JP2008536488A5 - - Google Patents
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- JP2008536488A5 JP2008536488A5 JP2008502127A JP2008502127A JP2008536488A5 JP 2008536488 A5 JP2008536488 A5 JP 2008536488A5 JP 2008502127 A JP2008502127 A JP 2008502127A JP 2008502127 A JP2008502127 A JP 2008502127A JP 2008536488 A5 JP2008536488 A5 JP 2008536488A5
- Authority
- JP
- Japan
- Prior art keywords
- probe set
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- kit
- expression
- Prior art date
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- 239000000523 sample Substances 0.000 claims description 102
- 108090000623 proteins and genes Proteins 0.000 claims description 23
- 238000000034 method Methods 0.000 claims description 12
- 102100027849 Homeobox protein GBX-2 Human genes 0.000 claims description 9
- 101000859754 Homo sapiens Homeobox protein GBX-2 Proteins 0.000 claims description 9
- 239000002299 complementary DNA Substances 0.000 claims description 3
- 230000014509 gene expression Effects 0.000 claims 22
- 102100036817 Ankyrin-3 Human genes 0.000 claims 13
- 102100023600 Fibroblast growth factor receptor 2 Human genes 0.000 claims 13
- 101710182389 Fibroblast growth factor receptor 2 Proteins 0.000 claims 13
- 101000928342 Homo sapiens Ankyrin-3 Proteins 0.000 claims 13
- 101000938676 Homo sapiens Liver carboxylesterase 1 Proteins 0.000 claims 13
- 101000945496 Homo sapiens Proliferation marker protein Ki-67 Proteins 0.000 claims 13
- 102100031347 Metallothionein-2 Human genes 0.000 claims 13
- 102100034836 Proliferation marker protein Ki-67 Human genes 0.000 claims 13
- 102100032340 G2/mitotic-specific cyclin-B1 Human genes 0.000 claims 11
- 101000868643 Homo sapiens G2/mitotic-specific cyclin-B1 Proteins 0.000 claims 11
- 101000896657 Homo sapiens Mitotic checkpoint serine/threonine-protein kinase BUB1 Proteins 0.000 claims 11
- 102100021691 Mitotic checkpoint serine/threonine-protein kinase BUB1 Human genes 0.000 claims 11
- 102100037964 E3 ubiquitin-protein ligase RING2 Human genes 0.000 claims 8
- 101001095815 Homo sapiens E3 ubiquitin-protein ligase RING2 Proteins 0.000 claims 8
- 101001112162 Homo sapiens Kinetochore protein NDC80 homolog Proteins 0.000 claims 8
- 101000807524 Homo sapiens Ubiquitin carboxyl-terminal hydrolase 22 Proteins 0.000 claims 8
- 102000018726 Host Cell Factor C1 Human genes 0.000 claims 8
- 108010027310 Host Cell Factor C1 Proteins 0.000 claims 8
- 102100023890 Kinetochore protein NDC80 homolog Human genes 0.000 claims 8
- 102100037184 Ubiquitin carboxyl-terminal hydrolase 22 Human genes 0.000 claims 8
- 238000005259 measurement Methods 0.000 claims 7
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 230000001394 metastastic effect Effects 0.000 claims 3
- 206010061289 metastatic neoplasm Diseases 0.000 claims 3
- 210000004881 tumor cell Anatomy 0.000 claims 3
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000032612 Glial tumor Diseases 0.000 claims 1
- 206010018338 Glioma Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 1
- 208000000172 Medulloblastoma Diseases 0.000 claims 1
- 206010027406 Mesothelioma Diseases 0.000 claims 1
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010066901 Treatment failure Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 210000001428 peripheral nervous system Anatomy 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 238000011471 prostatectomy Methods 0.000 claims 1
- 238000002271 resection Methods 0.000 claims 1
- 210000001625 seminal vesicle Anatomy 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 201000010653 vesiculitis Diseases 0.000 claims 1
- 241000282414 Homo sapiens Species 0.000 description 5
- 125000003275 alpha amino acid group Chemical group 0.000 description 4
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 101150000874 11 gene Proteins 0.000 description 1
