JP2008531719A - Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 - Google Patents

Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 Download PDF

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Publication number
JP2008531719A
JP2008531719A JP2007558223A JP2007558223A JP2008531719A JP 2008531719 A JP2008531719 A JP 2008531719A JP 2007558223 A JP2007558223 A JP 2007558223A JP 2007558223 A JP2007558223 A JP 2007558223A JP 2008531719 A JP2008531719 A JP 2008531719A
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JP
Japan
Prior art keywords
antibody
seq
antigen
amino acids
kim
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Withdrawn
Application number
JP2007558223A
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English (en)
Japanese (ja)
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JP2008531719A5 (cg-RX-API-DMAC10.html
Inventor
ポール ディー． レナート，
パトリシア マックーン，
ベロニク ベイリー，
アレクセイ ルゴフスコイ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Biogen MA Inc
Original Assignee
Biogen Inc
Biogen Idec Inc
Biogen Idec MA Inc
Biogen MA Inc
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Application filed by Biogen Inc, Biogen Idec Inc, Biogen Idec MA Inc, Biogen MA Inc filed Critical Biogen Inc
Publication of JP2008531719A publication Critical patent/JP2008531719A/ja
Publication of JP2008531719A5 publication Critical patent/JP2008531719A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2007558223A 2005-03-02 2006-03-02 Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体 Withdrawn JP2008531719A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65778905P 2005-03-02 2005-03-02
PCT/US2006/007441 WO2006094134A2 (en) 2005-03-02 2006-03-02 Kim-1 antibodies for treatment of th2-mediated conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012073852A Division JP2012131825A (ja) 2005-03-02 2012-03-28 Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体

Publications (2)

Publication Number Publication Date
JP2008531719A true JP2008531719A (ja) 2008-08-14
JP2008531719A5 JP2008531719A5 (cg-RX-API-DMAC10.html) 2009-03-26

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JP2007558223A Withdrawn JP2008531719A (ja) 2005-03-02 2006-03-02 Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体
JP2012073852A Pending JP2012131825A (ja) 2005-03-02 2012-03-28 Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体

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JP2012073852A Pending JP2012131825A (ja) 2005-03-02 2012-03-28 Ｔｈ２介在性状態の治療のためのＫＩＭ−１抗体

Country Status (14)

Country Link
US (2) US8206705B2 (cg-RX-API-DMAC10.html)
EP (2) EP1865985B1 (cg-RX-API-DMAC10.html)
JP (2) JP2008531719A (cg-RX-API-DMAC10.html)
KR (1) KR101213894B1 (cg-RX-API-DMAC10.html)
CN (2) CN101166542A (cg-RX-API-DMAC10.html)
AT (1) ATE478707T1 (cg-RX-API-DMAC10.html)
AU (2) AU2006218489B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0608254A2 (cg-RX-API-DMAC10.html)
CA (1) CA2599967C (cg-RX-API-DMAC10.html)
DE (1) DE602006016413D1 (cg-RX-API-DMAC10.html)
IL (1) IL185653A (cg-RX-API-DMAC10.html)
NZ (1) NZ562045A (cg-RX-API-DMAC10.html)
WO (1) WO2006094134A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200708372B (cg-RX-API-DMAC10.html)

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WO2008064031A2 (en) * 2006-11-13 2008-05-29 Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses
EP2699256B1 (en) 2011-04-21 2017-09-27 The Regents of the University of Colorado, a body corporate Compositions and methods for the treatment of neuromyelitis optica
WO2017075537A1 (en) 2015-10-30 2017-05-04 Aleta Biotherapeutics Inc. Compositions and methods for treatment of cancer
MA43134A (fr) 2015-10-30 2018-09-05 Aleta Biotherapeutics Inc Compositions et méthodes de transduction tumorale

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WO2004084823A2 (en) * 2003-03-19 2004-10-07 Abgenix, Inc. Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof
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Also Published As

Publication number Publication date
EP1865985A2 (en) 2007-12-19
AU2011202405B2 (en) 2013-03-28
AU2006218489B2 (en) 2011-02-24
DE602006016413D1 (de) 2010-10-07
US8206705B2 (en) 2012-06-26
US20130089539A1 (en) 2013-04-11
WO2006094134A3 (en) 2006-10-19
AU2011202405A1 (en) 2011-06-09
KR20070110411A (ko) 2007-11-16
BRPI0608254A2 (pt) 2009-12-08
NZ562045A (en) 2010-12-24
CA2599967A1 (en) 2006-09-08
AU2006218489A1 (en) 2006-09-08
WO2006094134A2 (en) 2006-09-08
KR101213894B1 (ko) 2012-12-20
HK1118007A1 (en) 2009-01-30
ZA200708372B (en) 2008-12-31
JP2012131825A (ja) 2012-07-12
EP2251037B1 (en) 2015-01-14
IL185653A (en) 2013-04-30
ATE478707T1 (de) 2010-09-15
CN101166542A (zh) 2008-04-23
US20100150905A1 (en) 2010-06-17
CA2599967C (en) 2014-10-21
IL185653A0 (en) 2008-01-06
EP2251037A1 (en) 2010-11-17
EP1865985B1 (en) 2010-08-25
CN103751780A (zh) 2014-04-30

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