JP2008529008A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008529008A5 JP2008529008A5 JP2007553289A JP2007553289A JP2008529008A5 JP 2008529008 A5 JP2008529008 A5 JP 2008529008A5 JP 2007553289 A JP2007553289 A JP 2007553289A JP 2007553289 A JP2007553289 A JP 2007553289A JP 2008529008 A5 JP2008529008 A5 JP 2008529008A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cystatin
- epithelial
- level
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010061635 Cystatin B Proteins 0.000 claims 23
- 102100026891 Cystatin-B Human genes 0.000 claims 23
- 201000009030 Carcinoma Diseases 0.000 claims 21
- 239000000107 tumor biomarker Substances 0.000 claims 21
- 238000000034 method Methods 0.000 claims 20
- 239000000523 sample Substances 0.000 claims 14
- 206010005003 Bladder cancer Diseases 0.000 claims 7
- 239000012472 biological sample Substances 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 239000013068 control sample Substances 0.000 claims 5
- 201000005112 urinary bladder cancer Diseases 0.000 claims 5
- 210000002700 urine Anatomy 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102100024341 10 kDa heat shock protein, mitochondrial Human genes 0.000 claims 2
- 108010059013 Chaperonin 10 Proteins 0.000 claims 2
- 102000011195 Profilin Human genes 0.000 claims 2
- 108050001408 Profilin Proteins 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 208000005440 Basal Cell Neoplasms Diseases 0.000 claims 1
- 206010004146 Basal cell carcinoma Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 claims 1
- 206010062038 Lip neoplasm Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 208000009956 adenocarcinoma Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 1
- 201000006721 lip cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000002314 small intestine cancer Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64811005P | 2005-01-28 | 2005-01-28 | |
| PCT/US2006/003049 WO2006081473A2 (en) | 2005-01-28 | 2006-01-30 | Methods for diagnosis and prognosis of epithelial cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008529008A JP2008529008A (ja) | 2008-07-31 |
| JP2008529008A5 true JP2008529008A5 (enExample) | 2009-03-19 |
Family
ID=36741098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007553289A Pending JP2008529008A (ja) | 2005-01-28 | 2006-01-30 | 上皮癌の診断および予後診断のための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8685659B2 (enExample) |
| EP (1) | EP1842065B1 (enExample) |
| JP (1) | JP2008529008A (enExample) |
| CN (1) | CN101268368A (enExample) |
| AT (1) | ATE490465T1 (enExample) |
| AU (1) | AU2006207954A1 (enExample) |
| CA (1) | CA2595377A1 (enExample) |
| DE (1) | DE602006018578D1 (enExample) |
| WO (1) | WO2006081473A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| EP1512970A1 (en) * | 2003-09-05 | 2005-03-09 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Method for determining the impact of a multicomponent mixture on the biological profile of a disease |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| CA2595377A1 (en) * | 2005-01-28 | 2006-08-03 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| EP2364774A3 (en) | 2006-01-11 | 2014-06-04 | Raindance Technologies, Inc. | Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| EP2021113A2 (en) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| EP2077912B1 (en) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| KR100767878B1 (ko) * | 2006-11-07 | 2007-10-17 | 전북대학교산학협력단 | 간세포암 진단용 조성물, 이를 포함하는 간세포암 진단키트 및 간세포암 진단방법 |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| WO2008103815A2 (en) * | 2007-02-23 | 2008-08-28 | Predictive Biosciences Corporation | Clinical intervention directed diagnostic methods |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| WO2009017475A1 (en) * | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| JP5120843B2 (ja) * | 2008-06-04 | 2013-01-16 | 国立大学法人山梨大学 | 自己免疫性膵炎の検査方法及び検査試薬 |
