CY1110985T1 - Στοματικες συνθεσεις για απορροφηση των ενωσεων φωσφορου - Google Patents

Στοματικες συνθεσεις για απορροφηση των ενωσεων φωσφορου

Info

Publication number
CY1110985T1
CY1110985T1 CY20101101144T CY101101144T CY1110985T1 CY 1110985 T1 CY1110985 T1 CY 1110985T1 CY 20101101144 T CY20101101144 T CY 20101101144T CY 101101144 T CY101101144 T CY 101101144T CY 1110985 T1 CY1110985 T1 CY 1110985T1
Authority
CY
Cyprus
Prior art keywords
phosphorus compounds
absorption
oral compositions
present
hyperphosphatemia
Prior art date
Application number
CY20101101144T
Other languages
English (en)
Inventor
Vincenzo Savica
Original Assignee
Cm&D Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36035790&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110985(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cm&D Pharma Limited filed Critical Cm&D Pharma Limited
Publication of CY1110985T1 publication Critical patent/CY1110985T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/244Lanthanides; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει φάρμακα χρήσιμα για τη μείωση του επιπέδου φωσφόρου στον ορό, ιδιαίτερα σε εκείνα τα άτομα προσβεβλημένα με υπερφωσφαταιμία. Πιο συγκεκριμένα, η παρούσα εφεύρεση αναφέρεται σε φαρμακευτικές συνθέσεις προς χορήγηση από τη στοματική οδό σε περιόδους νηστείας, προκειμένου να απορροφήσουν τις ενώσεις φωσφόρου από τα ρευστά του εντερικού σωλήνα, ειδικά από το σάλιο.
CY20101101144T 2004-12-07 2010-12-10 Στοματικες συνθεσεις για απορροφηση των ενωσεων φωσφορου CY1110985T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000015A ITME20040015A1 (it) 2004-12-07 2004-12-07 Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
EP05810997A EP1827386B1 (en) 2004-12-07 2005-11-29 Oral compositions for absorption of phosphorus compounds

Publications (1)

Publication Number Publication Date
CY1110985T1 true CY1110985T1 (el) 2015-06-11

Family

ID=36035790

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101101144T CY1110985T1 (el) 2004-12-07 2010-12-10 Στοματικες συνθεσεις για απορροφηση των ενωσεων φωσφορου

Country Status (21)

