JP2009291208A5 - - Google Patents
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- Publication number
- JP2009291208A5 JP2009291208A5 JP2009192620A JP2009192620A JP2009291208A5 JP 2009291208 A5 JP2009291208 A5 JP 2009291208A5 JP 2009192620 A JP2009192620 A JP 2009192620A JP 2009192620 A JP2009192620 A JP 2009192620A JP 2009291208 A5 JP2009291208 A5 JP 2009291208A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- lysozyme
- composition
- seq
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 61
- 102000004196 processed proteins & peptides Human genes 0.000 claims 61
- 108090000765 processed proteins & peptides Proteins 0.000 claims 61
- 238000000034 method Methods 0.000 claims 23
- 229960000274 lysozyme Drugs 0.000 claims 21
- 239000004325 lysozyme Substances 0.000 claims 21
- 239000000203 mixture Substances 0.000 claims 21
- 108010014251 Muramidase Proteins 0.000 claims 19
- 102000016943 Muramidase Human genes 0.000 claims 19
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims 19
- 235000010335 lysozyme Nutrition 0.000 claims 19
- 101001018100 Homo sapiens Lysozyme C Proteins 0.000 claims 13
- 238000003556 assay Methods 0.000 claims 12
- 239000012530 fluid Substances 0.000 claims 10
- 239000002245 particle Substances 0.000 claims 10
- 239000013610 patient sample Substances 0.000 claims 9
- 150000001413 amino acids Chemical class 0.000 claims 7
- 239000012472 biological sample Substances 0.000 claims 7
- 244000052769 pathogen Species 0.000 claims 5
- 230000001717 pathogenic effect Effects 0.000 claims 5
- 239000007787 solid Substances 0.000 claims 4
- 241000589884 Treponema pallidum Species 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 230000035945 sensitivity Effects 0.000 claims 3
- 238000002965 ELISA Methods 0.000 claims 2
- 238000007818 agglutination assay Methods 0.000 claims 2
- 230000002223 anti-pathogen Effects 0.000 claims 2
- 210000003743 erythrocyte Anatomy 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 238000003018 immunoassay Methods 0.000 claims 2
- 239000010954 inorganic particle Substances 0.000 claims 2
- 235000013336 milk Nutrition 0.000 claims 2
- 210000004080 milk Anatomy 0.000 claims 2
- 239000008267 milk Substances 0.000 claims 2
- 230000005298 paramagnetic effect Effects 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 210000005253 yeast cell Anatomy 0.000 claims 2
- 206010003445 Ascites Diseases 0.000 claims 1
- 208000005228 Pericardial Effusion Diseases 0.000 claims 1
- 208000002151 Pleural effusion Diseases 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 241000282849 Ruminantia Species 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- -1 aqueous humor Substances 0.000 claims 1
- 210000001742 aqueous humor Anatomy 0.000 claims 1
- 210000003567 ascitic fluid Anatomy 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000002318 cardia Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 210000003022 colostrum Anatomy 0.000 claims 1
- 235000021277 colostrum Nutrition 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000002550 fecal effect Effects 0.000 claims 1
- 239000000706 filtrate Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 210000004912 pericardial fluid Anatomy 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 238000003127 radioimmunoassay Methods 0.000 claims 1
- 230000001850 reproductive effect Effects 0.000 claims 1
- 239000011347 resin Substances 0.000 claims 1
