ES2405848T3 - Composiciones y métodos para detección de infección patógena - Google Patents

Composiciones y métodos para detección de infección patógena Download PDF

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Publication number
ES2405848T3
ES2405848T3 ES04805124T ES04805124T ES2405848T3 ES 2405848 T3 ES2405848 T3 ES 2405848T3 ES 04805124 T ES04805124 T ES 04805124T ES 04805124 T ES04805124 T ES 04805124T ES 2405848 T3 ES2405848 T3 ES 2405848T3
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Prior art keywords
lysozyme
polypeptide
xaa xaa
type polypeptide
type
Prior art date
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Expired - Lifetime
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ES04805124T
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English (en)
Spanish (es)
Inventor
François Xavier BERTHET
Francesc Vayreda Casadevall
María Cruz SANZ
Teresa Llop Garcia
Angels Mor Olle
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Biokit SA
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Biokit SA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61P11/16Central respiratory analeptics
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    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
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    • A61P31/12Antivirals
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462Lysozyme (3.2.1.17)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
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    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
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    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
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    • GPHYSICS
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    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
ES04805124T 2003-12-23 2004-12-23 Composiciones y métodos para detección de infección patógena Expired - Lifetime ES2405848T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03380307 2003-12-23
EP03380307 2003-12-23
PCT/ES2004/000581 WO2005061532A1 (es) 2003-12-23 2004-12-23 Composiciones y procedimientos para detectar infección patógena

Publications (1)

Publication Number Publication Date
ES2405848T3 true ES2405848T3 (es) 2013-06-04

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ES04805124T Expired - Lifetime ES2405848T3 (es) 2003-12-23 2004-12-23 Composiciones y métodos para detección de infección patógena

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Country Link
US (6) US7700727B2 (cg-RX-API-DMAC7.html)
EP (1) EP1724281B1 (cg-RX-API-DMAC7.html)
JP (2) JP5414972B2 (cg-RX-API-DMAC7.html)
ES (1) ES2405848T3 (cg-RX-API-DMAC7.html)
WO (1) WO2005061532A1 (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1724281B1 (en) * 2003-12-23 2013-02-13 Biokit S.A. Pathogenic infection detection compositions and methods
US20060217893A1 (en) * 2005-01-07 2006-09-28 Yanbin Li Method for detecting an unknown contaminant concentration in a substance
US20090148870A1 (en) * 2006-05-18 2009-06-11 Ericson Daniel G Rapid Detection of Mycobacterium Tuberculosis and Antimicrobial Drug Resistance
US20100120016A1 (en) * 2006-09-01 2010-05-13 Yanbin Li Methods and systems for detection of contaminants
CN102365295A (zh) * 2009-01-30 2012-02-29 阿德利夫股份有限公司 构象动力肽
CN101858914B (zh) * 2010-05-19 2013-03-27 厦门大学附属中山医院 梅毒特异性总抗体胶体金免疫层析检测试剂条及其制备方法
US20130266554A1 (en) * 2010-09-16 2013-10-10 Novozymes A/S Lysozymes
RU2481101C2 (ru) * 2010-12-15 2013-05-10 Владимир Николаевич Иванов Фармацевтическая композиция, содержащая ферменты: лизоцим, пероксидазу, повиаргол и липосомы, для местного применения
EP2537858A1 (en) 2011-06-20 2012-12-26 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Small efficient cell penetrating peptides derived from the scorpion toxin maurocalcine
WO2013006795A2 (en) * 2011-07-07 2013-01-10 Humanitas International Foundation Antiviral compositions and methods of their use
US20140228248A1 (en) * 2011-09-28 2014-08-14 Biomed Valley Discoveries, Inc. Methods and compositions for detecting infections
WO2013085540A2 (en) * 2011-12-09 2013-06-13 The Ohio State University Research Foundation Cry crystals for the production of antimicrobial proteins
US20130210747A1 (en) 2012-02-13 2013-08-15 University Of Southern California Methods and Therapeutics Comprising Ligand-Targeted ELPs
US20150218280A1 (en) 2012-08-10 2015-08-06 University Of Southern California CD20 scFv-ELPs METHODS AND THERAPEUTICS
US10597696B2 (en) 2013-09-18 2020-03-24 University Of Notre Dame Du Lac Detection of Niemann-Pick disease comprising detection of lysozyme and cathepsins
CN104761621B (zh) * 2014-01-06 2016-04-13 长春新悦然科技有限公司 一种抗菌蛋白
KR101933217B1 (ko) 2017-12-28 2018-12-27 (주) 에빅스젠 피부 염증 억제용 펩티드 및 이를 포함하는 피부 염증 예방 또는 치료용 조성물
CN111206025B (zh) * 2020-02-28 2022-02-15 江南大学 一种比活提高的溶菌酶突变体
US20230173030A1 (en) * 2020-05-05 2023-06-08 Phasebio Pharmaceuticals, Inc. Vasoactive intestinal peptide fusion proteins for the treatment of covid-19
CN114213551B (zh) * 2021-12-03 2023-04-11 四川农业大学 一种高表达重组生物蛋白api及其制备方法和应用
CN113881610B (zh) * 2021-12-06 2022-02-25 北京量化健康科技有限公司 多形拟杆菌bp8e及其应用

