JP2009185063A5 - - Google Patents
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- JP2009185063A5 JP2009185063A5 JP2009120386A JP2009120386A JP2009185063A5 JP 2009185063 A5 JP2009185063 A5 JP 2009185063A5 JP 2009120386 A JP2009120386 A JP 2009120386A JP 2009120386 A JP2009120386 A JP 2009120386A JP 2009185063 A5 JP2009185063 A5 JP 2009185063A5
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- JP
- Japan
- Prior art keywords
- reagent
- organic synthesis
- synthesis reaction
- reaction
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003153 chemical reaction reagent Substances 0.000 claims 20
- 238000003786 synthesis reaction Methods 0.000 claims 19
- 238000000926 separation method Methods 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
- 238000006243 chemical reaction Methods 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 125000001309 chloro group Chemical group Cl* 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009120386A JP5113118B2 (ja) | 2006-03-24 | 2009-05-18 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006084019 | 2006-03-24 | ||
| JP2006084019 | 2006-03-24 | ||
| JP2009120386A JP5113118B2 (ja) | 2006-03-24 | 2009-05-18 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008511981A Division JPWO2007122847A1 (ja) | 2006-03-24 | 2007-02-19 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009185063A JP2009185063A (ja) | 2009-08-20 |
| JP2009185063A5 true JP2009185063A5 (https=) | 2011-04-14 |
| JP5113118B2 JP5113118B2 (ja) | 2013-01-09 |
Family
ID=38624764
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008511981A Pending JPWO2007122847A1 (ja) | 2006-03-24 | 2007-02-19 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
| JP2009120386A Active JP5113118B2 (ja) | 2006-03-24 | 2009-05-18 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008511981A Pending JPWO2007122847A1 (ja) | 2006-03-24 | 2007-02-19 | 有機合成用試薬、及び当該試薬を用いた有機合成反応方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8093435B2 (https=) |
| EP (1) | EP2003104B1 (https=) |
| JP (2) | JPWO2007122847A1 (https=) |
| CN (1) | CN101405240B (https=) |
| AU (1) | AU2007242276A1 (https=) |
| DK (1) | DK2003104T3 (https=) |
| ES (1) | ES2546808T3 (https=) |
| WO (1) | WO2007122847A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2546808T3 (es) * | 2006-03-24 | 2015-09-28 | Jitsubo Co., Ltd. | Reactivo para síntesis orgánica y método de reacción de síntesis orgánica con dicho reactivo |
| US8569453B2 (en) | 2009-03-12 | 2013-10-29 | Ajinomoto Co., Inc. | Fluorene compound |
| WO2010113939A1 (ja) | 2009-03-30 | 2010-10-07 | 味の素株式会社 | ジフェニルメタン化合物 |
| EP2518041A4 (en) | 2009-12-25 | 2013-12-11 | Ajinomoto Kk | benzyl |
| CN106220482B (zh) * | 2010-08-30 | 2020-01-07 | 味之素株式会社 | 含有支链的芳香族化合物 |
| JP6150726B2 (ja) | 2011-03-09 | 2017-06-21 | Jitsubo株式会社 | 新規な非ペプチド性架橋構造を含む架橋ペプチド、ならびに該架橋ペプチドの合成方法および該方法に用いる新規な有機化合物 |
