AU2006218489B2 - KIM-1 antibodies for treatment of Th2-mediated conditions - Google Patents

KIM-1 antibodies for treatment of Th2-mediated conditions Download PDF

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Publication number
AU2006218489B2
AU2006218489B2 AU2006218489A AU2006218489A AU2006218489B2 AU 2006218489 B2 AU2006218489 B2 AU 2006218489B2 AU 2006218489 A AU2006218489 A AU 2006218489A AU 2006218489 A AU2006218489 A AU 2006218489A AU 2006218489 B2 AU2006218489 B2 AU 2006218489B2
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AU
Australia
Prior art keywords
antibody
seq
antigen
amino acids
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006218489A
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English (en)
Other versions
AU2006218489A1 (en
Inventor
Veronique Bailly
Alexey Lugovskoy
Patricia Mccoon
Paul D. Rennert
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Biogen MA Inc
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Biogen MA Inc
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Filing date
Publication date
Application filed by Biogen MA Inc filed Critical Biogen MA Inc
Publication of AU2006218489A1 publication Critical patent/AU2006218489A1/en
Application granted granted Critical
Publication of AU2006218489B2 publication Critical patent/AU2006218489B2/en
Priority to AU2011202405A priority Critical patent/AU2011202405B2/en
Assigned to BIOGEN MA INC. reassignment BIOGEN MA INC. Request to Amend Deed and Register Assignors: BIOGEN IDEC MA INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2006218489A 2005-03-02 2006-03-02 KIM-1 antibodies for treatment of Th2-mediated conditions Ceased AU2006218489B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011202405A AU2011202405B2 (en) 2005-03-02 2011-05-24 KIM-1 Antibodies for Treatment of TH2-mediated Conditions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65778905P 2005-03-02 2005-03-02
US60/657,789 2005-03-02
PCT/US2006/007441 WO2006094134A2 (en) 2005-03-02 2006-03-02 Kim-1 antibodies for treatment of th2-mediated conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2011202405A Division AU2011202405B2 (en) 2005-03-02 2011-05-24 KIM-1 Antibodies for Treatment of TH2-mediated Conditions

Publications (2)

Publication Number Publication Date
AU2006218489A1 AU2006218489A1 (en) 2006-09-08
AU2006218489B2 true AU2006218489B2 (en) 2011-02-24

Family

ID=36648475

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2006218489A Ceased AU2006218489B2 (en) 2005-03-02 2006-03-02 KIM-1 antibodies for treatment of Th2-mediated conditions
AU2011202405A Ceased AU2011202405B2 (en) 2005-03-02 2011-05-24 KIM-1 Antibodies for Treatment of TH2-mediated Conditions

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2011202405A Ceased AU2011202405B2 (en) 2005-03-02 2011-05-24 KIM-1 Antibodies for Treatment of TH2-mediated Conditions

Country Status (14)

Country Link
US (2) US8206705B2 (cg-RX-API-DMAC10.html)
EP (2) EP1865985B1 (cg-RX-API-DMAC10.html)
JP (2) JP2008531719A (cg-RX-API-DMAC10.html)
KR (1) KR101213894B1 (cg-RX-API-DMAC10.html)
CN (2) CN101166542A (cg-RX-API-DMAC10.html)
AT (1) ATE478707T1 (cg-RX-API-DMAC10.html)
AU (2) AU2006218489B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0608254A2 (cg-RX-API-DMAC10.html)
CA (1) CA2599967C (cg-RX-API-DMAC10.html)
DE (1) DE602006016413D1 (cg-RX-API-DMAC10.html)
IL (1) IL185653A (cg-RX-API-DMAC10.html)
NZ (1) NZ562045A (cg-RX-API-DMAC10.html)
WO (1) WO2006094134A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200708372B (cg-RX-API-DMAC10.html)

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Publication number Priority date Publication date Assignee Title
WO2008064031A2 (en) * 2006-11-13 2008-05-29 Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses
EP2699256B1 (en) 2011-04-21 2017-09-27 The Regents of the University of Colorado, a body corporate Compositions and methods for the treatment of neuromyelitis optica
WO2017075537A1 (en) 2015-10-30 2017-05-04 Aleta Biotherapeutics Inc. Compositions and methods for treatment of cancer
MA43134A (fr) 2015-10-30 2018-09-05 Aleta Biotherapeutics Inc Compositions et méthodes de transduction tumorale

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2002098920A1 (en) * 2001-06-01 2002-12-12 Biogen, Inc. Molecules and methods for inhibiting shedding of kim-1
WO2004060041A2 (en) * 2002-12-30 2004-07-22 Biogen Idec Ma Inc. Kim-1 antagonists and use to modulate immune system
WO2004084823A2 (en) * 2003-03-19 2004-10-07 Abgenix, Inc. Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof

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WO2002098920A1 (en) * 2001-06-01 2002-12-12 Biogen, Inc. Molecules and methods for inhibiting shedding of kim-1
WO2004060041A2 (en) * 2002-12-30 2004-07-22 Biogen Idec Ma Inc. Kim-1 antagonists and use to modulate immune system
WO2004084823A2 (en) * 2003-03-19 2004-10-07 Abgenix, Inc. Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof

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Also Published As

Publication number Publication date
EP1865985A2 (en) 2007-12-19
AU2011202405B2 (en) 2013-03-28
DE602006016413D1 (de) 2010-10-07
US8206705B2 (en) 2012-06-26
US20130089539A1 (en) 2013-04-11
WO2006094134A3 (en) 2006-10-19
AU2011202405A1 (en) 2011-06-09
KR20070110411A (ko) 2007-11-16
BRPI0608254A2 (pt) 2009-12-08
NZ562045A (en) 2010-12-24
CA2599967A1 (en) 2006-09-08
AU2006218489A1 (en) 2006-09-08
WO2006094134A2 (en) 2006-09-08
KR101213894B1 (ko) 2012-12-20
HK1118007A1 (en) 2009-01-30
ZA200708372B (en) 2008-12-31
JP2012131825A (ja) 2012-07-12
EP2251037B1 (en) 2015-01-14
IL185653A (en) 2013-04-30
ATE478707T1 (de) 2010-09-15
JP2008531719A (ja) 2008-08-14
CN101166542A (zh) 2008-04-23
US20100150905A1 (en) 2010-06-17
CA2599967C (en) 2014-10-21
IL185653A0 (en) 2008-01-06
EP2251037A1 (en) 2010-11-17
EP1865985B1 (en) 2010-08-25
CN103751780A (zh) 2014-04-30

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired