JP2013534911A5 - - Google Patents
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- Publication number
- JP2013534911A5 JP2013534911A5 JP2013512927A JP2013512927A JP2013534911A5 JP 2013534911 A5 JP2013534911 A5 JP 2013534911A5 JP 2013512927 A JP2013512927 A JP 2013512927A JP 2013512927 A JP2013512927 A JP 2013512927A JP 2013534911 A5 JP2013534911 A5 JP 2013534911A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrrolidine
- compound
- formula
- radioactive tracer
- och
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(Cc1c2)C(c3cncc(*)c3*)=Cc1ccc2O* Chemical compound *C(Cc1c2)C(c3cncc(*)c3*)=Cc1ccc2O* 0.000 description 6
- AVFZOVWCLRSYKC-UHFFFAOYSA-N CN1CCCC1 Chemical compound CN1CCCC1 AVFZOVWCLRSYKC-UHFFFAOYSA-N 0.000 description 5
- LNWWQYYLZVZXKS-UHFFFAOYSA-N CC(N1CCCC1)=O Chemical compound CC(N1CCCC1)=O LNWWQYYLZVZXKS-UHFFFAOYSA-N 0.000 description 3
- BROAMUNQJDPCMJ-XETXAFAXSA-N CCC([C@@H](C)OC)/C=N\C(C)=C Chemical compound CCC([C@@H](C)OC)/C=N\C(C)=C BROAMUNQJDPCMJ-XETXAFAXSA-N 0.000 description 2
- SUMNOUVEONJYQD-VGXONPELSA-N C[C@]12[C@]3(C)NCC(COC)[C@@H]1[C@@H]23 Chemical compound C[C@]12[C@]3(C)NCC(COC)[C@@H]1[C@@H]23 SUMNOUVEONJYQD-VGXONPELSA-N 0.000 description 2
- QDUSULRWHFZUHU-BLQKWXTKSA-N CC/C(/C)=C\N=C/CCOC Chemical compound CC/C(/C)=C\N=C/CCOC QDUSULRWHFZUHU-BLQKWXTKSA-N 0.000 description 1
- PJTPIYVGEOIXKX-GLPXXELUSA-N C[C@@H](C(C)(C)C1C2)NC[C@@H]1[C@@]2(C)OC Chemical compound C[C@@H](C(C)(C)C1C2)NC[C@@H]1[C@@]2(C)OC PJTPIYVGEOIXKX-GLPXXELUSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10164663A EP2394668A1 (en) | 2010-06-01 | 2010-06-01 | PET radiopharmaceuticals for differential diagnosis between bilateral and unilateral conditions of primary hyperaldosteronism |
| EP10164663.6 | 2010-06-01 | ||
| PCT/EP2011/059135 WO2011151411A1 (en) | 2010-06-01 | 2011-06-01 | Pet radiopharmaceuticals for differential diagnosis between bilateral and unilateral conditions of primary hyperaldosteronism |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013534911A JP2013534911A (ja) | 2013-09-09 |
| JP2013534911A5 true JP2013534911A5 (https=) | 2014-09-04 |
| JP5851493B2 JP5851493B2 (ja) | 2016-02-03 |
Family
ID=42668720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013512927A Expired - Fee Related JP5851493B2 (ja) | 2010-06-01 | 2011-06-01 | 原発性高アルドステロン症の両側性状態と片側性状態との鑑別診断のためのｐｅｔ放射性医薬 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20130089502A1 (https=) |
| EP (2) | EP2394668A1 (https=) |
| JP (1) | JP5851493B2 (https=) |
| WO (1) | WO2011151411A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2861071B1 (en) * | 2012-04-04 | 2017-03-15 | Merck Sharp & Dohme Corp. | Aldosterone synthase inhibitors |
| JP6048958B2 (ja) * | 2012-12-27 | 2016-12-21 | 日本メジフィジックス株式会社 | 副腎疾患の画像診断剤 |
| JP2015193545A (ja) * | 2014-03-31 | 2015-11-05 | 国立大学法人京都大学 | ２−（３−ピリジニル）−１ｈ−ベンズイミダゾール誘導体化合物、これを含む放射性医薬 |
| ES2821273T3 (es) * | 2014-06-26 | 2021-04-23 | Nihon Mediphysics Co Ltd | Compuesto derivado de 2-(3-piridinil)-1H-bencimidazol y medicamento que lo contiene |
| WO2017213247A1 (ja) | 2016-06-10 | 2017-12-14 | 日本メジフィジックス株式会社 | 心疾患の非侵襲的画像診断剤 |
| EP3357910A1 (en) * | 2017-02-02 | 2018-08-08 | Julius-Maximilians-Universität Würzburg | Compound for in vivo diagnosis of a dysfunction of adrenal glands |
| JP7209970B2 (ja) | 2017-12-28 | 2023-01-23 | 日本メジフィジックス株式会社 | ２－［５－（イミダゾール－１－イルメチル）ピリジン－３－イル］ベンズイミダゾール誘導体化合物、及び、これを含む医薬 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006092430A1 (de) * | 2005-03-03 | 2006-09-08 | Universität des Saarlandes | Selektive hemmstoffe humaner corticoidsynthasen |
| CA2650904C (en) * | 2006-05-02 | 2015-07-07 | The Trustees Of The University Of Pennsylvania | Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents |
| US8519134B2 (en) * | 2009-11-17 | 2013-08-27 | Novartis Ag | Aryl-pyridine derivatives as aldosterone synthase inhibitors |
-
2010
- 2010-06-01 EP EP10164663A patent/EP2394668A1/en not_active Ceased
-
2011
- 2011-06-01 US US13/700,767 patent/US20130089502A1/en not_active Abandoned
- 2011-06-01 JP JP2013512927A patent/JP5851493B2/ja not_active Expired - Fee Related
- 2011-06-01 WO PCT/EP2011/059135 patent/WO2011151411A1/en not_active Ceased
- 2011-06-01 EP EP11723066.4A patent/EP2575899A1/en not_active Withdrawn
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