AU2006306140A1 - Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists - Google Patents

Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists Download PDF

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Publication number
AU2006306140A1
AU2006306140A1 AU2006306140A AU2006306140A AU2006306140A1 AU 2006306140 A1 AU2006306140 A1 AU 2006306140A1 AU 2006306140 A AU2006306140 A AU 2006306140A AU 2006306140 A AU2006306140 A AU 2006306140A AU 2006306140 A1 AU2006306140 A1 AU 2006306140A1
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AU
Australia
Prior art keywords
pct
ome
nmr
group
compound according
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Abandoned
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AU2006306140A
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English (en)
Inventor
Andres S. Hernandez
Mark C. Manfredi
Jeffrey A. Robl
William N. Washburn
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU2006306140A1 publication Critical patent/AU2006306140A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2006306140A 2005-10-26 2006-10-26 Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists Abandoned AU2006306140A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73045305P 2005-10-26 2005-10-26
US60/730,453 2005-10-26
US11/586,255 2006-10-25
US11/586,255 US8618115B2 (en) 2005-10-26 2006-10-25 Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
PCT/US2006/041725 WO2007050726A2 (en) 2005-10-26 2006-10-26 Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists

Publications (1)

Publication Number Publication Date
AU2006306140A1 true AU2006306140A1 (en) 2007-05-03

Family

ID=37888159

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006306140A Abandoned AU2006306140A1 (en) 2005-10-26 2006-10-26 Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists

Country Status (16)

Country Link
US (1) US8618115B2 (https=)
EP (2) EP2298776A1 (https=)
JP (1) JP2009513658A (https=)
KR (1) KR20080067681A (https=)
AR (1) AR056155A1 (https=)
AU (1) AU2006306140A1 (https=)
BR (1) BRPI0617945A2 (https=)
CA (1) CA2627653A1 (https=)
EA (1) EA016126B1 (https=)
GE (1) GEP20115213B (https=)
IL (1) IL190898A0 (https=)
NO (1) NO20081772L (https=)
NZ (1) NZ567659A (https=)
PE (1) PE20070532A1 (https=)
TW (1) TW200728289A (https=)
WO (1) WO2007050726A2 (https=)

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US20080153810A1 (en) * 2006-11-15 2008-06-26 Forest Laboratories Holdings Limited Indazole derivatives useful as melanin concentrating receptor ligands
US7851622B2 (en) * 2007-04-25 2010-12-14 Bristol-Myers Squibb Company Non-basic melanin concentrating hormone receptor-1 antagonists
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PE20091928A1 (es) * 2008-05-29 2009-12-31 Bristol Myers Squibb Co Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
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CN102272135A (zh) * 2008-10-08 2011-12-07 百时美施贵宝公司 唑并吡咯酮黑色素浓集激素受体-1拮抗剂
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US8618115B2 (en) 2013-12-31
WO2007050726A3 (en) 2007-08-30
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IL190898A0 (en) 2008-11-03
BRPI0617945A2 (pt) 2011-08-09
AR056155A1 (es) 2007-09-19
EA200801165A1 (ru) 2008-10-30
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US20070093509A1 (en) 2007-04-26
WO2007050726A2 (en) 2007-05-03
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