| EP4047367A1 (en) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Method for detecting target analytes with droplet libraries |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2486409A1 (en) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| WO2011079176A2 (en) | 2009-12-23 | 2011-06-30 | Raindance Technologies, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP3392349A1 (en) | 2010-02-12 | 2018-10-24 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US10436797B2 (en) * | 2010-06-03 | 2019-10-08 | Idexx Laboratories, Inc. | Markers for renal disease |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| US9364803B2 (en) | 2011-02-11 | 2016-06-14 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| EP3736281A1 (en) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Compositions and methods for molecular labeling |
| EP3709018A1 (en) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Microfluidic apparatus for identifying components of a chemical reaction |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| US20130115599A1 (en) * | 2011-11-08 | 2013-05-09 | Medical Diagnostic Laboratories, Llc | Increased cip2a expression and bladder cancer in humans |
| EP3495817B1 (en) | 2012-02-10 | 2024-10-16 | Bio-Rad Laboratories, Inc. | Molecular diagnostic screening assay |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| US10568869B2 (en) * | 2012-12-11 | 2020-02-25 | Cornell University | Methods for diagnosing and treating prostate cancer |
| WO2014172288A2 (en) | 2013-04-19 | 2014-10-23 | Raindance Technologies, Inc. | Digital analyte analysis |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10712349B2 (en) | 2014-04-15 | 2020-07-14 | The Brigham And Women's Hospital, Inc. | Circulating KIM-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| NZ745263A (en) * | 2016-03-02 | 2022-07-01 | Idexx Lab Inc | Methods and compositions for the detection and diagnosis of renal disease and periodontal disease |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| WO2022006514A1 (en) * | 2020-07-02 | 2022-01-06 | Gopath Laboratories Llc | Immune profiling and methods of using same to predict responsiveness to an immunotherapy and treat cancer |
| CN112379093B (zh) * | 2020-10-22 | 2023-06-16 | 上海良润生物医药科技有限公司 | CST-Cathepsin复合物作为肿瘤诊断标志物的应用 |
| CN119604763A (zh) * | 2022-01-26 | 2025-03-11 | 艾德克斯实验室公司 | 用于区分进展性慢性肾脏疾病与稳定性慢性肾脏疾病的方法和组合物 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| NZ267842A (en) | 1993-05-28 | 1997-09-22 | Baylor College Medicine | Apparatus for measuring molecular mass (by mass spectrometry) in which the sample is ionised on the sample holder and desorbed therefrom by laser pulses |
| US5702892A (en) | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| JP2001524802A (ja) | 1996-07-15 | 2001-12-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 20q13アンプリコンからの遺伝子及びそれらの使用 |
| JPH10262680A (ja) * | 1997-03-25 | 1998-10-06 | Kirin Brewery Co Ltd | Rho標的タンパク質ヒトmDiaおよびその遺伝子 |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6642007B1 (en) | 1998-11-02 | 2003-11-04 | Pfizer Inc. | Assays for measurement of type II collagen fragments in urine |
| US20030124543A1 (en) | 1999-01-15 | 2003-07-03 | Stuart Susan G. | Breast cancer marker |
| US6358683B1 (en) | 1999-06-03 | 2002-03-19 | The Regents Of The University Of California | Blood-based assays for breast cancer |
| US6939714B2 (en) * | 1999-06-18 | 2005-09-06 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
| WO2001018058A2 (en) | 1999-09-07 | 2001-03-15 | Viventia Biotech Inc. | Enhanced phage display library of human vh fragments and methods for producing same |
| US6998232B1 (en) | 1999-09-27 | 2006-02-14 | Quark Biotech, Inc. | Methods of diagnosing bladder cancer |
| US20040142361A1 (en) * | 1999-11-30 | 2004-07-22 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US7429466B2 (en) | 2000-01-24 | 2008-09-30 | Hypromatrix, Inc | Methods and arrays for detecting biological molecules |
| KR20030031911A (ko) | 2001-04-19 | 2003-04-23 | 싸이퍼젠 바이오시스템즈, 인코포레이티드 | 질량 분석법과 친화성 태그를 이용한 생물분자 특성화 |
| US7112408B2 (en) | 2001-06-08 | 2006-09-26 | The Brigham And Women's Hospital, Inc. | Detection of ovarian cancer based upon alpha-haptoglobin levels |
| US20040076955A1 (en) | 2001-07-03 | 2004-04-22 | Eos Biotechnology, Inc. | Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer |
| US20030013208A1 (en) | 2001-07-13 | 2003-01-16 | Milagen, Inc. | Information enhanced antibody arrays |
