JP2008542225A5 - - Google Patents
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- Publication number
- JP2008542225A5 JP2008542225A5 JP2008512772A JP2008512772A JP2008542225A5 JP 2008542225 A5 JP2008542225 A5 JP 2008542225A5 JP 2008512772 A JP2008512772 A JP 2008512772A JP 2008512772 A JP2008512772 A JP 2008512772A JP 2008542225 A5 JP2008542225 A5 JP 2008542225A5
- Authority
- JP
- Japan
- Prior art keywords
- blue
- dental composition
- indicator
- green
- sodium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 4
- 150000007513 acids Chemical class 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- FRPHFZCDPYBUAU-UHFFFAOYSA-N Bromocresolgreen Chemical compound CC1=C(Br)C(O)=C(Br)C=C1C1(C=2C(=C(Br)C(O)=C(Br)C=2)C)C2=CC=CC=C2S(=O)(=O)O1 FRPHFZCDPYBUAU-UHFFFAOYSA-N 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- NALAHUMLLLSQDP-UHFFFAOYSA-N (2,3,4,5,6-pentamethoxyphenyl)-diphenylmethanol Chemical compound COC1=C(C(=C(C(=C1C(O)(C1=CC=CC=C1)C1=CC=CC=C1)OC)OC)OC)OC NALAHUMLLLSQDP-UHFFFAOYSA-N 0.000 claims 1
- UFBJCMHMOXMLKC-UHFFFAOYSA-N 2,4-dinitrophenol Chemical compound OC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O UFBJCMHMOXMLKC-UHFFFAOYSA-N 0.000 claims 1
- JCYPECIVGRXBMO-UHFFFAOYSA-N 4-(dimethylamino)azobenzene Chemical compound C1=CC(N(C)C)=CC=C1N=NC1=CC=CC=C1 JCYPECIVGRXBMO-UHFFFAOYSA-N 0.000 claims 1
- MGUKYHHAGPFJMC-UHFFFAOYSA-N 4-[3-(4-hydroxy-2,5-dimethylphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]-2,5-dimethylphenol Chemical compound C1=C(O)C(C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C(=CC(O)=C(C)C=2)C)=C1C MGUKYHHAGPFJMC-UHFFFAOYSA-N 0.000 claims 1
- OLQIKGSZDTXODA-UHFFFAOYSA-N 4-[3-(4-hydroxy-2-methylphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]-3-methylphenol Chemical compound CC1=CC(O)=CC=C1C1(C=2C(=CC(O)=CC=2)C)C2=CC=CC=C2S(=O)(=O)O1 OLQIKGSZDTXODA-UHFFFAOYSA-N 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 229960001506 brilliant green Drugs 0.000 claims 1
- HXCILVUBKWANLN-UHFFFAOYSA-N brilliant green cation Chemical group C1=CC(N(CC)CC)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](CC)CC)C=C1 HXCILVUBKWANLN-UHFFFAOYSA-N 0.000 claims 1
- UDSAIICHUKSCKT-UHFFFAOYSA-N bromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C2=CC=CC=C2S(=O)(=O)O1 UDSAIICHUKSCKT-UHFFFAOYSA-N 0.000 claims 1
- -1 bromophenol blue Sodium salt Chemical class 0.000 claims 1
- IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 claims 1
- OBRMNDMBJQTZHV-UHFFFAOYSA-N cresol red Chemical compound C1=C(O)C(C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C=C(C)C(O)=CC=2)=C1 OBRMNDMBJQTZHV-UHFFFAOYSA-N 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- ZXJXZNDDNMQXFV-UHFFFAOYSA-M crystal violet Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1[C+](C=1C=CC(=CC=1)N(C)C)C1=CC=C(N(C)C)C=C1 ZXJXZNDDNMQXFV-UHFFFAOYSA-M 0.000 claims 1
- 208000002925 dental caries Diseases 0.000 claims 1
- OOYIOIOOWUGAHD-UHFFFAOYSA-L disodium;2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate Chemical compound [Na+].[Na+].O1C(=O)C(C(=C(Cl)C(Cl)=C2Cl)Cl)=C2C21C1=CC(Br)=C([O-])C(Br)=C1OC1=C(Br)C([O-])=C(Br)C=C21 OOYIOIOOWUGAHD-UHFFFAOYSA-L 0.000 claims 1
- YQGOJNYOYNNSMM-UHFFFAOYSA-N eosin Chemical compound [Na+].OC(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C(O)=C(Br)C=C21 YQGOJNYOYNNSMM-UHFFFAOYSA-N 0.000 claims 1