| DK2711370T3 (en) | 2011-05-17 | 2018-02-26 | Ajinomoto Kk | PROCEDURE FOR THE PREPARATION OF OLIGONUCLEOTIDES |
| JP6112011B2 (ja) | 2011-05-31 | 2017-04-12 | 味の素株式会社 | ペプチドの製造方法 |
| JP6011528B2 (ja) | 2011-05-31 | 2016-10-19 | 味の素株式会社 | ペプチドの製造方法 |
| CN102584546A (zh) * | 2011-09-26 | 2012-07-18 | 盘锦兴福化工有限公司 | 2,3—二氟苯乙醚的合成方法 |
| US9057712B1 (en) | 2011-10-27 | 2015-06-16 | Copilot Ventures Fund Iii Llc | Methods of delivery of encapsulated perfluorocarbon taggants |
| US10214555B2 (en) | 2012-11-14 | 2019-02-26 | Takeda Pharmaceutical Company Limitjed | Method for liquid-phase synthesis of nucleic acid |
| CN107879960B (zh) | 2013-03-08 | 2021-06-22 | 诺华股份有限公司 | 用于传递活性成分的脂质和脂质组合物 |
| US9504747B2 (en) | 2013-03-08 | 2016-11-29 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| DK3015467T3 (da) | 2013-05-24 | 2025-02-10 | Ajinomoto Kk | Morpholino-oligonukleotidfremstillingsfremgangsmåde |
| US9365615B2 (en) | 2013-09-09 | 2016-06-14 | Jitsubo Co., Ltd. | Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method |
| CN113717239B (zh) | 2015-01-21 | 2024-12-24 | 味之素株式会社 | 沉淀促进剂以及使用其的沉淀方法 |
| CN107406480B (zh) * | 2015-03-04 | 2022-06-24 | Jitsubo株式会社 | 肽合成方法 |
| KR101889893B1 (ko) * | 2015-06-12 | 2018-08-22 | 애니젠 주식회사 | 선별적 용해도를 갖는 트리페닐메탄 유도체 및 그의 용도 |
| CN108697770B (zh) | 2015-12-21 | 2023-08-01 | 得克萨斯技术大学联合体 | 用于溶液相gap肽合成的系统和方法 |
| WO2018088527A1 (ja) | 2016-11-11 | 2018-05-17 | 積水メディカル株式会社 | 新規トリチル保護剤 |
| EP3480195A1 (en) | 2017-11-07 | 2019-05-08 | Bayer Animal Health GmbH | Method for the synthesis of cyclic depsipeptides |
| IL274283B2 (en) * | 2017-11-07 | 2025-03-01 | Bayer Animal Health Gmbh | Method for the synthesis of cyclic depsipeptides |
| JP6703668B2 (ja) | 2018-04-13 | 2020-06-03 | Jitsubo株式会社 | ペプチド合成方法 |
| US12024537B2 (en) | 2018-05-31 | 2024-07-02 | Sederma | Compositions and methods for chemical synthesis |
| WO2020159837A1 (en) | 2019-02-01 | 2020-08-06 | Gap Peptides Llc | Synthesis strategy for gap protecting group |
| JP7476798B2 (ja) | 2018-11-16 | 2024-05-01 | 味の素株式会社 | 分子内ｓ－ｓ結合を有する環化ペプチドの製造方法 |
| EP3916000B1 (en) | 2019-02-28 | 2026-04-08 | FUJIFILM Corporation | Method for producing peptide compound, protecting group-forming reagent, and aromatic heterocyclic compound |
| WO2020218497A1 (ja) | 2019-04-25 | 2020-10-29 | 味の素株式会社 | ペプチドの連続的製造方法 |
| JP7301965B2 (ja) | 2019-06-28 | 2023-07-03 | 富士フイルム株式会社 | ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環化合物 |
| EP4006045A4 (en) | 2019-08-29 | 2022-10-19 | FUJIFILM Corporation | METHOD FOR PRODUCTION OF A NUCLEIC ACID COMPOUND AND NUCLEIC ACID COMPOUND |
| US20250282813A1 (en) | 2021-04-09 | 2025-09-11 | Bachem Holding Ag | Pseudo solid phase protecting group and methods for the synthesis of oligonucleotides and oligonucleotide conjugates |
