JP2012507521A5 - - Google Patents
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- Publication number
- JP2012507521A5 JP2012507521A5 JP2011534525A JP2011534525A JP2012507521A5 JP 2012507521 A5 JP2012507521 A5 JP 2012507521A5 JP 2011534525 A JP2011534525 A JP 2011534525A JP 2011534525 A JP2011534525 A JP 2011534525A JP 2012507521 A5 JP2012507521 A5 JP 2012507521A5
- Authority
- JP
- Japan
- Prior art keywords
- difficile
- group
- composition
- acyl
- con
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@](CC*)[C@@](CC1)[C@@](C)(CC2)[C@]1[C@@]1[C@]2[C@@](C)(CCC(*)C2)[C@]2CC1* Chemical compound C[C@](CC*)[C@@](CC1)[C@@](C)(CC2)[C@]1[C@@]1[C@]2[C@@](C)(CCC(*)C2)[C@]2CC1* 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11074708P | 2008-11-03 | 2008-11-03 | |
| US61/110,747 | 2008-11-03 | ||
| US12283508P | 2008-12-16 | 2008-12-16 | |
| US61/122,835 | 2008-12-16 | ||
| US15013609P | 2009-02-05 | 2009-02-05 | |
| US61/150,136 | 2009-02-05 | ||
| PCT/US2009/005929 WO2010062369A2 (en) | 2008-11-03 | 2009-11-02 | Methods and compositions for inhibiting clostridium difficile spore germination and outgrowth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507521A JP2012507521A (ja) | 2012-03-29 |
| JP2012507521A5 true JP2012507521A5 (https=) | 2012-12-13 |
| JP5620392B2 JP5620392B2 (ja) | 2014-11-05 |
Family
ID=42226300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011534525A Expired - Fee Related JP5620392B2 (ja) | 2008-11-03 | 2009-11-02 | クロストリジウム・ディフィシレ胞子の発芽および伸長を阻害するための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9340569B2 (https=) |
| EP (1) | EP2367839A4 (https=) |
| JP (1) | JP5620392B2 (https=) |
| AU (1) | AU2009320350B2 (https=) |
| CA (1) | CA2779413A1 (https=) |
| WO (1) | WO2010062369A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9079935B2 (en) | 2012-08-13 | 2015-07-14 | The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas | Reducing risk of contracting Clostridium-difficile associated disease |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| SG11201503966PA (en) | 2012-11-23 | 2015-06-29 | Seres Health Inc | Synergistic bacterial compositions and methods of production and use thereof |
| JP2016509003A (ja) | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| US10973861B2 (en) | 2013-02-04 | 2021-04-13 | Seres Therapeutics, Inc. | Compositions and methods |
| WO2014145958A2 (en) | 2013-03-15 | 2014-09-18 | Seres Health, Inc. | Network-based microbial compositions and methods |
| WO2015076788A1 (en) | 2013-11-19 | 2015-05-28 | The Texas A&M University System | Muricholic acid-based compounds as inhibitors of clostridium difficile spore germination |
| CN105979952B (zh) | 2013-11-25 | 2022-04-08 | 赛里斯治疗公司 | 协同细菌组合物以及其制造方法和用途 |
| US9956282B2 (en) | 2013-12-16 | 2018-05-01 | Seres Therapeutics, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
| US20170087196A1 (en) * | 2014-05-19 | 2017-03-30 | Memorial Sloan-Kettering Cancer Center | Methods and compositions for reducing clostridium difficile infection |
| GB201421071D0 (en) * | 2014-11-27 | 2015-01-14 | Univ Aston | Compound for treating clostridium difficile |
| WO2016127102A2 (en) | 2015-02-06 | 2016-08-11 | Ernesto Abel-Santos | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis |
| CN115252650A (zh) * | 2015-11-03 | 2022-11-01 | 布里格姆及妇女医院股份有限公司 | 用于治疗和/或预防食物变态反应的治疗性微生物群 |
| CA3019732A1 (en) * | 2016-04-05 | 2017-10-12 | Nch Corporation | Nutrient rich germinant composition and spore incubation method |
| EP3668527A1 (en) | 2017-08-14 | 2020-06-24 | Seres Therapeutics, Inc. | Compositions and methods for treating cholestatic disease |
