BRPI0608254A2 - anticorpos kim-1 para o tratamento de condições mediadas por th2 - Google Patents
anticorpos kim-1 para o tratamento de condições mediadas por th2Info
- Publication number
- BRPI0608254A2 BRPI0608254A2 BRPI0608254-8A BRPI0608254A BRPI0608254A2 BR PI0608254 A2 BRPI0608254 A2 BR PI0608254A2 BR PI0608254 A BRPI0608254 A BR PI0608254A BR PI0608254 A2 BRPI0608254 A2 BR PI0608254A2
- Authority
- BR
- Brazil
- Prior art keywords
- kim
- antibodies
- treatment
- mediated conditions
- mediated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65778905P | 2005-03-02 | 2005-03-02 | |
| PCT/US2006/007441 WO2006094134A2 (en) | 2005-03-02 | 2006-03-02 | Kim-1 antibodies for treatment of th2-mediated conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0608254A2 true BRPI0608254A2 (pt) | 2009-12-08 |
Family
ID=36648475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0608254-8A BRPI0608254A2 (pt) | 2005-03-02 | 2006-03-02 | anticorpos kim-1 para o tratamento de condições mediadas por th2 |
Country Status (14)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008064031A2 (en) * | 2006-11-13 | 2008-05-29 | Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services | Potent activation of antigen presenting cells by the hepatitis a virus cellular receptor 1 and its role in the regulation of immune responses |
| EP2699256B1 (en) | 2011-04-21 | 2017-09-27 | The Regents of the University of Colorado, a body corporate | Compositions and methods for the treatment of neuromyelitis optica |
| WO2017075537A1 (en) | 2015-10-30 | 2017-05-04 | Aleta Biotherapeutics Inc. | Compositions and methods for treatment of cancer |
| MA43134A (fr) | 2015-10-30 | 2018-09-05 | Aleta Biotherapeutics Inc | Compositions et méthodes de transduction tumorale |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| SG44845A1 (en) | 1993-01-12 | 1997-12-19 | Biogen Inc | Recombitant anti-vla4 antibody molecules |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| US5622861A (en) | 1994-08-05 | 1997-04-22 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA encoding hepatitis A virus receptor |
| US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE19541844C1 (de) | 1995-11-09 | 1997-07-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von menschlichen Antikörpern und deren Verwendung |
| US6165733A (en) | 1996-05-23 | 2000-12-26 | Chiron Corporation | γ II adaptin |
| JP4602482B2 (ja) * | 1996-05-24 | 2010-12-22 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 組織再生のモジュレーター |
| JP2001503271A (ja) | 1996-11-01 | 2001-03-13 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | ヒト粘膜アドレシン細胞接着分子―1(MAdCAM―1)およびそのスプライス変異体 |
| EP1972194A1 (en) | 1996-12-03 | 2008-09-24 | Amgen Fremont Inc. | Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom |
| JP4094066B2 (ja) | 1996-12-06 | 2008-06-04 | バーテックス ファーマシューティカルズ インコーポレイテッド | インターロイキン−1β変換酵素のインヒビター |
| KR100764256B1 (ko) | 1998-01-23 | 2007-10-05 | 에프. 호프만-라 로슈 아게 | 인간 인터루킨-12에 대한 항체 |
| CN1160075C (zh) | 1998-03-11 | 2004-08-04 | 卫福有限公司 | 杂环酰胺化合物在制备IgE抗体产生抑制剂中的用途 |
| US6228642B1 (en) | 1998-10-05 | 2001-05-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression |
| US8288322B2 (en) | 2000-04-17 | 2012-10-16 | Dyax Corp. | Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries |
| JP2004500879A (ja) * | 2000-06-16 | 2004-01-15 | バイオジェン インコーポレイテッド | 腎の調節エレメントおよびそれらの使用方法 |
| DK1401869T3 (da) * | 2001-06-01 | 2008-04-28 | Biogen Idec Inc | Molekyler og fremgangsmåder til inhibering af udskillkelse af kim 1 |
| JP4572276B2 (ja) * | 2001-06-29 | 2010-11-04 | ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニヴァーシティ | T細胞調節遺伝子およびその使用方法 |
| US7838220B2 (en) * | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
| CA2459219A1 (en) | 2001-09-17 | 2003-03-27 | Protein Design Labs, Inc. | Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer |
| WO2003042661A2 (en) | 2001-11-13 | 2003-05-22 | Protein Design Labs, Inc. | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
