KR101332869B1 - 항-ｅｇｆｒ 치료법에 속발된 피부 발진의 예방 및 치료를위한 비타민 ｋ - Google Patents

항-ｅｇｆｒ 치료법에 속발된 피부 발진의 예방 및 치료를위한 비타민 ｋ Download PDF

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KR101332869B1
KR101332869B1 KR1020077026480A KR20077026480A KR101332869B1 KR 101332869 B1 KR101332869 B1 KR 101332869B1 KR 1020077026480 A KR1020077026480 A KR 1020077026480A KR 20077026480 A KR20077026480 A KR 20077026480A KR 101332869 B1 KR101332869 B1 KR 101332869B1
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South Korea
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egfr
vitamin
skin
pharmaceutical composition
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Korean (ko)
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KR20070121843A (ko
Inventor
로만 페레즈-솔러
이-헤 링
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알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티
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Application filed by 알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티 filed Critical 알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020077026480A 2005-04-15 2006-04-12 항-ｅｇｆｒ 치료법에 속발된 피부 발진의 예방 및 치료를위한 비타민 ｋ Expired - Fee Related KR101332869B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67156305P 2005-04-15 2005-04-15
US60/671,563 2005-04-15
PCT/US2006/014158 WO2006113479A2 (en) 2005-04-15 2006-04-12 Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy

Publications (2)

Publication Number Publication Date
KR20070121843A KR20070121843A (ko) 2007-12-27
KR101332869B1 true KR101332869B1 (ko) 2013-11-25

Family

ID=37115750

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077026480A Expired - Fee Related KR101332869B1 (ko) 2005-04-15 2006-04-12 항-ｅｇｆｒ 치료법에 속발된 피부 발진의 예방 및 치료를위한 비타민 ｋ

Country Status (13)

Country Link
US (4) US7745494B2 (enExample)
EP (3) EP1871353B1 (enExample)
JP (2) JP2008536865A (enExample)
KR (1) KR101332869B1 (enExample)
AT (1) ATE492275T1 (enExample)
AU (1) AU2006236633B2 (enExample)
CA (2) CA2851079A1 (enExample)
CY (1) CY1111786T1 (enExample)
DE (1) DE602006019074D1 (enExample)
DK (1) DK1871353T3 (enExample)
ES (1) ES2358528T3 (enExample)
PT (1) PT1871353E (enExample)
WO (1) WO2006113479A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
CA2851079A1 (en) 2005-04-15 2006-10-26 Albert Einstein College Of Medicine Of Yeshiva University Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy
EP2043685B1 (en) * 2006-07-03 2015-12-23 Genmab A/S Prevention of rash in patients undergoing anti-egfr therapy
US8815953B2 (en) * 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
US20100010100A1 (en) * 2008-07-09 2010-01-14 Hinman Andrew W Dermatological compositions with anti-aging and skin even-toning properties
US20100029784A1 (en) * 2008-07-30 2010-02-04 Hinman Andrew W Naphthoquinone compositions with anti-aging, anti-inflammatory and skin even-toning properties
JP5765634B2 (ja) 2008-10-21 2015-08-19 スレッシュホールド ファーマシューティカルズ， インコーポレイテッド 低酸素活性化型プロドラッグを用いるがんの処置
CN102458473A (zh) * 2009-06-26 2012-05-16 英属开曼群岛商安盛开发药物股份有限公司 治疗或减缓粘膜皮肤或眼睛毒性的方法
ITPD20100090A1 (it) * 2010-03-22 2011-09-23 Sanitas Farmaceutici S R L Formulazione topica per il trattamento di eruzioni cutanee, in particolare conseguenti a trattamenti con farmaci anti egfr
WO2012111187A1 (ja) 2011-02-14 2012-08-23 株式会社Ｊ－オイルミルズ 皮膚コラーゲン産生促進剤
EP2712613B1 (en) * 2012-09-28 2017-02-08 Pharmadab d.o.o. Vitamin K1 and uses thereof
US9421297B2 (en) 2014-04-02 2016-08-23 Adhezion Biomedical, Llc Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides
WO2016120341A2 (en) 2015-01-27 2016-08-04 Vitak B.V. Epidermal skin health
CN111601617A (zh) 2017-12-13 2020-08-28 上海岸阔医药科技有限公司 一种用于预防或治疗与egfr 被抑制相关疾病的方法
JP7520366B2 (ja) 2018-04-16 2024-07-23 オンクオリティー ファーマシューティカルズ チャイナ リミテッド 腫瘍療法の副作用の予防または治療方法

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WO2003101415A1 (en) 2002-06-01 2003-12-11 The Boots Company Plc Compositions comprisins vitamin k

Also Published As

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ES2358528T3 (es) 2011-05-11
CA2603785C (en) 2014-07-22
EP2305224A2 (en) 2011-04-06
CY1111786T1 (el) 2015-10-07
EP2305224B1 (en) 2015-03-11
EP1871353A2 (en) 2008-01-02
AU2006236633A1 (en) 2006-10-26
JP2012236857A (ja) 2012-12-06
DK1871353T3 (da) 2011-04-04
HK1111920A1 (en) 2008-11-07
EP1871353A4 (en) 2009-06-24
US20090209652A1 (en) 2009-08-20
CA2603785A1 (en) 2006-10-26
AU2006236633B2 (en) 2012-03-29
JP5620443B2 (ja) 2014-11-05
US7745494B2 (en) 2010-06-29
US20090239952A1 (en) 2009-09-24
WO2006113479A3 (en) 2007-05-10
EP2494965A2 (en) 2012-09-05
US20100324148A1 (en) 2010-12-23
ATE492275T1 (de) 2011-01-15
EP2494965A3 (en) 2013-01-02
EP1871353B1 (en) 2010-12-22
CA2851079A1 (en) 2006-10-26
PT1871353E (pt) 2011-03-29
WO2006113479A2 (en) 2006-10-26
KR20070121843A (ko) 2007-12-27
US8283382B2 (en) 2012-10-09
EP2305224A3 (en) 2011-12-14
DE602006019074D1 (de) 2011-02-03
JP2008536865A (ja) 2008-09-11
US20130225690A1 (en) 2013-08-29

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