PT1871353E - Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr - Google Patents

Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr Download PDF

Info

Publication number
PT1871353E
PT1871353E PT06750246T PT06750246T PT1871353E PT 1871353 E PT1871353 E PT 1871353E PT 06750246 T PT06750246 T PT 06750246T PT 06750246 T PT06750246 T PT 06750246T PT 1871353 E PT1871353 E PT 1871353E
Authority
PT
Portugal
Prior art keywords
vitamin
egfr
skin
therapy
formulated
Prior art date
Application number
PT06750246T
Other languages
English (en)
Portuguese (pt)
Inventor
Yi-He Ling
Roman Perez-Soler
Original Assignee
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37115750&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1871353(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Einstein Coll Med filed Critical Einstein Coll Med
Publication of PT1871353E publication Critical patent/PT1871353E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT06750246T 2005-04-15 2006-04-12 Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr PT1871353E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67156305P 2005-04-15 2005-04-15

Publications (1)

Publication Number Publication Date
PT1871353E true PT1871353E (pt) 2011-03-29

Family

ID=37115750

Family Applications (1)

Application Number Title Priority Date Filing Date
PT06750246T PT1871353E (pt) 2005-04-15 2006-04-12 Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr

Country Status (13)

Country Link
US (4) US7745494B2 (enExample)
EP (3) EP1871353B1 (enExample)
JP (2) JP2008536865A (enExample)
KR (1) KR101332869B1 (enExample)
AT (1) ATE492275T1 (enExample)
AU (1) AU2006236633B2 (enExample)
CA (2) CA2603785C (enExample)
CY (1) CY1111786T1 (enExample)
DE (1) DE602006019074D1 (enExample)
DK (1) DK1871353T3 (enExample)
ES (1) ES2358528T3 (enExample)
PT (1) PT1871353E (enExample)
WO (1) WO2006113479A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595378B2 (en) 2001-06-13 2009-09-29 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
PT1871353E (pt) * 2005-04-15 2011-03-29 Einstein Coll Med Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr
EP2043685B1 (en) * 2006-07-03 2015-12-23 Genmab A/S Prevention of rash in patients undergoing anti-egfr therapy
US8815953B2 (en) * 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
WO2010005989A1 (en) * 2008-07-09 2010-01-14 Edison Pharmaceuticals, Inc. Dermatological compositions with anti-aging and skin even-toning properties
WO2010014361A1 (en) * 2008-07-30 2010-02-04 Edison Pharmaceuticals, Inc. Naphthoquinone compositions with anti-aging, anti- inflammatory and skin even-toning properties
US8946275B2 (en) 2008-10-21 2015-02-03 Threshold Pharmaceuticals, Inc. Treatment of cancer using hypoxia activated prodrugs
AU2009348848B2 (en) * 2009-06-26 2012-10-25 Sunny Pharmtech, Inc. Method for treating or ameliorating mucocutaneous or ocular toxicities
ITPD20100090A1 (it) * 2010-03-22 2011-09-23 Sanitas Farmaceutici S R L Formulazione topica per il trattamento di eruzioni cutanee, in particolare conseguenti a trattamenti con farmaci anti egfr
CN103347505B (zh) 2011-02-14 2015-02-04 J-制油株式会社 皮肤胶原蛋白增强剂
EP2712613B1 (en) * 2012-09-28 2017-02-08 Pharmadab d.o.o. Vitamin K1 and uses thereof
US9421297B2 (en) 2014-04-02 2016-08-23 Adhezion Biomedical, Llc Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides
EP3250180A2 (en) 2015-01-27 2017-12-06 VitaK B.V. Epidermal skin health
WO2019114705A1 (zh) 2017-12-13 2019-06-20 上海小午医药科技有限公司 一种用于预防或治疗与egfr被抑制相关疾病的方法
TW201943428A (zh) 2018-04-16 2019-11-16 大陸商上海岸闊醫藥科技有限公司 預防或治療腫瘤療法副作用的方法