Country Link
US (4) US7815898B2 (el)
EP (1) EP1827386B1 (el)
JP (1) JP5049135B2 (el)
KR (1) KR101283820B1 (el)
CN (1) CN101068535A (el)
AT (1) ATE481091T1 (el)
BR (1) BRPI0518517A2 (el)
CA (1) CA2587924C (el)
CY (1) CY1110985T1 (el)
DE (1) DE602005023648D1 (el)
DK (1) DK1827386T3 (el)
ES (1) ES2352957T3 (el)
HR (1) HRP20100653T1 (el)
IT (1) ITME20040015A1 (el)
MX (1) MX2007006704A (el)
PL (1) PL1827386T3 (el)
PT (1) PT1827386E (el)
RS (1) RS51507B (el)
RU (1) RU2392926C2 (el)
SI (1) SI1827386T1 (el)
WO (1) WO2006061336A2 (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
CA2620406A1 (en) 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
ITRM20060204A1 (it) * 2006-04-10 2007-10-11 Vincenzo Savica Farmaci e alimentei per diete normoproteiche iperproteiche ipopro teiche tutte ipofosforiche e bevande ipofosforiche
JP2009542653A (ja) * 2006-07-05 2009-12-03 ジェンザイム コーポレーション リン酸塩過剰血症のための鉄(ii)含有治療剤
US7943597B2 (en) 2008-04-08 2011-05-17 Cypress Pharmaceutical, Inc. Phosphate-binding chitosan and uses thereof
AU2008354325A1 (en) * 2008-04-08 2009-10-15 Cypress Pharmaceutical, Inc. Phosphate-binding chitosan and uses thereof
US8877907B2 (en) 2010-06-07 2014-11-04 The Johns Hopkins University Molecularly imprinted polymers
US9314523B2 (en) 2010-09-21 2016-04-19 Elwha Llc Ingestible salt grabber
EP2441436A1 (de) * 2010-10-13 2012-04-18 Fresenius Medical Care Deutschland GmbH Phosphatbinderformulierung zur einfachen Einnahme
US9402808B2 (en) 2011-01-19 2016-08-02 Panacea Biotec Limited Liquid oral composition of lanthanum salts
EP2699099A1 (en) * 2011-04-20 2014-02-26 Gumlink A/S Chewing gum comprising chitosan for use in reduction of the level of free phosphorus compounds in the digestive juice
WO2012143008A1 (en) 2011-04-20 2012-10-26 Gumlink A/S Reduction of the level of free phosphorus compounds in the digestive juice
ES2607986T3 (es) * 2011-06-08 2017-04-05 Kai Pharmaceuticals, Inc. Agentes terapéuticos para regular el fósforo en suero
WO2014039477A1 (en) * 2012-09-04 2014-03-13 The Board Of Regents Of The University Of Texas System Citrate-rich calcium-magnesium supplement and uses thereof
WO2014166545A1 (en) 2013-04-12 2014-10-16 Cm&D Pharma Ltd Compositions comprising a mixture of elastomers and chitosan and use thereof for treating disorders of phosphorous mineral metabolism
EP3287133B1 (en) 2013-06-05 2019-04-17 Tricida Inc. Proton-binding polymers for oral administration
EP2818176A1 (en) 2013-06-27 2014-12-31 Virbac Composition for the treatment of progressive renal diseases
CN103536977A (zh) * 2013-11-04 2014-01-29 于杰 血液灌流器
US9744128B2 (en) 2014-06-05 2017-08-29 Mastix LLC Method for manufacturing medicated chewing gum without cooling
JP6903576B2 (ja) 2014-12-10 2021-07-14 トリシダ・インコーポレイテッドTricida, Inc. 経口投与用プロトン結合ポリマー
CN109414453B (zh) 2016-05-06 2023-02-17 特里赛达公司 用于治疗酸碱失衡的组合物
US10765658B2 (en) 2016-06-22 2020-09-08 Mastix LLC Oral compositions delivering therapeutically effective amounts of cannabinoids
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
TW201940175A (zh) * 2017-11-29 2019-10-16 世展科技股份有限公司 磷結合方法
US11273123B2 (en) 2018-07-18 2022-03-15 USpharma Ltd Chewable pharmaceutical dosage forms
CN109528764B (zh) * 2018-09-30 2021-04-06 北京市中关村医院 一种凝胶基层状无机物磷结合剂及其制备方法和用途

