JP2008536865A - 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk - Google Patents

抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk Download PDF

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JP2008536865A
JP2008536865A JP2008506765A JP2008506765A JP2008536865A JP 2008536865 A JP2008536865 A JP 2008536865A JP 2008506765 A JP2008506765 A JP 2008506765A JP 2008506765 A JP2008506765 A JP 2008506765A JP 2008536865 A JP2008536865 A JP 2008536865A
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vitamin
egfr
skin
analog
therapy
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JP2008536865A5 (enExample
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リング,イー−ヘー
ペレズ−ソラー,ロマン
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アルバート・アインシユタイン・カレツジ・オブ・メデイシン・オブ・イエシバ・ユニバーシテイ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008506765A 2005-04-15 2006-04-12 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk Withdrawn JP2008536865A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67156305P 2005-04-15 2005-04-15
PCT/US2006/014158 WO2006113479A2 (en) 2005-04-15 2006-04-12 Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy

Related Child Applications (1)

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JP2012196249A Division JP5620443B2 (ja) 2005-04-15 2012-09-06 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk

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JP2008536865A true JP2008536865A (ja) 2008-09-11
JP2008536865A5 JP2008536865A5 (enExample) 2009-05-28

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JP2008506765A Withdrawn JP2008536865A (ja) 2005-04-15 2006-04-12 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk
JP2012196249A Expired - Fee Related JP5620443B2 (ja) 2005-04-15 2012-09-06 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk

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US (4) US7745494B2 (enExample)
EP (3) EP2494965A3 (enExample)
JP (2) JP2008536865A (enExample)
KR (1) KR101332869B1 (enExample)
AT (1) ATE492275T1 (enExample)
AU (1) AU2006236633B2 (enExample)
CA (2) CA2851079A1 (enExample)
CY (1) CY1111786T1 (enExample)
DE (1) DE602006019074D1 (enExample)
DK (1) DK1871353T3 (enExample)
ES (1) ES2358528T3 (enExample)
PT (1) PT1871353E (enExample)
WO (1) WO2006113479A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012236857A (ja) * 2005-04-15 2012-12-06 Albert Einstein College Of Medicine Of Yeshiva Univ 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk
JP2023132190A (ja) * 2022-03-10 2023-09-22 学校法人福岡大学 ケモカインccl5発現抑制剤

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US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
US9428582B2 (en) * 2006-07-03 2016-08-30 Genmab A/S Method of treating rash in patients undergoing anti-EGFR therapy
US8815953B2 (en) * 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
US20100010100A1 (en) * 2008-07-09 2010-01-14 Hinman Andrew W Dermatological compositions with anti-aging and skin even-toning properties
WO2010014361A1 (en) * 2008-07-30 2010-02-04 Edison Pharmaceuticals, Inc. Naphthoquinone compositions with anti-aging, anti- inflammatory and skin even-toning properties
WO2010048330A1 (en) 2008-10-21 2010-04-29 Threshold Pharmaceuticals, Inc. Treatment of cancer using hypoxia activated prodrugs
EP2445533B1 (en) * 2009-06-26 2017-02-08 Sunny Pharmtech Inc., Method for treating or ameliorating mucocutaneous or ocular toxicities
ITPD20100090A1 (it) * 2010-03-22 2011-09-23 Sanitas Farmaceutici S R L Formulazione topica per il trattamento di eruzioni cutanee, in particolare conseguenti a trattamenti con farmaci anti egfr
JP5062922B2 (ja) 2011-02-14 2012-10-31 株式会社J−オイルミルズ 皮膚コラーゲン産生促進剤
EP2712613B1 (en) * 2012-09-28 2017-02-08 Pharmadab d.o.o. Vitamin K1 and uses thereof
US9421297B2 (en) 2014-04-02 2016-08-23 Adhezion Biomedical, Llc Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides
EP3250180B1 (en) 2015-01-27 2026-03-11 Lesaffre et Compagnie Pharmaceutical composition comprising vitamin k2 for use in the treatment or prevention of melanoma
TW201927292A (zh) 2017-12-13 2019-07-16 大陸商上海小午醫藥科技有限公司 一種用於預防或治療與egfr被抑制相關疾病的方法
AU2019254237B2 (en) 2018-04-16 2025-01-30 Onquality Pharmaceuticals China Ltd. Method for preventing or treating side effects of cancer therapy

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012236857A (ja) * 2005-04-15 2012-12-06 Albert Einstein College Of Medicine Of Yeshiva Univ 抗egfr療法に二次的な皮疹の予防および処置のためのビタミンk
JP2023132190A (ja) * 2022-03-10 2023-09-22 学校法人福岡大学 ケモカインccl5発現抑制剤

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JP5620443B2 (ja) 2014-11-05
EP1871353A2 (en) 2008-01-02
US20090209652A1 (en) 2009-08-20
US20130225690A1 (en) 2013-08-29
US20100324148A1 (en) 2010-12-23
JP2012236857A (ja) 2012-12-06
CA2603785C (en) 2014-07-22
KR20070121843A (ko) 2007-12-27
HK1111920A1 (en) 2008-11-07
EP2305224A3 (en) 2011-12-14
WO2006113479A3 (en) 2007-05-10
EP2494965A3 (en) 2013-01-02
US7745494B2 (en) 2010-06-29
CA2851079A1 (en) 2006-10-26
EP1871353B1 (en) 2010-12-22
ES2358528T3 (es) 2011-05-11
CA2603785A1 (en) 2006-10-26
DK1871353T3 (da) 2011-04-04
WO2006113479A2 (en) 2006-10-26
KR101332869B1 (ko) 2013-11-25
DE602006019074D1 (de) 2011-02-03
EP2305224B1 (en) 2015-03-11
EP1871353A4 (en) 2009-06-24
CY1111786T1 (el) 2015-10-07
EP2494965A2 (en) 2012-09-05
PT1871353E (pt) 2011-03-29
US8283382B2 (en) 2012-10-09
US20090239952A1 (en) 2009-09-24
ATE492275T1 (de) 2011-01-15
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