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA84119A (en) 1903-11-06 1903-12-01 Edward M. Haymaker Cover and strainer for milk pails
CA91784A (en) 1904-10-05 1905-02-28 William Stevenson Dining and billiard table
US3155031A (en) 1962-03-16 1964-11-03 Babco Products Inc Printing and digital coding machine
US4294852A (en) * 1973-11-01 1981-10-13 Johnson & Johnson Skin treating compositions
EP0015436B1 (de) 1979-03-08 1982-02-03 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur stereospezifischen Herstellung von Verbindungen der Vitamin K1- und K2-Reihe sowie neue Ausgangsprodukte in diesem Verfahren
JPS6025918A (ja) * 1983-07-25 1985-02-08 Ajinomoto Co Inc 脂溶性薬物含有水性液
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
DE3514724A1 (de) 1985-04-24 1986-10-30 Albin F. Dr. 4200 Oberhausen Jereb Salbe zur verbeugung und behandlung von augen- und hauterkrankungen
JPS62294636A (ja) 1986-05-21 1987-12-22 Eisai Co Ltd 2−メチル−1,4−ナフトキノンの製造法
US5180747A (en) * 1989-02-28 1993-01-19 Nisshin Flour Milling Co., Ltd. Stabilized fat-soluble vitamin compositions
ZA902066B (en) 1989-04-14 1990-12-28 Minnesota Mining & Mfg Solid gel external drug delivery system
US4966779A (en) * 1989-12-21 1990-10-30 Basf Corporation Stable, water miscible emulsion comprising a fat-soluble vitamin
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5155031A (en) 1990-06-07 1992-10-13 Posner Barry I Use of pervanadate as an inhibitor of phosphotyrosine phosphatase
FR2672288B1 (fr) 1991-02-06 1993-04-23 Oreal Nouveaux amides dipeptidiques derivant de la glycyl-serine, utilisables, notamment dans des compositions cosmetiques, pharmaceutiques ou alimentaires.
DE4141351A1 (de) * 1991-12-14 1993-06-17 Basf Ag Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung
US6537579B1 (en) * 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5643765A (en) 1993-04-06 1997-07-01 University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
EP0636598B1 (en) 1993-07-26 1997-04-09 Eisai Chemical Co., Ltd. Preparation process of naphthoquinone derivatives and intermediates for the preparation thereof
US5510391A (en) 1993-10-22 1996-04-23 Mayapple Holdings, Llc Method of treating blood vessel disorders of the skin using vitamin K
FR2719219B1 (fr) * 1994-05-02 1996-06-21 Rocher Yves Biolog Vegetale Composition cosmétique ou pharmaceutique à usage topique comprenant des vésicules lipidiques.
US5637741A (en) 1994-09-27 1997-06-10 Kuraray Co., Ltd. Process for producing 2-methyl-1,4-naphthoquinone
JPH09143042A (ja) * 1995-11-24 1997-06-03 Lion Corp 口腔用組成物
WO1997039746A1 (en) 1996-04-22 1997-10-30 Advanced Polymer Systems, Inc. Method of and composition for treating disorders of the skin using vitamin k
KR0178456B1 (ko) 1996-04-25 1999-05-15 김흥기 2-메틸-1,4-나프토퀴논(비타민 k3)의 제조방법
SE9601665D0 (sv) * 1996-04-30 1996-04-30 Bioglan Ab Biologically active composition
US6110891A (en) * 1996-06-21 2000-08-29 Alizyme Therapeutics Ltd. Lectin compositions and uses thereof
DE19642359A1 (de) * 1996-10-14 1998-04-16 Basf Ag Stabile Emulsionen und Trockenpulver von Mischungen fettlöslicher Vitamine, deren Herstellung und Verwendung
US5916749A (en) * 1996-12-13 1999-06-29 Incyte Pharmaceuticals, Inc. Human phosphatase inhibitor protein
US6426078B1 (en) * 1997-03-17 2002-07-30 Roche Vitamins Inc. Oil in water microemulsion
US6599513B2 (en) * 1997-05-27 2003-07-29 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
US6372234B1 (en) * 1997-05-27 2002-04-16 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
US6696484B2 (en) * 1997-10-31 2004-02-24 University Of Chicago Office Of Technology And Intellectual Property Method and compositions for regulation of 5-alpha reductase activity
KR20010031501A (ko) * 1997-10-31 2001-04-16 추후제출 5-알파 환원효소 활성을 조절하는 방법 및 조성물
US6013665A (en) * 1997-12-16 2000-01-11 Abbott Laboratories Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides
JP2002517436A (ja) * 1998-06-11 2002-06-18 ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュージャージー アデノシン二リン酸リボシルトランスフェラーゼの阻害を介する創傷処置
US6207176B1 (en) * 1998-09-14 2001-03-27 National Starch And Chemical Investment Holding Corporation Starch based adhesives for skin cleaning tape
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6187822B1 (en) * 1999-06-11 2001-02-13 University Of Medicine & Dentistry Of Nj Wound treatment through inhibition of adenosine diphosphate ribosyl transferase
US6524594B1 (en) * 1999-06-23 2003-02-25 Johnson & Johnson Consumer Companies, Inc. Foaming oil gel compositions
US7927612B2 (en) * 2000-01-19 2011-04-19 Baofa Yu Combinations and methods for treating neoplasms
DE10003786A1 (de) 2000-01-28 2001-08-02 Merck Patent Gmbh Galenische Formulierung