- 229920005989 resin Polymers 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 210000004243 sweat Anatomy 0.000 claims 1
- 210000001179 synovial fluid Anatomy 0.000 claims 1
- 208000006379 syphilis Diseases 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 238000007817 turbidimetric assay Methods 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 238000001262 western blot Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03380307.3 | 2003-12-23 | ||
| EP03380307 | 2003-12-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546204A Division JP5414972B2 (ja) | 2003-12-23 | 2004-12-23 | 病原体感染の検出のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009291208A JP2009291208A (ja) | 2009-12-17 |
| JP2009291208A5 true JP2009291208A5 (cg-RX-API-DMAC7.html) | 2010-10-14 |
| JP5133306B2 JP5133306B2 (ja) | 2013-01-30 |
Family
ID=34707292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546204A Expired - Fee Related JP5414972B2 (ja) | 2003-12-23 | 2004-12-23 | 病原体感染の検出のための組成物および方法 |
| JP2009192620A Expired - Fee Related JP5133306B2 (ja) | 2003-12-23 | 2009-08-21 | 病原体感染の検出のための組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546204A Expired - Fee Related JP5414972B2 (ja) | 2003-12-23 | 2004-12-23 | 病原体感染の検出のための組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (6) | US7700727B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1724281B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5414972B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2405848T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005061532A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1724281B1 (en) * | 2003-12-23 | 2013-02-13 | Biokit S.A. | Pathogenic infection detection compositions and methods |
| US20060217893A1 (en) * | 2005-01-07 | 2006-09-28 | Yanbin Li | Method for detecting an unknown contaminant concentration in a substance |
| US20090148870A1 (en) * | 2006-05-18 | 2009-06-11 | Ericson Daniel G | Rapid Detection of Mycobacterium Tuberculosis and Antimicrobial Drug Resistance |
| US20100120016A1 (en) * | 2006-09-01 | 2010-05-13 | Yanbin Li | Methods and systems for detection of contaminants |
| CN102365295A (zh) * | 2009-01-30 | 2012-02-29 | 阿德利夫股份有限公司 | 构象动力肽 |
| CN101858914B (zh) * | 2010-05-19 | 2013-03-27 | 厦门大学附属中山医院 | 梅毒特异性总抗体胶体金免疫层析检测试剂条及其制备方法 |
| US20130266554A1 (en) * | 2010-09-16 | 2013-10-10 | Novozymes A/S | Lysozymes |
| RU2481101C2 (ru) * | 2010-12-15 | 2013-05-10 | Владимир Николаевич Иванов | Фармацевтическая композиция, содержащая ферменты: лизоцим, пероксидазу, повиаргол и липосомы, для местного применения |
| EP2537858A1 (en) | 2011-06-20 | 2012-12-26 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Small efficient cell penetrating peptides derived from the scorpion toxin maurocalcine |
| WO2013006795A2 (en) * | 2011-07-07 | 2013-01-10 | Humanitas International Foundation | Antiviral compositions and methods of their use |
| US20140228248A1 (en) * | 2011-09-28 | 2014-08-14 | Biomed Valley Discoveries, Inc. | Methods and compositions for detecting infections |
| WO2013085540A2 (en) * | 2011-12-09 | 2013-06-13 | The Ohio State University Research Foundation | Cry crystals for the production of antimicrobial proteins |
| US20130210747A1 (en) | 2012-02-13 | 2013-08-15 | University Of Southern California | Methods and Therapeutics Comprising Ligand-Targeted ELPs |
| US20150218280A1 (en) | 2012-08-10 | 2015-08-06 | University Of Southern California | CD20 scFv-ELPs METHODS AND THERAPEUTICS |