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065354A (en) * 1974-10-10 1977-12-27 Syva Company Lysozyme conjugates for enzyme immunoassays
US4076797A (en) 1976-09-28 1978-02-28 Hoffmann-La Roche Inc. Radioimmunoassay
US4294817A (en) 1977-11-25 1981-10-13 International Diagnostic Technology, Inc. Method of fluoro immunoassay
US4288426A (en) 1980-03-20 1981-09-08 Research Corporation Serological test for syphilis
JPS5871457A (ja) 1981-10-23 1983-04-28 Fujirebio Inc 梅毒検査用試薬の製造法
US4514498A (en) 1982-05-26 1985-04-30 The Board Of Regents, The University Of Texas System Hybrid cell lines producing monoclonal antibodies directed against Treponema
US4740467A (en) 1982-05-26 1988-04-26 Board Of Regents, The University Of Texas Methods for diagnosing syphilis
US4777133A (en) 1984-06-11 1988-10-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Device for quantitative endpoint determination in immunofluorescence using microfluorophotometry
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4894328A (en) 1986-03-26 1990-01-16 Board Of Regents, The University Of Texas System Immunodiagnostic test for syphilis and other treponemal infections
US5681934A (en) 1986-09-30 1997-10-28 Board Of Regents, The University Of Texas System 47-kilodalton antigen of Treponema pallidum
US5350842A (en) 1986-09-30 1994-09-27 Board Of Regents, The University Of Texas System DNAs encoding Treponema pallidum antigens
ES2120401T3 (es) * 1986-11-17 1998-11-01 Scios Inc Proteina recombinante amiloide relacionados con la enfermedad de alzheimer.
US5008199A (en) 1987-11-19 1991-04-16 Warner-Lambert Company Hybridoma cell line and monoclonal antibodies to Treponema denticola ATCC 33520
US5055405A (en) 1987-11-19 1991-10-08 Warner-Lambert Company Hybridoma cell line and monoclonal antibodies to Treponema species T. denticola JD-1 and Treponema 10A
NO177065C (no) * 1988-09-26 1995-07-12 Labofina Sa Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
US5514553A (en) 1989-05-22 1996-05-07 The United States Of America As Represented By The Secretary Of The Navy Production of monoclonal antibodies to Treponema denticola by hybridoma TDII, IAA11
US4959304A (en) 1989-05-22 1990-09-25 United States Of America As Represented By The Secretary Of The Navy Production of monoclonal antibodies to treponema denticola by hybridoma TDIII, IIIBB2
US5372928A (en) 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
US4997932A (en) * 1989-11-13 1991-03-05 Boehringer Mannheim Corporation Method and kit for purifying nucleic acids
US5474900A (en) 1990-03-16 1995-12-12 Sekisui Chemical Co., Ltd. Process for preparing purified syphilis antigen from Treponema palljdum
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
US5155022A (en) 1991-02-08 1992-10-13 Becton, Dickinson And Company Assay for lyme disease
US5965702A (en) 1991-10-21 1999-10-12 Abbott Laboratories Borrelia burgdorferi antigens and uses thereof
DE69432791T2 (de) 1993-05-28 2004-06-03 Baylor College Of Medicine, Houston Verfahren und massenspektrometer zur desorption und ionisierung von analyten
US5578456A (en) 1994-02-28 1996-11-26 Fujirebio Inc. Anti-treponema pallidum antibody immunoassay
US5635182A (en) * 1994-06-16 1997-06-03 Genetics Institute, Inc. Method of detecting ligand interactions
US5962245A (en) * 1995-04-05 1999-10-05 The Picower Institute For Medical Research Methods for detecting the presence of advanced glycosylation endproducts
EP0859841B1 (en) 1995-08-18 2002-06-19 MorphoSys AG Protein/(poly)peptide libraries
DE19536166C1 (de) 1995-09-29 1997-03-06 Siegfried Dr Krell Verfahren zur Bestimmung von Antikörpern gegen Treponema pallidum (Syphilis)
CA2193870C (en) * 1995-12-25 2000-07-18 Nobuyuki Ise Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen
JPH10218895A (ja) * 1997-02-14 1998-08-18 Higeta Shoyu Co Ltd 改変タンパク質、それをコードするdna、そのdnaを含む組換えベクター、その組換えベクターを含む形質転換体、改変タンパク質の製造法、抗トレポネーマ・パリダム抗体の測定法及び測定用試薬、梅毒感染診断薬並びに抗トレポネーマ・パリダム抗体の製造法
EP0984065A4 (en) * 1997-02-14 2002-07-24 Higeta Shoyu Kk MODIFIED PROTEINANTIGENT FROM TREPONEMA PALLADIUM.
DE19723463A1 (de) * 1997-06-04 1998-12-10 Dade Behring Marburg Gmbh Immunchemische Bestimmung von multivalenten Analyten
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
DE19749973C1 (de) 1997-11-05 1998-10-22 Klaus Dr Duering Lysozym-analoge Proteine und Peptide mit antimikrobieller Wirkung, ihre Herstellung und ihre Verwendung
US6083700A (en) * 1998-06-26 2000-07-04 Incyte Pharmaceuticals, Inc. Human goose-type lysozyme
IT1319277B1 (it) * 2000-10-24 2003-09-26 Chiesi Farma Spa Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer.
EP1724281B1 (en) * 2003-12-23 2013-02-13 Biokit S.A. Pathogenic infection detection compositions and methods

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US20050277181A1 (en) 2005-12-15
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US20060063149A1 (en) 2006-03-23
WO2005061532A8 (es) 2005-08-04
US20060270835A1 (en) 2006-11-30
US20060275317A1 (en) 2006-12-07
US7700727B2 (en) 2010-04-20
US20060269976A1 (en) 2006-11-30
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US20060286119A1 (en) 2006-12-21

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