| KR102323783B1 (ko) * | 2017-09-22 | 2021-11-09 | 주식회사 고바이오랩 | 클로스트리디움 디피실레(Clostridium difficile) 성장 억제효과를 갖는 클로스트리디움 신덴스 균주 |
| BR112020008552A2 (pt) | 2017-10-30 | 2020-12-29 | Seres Therapeutics, Inc. | métodos e composições para tratamento de resistência a antibiótico |
| TW202021595A (zh) | 2018-08-10 | 2020-06-16 | 德商菲尼克斯製藥股份有限公司 | 用於預防及治療困難梭狀芽孢桿菌關聯疾病之異石膽酸或異別石膽酸及其氘化衍生物 |
| EP3836947A4 (en) | 2018-08-17 | 2022-04-20 | Universidad Andres Bello | METHOD AND PHARMACOLOGICAL COMPOSITION FOR THE PREVENTION OF RECURRING INFECTIONS CAUSED BY CLOSTRIDIUM DIFFICILE |
| WO2020260558A1 (en) | 2019-06-27 | 2020-12-30 | Phenex Pharmaceuticals Ag | 3-modified iso-/isoallo-lithocholic acid derivatives or their homo-analogs for preventing and treating clostridioides difficile-associated diseases |
| WO2021023100A1 (zh) * | 2019-08-06 | 2021-02-11 | 杜心赟 | 脱氧胆酸类化合物、药物组合物及其用途 |
| CN115279889B (zh) * | 2020-01-16 | 2024-09-10 | 庆应义塾 | 用于生成胆汁酸的组合物 |
| WO2021163212A1 (en) | 2020-02-10 | 2021-08-19 | Native Microbials, Inc. | Microbial compositions and methods of use for canine enteropathy and dysbiosis |
| WO2023039159A2 (en) | 2021-09-09 | 2023-03-16 | Abel Santos Ernesto | Inhibitors of c. difficile spore germination |
| WO2023079335A1 (en) | 2021-11-03 | 2023-05-11 | Universidad Andrés Bello | Composition based on nystatin and vancomycin nanoparticles for the treatment of clostridioides difficile infection and prevention of recurrence |
| WO2023105494A1 (en) | 2021-12-10 | 2023-06-15 | Universidade Do Porto | Cationic steroid compounds, method of obtaining thereof, formulations comprising thereof and their uses |
| CN120905091A (zh) * | 2025-09-30 | 2025-11-07 | 北京常友生物科技有限公司 | 大肠埃希氏菌yc49及其协同拟杆菌在抑制艰难梭菌中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3708510A (en) * | 1970-09-03 | 1973-01-02 | Merck & Co Inc | Amides of cholanic acid,cholenic acid,and choladienic acid |
| JPS62175497A (ja) | 1986-01-28 | 1987-08-01 | Wakunaga Pharmaceut Co Ltd | 胆汁酸誘導体およびその製造法 |
| JPH0749438B2 (ja) * | 1990-10-31 | 1995-05-31 | 東京田辺製薬株式会社 | タウリン抱合型胆汁酸の精製方法 |
| DE19645044A1 (de) * | 1996-10-31 | 1998-05-07 | Falk Pharma Gmbh | Verwendung von Ursodeoxycholsäure zur topischen Behandlung von Entzündungserkrankungen der Schleimhäute |
| IL123998A (en) | 1998-04-08 | 2004-09-27 | Galmed Int Ltd | Conjugates of bile salts and pharmaceutical preparations containing them |
| US6326364B1 (en) * | 1999-02-08 | 2001-12-04 | Cedars-Sinai Medical Center | Use of 5-aminosalicylates as antimicrobial agents |
| US7247299B2 (en) * | 2002-11-27 | 2007-07-24 | Kemin Industries, Inc. | Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens |
| AU2007230991A1 (en) * | 2006-03-22 | 2007-10-04 | Syndexa Pharmaceuticals Corporation | Compounds and methods for treatment of disorders associated with ER stress |
| US20080254010A1 (en) * | 2007-03-12 | 2008-10-16 | Joseph Myron Sasser | Controlling Clostridium difficile-Associated Disease in the Gastrointestinal Tract |
-
2009
- 2009-11-02 JP JP2011534525A patent/JP5620392B2/ja not_active Expired - Fee Related
- 2009-11-02 EP EP09829458A patent/EP2367839A4/en not_active Withdrawn
- 2009-11-02 AU AU2009320350A patent/AU2009320350B2/en not_active Ceased
- 2009-11-02 CA CA2779413A patent/CA2779413A1/en not_active Abandoned
- 2009-11-02 WO PCT/US2009/005929 patent/WO2010062369A2/en not_active Ceased
- 2009-11-02 US US13/126,687 patent/US9340569B2/en not_active Expired - Fee Related
-
2016
- 2016-04-20 US US15/133,437 patent/US20170056419A1/en not_active Abandoned
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