- SOBMVBSSEJZEBX-UHFFFAOYSA-N 2-[2,2-bis(2-octadecanoyloxyethoxymethyl)butoxy]ethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCC(CC)(COCCOC(=O)CCCCCCCCCCCCCCCCC)COCCOC(=O)CCCCCCCCCCCCCCCCC SOBMVBSSEJZEBX-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66301405P | 2005-03-16 | 2005-03-16 | |
| PCT/US2006/009870 WO2006110264A2 (en) | 2005-03-16 | 2006-03-16 | Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009061926A Division JP2009131278A (ja) | 2005-03-16 | 2009-03-13 | 遺伝子発現署名を使用する、癌による死亡および前立腺癌生存率を予測するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008536488A JP2008536488A (ja) | 2008-09-11 |
| JP2008536488A5 true JP2008536488A5 (enExample) | 2009-05-07 |
Family
ID=37087482
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008502127A Pending JP2008536488A (ja) | 2005-03-16 | 2006-03-16 | 遺伝子発現署名を使用する、癌による死亡および前立腺癌生存率を予測するための方法および組成物 |
| JP2009061926A Pending JP2009131278A (ja) | 2005-03-16 | 2009-03-13 | 遺伝子発現署名を使用する、癌による死亡および前立腺癌生存率を予測するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009061926A Pending JP2009131278A (ja) | 2005-03-16 | 2009-03-13 | 遺伝子発現署名を使用する、癌による死亡および前立腺癌生存率を予測するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8349555B2 (enExample) |
| EP (1) | EP1874471A4 (enExample) |
| JP (2) | JP2008536488A (enExample) |
| AU (1) | AU2006234897A1 (enExample) |
| WO (1) | WO2006110264A2 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130122504A1 (en) * | 2011-11-14 | 2013-05-16 | Lars Dyrskjot Andersen | Expression Levels of COL4A3BP and other Markers Correlating with Progression or Non-Progression of Bladder Cancer |
| JP5150855B2 (ja) * | 2005-07-29 | 2013-02-27 | オンコセラピー・サイエンス株式会社 | Ｃｄｃａ１−ｋｎｔｃ２複合体を標的とするスクリーニングおよびｎｓｃｌｃの治療方法 |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Inst Inc | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
| WO2008058018A2 (en) | 2006-11-02 | 2008-05-15 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| DE102007044919A1 (de) * | 2007-09-19 | 2009-04-02 | Hefter, Harald, Prof. Dr. med. Dr. rer. nat. | Verfahren zur Bestimmung von sekundärem Therapieversagen |
| JP5407018B2 (ja) * | 2007-12-28 | 2014-02-05 | 国立大学法人名古屋大学 | 肺腺癌患者の術後再発を予測するための方法及び組成物 |
| EP2806054A1 (en) * | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| US8227202B2 (en) | 2008-07-10 | 2012-07-24 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
| EP3075864A1 (en) * | 2008-10-14 | 2016-10-05 | Caris MPI, Inc. | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| JP5461959B2 (ja) * | 2008-10-31 | 2014-04-02 | 株式会社Ｄｎａチップ研究所 | 神経膠腫予後予測方法、およびそれに用いるキット |
| EP3181705A1 (en) * | 2008-11-12 | 2017-06-21 | Caris Life Sciences Switzerland Holdings GmbH | Methods and systems of using exosomes for determining phenotypes |
| WO2010134023A2 (en) * | 2009-05-20 | 2010-11-25 | Koninklijke Philips Electronics N.V. | Biomarkers based on sets of molecular signatures |
| CN103237901B (zh) | 2010-03-01 | 2016-08-03 | 卡里斯生命科学瑞士控股有限责任公司 | 用于治疗诊断的生物标志物 |
| CA2795776A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers for disease |
| MX338883B (es) * | 2010-07-27 | 2016-05-04 | Genomic Health Inc | Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata. |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| CA2856981A1 (en) * | 2011-11-23 | 2013-06-27 | Uti Limited Partnership | Expression signature for staging and prognosis of prostate, breast and leukemia cancers |
| WO2013090620A1 (en) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| SG11201404390WA (en) | 2012-01-31 | 2014-08-28 | Genomic Health Inc | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| ES2945036T3 (es) * | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| WO2014028907A1 (en) | 2012-08-16 | 2014-02-20 | The Trustees Of Columbia University In The City Of New York | Diagnostic markers of indolent prostate cancer |
| KR101993716B1 (ko) * | 2012-09-28 | 2019-06-27 | 삼성전자주식회사 | 카테고리별 진단 모델을 이용한 병변 진단 장치 및 방법 |
| US9687290B2 (en) | 2012-10-02 | 2017-06-27 | Covidien Lp | Energy-based medical devices |
