JP2008534929A - Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法 - Google Patents

Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法 Download PDF

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Publication number
JP2008534929A
JP2008534929A JP2008503231A JP2008503231A JP2008534929A JP 2008534929 A JP2008534929 A JP 2008534929A JP 2008503231 A JP2008503231 A JP 2008503231A JP 2008503231 A JP2008503231 A JP 2008503231A JP 2008534929 A JP2008534929 A JP 2008534929A
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Prior art keywords
image
path
image processing
phase
sample
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JP2008534929A5 (https=
Inventor
ポペスク，ガブリエル
ダサリ，ラマチヤンドラ
フエルド，ミヒヤエル
イケダ，タカヒロ
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
    • H10F39/00—Integrated devices, or assemblies of multiple devices, comprising at least one element covered by group H10F30/00, e.g. radiation detectors comprising photodiode arrays
    • H10F39/80—Constructional details of image sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453—Holographic interferometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1447—Spatial selection
    • G01N2015/145—Spatial selection by pattern of light, e.g. fringe pattern
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1454—Optical arrangements using phase shift or interference, e.g. for improving contrast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Medicinal Chemistry (AREA)
  • Signal Processing (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Microscoopes, Condenser (AREA)
  • Instruments For Measurement Of Length By Optical Means (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2008503231A 2005-03-25 2006-03-24 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法 Pending JP2008534929A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66511805P 2005-03-25 2005-03-25
PCT/US2006/010821 WO2006104899A2 (en) 2005-03-25 2006-03-24 System and method for hilbert phase imaging

Related Child Applications (1)

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JP2012093061A Division JP2012211902A (ja) 2005-03-25 2012-04-16 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法

Publications (2)

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JP2008534929A true JP2008534929A (ja) 2008-08-28
JP2008534929A5 JP2008534929A5 (https=) 2009-05-14

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JP2008503231A Pending JP2008534929A (ja) 2005-03-25 2006-03-24 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法
JP2012093061A Pending JP2012211902A (ja) 2005-03-25 2012-04-16 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法
JP2015209575A Expired - Lifetime JP6130464B2 (ja) 2005-03-25 2015-10-26 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法

Family Applications After (2)

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JP2012093061A Pending JP2012211902A (ja) 2005-03-25 2012-04-16 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法
JP2015209575A Expired - Lifetime JP6130464B2 (ja) 2005-03-25 2015-10-26 Ｈｉｌｂｅｒｔ位相画像処理のためのシステムと方法

Country Status (5)

Country Link
US (2) US8772693B2 (https=)
EP (2) EP1864112B1 (https=)
JP (3) JP2008534929A (https=)
CN (2) CN102539382B (https=)
WO (1) WO2006104899A2 (https=)

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JP2015534134A (ja) * 2012-10-29 2015-11-26 ゼネラル・エレクトリック・カンパニイ 標識を伴わない高コントラスト細胞撮像のための定量位相顕微鏡検査
JP2017529574A (ja) * 2014-09-22 2017-10-05 ナノライブ・エスエイＮａｎｏｌｉｖｅ ＳＡ 顕微鏡
JP2018105875A (ja) * 2011-01-25 2018-07-05 マサチューセッツ インスティテュート オブ テクノロジー 軸外し反射位相顕微鏡システムおよび軸外し位相顕微鏡のための方法
WO2019097587A1 (ja) * 2017-11-14 2019-05-23 株式会社ニコン 定量位相画像生成方法、定量位相画像生成装置およびプログラム

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JP6801846B2 (ja) 2013-02-05 2020-12-16 マサチューセッツ インスティテュート オブ テクノロジー ３ｄホログラフィックイメージングフローサイトメトリ
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KR20170096719A (ko) 2016-02-17 2017-08-25 한국전자통신연구원 이미지 처리 장치 및 그 처리 방법
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WO2018235476A1 (ja) * 2017-06-22 2018-12-27 ソニー株式会社 情報処理装置、情報処理方法、及びプログラム
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JP2018105875A (ja) * 2011-01-25 2018-07-05 マサチューセッツ インスティテュート オブ テクノロジー 軸外し反射位相顕微鏡システムおよび軸外し位相顕微鏡のための方法
US10451402B2 (en) 2011-01-25 2019-10-22 Massachusetts Institute Of Technology Single shot full-field reflection phase microscopy
JP2015534134A (ja) * 2012-10-29 2015-11-26 ゼネラル・エレクトリック・カンパニイ 標識を伴わない高コントラスト細胞撮像のための定量位相顕微鏡検査
JP2017529574A (ja) * 2014-09-22 2017-10-05 ナノライブ・エスエイＮａｎｏｌｉｖｅ ＳＡ 顕微鏡
WO2019097587A1 (ja) * 2017-11-14 2019-05-23 株式会社ニコン 定量位相画像生成方法、定量位相画像生成装置およびプログラム
JPWO2019097587A1 (ja) * 2017-11-14 2020-10-22 株式会社ニコン 定量位相画像生成方法、定量位相画像生成装置およびプログラム

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US20060291712A1 (en) 2006-12-28
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