JP2008536496A5 - - Google Patents
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- Publication number
- JP2008536496A5 JP2008536496A5 JP2008505707A JP2008505707A JP2008536496A5 JP 2008536496 A5 JP2008536496 A5 JP 2008536496A5 JP 2008505707 A JP2008505707 A JP 2008505707A JP 2008505707 A JP2008505707 A JP 2008505707A JP 2008536496 A5 JP2008536496 A5 JP 2008536496A5
- Authority
- JP
- Japan
- Prior art keywords
- deletion
- mtdna
- prostate cancer
- pcr analysis
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020005196 Mitochondrial DNA Proteins 0.000 claims 18
- 230000037430 deletion Effects 0.000 claims 15
- 238000012217 deletion Methods 0.000 claims 15
- 238000000034 method Methods 0.000 claims 15
- 206010060862 Prostate cancer Diseases 0.000 claims 9
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 8
- 238000010222 PCR analysis Methods 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 238000003753 real-time PCR Methods 0.000 claims 5
- 230000035772 mutation Effects 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 claims 3
- 208000000453 Skin Neoplasms Diseases 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 230000002285 radioactive effect Effects 0.000 claims 2
- 201000000849 skin cancer Diseases 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 108010035095 NADH dehydrogenase subunit 4 Proteins 0.000 claims 1
- 102100021506 NADH-ubiquinone oxidoreductase chain 4 Human genes 0.000 claims 1
- 102100021452 NADH-ubiquinone oxidoreductase chain 4L Human genes 0.000 claims 1
- 101710151478 NADH-ubiquinone oxidoreductase chain 4L Proteins 0.000 claims 1
- 101710106577 NADH-ubiquinone oxidoreductase chain 5 Proteins 0.000 claims 1
- 102100036971 NADH-ubiquinone oxidoreductase chain 5 Human genes 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 108020004566 Transfer RNA Proteins 0.000 claims 1
- 239000000090 biomarker Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 230000003211 malignant effect Effects 0.000 claims 1
- 238000013507 mapping Methods 0.000 claims 1
- 238000013188 needle biopsy Methods 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000036561 sun exposure Effects 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67201605P | 2005-04-18 | 2005-04-18 | |
| US60/672,016 | 2005-04-18 | ||
| US72152205P | 2005-09-29 | 2005-09-29 | |
| US60/721,522 | 2005-09-29 | ||
| US78987206P | 2006-04-07 | 2006-04-07 | |
| US60/789,872 | 2006-04-07 | ||
| PCT/CA2006/000652 WO2006111029A1 (en) | 2005-04-18 | 2006-04-18 | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012101409A Division JP6134890B2 (ja) | 2005-04-18 | 2012-04-26 | 日光曝露、前立腺癌および他の癌の検出用の診断ツールとしての、ミトコンドリアの突然変異および再配置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008536496A JP2008536496A (ja) | 2008-09-11 |
| JP2008536496A5 true JP2008536496A5 (enExample) | 2009-05-28 |
| JP5537804B2 JP5537804B2 (ja) | 2014-07-02 |
Family
ID=37114687
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008505707A Expired - Fee Related JP5537804B2 (ja) | 2005-04-18 | 2006-04-18 | 日光曝露、前立腺癌および他の癌の検出用の診断ツールとしての、ミトコンドリアの突然変異および再配置 |
| JP2012101409A Expired - Fee Related JP6134890B2 (ja) | 2005-04-18 | 2012-04-26 | 日光曝露、前立腺癌および他の癌の検出用の診断ツールとしての、ミトコンドリアの突然変異および再配置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012101409A Expired - Fee Related JP6134890B2 (ja) | 2005-04-18 | 2012-04-26 | 日光曝露、前立腺癌および他の癌の検出用の診断ツールとしての、ミトコンドリアの突然変異および再配置 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8008008B2 (enExample) |
| EP (2) | EP1877559B1 (enExample) |
| JP (2) | JP5537804B2 (enExample) |
| KR (1) | KR101363032B1 (enExample) |
| CN (2) | CN101248180B (enExample) |
| AT (1) | ATE484589T1 (enExample) |
| AU (1) | AU2006238390B2 (enExample) |
| CA (2) | CA2606156C (enExample) |
| DE (1) | DE602006017534D1 (enExample) |
| DK (1) | DK1877559T3 (enExample) |
| ES (1) | ES2354452T3 (enExample) |
| NZ (2) | NZ587665A (enExample) |
| PT (1) | PT1877559E (enExample) |