| JP2005500543A (ja) | 2001-08-13 | 2005-01-06 | ビヨンド ジェノミクス, インコーポレイテッド | 生物学的系をプロファイリングするための方法およびシステム |
| US20040009212A1 (en) | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| US20030157579A1 (en) * | 2002-02-14 | 2003-08-21 | Kalobios, Inc. | Molecular sensors activated by disinhibition |
| US20030199001A1 (en) | 2002-04-23 | 2003-10-23 | Pitt Aldo M. | Sample preparation of biological fluids for proteomic applications |
| US7191068B2 (en) | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
| US20070178090A1 (en) | 2003-04-01 | 2007-08-02 | Genzyme Corporation | Breast endothelial cell expression patterns |
| CA2595377A1 (en) * | 2005-01-28 | 2006-08-03 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| WO2009017475A1 (en) | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
-
2006
- 2006-01-30 CA CA002595377A patent/CA2595377A1/en not_active Abandoned
- 2006-01-30 AU AU2006207954A patent/AU2006207954A1/en not_active Abandoned
- 2006-01-30 US US11/814,939 patent/US8685659B2/en not_active Expired - Fee Related
- 2006-01-30 CN CNA2006800098728A patent/CN101268368A/zh active Pending
- 2006-01-30 WO PCT/US2006/003049 patent/WO2006081473A2/en not_active Ceased
- 2006-01-30 AT AT06719762T patent/ATE490465T1/de not_active IP Right Cessation
- 2006-01-30 JP JP2007553289A patent/JP2008529008A/ja active Pending
- 2006-01-30 EP EP06719762A patent/EP1842065B1/en not_active Not-in-force
- 2006-01-30 DE DE602006018578T patent/DE602006018578D1/de active Active
-
2007
- 2007-07-27 US US11/829,323 patent/US20080064047A1/en not_active Abandoned
-
2013
- 2013-04-17 US US13/864,707 patent/US20140106378A1/en not_active Abandoned
-
2014
- 2014-10-01 US US14/503,619 patent/US20150093767A1/en not_active Abandoned
-
2016
- 2016-02-19 US US15/048,934 patent/US20170023574A1/en not_active Abandoned
-
2017
- 2017-06-05 US US15/614,513 patent/US20180120319A1/en not_active Abandoned
- 2017-08-11 US US15/675,151 patent/US20180188252A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008529008A5 (enExample) | ||
| JP2008530582A5 (enExample) | ||
| JP2008536098A5 (enExample) | ||
| Jozghorbani et al. | Determination of carcinoembryonic antigen as a tumor marker using a novel graphene-based label-free electrochemical immunosensor | |
| Best et al. | GALAD score detects early hepatocellular carcinoma in an international cohort of patients with nonalcoholic steatohepatitis | |
| Gao et al. | Multiplexed detection of lung cancer biomarkers in patients serum with CMOS-compatible silicon nanowire arrays | |
| Nesterova et al. | Autoantibody biomarker opens a new gateway for cancer diagnosis | |
| Soler et al. | Label-free SPR detection of gluten peptides in urine for non-invasive celiac disease follow-up | |
| Luo et al. | Electrochemical sensor for the simultaneous detection of CA72-4 and CA19-9 tumor markers using dual recognition via glycosyl imprinting and lectin-specific binding for accurate diagnosis of gastric cancer | |
| WO2010038974A3 (ko) | 이뮤노글로블린 에이 신증과 티지비엠 신증의 진단용 조성물 및 키트 | |
| HRP20190533T1 (hr) | Postupak za otkrivanje nukleosoma koji sadrže nukleotide | |
| US20180080937A1 (en) | Biomarker Panel For Diagnosing Cancer | |
| WO2017107974A1 (zh) | 血清psmd4蛋白的检测试剂盒及其检测方法与应用 | |
| Qiao et al. | Serum gp73 is also a biomarker for diagnosing cirrhosis in population with chronic HBV infection | |
| JP2014531573A5 (enExample) | ||
| NO20076656L (no) | Forbedrede immunoassay metoder | |
| JP2011506941A5 (enExample) | ||
| Bertok et al. | Advanced impedimetric biosensor configuration and assay protocol for glycoprofiling of a prostate oncomarker using Au nanoshells with a magnetic core | |
| Wang et al. | MXenes-Au NPs modified electrochemical biosensor for multiple exosome surface proteins analysis | |
| JP2018533724A (ja) | 肝細胞癌および膵臓がんを診断するためのラミニン2の使用 | |
| Ranjan et al. | Scope of biosensors, commercial aspects, and miniaturized devices for point-of-care testing from lab to clinics applications | |
| CN103439511B (zh) | 一种检测肺癌的液相芯片试剂盒 | |
| ES2861440T5 (en) | Use of nucleosome-transcription factor complexes for cancer detection | |
| JP2016519767A5 (enExample) | ||
| CN106680515B (zh) | 用于肺癌诊断的多分子标志物组合 |