JP2008530582A5 - - Google Patents
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- Publication number
- JP2008530582A5 JP2008530582A5 JP2007556362A JP2007556362A JP2008530582A5 JP 2008530582 A5 JP2008530582 A5 JP 2008530582A5 JP 2007556362 A JP2007556362 A JP 2007556362A JP 2007556362 A JP2007556362 A JP 2007556362A JP 2008530582 A5 JP2008530582 A5 JP 2008530582A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cyr61
- level
- antibody
- urine sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101150042405 CCN1 gene Proteins 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 14
- 210000002700 urine Anatomy 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- 201000009030 Carcinoma Diseases 0.000 claims 2
- 208000005440 Basal Cell Neoplasms Diseases 0.000 claims 1
- 206010004146 Basal cell carcinoma Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 claims 1
- 206010062038 Lip neoplasm Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 208000009956 adenocarcinoma Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 1
- 201000006721 lip cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000002314 small intestine cancer Diseases 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65411105P | 2005-02-18 | 2005-02-18 | |
| US60/654,111 | 2005-02-18 | ||
| PCT/US2006/005812 WO2006089212A2 (en) | 2005-02-18 | 2006-02-17 | Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530582A JP2008530582A (ja) | 2008-08-07 |
| JP2008530582A5 true JP2008530582A5 (enExample) | 2009-04-16 |
| JP5006802B2 JP5006802B2 (ja) | 2012-08-22 |
Family
ID=36917123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556362A Expired - Fee Related JP5006802B2 (ja) | 2005-02-18 | 2006-02-17 | 上皮由来の癌診断および予後診断のためのバイオマーカーとしてのＣｙｒ６１ |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7858324B2 (enExample) |
| EP (1) | EP1849002A4 (enExample) |
| JP (1) | JP5006802B2 (enExample) |
| CN (1) | CN101120252A (enExample) |
| AU (1) | AU2006214105A1 (enExample) |
| CA (1) | CA2598217A1 (enExample) |
| WO (1) | WO2006089212A2 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10533998B2 (en) | 2008-07-18 | 2020-01-14 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| CN101120252A (zh) * | 2005-02-18 | 2008-02-06 | 儿童医疗中心有限公司 | 作为生物标记物用于上皮来源的癌症的诊断和预后的cyr61 |
| EP3913375A1 (en) | 2006-01-11 | 2021-11-24 | Bio-Rad Laboratories, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| EP2021113A2 (en) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| US9012390B2 (en) | 2006-08-07 | 2015-04-21 | Raindance Technologies, Inc. | Fluorocarbon emulsion stabilizing surfactants |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| EP2126577B1 (en) * | 2007-03-29 | 2013-03-13 | Fujirebio Diagnostics, Inc. | Use of he4 for assessment of breast cancers |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
| PL2733492T3 (pl) | 2008-08-05 | 2016-08-31 | Toray Industries | Sposób wykrywania nowotworów |
| AU2009278386B2 (en) | 2008-08-05 | 2015-05-21 | Toray Industries, Inc. | Pharmaceutical composition for treatment and prevention of cancers |
| CN101747435B (zh) * | 2008-12-18 | 2013-06-19 | 上海市免疫学研究所 | 一种中和cyr61的单克隆抗体(杂交瘤)及其应用 |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2273272A1 (en) | 2009-07-06 | 2011-01-12 | Stichting Katholieke Universiteit | Method for predicting the outcome of chemotherapy in ovarian cancer |
| WO2011042564A1 (en) | 2009-10-09 | 2011-04-14 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| EP2517025B1 (en) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Methods for reducing the exchange of molecules between droplets |
| RU2567657C2 (ru) | 2010-02-04 | 2015-11-10 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| RU2598258C2 (ru) | 2010-02-04 | 2016-09-20 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| BR112012018943A8 (pt) | 2010-02-04 | 2017-12-19 | Toray Industries | medicamento e método para o tratamento e/ou prevenção de um câncer |
| MX340014B (es) | 2010-02-04 | 2016-06-22 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| CA2788718C (en) | 2010-02-04 | 2019-05-21 | Shinichi Kobayashi | Caprin-1 antibody for treating and/or preventing cancer |
| WO2011096533A1 (ja) | 2010-02-04 | 2011-08-11 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP4484577A3 (en) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| EP2622103B2 (en) | 2010-09-30 | 2022-11-16 | Bio-Rad Laboratories, Inc. | Sandwich assays in droplets |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP2721410A4 (en) * | 2011-06-16 | 2015-01-14 | Giovanni M Pitari | BIOMARKERS FOR THE DIAGNOSIS AND TREATMENT OF EPITHELIAL CANCER |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| CN103764825B (zh) | 2011-08-04 | 2015-09-02 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| CA2844038C (en) | 2011-08-04 | 2019-05-07 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| EP2740798B1 (en) | 2011-08-04 | 2016-12-07 | Toray Industries, Inc. | Cancer treatment and/or prevention drug composition |