| SG (1) | SG2014011837A (enExample) |
| WO (1) | WO2006111029A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130022979A1 (en) * | 2005-04-18 | 2013-01-24 | Genesis Genomics Inc. | 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER |
| DE602006017534D1 (de) * | 2005-04-18 | 2010-11-25 | Mitomics Inc | Mitochondriale mutationen und umlagerungen als diagnostisches werkzeug zum nachweis von sonneneinstrahlung, prostatakrebs und anderen krebserkrankungen |
| CN100526453C (zh) * | 2005-05-20 | 2009-08-12 | 麦克奥迪实业集团有限公司 | 激光显微切割后细胞收集方法 |
| JP2008543300A (ja) * | 2005-06-16 | 2008-12-04 | バイオツールズ バイオテクノロジカル アンド メディカル ラボラトリーズ， エス． アー． | 測定可能なシグナルの直接生成を用いた核酸検出法 |
| US20080254530A1 (en) * | 2007-02-27 | 2008-10-16 | Gettysburg College | Isolation and characterization of a single mitochondrion |
| EP2634267B1 (en) | 2007-09-26 | 2015-02-18 | Mitomics Inc. | 3.4 kb mitochondrial DNA deletion for use in the detection of cancer |
| CN101896622B (zh) * | 2007-10-11 | 2015-07-22 | 米托米克斯公司 | 测定皮肤样本中mc1r变体和线粒体标记物的方法 |
| WO2009046514A1 (en) * | 2007-10-11 | 2009-04-16 | Genesis Genomics Inc. | Methods for non-invasive collection of skin cells for dna analysis |
| US20100311057A1 (en) * | 2007-11-09 | 2010-12-09 | Ryan Parr | Mitochondrial DNA Deletion Between About Residues 12317-16254 for Use in the Detection of Cancer |
| KR101693387B1 (ko) * | 2008-03-28 | 2017-01-05 | 엠디엔에이 라이프 사이언시즈 인코퍼레이티드 | 비정상적인 미토콘드리아 ｄｎａ, 그것에 연관된 융합 트랜스크립트 및 혼성화 프로브 |
| BRPI0917711A2 (pt) * | 2008-08-28 | 2017-06-20 | Astute Medical Inc | método para avaliar o estado renal em um paciente, e, uso de um ou mais marcadores de lesão renal |
| JP5947544B2 (ja) * | 2008-08-29 | 2016-07-06 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
| AU2009308375B2 (en) * | 2008-10-21 | 2015-06-25 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2010048346A1 (en) * | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2913676A1 (en) | 2008-11-10 | 2015-09-02 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5735922B2 (ja) * | 2008-11-22 | 2015-06-17 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法 |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AU2010234238B2 (en) * | 2009-03-27 | 2016-07-28 | Mdna Life Sciences Inc. | Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor |
| US12129514B2 (en) | 2009-04-30 | 2024-10-29 | Molecular Loop Biosolutions, Llc | Methods and compositions for evaluating genetic markers |
| WO2010126614A2 (en) | 2009-04-30 | 2010-11-04 | Good Start Genetics, Inc. | Methods and compositions for evaluating genetic markers |
| JP5827226B2 (ja) | 2009-08-07 | 2015-12-02 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| NZ628085A (en) | 2009-11-07 | 2015-12-24 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP2011115098A (ja) * | 2009-12-04 | 2011-06-16 | Nippon Menaade Keshohin Kk | 加齢による皮膚明度の低下を予測する皮膚評価方法 |
| ES2818138T3 (es) | 2009-12-20 | 2021-04-09 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| EP2666872B1 (en) | 2010-02-05 | 2016-04-27 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011106746A1 (en) | 2010-02-26 | 2011-09-01 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| SG183562A1 (en) * | 2010-03-01 | 2012-10-30 | Mitomics Inc | Uv associated mtdna fusion transcripts and methods and uses thereof |
| EP2585825B1 (en) | 2010-06-23 | 2018-01-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2585827A4 (en) | 2010-06-23 | 2013-12-04 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency |
| US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
| CN110016499B (zh) | 2011-04-15 | 2023-11-14 | 约翰·霍普金斯大学 | 安全测序系统 |
| WO2013058907A1 (en) | 2011-10-17 | 2013-04-25 | Good Start Genetics, Inc. | Analysis methods |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
| US8812422B2 (en) | 2012-04-09 | 2014-08-19 | Good Start Genetics, Inc. | Variant database |
| US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