US8883856B2 (en) * 2000-02-28 2014-11-11 John Jackson Compositions and methods for the treatment of inflammatory diseases using topoisomerase inhibitors
ATE311766T1 (de) 2000-03-17 2005-12-15 Verfahren zur herstellung öliger suspensionen wasserlöslicher vitamine
ATE297751T1 (de) * 2000-03-20 2005-07-15 Pfizer Prod Inc Kombinationstherapie mit keratinozyten- wachstumfaktor und ein epidermis-wachstumfaktor inhibitor
US20040047852A1 (en) * 2001-03-02 2004-03-11 Kennedy Thomas Preston Method of treating cancer
US20020040011A1 (en) 2000-06-01 2002-04-04 Brown Dennis M. Naphthoquinone compositions and uses thereof
PL342071A1 (en) 2000-08-18 2001-02-12 Szolomicka Orfinger Irena Cosmetic cream
GB0022079D0 (en) 2000-09-08 2000-10-25 Inst Of Molecul & Cell Biology Novel protein tyrosine phosphatase inhibitor
US6660306B2 (en) * 2000-10-12 2003-12-09 Mickey L. Peshoff Wound healing compound
US7094431B2 (en) * 2000-10-12 2006-08-22 Mickey L. Peshoff Method of healing skin wounds in mammals and a composition therefor
US6774100B2 (en) * 2000-12-06 2004-08-10 Imaginative Research Associates, Inc. Anhydrous creams, lotions and gels
US7604812B2 (en) * 2000-12-15 2009-10-20 Patrick Franke Hypoallergenic and non-irritant skin care formulations
DK1214930T3 (da) 2000-12-15 2004-07-26 Patrick Dr Franke Hypoallergene og ikke-irriterende formuleringer til hudpleje
US6780439B2 (en) * 2001-03-06 2004-08-24 J. Ronald Wilk Wound treatment solution and method for using same
US6579994B2 (en) 2001-03-29 2003-06-17 Council Of Scientific And Industrial Research Process for preparation of 2-Methyl-1,4-naphthoquinone
WO2003031566A2 (en) * 2001-07-20 2003-04-17 Human Genome Sciences, Inc. Keratinocyte derived interferon
US6812220B2 (en) 2001-08-29 2004-11-02 University Of British Columbia Pharmaceutical compositions and methods relating to fucans
US20070238697A1 (en) * 2001-08-29 2007-10-11 University Of British Columbia Pharmaceutical compositions and methods relating to fucans
US8156471B2 (en) * 2001-11-09 2012-04-10 Oracle International Corporation Multi-language execution method
US7405188B2 (en) * 2001-12-12 2008-07-29 Wsp Chemicals & Technology, Llc Polymeric gel system and compositions for treating keratin substrates containing same
AU2002364051A1 (en) * 2002-01-24 2003-09-02 Children's Medical Center Corporation Anti-cancer combination and use thereof
JP2003226639A (ja) * 2002-01-31 2003-08-12 Hisamitsu Pharmaceut Co Inc 神経成長因子活性増強剤としてのビタミンk類を含む医薬組成物およびその使用
US20030170187A1 (en) 2002-03-01 2003-09-11 Alfred Marchal Skin treatments containing nano-sized vitamin K
GB0212749D0 (en) 2002-06-01 2002-07-10 Boots Co Plc Personal care compositions
GB0220182D0 (en) 2002-08-30 2002-10-09 Cardiovascular Res Inst Maastr Organic compounds
US7326690B2 (en) * 2002-10-30 2008-02-05 Bach Pharma, Inc. Modulation of cell fates and activities by phthalazinediones
WO2004098569A1 (en) * 2003-04-18 2004-11-18 Northeastern University Micelle delivery system loaded with a pharmaceutical agent
JP2005020651A (ja) 2003-06-30 2005-01-20 Hitachi Ltd タイムスタンプ情報検証方法
US7320797B2 (en) * 2003-08-29 2008-01-22 Bioderm Research Antiaging cosmetic delivery systems
EP1667659A1 (en) 2003-09-30 2006-06-14 Acusphere, Inc. Injectable, oral, or topical sustained release pharmaceutical formulations
US20050092969A1 (en) * 2003-10-08 2005-05-05 Kaneka Corporation Method of stabilizing compound having quinone skeleton and stabilized composition
JP2005206521A (ja) 2004-01-22 2005-08-04 Nippon Menaade Keshohin Kk 抗菌剤
KR20060002239A (ko) * 2004-07-01 2006-01-09 삼성전자주식회사 레이저 출력 제어장치
WO2006029893A2 (en) 2004-09-17 2006-03-23 Oystershell Nv Composition for inhibiting or preventing the formation of a biofilm
CN101068561A (zh) 2004-10-06 2007-11-07 蒂尔坦制药有限公司 用于加强抗血管生成疗法的方法和组合物
WO2006107827A1 (en) 2005-04-05 2006-10-12 Creighton University Skin bonding process
PT1871353E (pt) * 2005-04-15 2011-03-29 Einstein Coll Med Vitamina k para prevenção e tratamento de irritação de pele secundária a terapia anti-egfr
US20060275504A1 (en) * 2005-06-07 2006-12-07 Tty Biopharm Company Limited Methods and compositions for augmenting cancer chemotherapeutic agents
US20070025950A1 (en) * 2005-07-28 2007-02-01 Elson Melvin L Composition and method for treating cellulite
US7252816B1 (en) 2006-03-29 2007-08-07 Dow Pharmaceutical Sciences Topical acne vulgairs medication with a sunscreen
US8507555B2 (en) 2006-06-16 2013-08-13 Summa Health System Non-toxic anti-cancer drug combining ascorbate, magnesium and a naphthoquinone
WO2008004231A1 (en) 2006-07-07 2008-01-10 Tiltan Pharma Ltd. Anti-cancer therapy comprising an h2-blocker, at least one antiinflammatory agent and a cytotoxic agent

