JP2009511034A5 - - Google Patents
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- Publication number
- JP2009511034A5 JP2009511034A5 JP2008535031A JP2008535031A JP2009511034A5 JP 2009511034 A5 JP2009511034 A5 JP 2009511034A5 JP 2008535031 A JP2008535031 A JP 2008535031A JP 2008535031 A JP2008535031 A JP 2008535031A JP 2009511034 A5 JP2009511034 A5 JP 2009511034A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleotides
- independently selected
- integer
- uuu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72630505P | 2005-10-12 | 2005-10-12 | |
| US75191705P | 2005-12-20 | 2005-12-20 | |
| PCT/EP2006/067334 WO2007042554A2 (en) | 2005-10-12 | 2006-10-12 | Methods and compositions for treating immune disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009511034A JP2009511034A (ja) | 2009-03-19 |
| JP2009511034A5 true JP2009511034A5 (enExample) | 2009-11-26 |
Family
ID=37770873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008535031A Pending JP2009511034A (ja) | 2005-10-12 | 2006-10-12 | 免疫異常を治療するための方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090169472A1 (enExample) |
| EP (1) | EP1937812A2 (enExample) |
| JP (1) | JP2009511034A (enExample) |
| KR (1) | KR20080065656A (enExample) |
| AU (1) | AU2006301230A1 (enExample) |
| BR (1) | BRPI0617254A2 (enExample) |
| CA (1) | CA2625488A1 (enExample) |
| EA (1) | EA200801045A1 (enExample) |
| WO (1) | WO2007042554A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US7662949B2 (en) | 2005-11-25 | 2010-02-16 | Coley Pharmaceutical Gmbh | Immunostimulatory oligoribonucleotides |
| HUE051267T2 (hu) | 2005-12-13 | 2021-03-01 | Harvard College | Sejttranszplantációs állványok |
| EP1996935B1 (en) | 2006-02-23 | 2011-09-14 | Yale University | Drug resistance to plant alkaloids based upon myd88 status in a cell and methods of inhibiting signaling through the tlr-4:myd88 pathway |
| DE102006035618A1 (de) * | 2006-07-31 | 2008-02-07 | Curevac Gmbh | Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz |
| EP2046954A2 (en) | 2006-07-31 | 2009-04-15 | Curevac GmbH | NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT |
| AU2007287430B2 (en) * | 2006-08-23 | 2011-07-21 | Kudos Pharmaceuticals Limited | 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors |
| CA2664156A1 (en) * | 2006-09-27 | 2008-04-03 | Coley Pharmaceutical Group, Inc. | Compositions of tlr ligands and antivirals |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| JP5753382B2 (ja) * | 2007-11-06 | 2015-07-22 | アディウティーダ ファーマシューティカルズ ゲーエムベーハー | 修飾されたオリゴリン酸基を含有する免疫賦活オリゴリボヌクレオチドアナログ |
| CA2710534C (en) * | 2008-01-31 | 2018-09-04 | Curevac Gmbh | Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant |
| JP5690143B2 (ja) | 2008-02-13 | 2015-03-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 持続的細胞プログラミング装置 |
| US8772243B2 (en) | 2008-08-20 | 2014-07-08 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for predicting the response to anti-cancer treatment with an agonist of TLR7 or an agonist of TLR8 |
| WO2010037408A1 (en) | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
| US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
| JP5948327B2 (ja) | 2010-07-30 | 2016-07-06 | キュアヴァック アーゲー | トランスフェクションおよび免疫刺激のためのジスルフィド架橋されたカチオン性成分との核酸の複合体形成 |
| US11202759B2 (en) | 2010-10-06 | 2021-12-21 | President And Fellows Of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
| GB201021867D0 (en) | 2010-12-23 | 2011-02-02 | Mologen Ag | Non-coding immunomodulatory DNA construct |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| PT2838515T (pt) | 2012-04-16 | 2020-02-25 | Harvard College | Composições de sílica mesoporosa para modular respostas imunológicas |
