JP2008540043A - 磁気刺激装置における強磁性流体による冷却および騒音軽減 - Google Patents
磁気刺激装置における強磁性流体による冷却および騒音軽減 Download PDFInfo
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- A61N2/004—Magnetotherapy specially adapted for a specific therapy
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Abstract
【選択図】 図3
Description
当業者には周知のように、導体に誘導される電場の大きさは、その導体を横切る磁束密度の変化率に比例する。電場が導体中に誘導されると、この電場に対応する電流が導体内に生じる。この電流は、任意の時点における電場のベクトルと同方向に流れる。ピーク電場は磁束密度の経時的変化率が最大のときに起こり、その他の時間ではそれより小さくなる。磁気パルスの適用中、電流は磁場を維持存する方向に流れる(レンツの法則)。
強磁性コアは、磁気装置に連結して磁場を生成するために使用することができる。一部の実施形態において、そのような磁場は、例えば経頭蓋磁気刺激(Transcranial Magnetic Stimulation:TMS)、反復経頭蓋磁気刺激(Repetitive TMS:rTMS)、磁気発作治療(Magnetic Seizure Therapy:MST)、末梢神経の不快感を軽減するなどの経皮的磁気刺激を実施することが目的である可能性がある。上述したように、以下の例でも説明および明瞭化のためTMSおよびrTMSの実施形態に関連して説明しているが、上記のタイプ全てを含め、いかなるタイプの経皮的磁性刺激も、本発明の一実施形態に従った実施が可能である。また上記でも説明したが、本発明の実施形態は経皮的磁気刺激に限定されるものではなく、一実施形態は、いかなる目的で磁場を生成する磁気装置に関しても使用することができる。
一般に、強磁性流体は、例えば約10nmサイズの小さい磁性粒子の懸濁液である。このような小粒子サイズを選択することにより、前記強磁性流体が使用される用途において適切な時間の間、それらの粒子の沈殿が起こらないことを確実にする。また、1若しくはそれ以上の界面活性剤を使用して油や水などの流体中で磁性粒子の懸濁を確実に維持する場合もある。外部磁場がない場合、前記強磁性流体内の個々の粒子の磁気モーメントは互いに整列していない状態にある。そこに磁場を印加すると、磁気モーメントは印加磁場に配列する。この配列の特性は、前記流体が個々の磁性粒子サイズの磁気モーメントにより常磁性の動作を示すことから、「超常磁性」と呼ばれることが多い。
Claims (51)
- 経皮的磁気刺激装置であって、
十分な強度の磁場を生成して生体組織を刺激するためのコイルと、
前記コイルに連結され且つ当該コイルを実質的に取り囲むチャンバーであって、前記磁場に曝されると磁気対流が生じる強磁性流体を含むものである、前記チャンバーと、
前記チャンバーに連結されて前記強磁性流体を冷却するための熱交換部と
を有する経皮的磁気刺激装置。 - 請求項1記載の装置において、前記チャンバーは、前記コイルと前記熱交換部との間で前記強磁性流体の熱対流および磁気対流を促進するよう構成されているものである。
- 請求項1記載の装置において、前記熱交換部はヒートシンクである。
- 請求項1記載の装置において、前記コイルは強磁性コアを有するものである。
- 請求項1記載の装置において、前記コイルは空芯を有するものである。
- 請求項1記載の装置において、当該装置は、経頭蓋磁気刺激または磁気発作治療に関連してヒトの脳組織を刺激するものである。
- 請求項1記載の装置において、前記チャンバーは前記コイルを実質的に取り囲んで、当該コイルの騒音発生領域を実質的に包囲するものである。
- 請求項7記載の装置において、前記強磁性流体は剪断音波の伝達を妨げるものである。
- 請求項7記載の装置において、前記チャンバー内に含まれる前記強磁性流体および前記磁気装置は第1の騒音減衰接触面を形成するものである。
- 請求項7記載の装置において、前記チャンバー内に含まれる前記強磁性流体および前記熱交換部は第2の騒音減衰接触面を形成するものである。
- 請求項1記載の装置において、前記磁場は第1の磁場であり、この装置は第2の磁場を生成する永久磁石をさらに有し、前記強磁性流体は前記第2の磁場に曝されると磁気対流を生じるものである。
- 請求項1記載の装置において、この装置は、さらに、
前記コイルと前記熱交換部との間で前記強磁性流体を循環させるポンプ機構を有するものである。 - 請求項12記載の装置において、前記ポンプ機構は、前記磁場の存在下でパルス磁場により作動して前記強磁性流体を第1の方向に循環させるものである。
- 請求項13記載の装置において、この装置は、さらに、
前記強磁性流体が第2の方向に循環するのを防ぐバルブを有するものである。 - 強磁性流体チャンバーであって、
生体組織を刺激する上で十分な強度の磁場を生成する構成材に連結されるようなっているハウジングと、
前記構成材を冷却するために前記ハウジング内に提供された強磁性流体と