| CN104812947B (zh) * | 2012-07-17 | 2018-04-27 | 考希尔股份有限公司 | 检测遗传变异的系统和方法 |
| PL2912468T3 (pl) | 2012-10-29 | 2019-04-30 | Univ Johns Hopkins | Test papanicolaou pod kątem raka jajnika i endometrium |
| WO2014071178A1 (en) * | 2012-11-05 | 2014-05-08 | Icahn School Of Medicine At Mount Sinai | Method of isolating pure mitochondrial dna |
| ES2482866B1 (es) * | 2012-11-22 | 2015-05-12 | Consejo Superior De Investigaciones Científicas (Csic) | Método de diagnóstico y/o pronóstico de enfermedades neurodegenerativas. |
| JP6681195B2 (ja) | 2013-01-17 | 2020-04-15 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| US8778609B1 (en) | 2013-03-14 | 2014-07-15 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
| EP3005200A2 (en) | 2013-06-03 | 2016-04-13 | Good Start Genetics, Inc. | Methods and systems for storing sequence read data |
| US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
| US11041203B2 (en) | 2013-10-18 | 2021-06-22 | Molecular Loop Biosolutions, Inc. | Methods for assessing a genomic region of a subject |
| US9745611B2 (en) * | 2014-05-06 | 2017-08-29 | Genewiz Inc. | Methods and kits for identifying microorganisms in a sample |
| WO2015175530A1 (en) | 2014-05-12 | 2015-11-19 | Gore Athurva | Methods for detecting aneuploidy |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| CN104062294A (zh) * | 2014-07-11 | 2014-09-24 | 青岛千士医疗科技有限公司 | 一种支气管/肺上皮细胞线粒体损伤的检测方法 |
| US20160048608A1 (en) | 2014-08-15 | 2016-02-18 | Good Start Genetics, Inc. | Systems and methods for genetic analysis |
| US11408024B2 (en) | 2014-09-10 | 2022-08-09 | Molecular Loop Biosciences, Inc. | Methods for selectively suppressing non-target sequences |
| EP3224595A4 (en) | 2014-09-24 | 2018-06-13 | Good Start Genetics, Inc. | Process control for increased robustness of genetic assays |
| KR102210104B1 (ko) | 2014-10-17 | 2021-02-01 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
| US10066259B2 (en) | 2015-01-06 | 2018-09-04 | Good Start Genetics, Inc. | Screening for structural variants |
| EP3091083B1 (en) | 2015-05-07 | 2017-11-08 | Latvian Biomedical Research and Study Centre | A kit for detecting mutation or polymorphism in the human mitochondrial dna |
| CN106338423B (zh) | 2015-07-10 | 2020-07-14 | 三斯坎公司 | 组织学染色的空间复用 |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| BR112020002555A2 (pt) | 2017-08-07 | 2020-08-11 | The Johns Hopkins University | métodos e materiais para avaliar e tratar câncer |
| CN108827887B (zh) * | 2018-03-19 | 2021-05-18 | 陕西学前师范学院 | 一种商陆基因组大小估计方法及基因组大小测量系统 |
| EP3578671A1 (en) * | 2018-06-05 | 2019-12-11 | Universitat Autònoma De Barcelona | Method for evaluating risk of cardiovascular disease |
| CN109360656B (zh) * | 2018-08-20 | 2021-11-02 | 安徽大学 | 一种基于多目标演化算法的癌症检测方法 |
| EP3966323A4 (en) * | 2019-05-06 | 2024-04-24 | The Regents Of The University Of Michigan | TARGETED THERAPY |
| CN110378881B (zh) * | 2019-07-05 | 2020-03-24 | 北京航空航天大学 | 一种基于深度学习的肿瘤定位系统 |
| CN110358856B (zh) * | 2019-07-23 | 2023-04-07 | 四川省农业科学院生物技术核技术研究所 | 侧耳属线粒体nad4L基因的扩增引物及其在鉴定侧耳属物种中的应用 |
| CN113025633B (zh) * | 2019-12-09 | 2024-08-27 | 武汉纽福斯生物科技有限公司 | 编码人nadh脱氢酶亚单位1蛋白的核酸及其应用 |
| CA3170345A1 (en) | 2020-02-14 | 2021-08-19 | The Johns Hopkins University | Methods and materials for assessing nucleic acids |
| US20230235400A1 (en) * | 2020-06-04 | 2023-07-27 | The General Hospital Corporation | Methods of detecting mitochondrial diseases |
| CN117070511B (zh) * | 2023-08-16 | 2024-02-02 | 广州卿泽生物科技有限公司 | 一种用于扩增人类线粒体全基因组的引物组及其应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2356536A (en) * | 1939-07-18 | 1944-08-22 | Rzymkowski Johannes | Developing process |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US6027883A (en) | 1994-03-30 | 2000-02-22 | Mitokor | Optimal procedure for isolation of mutant mitochondrial alleles |