| US7687454B2 (en) * | 2001-12-03 | 2010-03-30 | The University Of British Columbia | Effectors of innate immunity determination |
| JP4694128B2 (ja) * | 2002-01-30 | 2011-06-08 | ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド | TIM−3、Th1特異的細胞表面分子に関連した組成物および方法 |
| AU2003228336B2 (en) * | 2002-03-19 | 2009-07-30 | Curagen Corporation | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| GB0215509D0 (en) | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
| CA2512138C (en) * | 2002-12-30 | 2013-07-16 | Biogen Idec Ma Inc. | Kim-1 antagonists and use to modulate immune system |
| CA2519528C (en) | 2003-03-19 | 2016-01-26 | Abgenix, Inc. | Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof |
| US20050119210A1 (en) | 2003-05-20 | 2005-06-02 | Xiaobing Be | Compositions and methods for diagnosing and treating cancers |
| TW200539890A (en) * | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| BRPI0509139A (pt) * | 2004-03-24 | 2007-08-28 | Telos Fharmaceuticals Inc | composição, e, método de estimulação de uma resposta imune em um indivìduo, de tratamento profilático de uma doença, de melhoramento de um sinal ou sintoma associado com uma doença, de alvejamento de um tumor, de inibição do crescimento de tumor, e de detecção de um tumor |
| US8025557B2 (en) | 2009-02-27 | 2011-09-27 | Illinois Tool Works Inc. | Sanding clay |
-
2006
- 2006-03-02 EP EP06736714A patent/EP1865985B1/en not_active Expired - Lifetime
- 2006-03-02 NZ NZ562045A patent/NZ562045A/en not_active IP Right Cessation
- 2006-03-02 US US11/817,638 patent/US8206705B2/en not_active Expired - Fee Related
- 2006-03-02 CA CA2599967A patent/CA2599967C/en not_active Expired - Fee Related
- 2006-03-02 BR BRPI0608254-8A patent/BRPI0608254A2/pt not_active IP Right Cessation
- 2006-03-02 AU AU2006218489A patent/AU2006218489B2/en not_active Ceased
- 2006-03-02 DE DE602006016413T patent/DE602006016413D1/de not_active Expired - Lifetime
- 2006-03-02 WO PCT/US2006/007441 patent/WO2006094134A2/en not_active Ceased
- 2006-03-02 KR KR1020077022608A patent/KR101213894B1/ko not_active Expired - Fee Related
- 2006-03-02 CN CNA2006800139893A patent/CN101166542A/zh active Pending
- 2006-03-02 AT AT06736714T patent/ATE478707T1/de not_active IP Right Cessation
- 2006-03-02 EP EP10173620.5A patent/EP2251037B1/en not_active Expired - Lifetime
- 2006-03-02 CN CN201410043208.1A patent/CN103751780A/zh active Pending
- 2006-03-02 JP JP2007558223A patent/JP2008531719A/ja not_active Withdrawn
-
2007
- 2007-09-02 IL IL185653A patent/IL185653A/en not_active IP Right Cessation
- 2007-10-01 ZA ZA200708372A patent/ZA200708372B/xx unknown
-
2011
- 2011-05-24 AU AU2011202405A patent/AU2011202405B2/en not_active Ceased
-
2012
- 2012-03-28 JP JP2012073852A patent/JP2012131825A/ja active Pending
- 2012-04-04 US US13/439,413 patent/US20130089539A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1865985A2 (en) | 2007-12-19 |
| AU2011202405B2 (en) | 2013-03-28 |
| AU2006218489B2 (en) | 2011-02-24 |
| DE602006016413D1 (de) | 2010-10-07 |
| US8206705B2 (en) | 2012-06-26 |
| US20130089539A1 (en) | 2013-04-11 |
| WO2006094134A3 (en) | 2006-10-19 |
| AU2011202405A1 (en) | 2011-06-09 |
| KR20070110411A (ko) | 2007-11-16 |
| NZ562045A (en) | 2010-12-24 |
| CA2599967A1 (en) | 2006-09-08 |
| AU2006218489A1 (en) | 2006-09-08 |
| WO2006094134A2 (en) | 2006-09-08 |
| KR101213894B1 (ko) | 2012-12-20 |
| HK1118007A1 (en) | 2009-01-30 |
| ZA200708372B (en) | 2008-12-31 |
| JP2012131825A (ja) | 2012-07-12 |
| EP2251037B1 (en) | 2015-01-14 |
| IL185653A (en) | 2013-04-30 |
| ATE478707T1 (de) | 2010-09-15 |
| JP2008531719A (ja) | 2008-08-14 |
| CN101166542A (zh) | 2008-04-23 |
| US20100150905A1 (en) | 2010-06-17 |
| CA2599967C (en) | 2014-10-21 |
| IL185653A0 (en) | 2008-01-06 |
| EP2251037A1 (en) | 2010-11-17 |
| EP1865985B1 (en) | 2010-08-25 |
| CN103751780A (zh) | 2014-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B25D | Requested change of name of applicant approved |
Owner name: BIOGEN MA INC. (US) |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: C07K 16/28 (2006.01), A61P 11/06 (2006.01), A61P 3 |