- IINNWAYUJNWZRM-UHFFFAOYSA-L erythrosin B Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(I)C(=O)C(I)=C2OC2=C(I)C([O-])=C(I)C=C21 IINNWAYUJNWZRM-UHFFFAOYSA-L 0.000 claims 1
- 229940011411 erythrosine Drugs 0.000 claims 1
- 235000012732 erythrosine Nutrition 0.000 claims 1
- 239000004174 erythrosine Substances 0.000 claims 1
- DWCZIOOZPIDHAB-UHFFFAOYSA-L methyl green Chemical compound [Cl-].[Cl-].C1=CC(N(C)C)=CC=C1C(C=1C=CC(=CC=1)[N+](C)(C)C)=C1C=CC(=[N+](C)C)C=C1 DWCZIOOZPIDHAB-UHFFFAOYSA-L 0.000 claims 1
- STZCRXQWRGQSJD-GEEYTBSJSA-M methyl orange Chemical compound [Na+].C1=CC(N(C)C)=CC=C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 STZCRXQWRGQSJD-GEEYTBSJSA-M 0.000 claims 1
- 229940012189 methyl orange Drugs 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- BAVBEHWEOJMHDS-UHFFFAOYSA-M sodium;4-[3-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]-5-methyl-2-propan-2-ylphenolate Chemical compound [Na+].C1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C(=CC([O-])=C(C(C)C)C=2)C)=C1C BAVBEHWEOJMHDS-UHFFFAOYSA-M 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- PRZSXZWFJHEZBJ-UHFFFAOYSA-N thymol blue Chemical compound C1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C(=CC(O)=C(C(C)C)C=2)C)=C1C PRZSXZWFJHEZBJ-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05011336A EP1733762A1 (en) | 2005-05-25 | 2005-05-25 | Dental composition for detection of carious tissue, detection method |
| EP05011336.4 | 2005-05-25 | ||
| PCT/EP2006/005004 WO2006125650A1 (en) | 2005-05-25 | 2006-05-24 | Dental composition for detection of carious tissue, detection method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008542225A JP2008542225A (ja) | 2008-11-27 |
| JP2008542225A5 true JP2008542225A5 (enExample) | 2009-07-09 |
| JP5054002B2 JP5054002B2 (ja) | 2012-10-24 |
Family
ID=35735006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512772A Expired - Fee Related JP5054002B2 (ja) | 2005-05-25 | 2006-05-24 | 齲蝕組織を検出する歯科用組成物、検出方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20080241800A1 (enExample) |
| EP (2) | EP1733762A1 (enExample) |
| JP (1) | JP5054002B2 (enExample) |
| KR (1) | KR101260542B1 (enExample) |
| CN (1) | CN101184533B (enExample) |
| AU (1) | AU2006251265B2 (enExample) |
| CA (1) | CA2609044A1 (enExample) |
| WO (1) | WO2006125650A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5366553B2 (ja) | 2005-11-09 | 2013-12-11 | クロックス テクノロジーズ インコーポレイテッド | 歯のホワイトニング組成物及び方法 |
| US8647119B1 (en) | 2006-04-18 | 2014-02-11 | President And Fellows Of Harvard College | Methods and kits with fluorescent probes for caries detection |
| US20100266989A1 (en) | 2006-11-09 | 2010-10-21 | Klox Technologies Inc. | Teeth whitening compositions and methods |
| JP5005373B2 (ja) * | 2007-02-02 | 2012-08-22 | 株式会社ジーシー | 齲蝕活性評価用の歯垢染色用組成物 |
| CA2706355C (en) * | 2008-02-08 | 2014-11-18 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| WO2010062377A2 (en) | 2008-10-31 | 2010-06-03 | Yale University | Methods and compositions for the detection and treatment of preeclampsia |
| NZ592651A (en) | 2008-11-07 | 2013-05-31 | Klox Technologies Inc | Oxidatitive photoactivated skin rejeuvenation composition comprising hyaluronic acid, glucosamine, or allantoin |
| GB0909206D0 (en) | 2009-05-28 | 2009-07-15 | Lux Innovate Ltd | Approximal imaging device |
| PL2453922T3 (pl) | 2009-07-17 | 2018-03-30 | Klox Technologies Inc. | Przeciwbakteryjna doustna kompozycja |