| US9868955B2 (en) | 2012-09-29 | 2018-01-16 | Dynavax Technologies Corporation | Human toll-like receptor inhibitors and methods of use thereof |
| US9228184B2 (en) | 2012-09-29 | 2016-01-05 | Dynavax Technologies Corporation | Human toll-like receptor inhibitors and methods of use thereof |
| KR101441415B1 (ko) * | 2013-03-11 | 2014-09-24 | 국방과학연구소 | 신규한 ｓｉＲＮＡ, 이를 이용한 오소폭스바이러스에 대한 항바이러스 조성물 |
| SG11201510746WA (en) | 2013-08-21 | 2016-03-30 | Curevac Ag | Respiratory syncytial virus (rsv) vaccine |
| WO2015149944A2 (en) | 2014-04-01 | 2015-10-08 | Curevac Gmbh | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
| JP7348708B2 (ja) | 2014-04-30 | 2023-09-21 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 組み合わせワクチン装置および癌細胞を殺滅する方法 |
| KR101643947B1 (ko) * | 2014-06-27 | 2016-07-29 | 건국대학교 산학협력단 | gHA1 단백질에 특이적으로 결합하는 RNA 앱타머 및 그를 포함하는 약학 조성물 |
| EP3250250A4 (en) | 2015-01-30 | 2019-05-22 | President and Fellows of Harvard College | PERITUMORAL AND INTRATUMORAL MATERIALS FOR CANCER THERAPY |
| WO2016164705A1 (en) | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Immune cell trapping devices and methods for making and using the same |
| LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
| GB2542425A (en) | 2015-09-21 | 2017-03-22 | Mologen Ag | Means for the treatment of HIV |
| JP7138864B2 (ja) | 2016-02-06 | 2022-09-20 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫を再構成するための造血ニッチの再現 |
| JP2019522486A (ja) | 2016-07-13 | 2019-08-15 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 抗原提示細胞模倣足場およびそれを作製および使用するための方法 |
| CA3032505A1 (en) | 2016-08-02 | 2018-02-08 | President And Fellows Of Harvard College | Biomaterials for modulating immune responses |
| SG11202001709WA (en) * | 2017-08-31 | 2020-03-30 | Mologen Ag | Tlr-9 agonists for modulation of tumor microenvironment |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| WO2021061837A1 (en) | 2019-09-23 | 2021-04-01 | President And Fellows Of Harvard College | Biomaterial-based antigen free vaccine and the use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683874A (en) * | 1991-03-27 | 1997-11-04 | Research Corporation Technologies, Inc. | Single-stranded circular oligonucleotides capable of forming a triplex with a target sequence |
| FR2814370B1 (fr) * | 2000-09-22 | 2004-08-20 | Centre Nat Rech Scient | Utilisation d'un complexe acide nucleique/pei pour le ciblage de cellules souches du cerveau |
| AU2003230806B2 (en) * | 2002-04-04 | 2009-05-07 | Zoetis Belgium S.A. | Immunostimulatory G,U-containing oligoribonucleotides |
| US20050256073A1 (en) * | 2004-02-19 | 2005-11-17 | Coley Pharmaceutical Group, Inc. | Immunostimulatory viral RNA oligonucleotides |
| US20050197312A1 (en) * | 2004-03-03 | 2005-09-08 | Kevin Fitzgerald | Transcription factor RNA interference reagents and methods of use thereof |
| US20060241076A1 (en) * | 2005-04-26 | 2006-10-26 | Coley Pharmaceutical Gmbh | Modified oligoribonucleotide analogs with enhanced immunostimulatory activity |
-
2006
- 2006-10-12 JP JP2008535031A patent/JP2009511034A/ja active Pending
- 2006-10-12 AU AU2006301230A patent/AU2006301230A1/en not_active Abandoned
- 2006-10-12 EP EP06807200A patent/EP1937812A2/en not_active Withdrawn
- 2006-10-12 KR KR1020087011347A patent/KR20080065656A/ko not_active Ceased
- 2006-10-12 BR BRPI0617254-7A patent/BRPI0617254A2/pt not_active IP Right Cessation
- 2006-10-12 US US12/088,752 patent/US20090169472A1/en not_active Abandoned
- 2006-10-12 EA EA200801045A patent/EA200801045A1/ru unknown
- 2006-10-12 CA CA002625488A patent/CA2625488A1/en not_active Abandoned
- 2006-10-12 WO PCT/EP2006/067334 patent/WO2007042554A2/en not_active Ceased
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