JP2009513658A - メラニン凝集ホルモン受容体−１拮抗薬としてのチエノピリミジノン誘導体 - Google Patents

メラニン凝集ホルモン受容体−１拮抗薬としてのチエノピリミジノン誘導体 Download PDF

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Publication number
JP2009513658A
JP2009513658A JP2008537932A JP2008537932A JP2009513658A JP 2009513658 A JP2009513658 A JP 2009513658A JP 2008537932 A JP2008537932 A JP 2008537932A JP 2008537932 A JP2008537932 A JP 2008537932A JP 2009513658 A JP2009513658 A JP 2009513658A
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compound
mmol
group
hydrogen
formula
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JP2009513658A5 (https=
Inventor
ウィリアム・エヌ・ウォッシュバーン
アンドレス・エセ・エルナンデス
マーク・シー・マンフレディ
ジェフリー・エイ・ロブル
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2008537932A 2005-10-26 2006-10-26 メラニン凝集ホルモン受容体−１拮抗薬としてのチエノピリミジノン誘導体 Withdrawn JP2009513658A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73045305P 2005-10-26 2005-10-26
US11/586,255 US8618115B2 (en) 2005-10-26 2006-10-25 Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
PCT/US2006/041725 WO2007050726A2 (en) 2005-10-26 2006-10-26 Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists

Publications (2)

Publication Number Publication Date
JP2009513658A true JP2009513658A (ja) 2009-04-02
JP2009513658A5 JP2009513658A5 (https=) 2009-12-17

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ID=37888159

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008537932A Withdrawn JP2009513658A (ja) 2005-10-26 2006-10-26 メラニン凝集ホルモン受容体−１拮抗薬としてのチエノピリミジノン誘導体

Country Status (16)

Country Link
US (1) US8618115B2 (https=)
EP (2) EP2298776A1 (https=)
JP (1) JP2009513658A (https=)
KR (1) KR20080067681A (https=)
AR (1) AR056155A1 (https=)
AU (1) AU2006306140A1 (https=)
BR (1) BRPI0617945A2 (https=)
CA (1) CA2627653A1 (https=)
EA (1) EA016126B1 (https=)
GE (1) GEP20115213B (https=)
IL (1) IL190898A0 (https=)
NO (1) NO20081772L (https=)
NZ (1) NZ567659A (https=)
PE (1) PE20070532A1 (https=)
TW (1) TW200728289A (https=)
WO (1) WO2007050726A2 (https=)

Cited By (1)

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JP2023520924A (ja) * 2020-04-08 2023-05-22 リミックス セラピューティクス インコーポレイテッド スプライシングを調節するための化合物及び方法

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WO2007050726A3 (en) 2007-08-30
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AR056155A1 (es) 2007-09-19
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GEP20115213B (en) 2011-05-10
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US20070093509A1 (en) 2007-04-26
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