| JP7162853B1 (ja) | 2021-07-02 | 2022-10-31 | ペプチスター株式会社 | 液相ペプチド合成用担体結合ペプチドの分析方法 |
| JPWO2024096023A1 (https=) | 2022-11-01 | 2024-05-10 | ||
| WO2024143514A1 (ja) | 2022-12-28 | 2024-07-04 | 中外製薬株式会社 | 環状ペプチドの精製法及び製造法 |
| EP4516392A1 (en) | 2023-09-04 | 2025-03-05 | Vito NV | Peptides, peptidic nucleic acids (pna) and oligonucleotides synthesis assisted by membrane extraction |
| US20250188118A1 (en) | 2023-12-06 | 2025-06-12 | Amgen Inc. | Liquid phase peptide synthesis methods |
| CN119462823B (zh) * | 2024-11-08 | 2025-11-11 | 西北工业大学 | 金团簇纳米酶配体和自组装水凝胶及水凝胶制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4014937A (en) * | 1974-08-26 | 1977-03-29 | Pfizer Inc. | 3,4-And 3,5-dialkoxyphenethylamines |
| JPH06239995A (ja) * | 1993-02-22 | 1994-08-30 | Matsushita Electric Works Ltd | ポリアニリン誘導体およびその製造方法 |
| JP3919227B2 (ja) | 1996-05-02 | 2007-05-23 | テルモ株式会社 | アミジン誘導体及びそれを構成成分とする薬物担体 |
| JP2000044493A (ja) * | 1998-07-27 | 2000-02-15 | Asahi Chem Ind Co Ltd | 化合物ライブラリー合成用保護基 |
| JP2001122889A (ja) | 1999-10-26 | 2001-05-08 | Noguchi Inst | 糖脂質アナログ化合物 |
| US6806357B1 (en) | 2001-08-20 | 2004-10-19 | University Of Pittsburgh | Fluorous nucleophilic substitution of alcohols and reagents for use therein |
| JP4283469B2 (ja) | 2001-12-19 | 2009-06-24 | 独立行政法人科学技術振興機構 | 相溶性−多相有機溶媒システムによりアミノ酸を逐次的に付加する液相ペプチド合成法 |
| WO2003018188A1 (fr) * | 2001-08-24 | 2003-03-06 | Japan Science And Technology Agency | Systeme de solvant multiphase compatible |
| JP2003292494A (ja) | 2002-04-01 | 2003-10-15 | Japan Science & Technology Corp | 温度依存的集合形態を有するデンドリマー及びそれから成る発光体 |
| JP2004059509A (ja) | 2002-07-30 | 2004-02-26 | Nokodai Tlo Kk | 液相ペプチド合成用アミノ酸試薬 |
| CN1753725A (zh) * | 2003-02-24 | 2006-03-29 | 东京农工大学Tlo株式会社 | 使用互溶·分离状态随温度发生可逆变化的溶剂组合的化学处理方法 |
| JP4360854B2 (ja) | 2003-07-08 | 2009-11-11 | テルモ株式会社 | グアニジン誘導体およびそれを構成成分とする薬物担体 |
| JPWO2006104166A1 (ja) | 2005-03-29 | 2008-09-11 | 国立大学法人東京農工大学 | 晶析分離用担体及び化合物の分離方法 |
| ES2546808T3 (es) * | 2006-03-24 | 2015-09-28 | Jitsubo Co., Ltd. | Reactivo para síntesis orgánica y método de reacción de síntesis orgánica con dicho reactivo |
-
2007
- 2007-02-19 ES ES07714522.5T patent/ES2546808T3/es active Active
- 2007-02-19 EP EP07714522.5A patent/EP2003104B1/en active Active
- 2007-02-19 WO PCT/JP2007/052996 patent/WO2007122847A1/ja not_active Ceased
- 2007-02-19 US US12/225,442 patent/US8093435B2/en active Active
- 2007-02-19 DK DK07714522.5T patent/DK2003104T3/en active
- 2007-02-19 AU AU2007242276A patent/AU2007242276A1/en not_active Abandoned
- 2007-02-19 JP JP2008511981A patent/JPWO2007122847A1/ja active Pending
- 2007-02-19 CN CN2007800103222A patent/CN101405240B/zh active Active
-
2009
- 2009-05-18 JP JP2009120386A patent/JP5113118B2/ja active Active
-
2012
- 2012-01-09 US US13/346,175 patent/US8293948B2/en active Active
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