BRPI0617945A2 - compostos derivados de tienopirimidinona tais como os antagonistas do receptor-1 de hormÈnio de concentração da melanina, uso dos mesmos e composição e combinação farmacêuticas - Google Patents

compostos derivados de tienopirimidinona tais como os antagonistas do receptor-1 de hormÈnio de concentração da melanina, uso dos mesmos e composição e combinação farmacêuticas Download PDF

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Publication number
BRPI0617945A2
BRPI0617945A2 BRPI0617945-2A BRPI0617945A BRPI0617945A2 BR PI0617945 A2 BRPI0617945 A2 BR PI0617945A2 BR PI0617945 A BRPI0617945 A BR PI0617945A BR PI0617945 A2 BRPI0617945 A2 BR PI0617945A2
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formula
original document
document page
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BRPI0617945-2A
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English (en)
Portuguese (pt)
Inventor
N. Washburn William
S. Hernandez Andres
C. Manfredi Mark
A. Robl Jeffrey
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Bristol-Myers Squibb Company
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Publication of BRPI0617945A2 publication Critical patent/BRPI0617945A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BRPI0617945-2A 2005-10-26 2006-10-26 compostos derivados de tienopirimidinona tais como os antagonistas do receptor-1 de hormÈnio de concentração da melanina, uso dos mesmos e composição e combinação farmacêuticas BRPI0617945A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73045305P 2005-10-26 2005-10-26
US60/730,453 2005-10-26
US11/586,255 US8618115B2 (en) 2005-10-26 2006-10-25 Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
US11/586,255 2006-10-25
PCT/US2006/041725 WO2007050726A2 (en) 2005-10-26 2006-10-26 Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists

Publications (1)

Publication Number Publication Date
BRPI0617945A2 true BRPI0617945A2 (pt) 2011-08-09

Family

ID=37888159

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0617945-2A BRPI0617945A2 (pt) 2005-10-26 2006-10-26 compostos derivados de tienopirimidinona tais como os antagonistas do receptor-1 de hormÈnio de concentração da melanina, uso dos mesmos e composição e combinação farmacêuticas

Country Status (16)

Country Link
US (1) US8618115B2 (https=)
EP (2) EP1948665B1 (https=)
JP (1) JP2009513658A (https=)
KR (1) KR20080067681A (https=)
AR (1) AR056155A1 (https=)
AU (1) AU2006306140A1 (https=)
BR (1) BRPI0617945A2 (https=)
CA (1) CA2627653A1 (https=)
EA (1) EA016126B1 (https=)
GE (1) GEP20115213B (https=)
IL (1) IL190898A0 (https=)
NO (1) NO20081772L (https=)
NZ (1) NZ567659A (https=)
PE (1) PE20070532A1 (https=)
TW (1) TW200728289A (https=)
WO (1) WO2007050726A2 (https=)

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JP2010525077A (ja) * 2007-04-25 2010-07-22 ブリストル−マイヤーズ スクイブ カンパニー 非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト
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PE20091928A1 (es) * 2008-05-29 2009-12-31 Bristol Myers Squibb Co Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
WO2010003624A2 (en) 2008-07-09 2010-01-14 Sanofi-Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
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NO20081772L (no) 2008-05-19
IL190898A0 (en) 2008-11-03
US8618115B2 (en) 2013-12-31
TW200728289A (en) 2007-08-01
GEP20115213B (en) 2011-05-10
EA016126B1 (ru) 2012-02-28
AR056155A1 (es) 2007-09-19
EP1948665B1 (en) 2013-02-27
CA2627653A1 (en) 2007-05-03
KR20080067681A (ko) 2008-07-21
WO2007050726A2 (en) 2007-05-03
EP2298776A1 (en) 2011-03-23
NZ567659A (en) 2011-06-30
EA200801165A1 (ru) 2008-10-30
EP1948665A2 (en) 2008-07-30
AU2006306140A1 (en) 2007-05-03
WO2007050726A3 (en) 2007-08-30
JP2009513658A (ja) 2009-04-02
US20070093509A1 (en) 2007-04-26

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