NO20081772L - Ikke-basiske antagonister av melaninkonsentrerende hormon-reseptor-1 - Google Patents
Ikke-basiske antagonister av melaninkonsentrerende hormon-reseptor-1Info
- Publication number
- NO20081772L NO20081772L NO20081772A NO20081772A NO20081772L NO 20081772 L NO20081772 L NO 20081772L NO 20081772 A NO20081772 A NO 20081772A NO 20081772 A NO20081772 A NO 20081772A NO 20081772 L NO20081772 L NO 20081772L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- present application
- melanin
- antagonists
- basic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Abstract
Foreliggende søknad tilveiebringer forbindelser, inkludert alle stereoisomerer, solvater, prodrugs og farmasøytisk akseptable former derav, i henhold til Formel I. Dessuten tilveiebringer foreliggende søknad farmasøytiske preparater som inneholder minst én forbindelse med formel I og eventuelt minst ett ytterligere terapeutisk middel. Foreliggende søknad tilveiebringer også metoder for behandling av en pasient som lider av en MCHR-1-modulert sykdom eller lidelse, som for eksempel fedme, diabetes, depresjon eller angst, ved administrering av en terapeutisk effektiv dose av en forbindelse med formel I.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73045305P | 2005-10-26 | 2005-10-26 | |
US11/586,255 US8618115B2 (en) | 2005-10-26 | 2006-10-25 | Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them |
PCT/US2006/041725 WO2007050726A2 (en) | 2005-10-26 | 2006-10-26 | Thienopyrimidinone derivatives as melanin concentrating hormone receptor-1 antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20081772L true NO20081772L (no) | 2008-05-19 |
Family
ID=37888159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081772A NO20081772L (no) | 2005-10-26 | 2008-04-11 | Ikke-basiske antagonister av melaninkonsentrerende hormon-reseptor-1 |
Country Status (16)
Country | Link |
---|---|
US (1) | US8618115B2 (no) |
EP (2) | EP2298776A1 (no) |
JP (1) | JP2009513658A (no) |
KR (1) | KR20080067681A (no) |
AR (1) | AR056155A1 (no) |
AU (1) | AU2006306140A1 (no) |
BR (1) | BRPI0617945A2 (no) |
CA (1) | CA2627653A1 (no) |
EA (1) | EA016126B1 (no) |
GE (1) | GEP20115213B (no) |
IL (1) | IL190898A0 (no) |
NO (1) | NO20081772L (no) |
NZ (1) | NZ567659A (no) |
PE (1) | PE20070532A1 (no) |
TW (1) | TW200728289A (no) |
WO (1) | WO2007050726A2 (no) |
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US7285557B2 (en) * | 2001-10-15 | 2007-10-23 | Smithkline Beecham P.L.C. | Pyrimidinones as melanin concentrating hormone receptor 1 |
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US20080153810A1 (en) * | 2006-11-15 | 2008-06-26 | Forest Laboratories Holdings Limited | Indazole derivatives useful as melanin concentrating receptor ligands |
EP2142554B1 (en) * | 2007-04-25 | 2015-01-14 | Bristol-Myers Squibb Company | Non-basic melanin concentrating hormone receptor-1 antagonists |
WO2009097995A1 (de) * | 2008-02-07 | 2009-08-13 | Sanofi-Aventis | Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
PE20091928A1 (es) * | 2008-05-29 | 2009-12-31 | Bristol Myers Squibb Co | Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos |
TW201014822A (en) | 2008-07-09 | 2010-04-16 | Sanofi Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
CN102272135A (zh) * | 2008-10-08 | 2011-12-07 | 百时美施贵宝公司 | 唑并吡咯酮黑色素浓集激素受体-1拮抗剂 |
WO2010042682A1 (en) | 2008-10-08 | 2010-04-15 | Bristol-Myers Squibb Company | Azolotriazinone melanin concentrating hormone receptor-1 antagonists |
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EP2406233B1 (en) | 2009-03-09 | 2013-11-13 | Bristol-Myers Squibb Company | Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists |
US8563583B2 (en) | 2009-03-09 | 2013-10-22 | Bristol-Myers Squibb Company | Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists |
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WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
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CN107216339B (zh) * | 2016-03-22 | 2021-05-04 | 中国科学院上海药物研究所 | 一种dppiv抑制剂马来酸盐的多晶型及其制备方法 |
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-
2006
- 2006-10-25 US US11/586,255 patent/US8618115B2/en active Active
- 2006-10-25 AR ARP060104665A patent/AR056155A1/es not_active Application Discontinuation
- 2006-10-26 TW TW095139575A patent/TW200728289A/zh unknown
- 2006-10-26 BR BRPI0617945-2A patent/BRPI0617945A2/pt not_active IP Right Cessation
- 2006-10-26 KR KR1020087012373A patent/KR20080067681A/ko not_active Application Discontinuation
- 2006-10-26 EP EP10013754A patent/EP2298776A1/en not_active Withdrawn
- 2006-10-26 AU AU2006306140A patent/AU2006306140A1/en not_active Abandoned
- 2006-10-26 PE PE2006001304A patent/PE20070532A1/es not_active Application Discontinuation
- 2006-10-26 GE GEAP200610710A patent/GEP20115213B/en unknown
- 2006-10-26 EP EP06817387A patent/EP1948665B1/en active Active
- 2006-10-26 CA CA002627653A patent/CA2627653A1/en not_active Abandoned
- 2006-10-26 JP JP2008537932A patent/JP2009513658A/ja not_active Withdrawn
- 2006-10-26 NZ NZ567659A patent/NZ567659A/en not_active IP Right Cessation
- 2006-10-26 EA EA200801165A patent/EA016126B1/ru not_active IP Right Cessation
- 2006-10-26 WO PCT/US2006/041725 patent/WO2007050726A2/en active Application Filing
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2008
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WO2007050726A2 (en) | 2007-05-03 |
NZ567659A (en) | 2011-06-30 |
US20070093509A1 (en) | 2007-04-26 |
EP2298776A1 (en) | 2011-03-23 |
EA200801165A1 (ru) | 2008-10-30 |
IL190898A0 (en) | 2008-11-03 |
CA2627653A1 (en) | 2007-05-03 |
PE20070532A1 (es) | 2007-06-14 |
EP1948665A2 (en) | 2008-07-30 |
EA016126B1 (ru) | 2012-02-28 |
AU2006306140A1 (en) | 2007-05-03 |
AR056155A1 (es) | 2007-09-19 |
BRPI0617945A2 (pt) | 2011-08-09 |
GEP20115213B (en) | 2011-05-10 |
JP2009513658A (ja) | 2009-04-02 |
US8618115B2 (en) | 2013-12-31 |
EP1948665B1 (en) | 2013-02-27 |
TW200728289A (en) | 2007-08-01 |
KR20080067681A (ko) | 2008-07-21 |
WO2007050726A3 (en) | 2007-08-30 |
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