Also Published As

Publication number Publication date
US20090209652A1 (en) 2009-08-20
US20130225690A1 (en) 2013-08-29
WO2006113479A3 (en) 2007-05-10
JP2008536865A (ja) 2008-09-11
JP2012236857A (ja) 2012-12-06
US20090239952A1 (en) 2009-09-24
CA2603785C (en) 2014-07-22
WO2006113479A2 (en) 2006-10-26
HK1111920A1 (en) 2008-11-07
EP1871353A2 (en) 2008-01-02
EP2305224A2 (en) 2011-04-06
AU2006236633B2 (en) 2012-03-29
EP2305224B1 (en) 2015-03-11
KR20070121843A (ko) 2007-12-27
EP2494965A2 (en) 2012-09-05
DK1871353T3 (da) 2011-04-04
US8283382B2 (en) 2012-10-09
EP2305224A3 (en) 2011-12-14
EP2494965A3 (en) 2013-01-02
AU2006236633A1 (en) 2006-10-26
US7745494B2 (en) 2010-06-29
US20100324148A1 (en) 2010-12-23
ATE492275T1 (de) 2011-01-15
EP1871353A4 (en) 2009-06-24
ES2358528T3 (es) 2011-05-11
CA2851079A1 (en) 2006-10-26
JP5620443B2 (ja) 2014-11-05
DE602006019074D1 (de) 2011-02-03
EP1871353B1 (en) 2010-12-22
CA2603785A1 (en) 2006-10-26
CY1111786T1 (el) 2015-10-07
KR101332869B1 (ko) 2013-11-25

Similar Documents

Publication Publication Date Title
US8283382B2 (en) Vitamin K for prevention and treatment of skin rash secondary to anti-EGFR therapy
Kwon et al. Melatonin potentiates the neuroprotective properties of resveratrol against beta-amyloid-induced neurodegeneration by modulating AMP-activated protein kinase pathways
Gong et al. Downregulation of STAT3/NF‐κB potentiates gemcitabine activity in pancreatic cancer cells
Allegra et al. Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression
IL133976A (en) Agents for the treatment of skin disorders
KR20160094451A (ko) S-아데노실메티오닌 및 갈산 에스테르가 포함된 조성물
RU2346685C2 (ru) Композиция и способы профилактики и лечения рака предстательной железы человека
Hersant et al. Over the counter supplements for memory: a review of available evidence
Moraes et al. Reduction of oxidative damage and inflammatory response in the diaphragm muscle of mdx mice using iron chelator deferoxamine
Yabuki et al. The T-type calcium channel enhancer SAK3 inhibits neuronal death following transient brain ischemia via nicotinic acetylcholine receptor stimulation
US20160220589A1 (en) Compositions and methods for the treatment of skin disorders
TW202038960A (zh) Mcl-1抑制劑及米哚妥林(midostaurin)之組合,其用途及醫藥組合物
US20240016821A1 (en) Drink product and use thereof
Prasad et al. RETRACTED: Curcumin-Free Turmeric Exhibits Activity against Human HCT-116 Colon Tumor Xenograft: Comparison with Curcumin and Whole Turmeric
US20240066017A1 (en) Prevention or treatment of brain disease and adverse effects of cholinesterase inhibitors
AU2014274563A1 (en) Vitamin K for prevention and treatment of skin rash secondary to anti-EGFR therapy
HK1153125A (en) Vitamin k analog for treatment of skin or mucosal ulceration
HK1175691A (en) Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy
HK1111920B (en) Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy
JP2022509552A (ja) 抗がん用組成物
US20140274965A1 (en) Drink Product and Use Thereof
Honma et al. Induction of differentiation of human myeloid leukemia cells by novel synthetic neurotrophic pyrimidine derivatives