| CA2844042C (en) | 2011-08-04 | 2019-06-18 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| CN103717739B (zh) | 2011-08-04 | 2015-07-29 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| CA2844033C (en) | 2011-08-04 | 2021-07-27 | Toray Industries, Inc. | Method for detecting pancreatic cancer |
| CN103717238B (zh) | 2011-08-04 | 2016-10-12 | 东丽株式会社 | 胰癌的治疗和/或预防用药物组合物 |
| WO2013120089A1 (en) | 2012-02-10 | 2013-08-15 | Raindance Technologies, Inc. | Molecular diagnostic screening assay |
| AU2013223147B2 (en) | 2012-02-21 | 2017-10-05 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| WO2013125654A1 (ja) | 2012-02-21 | 2013-08-29 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| PT2818481T (pt) | 2012-02-21 | 2019-10-25 | Toray Industries | Composição farmacêutica para tratamento e/ou prevenção de cancro |
| MX360208B (es) | 2012-02-21 | 2018-10-24 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| EP2832365B1 (en) | 2012-03-30 | 2017-11-01 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of liver cancer |
| JP6107655B2 (ja) | 2012-03-30 | 2017-04-05 | 東レ株式会社 | 胆嚢癌の治療及び／又は予防用医薬組成物 |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| PT2876446T (pt) | 2012-07-19 | 2019-03-25 | Toray Industries | Método para deteção de cancro |
| RU2646464C2 (ru) | 2012-07-19 | 2018-03-05 | Торэй Индастриз, Инк. | Метод детекции рака |
| EP2986762B1 (en) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| PT3031826T (pt) | 2013-08-09 | 2019-01-18 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| US11193176B2 (en) | 2013-12-31 | 2021-12-07 | Bio-Rad Laboratories, Inc. | Method for detecting and quantifying latent retroviral RNA species |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| CN105396136B (zh) * | 2015-11-23 | 2018-10-30 | 上海交通大学医学院附属第九人民医院 | CCN1（Cyr61）在治疗皮肤损伤及皮肤萎缩相关疾病中的应用 |
| CN107422125A (zh) * | 2016-05-23 | 2017-12-01 | 中国医学科学院肿瘤医院 | 与肌层浸润性膀胱癌相关的尿液蛋白质标志物 |
| EP3364190A1 (en) | 2017-02-20 | 2018-08-22 | Panka Cancer Research AG | Method of detecting cancer or cancer cells |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| CN108752454B (zh) * | 2018-06-19 | 2021-07-20 | 中山大学孙逸仙纪念医院 | 一种人CYR61蛋白Ser188位点磷酸化抗原、抗体及其制备方法和应用 |
| CN111426835A (zh) * | 2019-01-10 | 2020-07-17 | 北京师范大学 | 肝转移癌相关的尿液蛋白标记物的筛选及其用途 |
| CN113777315A (zh) * | 2020-06-09 | 2021-12-10 | 首都医科大学附属北京世纪坛医院 | 尿液泛素样蛋白isg15及其多肽片段在烧伤中的应用 |
| CN112147337B (zh) * | 2020-08-19 | 2024-05-28 | 德赛诊断系统(上海)有限公司 | 一种富含半胱氨酸蛋白61高敏化学发光检测试剂盒及其制备和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| US6355623B2 (en) * | 1998-09-24 | 2002-03-12 | Hopital-Sainte-Justine | Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage |
| US6335170B1 (en) * | 1999-02-22 | 2002-01-01 | Torben F. Orntoft | Gene expression in bladder tumors |
| US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| AU2001271365A1 (en) * | 2000-06-21 | 2002-01-02 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
| JP2004509909A (ja) * | 2000-09-29 | 2004-04-02 | ワイス | ヒトの子宮平滑筋腫の治療および診断におけるｃｙｒ６１の使用 |
| US20040086504A1 (en) * | 2001-06-21 | 2004-05-06 | Deepak Sampath | Cyr61 as a target for treatment and diagnosis of breast cancer |
| AU2002337657A1 (en) * | 2001-07-25 | 2003-02-17 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| AU2002326939A1 (en) | 2001-09-18 | 2003-04-01 | Fibrogen, Inc. | Methods of assaying connective tissue growth factor |
| JP2003177126A (ja) * | 2001-12-13 | 2003-06-27 | Kenichi Katsube | Ｃｃｎファミリー蛋白質活性制御剤のスクリーニング方法 |
| WO2003058201A2 (en) * | 2001-12-31 | 2003-07-17 | Quark Biotech, Inc. | Methods for identifying marker genes for cancer |
| EP2360475B1 (en) * | 2003-03-27 | 2019-10-02 | Children's Hospital Medical Center | A method and kit for detecting the early onset of renal tubular cell injury |
| JP2004315480A (ja) * | 2003-04-21 | 2004-11-11 | Yoshiyuki Kakehi | 前立腺疾患治療用医薬組成物 |
| CN101120252A (zh) * | 2005-02-18 | 2008-02-06 | 儿童医疗中心有限公司 | 作为生物标记物用于上皮来源的癌症的诊断和预后的cyr61 |
-
2006
- 2006-02-17 CN CNA2006800051581A patent/CN101120252A/zh active Pending
- 2006-02-17 CA CA002598217A patent/CA2598217A1/en not_active Abandoned
- 2006-02-17 JP JP2007556362A patent/JP5006802B2/ja not_active Expired - Fee Related
- 2006-02-17 EP EP06735465A patent/EP1849002A4/en not_active Ceased
- 2006-02-17 AU AU2006214105A patent/AU2006214105A1/en not_active Abandoned
- 2006-02-17 WO PCT/US2006/005812 patent/WO2006089212A2/en not_active Ceased
- 2006-02-17 US US11/815,831 patent/US7858324B2/en active Active
-
2010
- 2010-12-23 US US12/977,348 patent/US20110189700A1/en not_active Abandoned
-
2016
- 2016-08-29 US US15/249,829 patent/US20170205419A1/en not_active Abandoned
-
2018
- 2018-06-26 US US16/018,254 patent/US20190154693A1/en not_active Abandoned
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