JP2009185034A5 - - Google Patents
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- Publication number
- JP2009185034A5 JP2009185034A5 JP2009062262A JP2009062262A JP2009185034A5 JP 2009185034 A5 JP2009185034 A5 JP 2009185034A5 JP 2009062262 A JP2009062262 A JP 2009062262A JP 2009062262 A JP2009062262 A JP 2009062262A JP 2009185034 A5 JP2009185034 A5 JP 2009185034A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- independently
- pharmaceutical composition
- composition according
- aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(*)(C(*)(*)N(C1(*)*)*=I)C(*)(CC*)C1(**)*=* Chemical compound CC(*)(C(*)(*)N(C1(*)*)*=I)C(*)(CC*)C1(**)*=* 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4772497P | 1997-05-27 | 1997-05-27 | |
| US60/047,724 | 1997-05-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50081799A Division JP4856294B2 (ja) | 1997-05-27 | 1998-05-27 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013003496A Division JP2013121964A (ja) | 1997-05-27 | 2013-01-11 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009185034A JP2009185034A (ja) | 2009-08-20 |
| JP2009185034A5 true JP2009185034A5 (https=) | 2011-10-06 |
| JP5270413B2 JP5270413B2 (ja) | 2013-08-21 |
Family
ID=21950574
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50081799A Expired - Fee Related JP4856294B2 (ja) | 1997-05-27 | 1998-05-27 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
| JP2009062262A Expired - Fee Related JP5270413B2 (ja) | 1997-05-27 | 2009-03-16 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
| JP2013003496A Pending JP2013121964A (ja) | 1997-05-27 | 2013-01-11 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50081799A Expired - Fee Related JP4856294B2 (ja) | 1997-05-27 | 1998-05-27 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013003496A Pending JP2013121964A (ja) | 1997-05-27 | 2013-01-11 | 癌の予防および治療処置におけるニトロキシドまたはそのプロドラッグの使用 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0986393B1 (https=) |
| JP (3) | JP4856294B2 (https=) |
| AT (1) | ATE262330T1 (https=) |
| AU (1) | AU746505B2 (https=) |
| CA (1) | CA2289017C (https=) |
| DE (1) | DE69822626T8 (https=) |
| DK (1) | DK0986393T3 (https=) |
| ES (1) | ES2216286T3 (https=) |
| PT (1) | PT986393E (https=) |
| WO (1) | WO1998053835A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096759A (en) * | 1997-09-19 | 2000-08-01 | Georgetown University | Method for treating essential hypertension |
| EP1089734A2 (en) * | 1998-06-26 | 2001-04-11 | Georgetown University Medical Center | Use of tempo and tempo derivatives for inducing cell death |
| US20040219201A1 (en) * | 2001-12-06 | 2004-11-04 | Yechezkel Barenholz | Tempamine compositions and methods of use |
| EP1633337A4 (en) * | 2003-05-29 | 2007-09-05 | Mitos Pharmaceuticals Inc | METHODS OF USING NITROXIDES IN CONJUNCTION WITH PHOTOSENSITIZERS AND SENOSENSITIZERS |
| US20120046314A1 (en) * | 2005-02-02 | 2012-02-23 | Mitos, Inc. | Nitroxides for use in treating or preventing neoplastic disease |
| US8466130B2 (en) | 2009-09-04 | 2013-06-18 | Colby Pharmaceutical Company | Mitochondria targeted cationic anti-oxidant compounds for prevention, therapy or treatment of hyper-proliferative disease, neoplasias and cancers |
| EP2139522A2 (en) * | 2007-03-06 | 2010-01-06 | Colby Pharmaceutical Company | Mitochondria targeted cationic anti-oxidant compounds for prevention, therapy or treatment of hyper-proliferative disease, neoplasias and cancers |
| US8853277B2 (en) | 2009-11-30 | 2014-10-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nitroxide therapy for the treatment of von Hippel—Lindau disease (VHL) and renal clear cell carcinoma (RCC) |
| US20180078539A1 (en) | 2016-03-23 | 2018-03-22 | Louis Habash | T-cell regulation in t-cell mediated diseases by reducing pathogenic function of th17 in a human subject through treatment with a nitroxide |
| US10231959B2 (en) | 2016-03-23 | 2019-03-19 | Louis Habash | Increasing expression level of apoptosis-related genes by treating a human subject with a nitroxide |
| JP2019509352A (ja) * | 2016-03-23 | 2019-04-04 | ルイス ハバシュ， | ヒトの被験物質をニトロキシドで処理することによってａｐｏｐｔｏｓｉｓ関連遺伝子の発現レベルを増加させる |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4758580A (en) * | 1985-06-26 | 1988-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts |
| ATE113469T1 (de) * | 1990-06-21 | 1994-11-15 | Edith Dr Huland | Verwendung zytokinhaltiger aerosole und zytokinhaltige aerosole selbst. |
| US6605619B1 (en) * | 1992-03-20 | 2003-08-12 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroxides as protectors against oxidatives stress |
| JPH11500119A (ja) * | 1995-02-16 | 1999-01-06 | エフ・ホフマン−ラ ロシュ アーゲー | インターロイキン１２を用いる脈管形成の阻害 |
-
1998
- 1998-05-27 WO PCT/US1998/010685 patent/WO1998053835A1/en not_active Ceased
- 1998-05-27 PT PT98923772T patent/PT986393E/pt unknown
- 1998-05-27 AU AU75987/98A patent/AU746505B2/en not_active Ceased
- 1998-05-27 DK DK98923772T patent/DK0986393T3/da active
- 1998-05-27 CA CA002289017A patent/CA2289017C/en not_active Expired - Fee Related
- 1998-05-27 EP EP98923772A patent/EP0986393B1/en not_active Expired - Lifetime
- 1998-05-27 JP JP50081799A patent/JP4856294B2/ja not_active Expired - Fee Related
- 1998-05-27 ES ES98923772T patent/ES2216286T3/es not_active Expired - Lifetime
- 1998-05-27 AT AT98923772T patent/ATE262330T1/de active
- 1998-05-27 DE DE69822626T patent/DE69822626T8/de active Active
-
2009
- 2009-03-16 JP JP2009062262A patent/JP5270413B2/ja not_active Expired - Fee Related
-
2013
- 2013-01-11 JP JP2013003496A patent/JP2013121964A/ja active Pending
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