| US20130281913A1 (en) | 2012-04-20 | 2013-10-24 | Klox Technologies Inc. | Biophotonic compositions and methods for providing biophotonic treatment |
| US11116841B2 (en) | 2012-04-20 | 2021-09-14 | Klox Technologies Inc. | Biophotonic compositions, kits and methods |
| EP2895139B1 (en) | 2012-09-14 | 2019-10-23 | Bausch Health Companies Inc. | Methods for teeth whitening |
| EP2925275A2 (en) * | 2012-11-30 | 2015-10-07 | Rls Global Ab | Detection of carious dentin tissue and removal thereof by means of a dental instrument |
| US20140276354A1 (en) | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
| HK1219890A1 (zh) | 2013-07-03 | 2017-04-21 | 广东科洛克生物医药集团有限公司 | 治疗不癒合伤口的组合物和方法 |
| JP2017509433A (ja) | 2014-04-01 | 2017-04-06 | クロックス テクノロジーズ インコーポレイテッドKlox Technologies Inc. | 組織充填剤組成物および使用方法 |
| CA3157573C (en) * | 2014-04-10 | 2025-11-18 | Yale University | METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS |
| RU2017117187A (ru) | 2014-10-31 | 2018-11-30 | Клокс Текнолоджиз Инк. | Фотоактивируемые волокна и тканые материалы |
| EP3658068B1 (en) * | 2017-07-25 | 2025-04-09 | Solventum Intellectual Properties Company | Water-resistant polymer-based dental articles |
| CN109987969B (zh) * | 2019-04-29 | 2021-07-06 | 成都贝施美生物科技有限公司 | 一种快速浸泡氧化锆义齿染色液 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4167587A (en) * | 1977-06-22 | 1979-09-11 | Danforth Richard C | Compositions and process for colored liquid food or drink |
| JPS57175129A (en) * | 1981-04-19 | 1982-10-28 | Kyoto Daiichi Kagaku:Kk | Composition for testing carious activity |
| US4980152A (en) * | 1987-08-06 | 1990-12-25 | Marion Laboratories | Oral preparation |
| US5154917A (en) * | 1990-09-11 | 1992-10-13 | Beecham Inc. | Color change mouthrinse |
| GB2250817A (en) * | 1990-12-12 | 1992-06-17 | Naresh Gathani | Dental caries diagnostic floss. |
| US5766012A (en) * | 1997-04-28 | 1998-06-16 | Rosenbaum; Michael | Dental etchant and process of using |
| SE514784C2 (sv) * | 1998-08-17 | 2001-04-23 | Mediteam Dental Ab | Metod och preparat för rengöring av rotytor och omgivande vävnader hos tänder |
| JP2002187857A (ja) * | 2000-12-20 | 2002-07-05 | Gc Corp | 初期齲蝕検知材 |
| JP2002323493A (ja) * | 2001-04-27 | 2002-11-08 | Gc Corp | 唾液緩衝能検査方法及び唾液緩衝能検査用具 |
| JP2004205210A (ja) * | 2001-12-14 | 2004-07-22 | Gc Corp | 齲蝕活性評価キット及び齲蝕活性評価用具 |
| US20030113266A1 (en) * | 2001-12-14 | 2003-06-19 | Gc Corporation | Material for evaluating dental caries activity |
-
2005
- 2005-05-25 EP EP05011336A patent/EP1733762A1/en not_active Withdrawn
-
2006
- 2006-05-24 CA CA002609044A patent/CA2609044A1/en not_active Abandoned
- 2006-05-24 KR KR1020077027268A patent/KR101260542B1/ko not_active Expired - Fee Related
- 2006-05-24 WO PCT/EP2006/005004 patent/WO2006125650A1/en not_active Ceased
- 2006-05-24 AU AU2006251265A patent/AU2006251265B2/en not_active Ceased
- 2006-05-24 CN CN200680018215XA patent/CN101184533B/zh not_active Expired - Fee Related
- 2006-05-24 EP EP06753873.6A patent/EP1885456B1/en not_active Not-in-force
- 2006-05-24 JP JP2008512772A patent/JP5054002B2/ja not_active Expired - Fee Related
- 2006-05-24 US US11/914,990 patent/US20080241800A1/en not_active Abandoned
-
2012
- 2012-01-11 US US13/348,310 patent/US20120107245A1/en not_active Abandoned
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