| US5565323A (en) | 1994-03-30 | 1996-10-15 | Mitokor | Cytochrome oxidase mutations aiding diagnosis of sporadic alzheimer's disease |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| JPH1099085A (ja) | 1996-05-16 | 1998-04-21 | Affymetrix Inc | ヒトミトコンドリアｄｎａの多形性 |
| JP3251219B2 (ja) | 1997-10-13 | 2002-01-28 | 雅嗣 田中 | ヒトミトコンドリアｄｎａを用いた遺伝子検出方法 |
| JP2002523061A (ja) | 1998-08-20 | 2002-07-30 | ザ ジョンズ ホプキンス ユニバーシティ | 腫瘍マーカーとしての微細なミトコンドリア突然変異 |
| US6605433B1 (en) | 1998-08-20 | 2003-08-12 | The Johns Hopkins University | Mitochondrial dosimeter |
| US20020068277A1 (en) * | 1998-11-20 | 2002-06-06 | Simpson Andrew John George | Method for determining nucleotide sequences using arbitrary primers and low stringency |
| EP1208225A2 (en) | 1999-04-20 | 2002-05-29 | Mitokor | Single nucleotide polymorphisms in mitochondrial genes that segregate with alzheimer's disease |
| SE0003286D0 (sv) | 2000-09-15 | 2000-09-15 | Ulf Gyllensten | Method and kit for human identification |
| US20030092019A1 (en) | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| US20030162174A1 (en) | 2001-06-11 | 2003-08-28 | Sutherland John W. | Detecting nucleic acid deletion sequences |
| WO2002101086A2 (en) * | 2001-06-11 | 2002-12-19 | 1304854 Ontario Ltd. | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| US20050026167A1 (en) * | 2001-06-11 | 2005-02-03 | Mark Birch-Machin | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| US20040191769A1 (en) * | 2001-07-24 | 2004-09-30 | Transgenomic, Inc. | Methods, compositions, and kits for mutation detection in mitochondrial DNA |
| CA2356536A1 (en) * | 2001-08-30 | 2003-02-28 | Emory University | Mitochondrial dna sequence alleles |
| SE0200817D0 (sv) * | 2002-03-15 | 2002-03-15 | Ulf Gyllensten | Method and kit for detection of mutations in mitochondrial DNA |
| US20050244851A1 (en) * | 2004-01-13 | 2005-11-03 | Affymetrix, Inc. | Methods of analysis of alternative splicing in human |
| DE602006017534D1 (de) * | 2005-04-18 | 2010-11-25 | Mitomics Inc | Mitochondriale mutationen und umlagerungen als diagnostisches werkzeug zum nachweis von sonneneinstrahlung, prostatakrebs und anderen krebserkrankungen |
-
2006
- 2006-04-18 DE DE602006017534T patent/DE602006017534D1/de active Active
- 2006-04-18 KR KR1020077026442A patent/KR101363032B1/ko not_active Expired - Fee Related
- 2006-04-18 AU AU2006238390A patent/AU2006238390B2/en not_active Ceased
- 2006-04-18 SG SG2014011837A patent/SG2014011837A/en unknown
- 2006-04-18 WO PCT/CA2006/000652 patent/WO2006111029A1/en not_active Ceased
- 2006-04-18 DK DK06741413.6T patent/DK1877559T3/da active
- 2006-04-18 CN CN2006800219031A patent/CN101248180B/zh active Active
- 2006-04-18 CN CN201310399746.XA patent/CN103789405B/zh not_active Expired - Fee Related
- 2006-04-18 JP JP2008505707A patent/JP5537804B2/ja not_active Expired - Fee Related
- 2006-04-18 NZ NZ587665A patent/NZ587665A/en not_active IP Right Cessation
- 2006-04-18 NZ NZ562928A patent/NZ562928A/en not_active IP Right Cessation
- 2006-04-18 PT PT06741413T patent/PT1877559E/pt unknown
- 2006-04-18 CA CA2606156A patent/CA2606156C/en active Active
- 2006-04-18 EP EP06741413A patent/EP1877559B1/en active Active
- 2006-04-18 AT AT06741413T patent/ATE484589T1/de active
- 2006-04-18 CA CA2792443A patent/CA2792443A1/en not_active Abandoned
- 2006-04-18 ES ES06741413T patent/ES2354452T3/es active Active
- 2006-04-18 EP EP10013553.2A patent/EP2339032B1/en not_active Not-in-force
-
2007
- 2007-10-18 US US11/975,390 patent/US8008008B2/en active Active
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2011
- 2011-08-30 US US13/221,618 patent/US20120058483A1/en not_active Abandoned
-
2012
- 2012-04-26 JP JP2012101409A patent/JP6134890B2/ja not_active Expired - Fee Related
-
2014
- 2014-08-27 US US14/470,627 patent/US9745632B2/en not_active Expired - Fee Related
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2017
- 2017-08-29 US US15/690,147 patent/US10907213B2/en active Active
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