4 (en) * | 2021-03-26 | 2025-01-29 | Emory University | MANAGING THE ACUTE AND LONG-TERM EFFECTS OF CORONAVIRUS INFECTIONS AND RELATED COMPOUNDS |
Citations (3)
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| WO1999019470A2 (en) * | 1997-10-09 | 1999-04-22 | The Regents Of The University Of California | Gfp-annexin fusion proteins |
| WO2003021229A2 (en) * | 2001-09-05 | 2003-03-13 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| WO2005086955A2 (en) * | 2004-03-11 | 2005-09-22 | Alavita Pharmaceuticals, Inc | Modified annexin proteins and methods for preventing thrombosis |
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| US4002531A (en) * | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| DE3315000A1 (de) * | 1983-04-26 | 1984-10-31 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)4(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
| US5066788A (en) * | 1984-09-21 | 1991-11-19 | Boehringer Ingelheim International Gmbh | Blood coagulation inhibiting proteins, processes for preparing them and their uses |
| KR930007434B1 (ko) * | 1984-09-21 | 1993-08-10 | 베링거 잉겔하임 인터내셔날 게엠베하 | 혈액응고 억제 단백질 제조방법 |
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| CA1265446A (en) * | 1985-09-30 | 1990-02-06 | Masahiro Maki | Anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component |
| JPH08840B2 (ja) * | 1986-11-14 | 1996-01-10 | 興和株式会社 | 抗pciモノクローナル抗体、これを用いた抗pciの精製法及び免疫学的測定法 |
| DE3643182A1 (de) * | 1986-12-18 | 1988-06-30 | Behringwerke Ag | Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4 |
| US4937324A (en) * | 1987-02-06 | 1990-06-26 | Zymogenetics, Inc. | Chromatographic purification of human proteins having anticoagulant and anti-inflammatory activity |
| JP2660514B2 (ja) * | 1987-02-20 | 1997-10-08 | 興和株式会社 | 抗血液凝固作用を有するポリペプチド |
| PT87083B (pt) | 1987-03-28 | 1992-07-31 | Boehringer Ingelheim Int | Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem |
| US4965251A (en) * | 1987-04-03 | 1990-10-23 | The Board Of Regents Of The University Of Washington | Pulse treatment of hemoglobinopathies with erythropoietin |
| DE3737239A1 (de) | 1987-11-03 | 1989-10-12 | Behringwerke Ag | Gentechnische herstellung von anticoagulatorischem protein pp4 |
| DE68923107T2 (de) * | 1988-02-26 | 1996-01-18 | Biogen Inc | DNA-Sequenzen, rekombinante DNA-Moleküle und Verfahren zur Herstellung von Lipocortin III, IV, V, und VI. |
| US5324844A (en) * | 1989-04-19 | 1994-06-28 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
| ES2055234T3 (es) * | 1989-07-15 | 1994-08-16 | Boehringer Ingelheim Int | Agente con contenido de anticoagulante. |
| ES2045669T3 (es) * | 1989-07-15 | 1994-01-16 | Boehringer Ingelheim Int | Procedimiento para la purificacion de anexinas. |
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| CA2628558A1 (en) | 2007-06-28 |
| US7635678B2 (en) | 2009-12-22 |
| US20070054855A1 (en) | 2007-03-08 |
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| WO2007073509A2 (en) | 2007-06-28 |
| EP1957095A4 (en) | 2009-11-11 |
| EP1957095A2 (en) | 2008-08-20 |
| AU2006327095A2 (en) | 2008-10-09 |
| AU2006327095A1 (en) | 2007-06-28 |
| WO2007073509A8 (en) | 2008-10-02 |
| US20070207150A1 (en) | 2007-09-06 |
| US20060105952A1 (en) | 2006-05-18 |
| WO2007073509A3 (en) | 2007-11-29 |
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