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818807A (en) * 1972-12-06 1974-06-25 Eng Concrete Placer Inc Slurry pump piston seal
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4163777A (en) 1977-04-29 1979-08-07 Lewis/Howe Company Controlled antacid delivery form and method of treatment therewith
US4163177A (en) * 1977-10-17 1979-07-31 Ward Derrick A Oscillation generator providing oscillations of varying amplitude
US4160820A (en) * 1977-11-28 1979-07-10 General Mills, Inc. Plaque inhibiting composition and method
US4515769A (en) * 1981-12-01 1985-05-07 Borden, Inc. Encapsulated flavorant material, method for its preparation, and food and other compositions incorporating same
US4386106A (en) * 1981-12-01 1983-05-31 Borden, Inc. Process for preparing a time delayed release flavorant and an improved flavored chewing gum composition
US4512968A (en) * 1982-11-30 1985-04-23 Lion Corporation Oral compositions
EP0187703B1 (en) * 1985-01-11 1992-08-05 Teijin Limited Sustained release preparation
JPS61161216A (ja) * 1985-01-11 1986-07-21 Teijin Ltd キトサン類を用いた徐放性医薬品組成物
JPS62132830A (ja) * 1985-12-05 1987-06-16 Teijin Ltd 徐放性医薬品組成物
JPS63310833A (ja) * 1987-06-10 1988-12-19 Nippon Medical Supply Corp リン吸着カプセル
DE3936319C3 (de) * 1989-11-01 1997-05-07 Bartz Volker Phosphatbinder zur oralen Verabreichung
US5030459A (en) * 1989-11-07 1991-07-09 Warner-Lambert Company High impact mint flavor for high base chewing gum
JP2884124B2 (ja) * 1992-01-31 1999-04-19 鈴与株式会社 リン吸着剤
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
GB9506126D0 (en) * 1995-03-25 1995-05-10 Johnson Matthey Plc Pharmaceutical composition and method
ES2162658T3 (es) * 1996-03-05 2002-01-01 Mitsubishi Chem Corp Utilizacion de resinas intercambiadoras anionicas para la fabricacion de un medicamento destinado al tratamiento de la hiperfosfatemia.
IE980990A1 (en) * 1998-11-27 2000-05-31 Fuisz Internat Ltd Composition and Method for Medicated Chewing Gum Delivery System
DE19917705C1 (de) 1999-04-20 2000-12-28 Vitasyn Gmbh Mittel zur Therapie von Hyperphosphatämie
US6645535B2 (en) * 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
FI121528B (fi) * 2000-10-30 2010-12-31 Biohit Oyj Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa
US20030072841A1 (en) * 2001-03-19 2003-04-17 The Procter & Gamble Campany Polybutene containing chewing gum and confection
ITMI20012320A1 (it) * 2001-11-06 2003-05-06 Perfetti Van Melle Spa Composizioni orali solide anti-tartaro e anti-placca batterica, utilicome coadiuvanti nell'igiene odonto-stomatologica
IL162823A0 (en) * 2002-01-03 2005-11-20 Yissum Res Dev Co Edible compositions capable of removing oral biofilm
US7244455B2 (en) * 2002-01-16 2007-07-17 Warner-Lambert Company Center-filled chewing gum containing a deliverable form of calcium
SE0302947D0 (sv) * 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
EP2792363B1 (en) * 2003-08-26 2016-06-29 Shire Biopharmaceuticals Holdings Ireland Limited Pharmaceutical formulation comprising lanthanum compounds
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
US8323683B2 (en) * 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
US20070207206A1 (en) * 2006-03-02 2007-09-06 Rice Bronwyn C Chewable pain formula

Also Published As

Publication number Publication date
BRPI0518517A2 (pt) 2008-11-25
RS51507B (en) 2011-06-30
ITME20040015A1 (it) 2005-03-07
CN101068535A (zh) 2007-11-07
US20100316578A1 (en) 2010-12-16
WO2006061336A2 (en) 2006-06-15
ES2352957T3 (es) 2011-02-24
WO2006061336A3 (en) 2006-09-14
US20080125394A1 (en) 2008-05-29
EP1827386B1 (en) 2010-09-15
PT1827386E (pt) 2010-12-03
ATE481091T1 (de) 2010-10-15
HRP20100653T1 (hr) 2011-01-31
CA2587924C (en) 2013-08-20
US20110002858A1 (en) 2011-01-06
SI1827386T1 (sl) 2011-01-31
US20140356297A1 (en) 2014-12-04
US7815898B2 (en) 2010-10-19
RU2392926C2 (ru) 2010-06-27
PL1827386T3 (pl) 2011-05-31
DK1827386T3 (da) 2011-07-11
EP1827386A2 (en) 2007-09-05
KR20070090904A (ko) 2007-09-06
JP2008523022A (ja) 2008-07-03
MX2007006704A (es) 2008-01-16
RU2007125702A (ru) 2009-01-20
KR101283820B1 (ko) 2013-07-15
DE602005023648D1 (de) 2010-10-28
US8518379B2 (en) 2013-08-27
CA2587924A1 (en) 2006-06-15
JP5049135B2 (ja) 2012-10-17

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