を有する強磁性流体チャンバー。 - 請求項15記載のチャンバーにおいて、前記ハウジングは、さらに、前記磁場の存在下で前記強磁性流体の対流を可能にするようなっているものである。
- 請求項15記載のチャンバーにおいて、前記ハウジングは、前記構成材の騒音発生領域を実質的に包囲するよう前記構成材の周囲に設けられているものである。
- 請求項15記載のチャンバーにおいて、当該チャンバー内に含まれる前記強磁性流体および前記構成材は第1の騒音減衰接触面を形成するものである。
- 請求項15記載のチャンバーにおいて、前記強磁性流体は剪断音波の伝達を妨げるものである。
- 請求項15記載のチャンバーにおいて、このチャンバーは、さらに、
前記強磁性流体を冷却するための前記ハウジングに連結された熱交換部を有するものである。 - 請求項20記載のチャンバーにおいて、前記熱交換部はヒートシンクである。
- 請求項20記載のチャンバーにおいて、前記ハウジングは、前記コイルと前記熱交換部との間で前記強磁性流体の熱対流および磁気対流を促進するよう構成されているものである。
- 請求項20記載のチャンバーにおいて、前記熱交換部はヒートシンクである。
- 請求項20記載のチャンバーにおいて、前記チャンバー内に含まれる前記強磁性流体および前記熱交換部は第2の騒音減衰接触面を形成するものである。
- 請求項15記載のチャンバーにおいて、前記構成材はコイルである。
- 請求項25記載のチャンバーにおいて、前記コイルは強磁性コアを有するものである。
- 請求項25記載のチャンバーにおいて、前記コイルは空芯を有するものである。
- 請求項15記載のチャンバーにおいて、前記構成材は経頭蓋磁気刺激または磁気発作治療に関連してヒトの脳組織を刺激するものである。
- 請求項15記載のチャンバーにおいて、前記磁場は第1の磁場であり、このチャンバーは前記ハウジングに近接して第2の磁場を生成する永久磁石をさらに有し、前記強磁性流体は前記第2の磁場に曝されると磁気対流を生じるものである。
- 請求項15記載のチャンバーにおいて、このチャンバーは、さらに、前記コイルと前記熱交換部との間で前記強磁性流体を循環させるポンプ機構を有するものである。
- 請求項30記載のチャンバーにおいて、前記ポンプ機構は、磁場の存在下で前記循環を生じさせる磁性材料である。
- 生体組織を刺激する上で十分な強度を有した磁場を生成する磁気刺激システムであって、
前記磁場を生成する構成材と、
実質的に前記構成材の周囲に設けられたチャンバーと、
前記チャンバー内に含まれる強磁性流体と
を有する磁気刺激システム。 - 請求項32記載のシステムにおいて、このシステムは、さらに、
前記強磁性流体を冷却するための熱交換部を有するものである。 - 請求項33記載のシステムにおいて、前記熱交換部はヒートシンクである。
- 請求項33記載のシステムにおいて、前記チャンバーは、前記コイルと前記熱交換部との間で前記強磁性流体の熱対流および磁気対流を促進するよう構成されているものである。
- 請求項35記載のシステムにおいて、前記構成材により生成される前記磁場は、前記強磁性流体の磁気対流を駆動するものである。
- 請求項32記載のシステムにおいて、前記チャンバーは前記構成材の周囲に設けられ、当該構成材の騒音発生領域を実質的に包囲するものである。
- 請求項37記載のシステムにおいて、前記強磁性流体は剪断音波の伝達を妨げるものである。
- 請求項37記載のシステムにおいて、前記チャンバー内に含まれる前記強磁性流体および前記磁気装置は第1の騒音減衰接触面を形成するものである。
- 請求項32記載のシステムにおいて、前記構成材はコイルである。
- 請求項40記載のシステムにおいて、前記コイルは強磁性コアを有する。
- 請求項40記載のシステムにおいて、前記コイルは空芯を有する。
- 請求項32記載のシステムにおいて、前記構成材は、経頭蓋磁気刺激または磁気発作治療に関連して組織を刺激するために使用されるものである。
- 請求項32記載のシステムにおいて、このシステムは、さらに、
前記磁場の存在下で前記強磁性流体を第1の方向に循環させる磁性材料を有するものである。 - 請求項44記載のシステムにおいて、この装置は、さらに、
前記強磁性流体が第2の方向に循環するのを防ぐバルブを有するものである。 - 請求項32記載のシステムにおいて、前記熱交換部はヒートシンクである。
- 磁気装置を冷却する方法であって、
生体組織を刺激する上で十分な強度の磁場を前記磁気装置で生成する工程と、
前記磁場で対流を誘導することにより強磁性流体を循環させる工程と
を有する方法。 - 請求項46記載の方法において、前記対流は前記磁気装置と熱交換部との間で生じ、当該方法は、さらに、
前記熱交換部で前記強磁性流体を冷却する工程を有するものである。 - 請求項46記載の方法において、前記生体組織はヒトの脳組織である。
- 請求項46記載の方法において、前記誘導される強磁性流体の対流は磁気対流および熱対流である。
- 請求項46記載の方法において、この方法は、さらに、
永久磁石で第2の磁場を生成する工程と、当該第2の磁場で前記強磁性流体を循環させる工程とを有するものである。
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