JP2009502878A - ラパチョ抽出物を含有する耳鼻科用溶液 - Google Patents
ラパチョ抽出物を含有する耳鼻科用溶液 Download PDFInfo
- Publication number
- JP2009502878A JP2009502878A JP2008523369A JP2008523369A JP2009502878A JP 2009502878 A JP2009502878 A JP 2009502878A JP 2008523369 A JP2008523369 A JP 2008523369A JP 2008523369 A JP2008523369 A JP 2008523369A JP 2009502878 A JP2009502878 A JP 2009502878A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- rapacho
- preparation according
- otolaryngological
- lapacho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0204—Specific forms not provided for by any of groups A61K8/0208 - A61K8/14
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fats And Perfumes (AREA)
Abstract
Description
水 5〜90%
薬草のラパチョ抽出物 5〜90%
水 89.8%
ニパギン 0.2%
水酸化ナトリウム pH6.5とする
10kgの微粉砕したラパチョの樹皮(タベブイア種)を、空気を有しない状態での連続した攪拌下、90kgの水性溶媒(pHを7.5に調整)中で、1〜3時間、65〜70℃で加温する。その後、この溶液を、20℃に冷却し、その後、濾過する。濾過物を採取し、保存料(0.2%のパラベン混合物)を添加する。上記の溶液を、最終的な製剤の調製に利用し得る。
10kgの微粉砕したラパチョの樹皮(タベブイア種)を、空気を有しない状態での連続した攪拌下、90kgの水性溶媒(pHを7.5に調整)中で、1〜3時間、65〜70℃で加温する。その後、この溶液を、20℃に冷却し、その後、濾過する。濾過物を採取し、保存料(0.2%のパラベン混合物)を添加する。その後、上記の溶液に、1〜70%(p/p)の濃度で、エタノール性、グリセロール性、及び/又は親水性の抽出物を添加する。上記の溶液を、最終的な製剤の調製に利用し得る。
Claims (10)
- ラパチョ抽出物を含有する耳鼻科用製剤。
- 前記のラパチョ抽出物は、ラパチョの樹皮を極性溶媒で処理することにより、得られることを特徴とする請求項1に記載の製剤。
- 前記の抽出物は、ラパチョの樹皮を非極性溶媒で処理することにより、得られることを特徴とする請求項1に記載の製剤。
- 前記の抽出物には、水に不溶のキノンを添加することを特徴とする請求項2に記載の製剤。
- 抗炎症剤、防腐剤、植物由来の抽出物、フラボノイド、ビタミン、保存料をも有することを特徴とする請求項1乃至4のいずれか一項に記載の製剤。
- ラパチョ抽出物 5〜90%
水 5〜90%
薬草のラパチョ抽出物 5〜90%
を含むことを特徴とする請求項1乃至5のいずれか一項に記載の製剤。 - ラパチョ抽出物 10.0%
水 89.8%
ニパギン 0.2%
水酸化ナトリウム pH6.5とする
を含むことを特徴とする請求項1乃至6のいずれか一項に記載の製剤。 - 極性又は非極性の溶媒のいずれかにおいて耳鼻科用の溶液を調製するためのラパチョ抽出物の使用。
- 可変な量の液体を含有する点滴薬、ボトル及び/又はストリップ、ガス推進剤を含有若しくは含有しない異なるスプレー、ディスポーザブル又はそうではないゴム製シリンジの形態であることを特徴とする請求項1乃至8のいずれか一項に記載の製剤。
- 請求項1乃至7のいずれか一項に記載の製剤による、耳の管における耳垢を溶解し、分離し且つ除去する方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000533A ITTO20050533A1 (it) | 2005-07-29 | 2005-07-29 | Soluzioni otologiche a base di estratti di lapacho |
PCT/EP2006/064780 WO2007014912A1 (en) | 2005-07-29 | 2006-07-28 | Otological solutions containing lapacho extracts |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009502878A true JP2009502878A (ja) | 2009-01-29 |
JP2009502878A5 JP2009502878A5 (ja) | 2012-07-12 |
Family
ID=37243357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008523369A Pending JP2009502878A (ja) | 2005-07-29 | 2006-07-28 | ラパチョ抽出物を含有する耳鼻科用溶液 |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080220106A1 (ja) |
EP (1) | EP1912616B1 (ja) |
JP (1) | JP2009502878A (ja) |
KR (1) | KR20080039390A (ja) |
CN (1) | CN101232866A (ja) |
CA (1) | CA2616953A1 (ja) |
CY (1) | CY1118479T1 (ja) |
IL (1) | IL189213A (ja) |
IT (1) | ITTO20050533A1 (ja) |
MA (1) | MA29749B1 (ja) |
PL (1) | PL1912616T3 (ja) |
RU (1) | RU2426551C2 (ja) |
TN (1) | TNSN08034A1 (ja) |
WO (1) | WO2007014912A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4349356A1 (en) | 2022-10-06 | 2024-04-10 | Phytoitalia SRL | Method for the preparation of extracts enriched with saturated, monounsaturated and polyunsaturated long-chain fatty acids from tabebuia impetiginosa (lapacho) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09157157A (ja) * | 1995-12-01 | 1997-06-17 | Pola Chem Ind Inc | 医薬組成物 |