| US10597696B2 (en) | 2013-09-18 | 2020-03-24 | University Of Notre Dame Du Lac | Detection of Niemann-Pick disease comprising detection of lysozyme and cathepsins |
| CN104761621B (zh) * | 2014-01-06 | 2016-04-13 | 长春新悦然科技有限公司 | 一种抗菌蛋白 |
| KR101933217B1 (ko) | 2017-12-28 | 2018-12-27 | (주) 에빅스젠 | 피부 염증 억제용 펩티드 및 이를 포함하는 피부 염증 예방 또는 치료용 조성물 |
| CN111206025B (zh) * | 2020-02-28 | 2022-02-15 | 江南大学 | 一种比活提高的溶菌酶突变体 |
| US20230173030A1 (en) * | 2020-05-05 | 2023-06-08 | Phasebio Pharmaceuticals, Inc. | Vasoactive intestinal peptide fusion proteins for the treatment of covid-19 |
| CN114213551B (zh) * | 2021-12-03 | 2023-04-11 | 四川农业大学 | 一种高表达重组生物蛋白api及其制备方法和应用 |
| CN113881610B (zh) * | 2021-12-06 | 2022-02-25 | 北京量化健康科技有限公司 | 多形拟杆菌bp8e及其应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4065354A (en) * | 1974-10-10 | 1977-12-27 | Syva Company | Lysozyme conjugates for enzyme immunoassays |
| US4076797A (en) | 1976-09-28 | 1978-02-28 | Hoffmann-La Roche Inc. | Radioimmunoassay |
| US4294817A (en) | 1977-11-25 | 1981-10-13 | International Diagnostic Technology, Inc. | Method of fluoro immunoassay |
| US4288426A (en) | 1980-03-20 | 1981-09-08 | Research Corporation | Serological test for syphilis |
| JPS5871457A (ja) | 1981-10-23 | 1983-04-28 | Fujirebio Inc | 梅毒検査用試薬の製造法 |
| US4514498A (en) | 1982-05-26 | 1985-04-30 | The Board Of Regents, The University Of Texas System | Hybrid cell lines producing monoclonal antibodies directed against Treponema |
| US4740467A (en) | 1982-05-26 | 1988-04-26 | Board Of Regents, The University Of Texas | Methods for diagnosing syphilis |
| US4777133A (en) | 1984-06-11 | 1988-10-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Device for quantitative endpoint determination in immunofluorescence using microfluorophotometry |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4894328A (en) | 1986-03-26 | 1990-01-16 | Board Of Regents, The University Of Texas System | Immunodiagnostic test for syphilis and other treponemal infections |
| US5681934A (en) | 1986-09-30 | 1997-10-28 | Board Of Regents, The University Of Texas System | 47-kilodalton antigen of Treponema pallidum |
| US5350842A (en) | 1986-09-30 | 1994-09-27 | Board Of Regents, The University Of Texas System | DNAs encoding Treponema pallidum antigens |
| ES2120401T3 (es) * | 1986-11-17 | 1998-11-01 | Scios Inc | Proteina recombinante amiloide relacionados con la enfermedad de alzheimer. |
| US5008199A (en) | 1987-11-19 | 1991-04-16 | Warner-Lambert Company | Hybridoma cell line and monoclonal antibodies to Treponema denticola ATCC 33520 |
| US5055405A (en) | 1987-11-19 | 1991-10-08 | Warner-Lambert Company | Hybridoma cell line and monoclonal antibodies to Treponema species T. denticola JD-1 and Treponema 10A |
| NO177065C (no) * | 1988-09-26 | 1995-07-12 | Labofina Sa | Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym |
| US5514553A (en) | 1989-05-22 | 1996-05-07 | The United States Of America As Represented By The Secretary Of The Navy | Production of monoclonal antibodies to Treponema denticola by hybridoma TDII, IAA11 |
| US4959304A (en) | 1989-05-22 | 1990-09-25 | United States Of America As Represented By The Secretary Of The Navy | Production of monoclonal antibodies to treponema denticola by hybridoma TDIII, IIIBB2 |
| US5372928A (en) | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
| US4997932A (en) * | 1989-11-13 | 1991-03-05 | Boehringer Mannheim Corporation | Method and kit for purifying nucleic acids |