| TWI658049B (zh) * | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Ｋｎｔｃ２胜肽及含此胜肽之疫苗 |
| US20160040212A1 (en) * | 2013-03-15 | 2016-02-11 | The Broad Institute, Inc. | Methods for the Detection of DNA-RNA Proximity in Vivo |
| CN110444289A (zh) * | 2013-06-28 | 2019-11-12 | 南托米克斯有限责任公司 | 用于诊断检测的识别的途径分析 |
| ES2923942T3 (es) | 2013-11-06 | 2022-10-03 | Us Health | Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión |
| GB201322034D0 (en) | 2013-12-12 | 2014-01-29 | Almac Diagnostics Ltd | Prostate cancer classification |
| FR3017955B1 (fr) * | 2014-02-27 | 2018-04-06 | Assistance Publique - Hopitaux De Paris | Biomarqueurs diagnostics de la cardiomyopathie du peripartum |
| WO2016036878A1 (en) * | 2014-09-02 | 2016-03-10 | Nodality, Inc. | Methods for diagnosis, prognosis and methods of treatment |
| TWI582240B (zh) * | 2015-05-19 | 2017-05-11 | 鄭鴻鈞 | 以基因體預後評估試劑組預測乳癌患者局部區域復發風險及放射治療有效性的方法、用途及裝置 |
| US11756655B2 (en) | 2015-10-09 | 2023-09-12 | Guardant Health, Inc. | Population based treatment recommender using cell free DNA |
| WO2017184861A1 (en) | 2016-04-20 | 2017-10-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Evaluation of mantle cell lymphoma and methods related thereto |
| JP6963009B2 (ja) | 2016-05-19 | 2021-11-05 | オンコスカー エルエルシーOncoscar Llc | 臨床的に難治性の悪性腫瘍の診断及び治療標的化の方法 |
| US11414708B2 (en) | 2016-08-24 | 2022-08-16 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| AU2018210695B2 (en) | 2017-01-20 | 2024-07-18 | The University Of British Columbia | Molecular subtyping, prognosis, and treatment of bladder cancer |
| US11873532B2 (en) | 2017-03-09 | 2024-01-16 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| WO2018205035A1 (en) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| EP3715476A1 (en) * | 2019-03-29 | 2020-09-30 | Centre National De La Recherche Scientifique | Prognosis method of cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218122B1 (en) * | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US6203987B1 (en) * | 1998-10-27 | 2001-03-20 | Rosetta Inpharmatics, Inc. | Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns |
| NL1014106C2 (nl) | 2000-01-18 | 2001-07-20 | Univ Amsterdam | Werkwijze voor het detecteren van een pathologische afwijking bij een cel, een antistof en een assay kit. |
| DK1410011T3 (da) * | 2001-06-18 | 2011-07-18 | Netherlands Cancer Inst | Diagnose og prognose for brystcancerpatienter |
| AU2002358279A1 (en) | 2001-12-21 | 2003-07-30 | Arcturus Engineering, Inc. | Biomarkers for breast cancer |
| EP1552293A4 (en) * | 2002-09-10 | 2006-12-06 | Guennadi V Glinskii | METHOD FOR SEGREGATION OF GENES AND CLASSIFICATION OF BIOLOGICAL SAMPLES |
| US20050208500A1 (en) * | 2003-03-04 | 2005-09-22 | Erlander Mark G | Signatures of ER status in breast cancer |
| US8065093B2 (en) * | 2004-10-06 | 2011-11-22 | Agency For Science, Technology, And Research | Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers |
| WO2006060646A2 (en) * | 2004-12-03 | 2006-06-08 | Board Of Regents, The University Of Texas System | Cell microarray for profiling of cellular phenotypes and gene function |
| US20090098538A1 (en) * | 2006-03-31 | 2009-04-16 | Glinsky Gennadi V | Prognostic and diagnostic method for disease therapy |
| CA2648021A1 (en) * | 2006-03-31 | 2007-10-11 | Ordway Research Institute, Inc. | Prognostic and diagnostic method for cancer therapy |
-
2006
- 2006-03-16 WO PCT/US2006/009870 patent/WO2006110264A2/en not_active Ceased
- 2006-03-16 US US11/908,775 patent/US8349555B2/en not_active Expired - Fee Related
- 2006-03-16 AU AU2006234897A patent/AU2006234897A1/en not_active Abandoned
- 2006-03-16 JP JP2008502127A patent/JP2008536488A/ja active Pending
- 2006-03-16 EP EP06748441A patent/EP1874471A4/en not_active Withdrawn
-
2009
- 2009-03-13 JP JP2009061926A patent/JP2009131278A/ja active Pending
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