WO2000026207A1 (en) * | 1998-10-30 | 2000-05-11 | Euro - Pharma S.R.L. | Products for body hygiene based on lapacho extracts containing quercitine, their preparation and use |
WO2004035071A1 (en) * | 2002-10-17 | 2004-04-29 | Nakar, Herzl | Herbal medicine containing cyclodextrins for the treatment of ear disorders |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0696533B2 (ja) * | 1987-01-14 | 1994-11-30 | 北陸製薬株式会社 | キノロンカルボン酸の水性組成物 |
US5296472A (en) * | 1991-12-05 | 1994-03-22 | Vyrex Corporation | Methods for delipidation of skin and cerumen removal |
US6387169B1 (en) * | 2000-02-11 | 2002-05-14 | Mattel, Inc. | Guar gum based flowing gel play composition |
US20040101506A1 (en) * | 2002-11-25 | 2004-05-27 | Fust Charles A. | Composition for the prevention and treatment of inflammation of the ear |
US20080166436A1 (en) * | 2007-01-10 | 2008-07-10 | Apperon Inc. | Composition for normalizing otitis externa in mammals |
-
2005
- 2005-07-29 IT IT000533A patent/ITTO20050533A1/it unknown
-
2006
- 2006-07-28 WO PCT/EP2006/064780 patent/WO2007014912A1/en active Application Filing
- 2006-07-28 CA CA002616953A patent/CA2616953A1/en not_active Abandoned
- 2006-07-28 RU RU2008107712/15A patent/RU2426551C2/ru active
- 2006-07-28 CN CNA2006800276782A patent/CN101232866A/zh active Pending
- 2006-07-28 JP JP2008523369A patent/JP2009502878A/ja active Pending
- 2006-07-28 US US11/996,844 patent/US20080220106A1/en not_active Abandoned
- 2006-07-28 PL PL06792600T patent/PL1912616T3/pl unknown
- 2006-07-28 KR KR1020087002360A patent/KR20080039390A/ko not_active Application Discontinuation
- 2006-07-28 EP EP06792600.6A patent/EP1912616B1/en active Active
-
2008
- 2008-01-22 TN TNP2008000034A patent/TNSN08034A1/en unknown
- 2008-01-28 IL IL189213A patent/IL189213A/en active IP Right Grant
- 2008-02-22 MA MA30674A patent/MA29749B1/fr unknown
-
2016
- 2016-08-05 CY CY20161100770T patent/CY1118479T1/el unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09157157A (ja) * | 1995-12-01 | 1997-06-17 | Pola Chem Ind Inc | 医薬組成物 |
WO2000026207A1 (en) * | 1998-10-30 | 2000-05-11 | Euro - Pharma S.R.L. | Products for body hygiene based on lapacho extracts containing quercitine, their preparation and use |
WO2004035071A1 (en) * | 2002-10-17 | 2004-04-29 | Nakar, Herzl | Herbal medicine containing cyclodextrins for the treatment of ear disorders |
Also Published As
Publication number | Publication date |
---|---|
IL189213A0 (en) | 2011-08-01 |
TNSN08034A1 (en) | 2009-07-14 |
ITTO20050533A1 (it) | 2007-01-30 |
CY1118479T1 (el) | 2017-07-12 |
US20080220106A1 (en) | 2008-09-11 |
EP1912616B1 (en) | 2016-05-11 |
EP1912616A1 (en) | 2008-04-23 |
RU2008107712A (ru) | 2009-09-10 |
CN101232866A (zh) | 2008-07-30 |
IL189213A (en) | 2013-11-28 |
PL1912616T3 (pl) | 2017-03-31 |
MA29749B1 (fr) | 2008-09-01 |
CA2616953A1 (en) | 2007-02-08 |
KR20080039390A (ko) | 2008-05-07 |
RU2426551C2 (ru) | 2011-08-20 |
WO2007014912A1 (en) | 2007-02-08 |
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