| US5474900A (en) | 1990-03-16 | 1995-12-12 | Sekisui Chemical Co., Ltd. | Process for preparing purified syphilis antigen from Treponema palljdum |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US6313094B1 (en) | 1990-12-11 | 2001-11-06 | Japan Energy Corporation | β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors |
| US5155022A (en) | 1991-02-08 | 1992-10-13 | Becton, Dickinson And Company | Assay for lyme disease |
| US5965702A (en) | 1991-10-21 | 1999-10-12 | Abbott Laboratories | Borrelia burgdorferi antigens and uses thereof |
| DE69432791T2 (de) | 1993-05-28 | 2004-06-03 | Baylor College Of Medicine, Houston | Verfahren und massenspektrometer zur desorption und ionisierung von analyten |
| US5578456A (en) | 1994-02-28 | 1996-11-26 | Fujirebio Inc. | Anti-treponema pallidum antibody immunoassay |
| US5635182A (en) * | 1994-06-16 | 1997-06-03 | Genetics Institute, Inc. | Method of detecting ligand interactions |
| US5962245A (en) * | 1995-04-05 | 1999-10-05 | The Picower Institute For Medical Research | Methods for detecting the presence of advanced glycosylation endproducts |
| EP0859841B1 (en) | 1995-08-18 | 2002-06-19 | MorphoSys AG | Protein/(poly)peptide libraries |
| DE19536166C1 (de) | 1995-09-29 | 1997-03-06 | Siegfried Dr Krell | Verfahren zur Bestimmung von Antikörpern gegen Treponema pallidum (Syphilis) |
| CA2193870C (en) * | 1995-12-25 | 2000-07-18 | Nobuyuki Ise | Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen |
| JPH10218895A (ja) * | 1997-02-14 | 1998-08-18 | Higeta Shoyu Co Ltd | 改変タンパク質、それをコードするｄｎａ、そのｄｎａを含む組換えベクター、その組換えベクターを含む形質転換体、改変タンパク質の製造法、抗トレポネーマ・パリダム抗体の測定法及び測定用試薬、梅毒感染診断薬並びに抗トレポネーマ・パリダム抗体の製造法 |
| EP0984065A4 (en) * | 1997-02-14 | 2002-07-24 | Higeta Shoyu Kk | MODIFIED PROTEINANTIGENT FROM TREPONEMA PALLADIUM. |
| DE19723463A1 (de) * | 1997-06-04 | 1998-12-10 | Dade Behring Marburg Gmbh | Immunchemische Bestimmung von multivalenten Analyten |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| DE19749973C1 (de) | 1997-11-05 | 1998-10-22 | Klaus Dr Duering | Lysozym-analoge Proteine und Peptide mit antimikrobieller Wirkung, ihre Herstellung und ihre Verwendung |
| US6083700A (en) * | 1998-06-26 | 2000-07-04 | Incyte Pharmaceuticals, Inc. | Human goose-type lysozyme |
| IT1319277B1 (it) * | 2000-10-24 | 2003-09-26 | Chiesi Farma Spa | Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer. |
| EP1724281B1 (en) * | 2003-12-23 | 2013-02-13 | Biokit S.A. | Pathogenic infection detection compositions and methods |
-
2004
- 2004-12-23 EP EP04805124A patent/EP1724281B1/en not_active Expired - Lifetime
- 2004-12-23 WO PCT/ES2004/000581 patent/WO2005061532A1/es not_active Ceased
- 2004-12-23 ES ES04805124T patent/ES2405848T3/es not_active Expired - Lifetime
- 2004-12-23 JP JP2006546204A patent/JP5414972B2/ja not_active Expired - Fee Related
-
2005
- 2005-04-27 US US11/116,144 patent/US7700727B2/en not_active Expired - Fee Related
- 2005-09-06 US US11/220,372 patent/US20060063149A1/en not_active Abandoned
-
2006
- 2006-04-05 US US11/398,377 patent/US20060269976A1/en not_active Abandoned
- 2006-04-06 US US11/398,937 patent/US20060286119A1/en not_active Abandoned
- 2006-04-06 US US11/398,889 patent/US20060270835A1/en not_active Abandoned
- 2006-04-06 US US11/398,884 patent/US20060275317A1/en not_active Abandoned
-
2009
- 2009-08-21 JP JP2009192620A patent/JP5133306B2/ja not_active Expired - Fee Related
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