ATE490465T1 - Diagnose- und prognoseverfahren von blasenkrebs. - Google Patents
Diagnose- und prognoseverfahren von blasenkrebs.Info
- Publication number
- ATE490465T1 ATE490465T1 AT06719762T AT06719762T ATE490465T1 AT E490465 T1 ATE490465 T1 AT E490465T1 AT 06719762 T AT06719762 T AT 06719762T AT 06719762 T AT06719762 T AT 06719762T AT E490465 T1 ATE490465 T1 AT E490465T1
- Authority
- AT
- Austria
- Prior art keywords
- bladder cancer
- diagnosis
- methods
- present
- epithelial origin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 206010005003 Bladder cancer Diseases 0.000 title abstract 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 201000005112 urinary bladder cancer Diseases 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 102100024341 10 kDa heat shock protein, mitochondrial Human genes 0.000 abstract 1
- 108010059013 Chaperonin 10 Proteins 0.000 abstract 1
- 108010061635 Cystatin B Proteins 0.000 abstract 1
- 102100026891 Cystatin-B Human genes 0.000 abstract 1
- 102000011195 Profilin Human genes 0.000 abstract 1
- 108050001408 Profilin Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64811005P | 2005-01-28 | 2005-01-28 | |
| PCT/US2006/003049 WO2006081473A2 (en) | 2005-01-28 | 2006-01-30 | Methods for diagnosis and prognosis of epithelial cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490465T1 true ATE490465T1 (de) | 2010-12-15 |
Family
ID=36741098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06719762T ATE490465T1 (de) | 2005-01-28 | 2006-01-30 | Diagnose- und prognoseverfahren von blasenkrebs. |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8685659B2 (enExample) |
| EP (1) | EP1842065B1 (enExample) |
| JP (1) | JP2008529008A (enExample) |
| CN (1) | CN101268368A (enExample) |
| AT (1) | ATE490465T1 (enExample) |
| AU (1) | AU2006207954A1 (enExample) |
| CA (1) | CA2595377A1 (enExample) |
| DE (1) | DE602006018578D1 (enExample) |
| WO (1) | WO2006081473A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| EP1512970A1 (en) * | 2003-09-05 | 2005-03-09 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Method for determining the impact of a multicomponent mixture on the biological profile of a disease |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| CA2595377A1 (en) * | 2005-01-28 | 2006-08-03 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| EP2364774A3 (en) | 2006-01-11 | 2014-06-04 | Raindance Technologies, Inc. | Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| EP2021113A2 (en) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| EP2077912B1 (en) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| KR100767878B1 (ko) * | 2006-11-07 | 2007-10-17 | 전북대학교산학협력단 | 간세포암 진단용 조성물, 이를 포함하는 간세포암 진단키트 및 간세포암 진단방법 |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| WO2008103815A2 (en) * | 2007-02-23 | 2008-08-28 | Predictive Biosciences Corporation | Clinical intervention directed diagnostic methods |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| WO2009017475A1 (en) * | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| JP5120843B2 (ja) * | 2008-06-04 | 2013-01-16 | 国立大学法人山梨大学 | 自己免疫性膵炎の検査方法及び検査試薬 |
| EP4047367A1 (en) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Method for detecting target analytes with droplet libraries |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2486409A1 (en) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| WO2011079176A2 (en) | 2009-12-23 | 2011-06-30 | Raindance Technologies, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP3392349A1 (en) | 2010-02-12 | 2018-10-24 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US10436797B2 (en) * | 2010-06-03 | 2019-10-08 | Idexx Laboratories, Inc. | Markers for renal disease |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| US9364803B2 (en) | 2011-02-11 | 2016-06-14 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| EP3736281A1 (en) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Compositions and methods for molecular labeling |
| EP3709018A1 (en) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Microfluidic apparatus for identifying components of a chemical reaction |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| US20130115599A1 (en) * | 2011-11-08 | 2013-05-09 | Medical Diagnostic Laboratories, Llc | Increased cip2a expression and bladder cancer in humans |
| EP3495817B1 (en) | 2012-02-10 | 2024-10-16 | Bio-Rad Laboratories, Inc. | Molecular diagnostic screening assay |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| US10568869B2 (en) * | 2012-12-11 | 2020-02-25 | Cornell University | Methods for diagnosing and treating prostate cancer |
| WO2014172288A2 (en) | 2013-04-19 | 2014-10-23 | Raindance Technologies, Inc. | Digital analyte analysis |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10712349B2 (en) | 2014-04-15 | 2020-07-14 | The Brigham And Women's Hospital, Inc. | Circulating KIM-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| NZ745263A (en) * | 2016-03-02 | 2022-07-01 | Idexx Lab Inc | Methods and compositions for the detection and diagnosis of renal disease and periodontal disease |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| WO2022006514A1 (en) * | 2020-07-02 | 2022-01-06 | Gopath Laboratories Llc | Immune profiling and methods of using same to predict responsiveness to an immunotherapy and treat cancer |
| CN112379093B (zh) * | 2020-10-22 | 2023-06-16 | 上海良润生物医药科技有限公司 | CST-Cathepsin复合物作为肿瘤诊断标志物的应用 |
| CN119604763A (zh) * | 2022-01-26 | 2025-03-11 | 艾德克斯实验室公司 | 用于区分进展性慢性肾脏疾病与稳定性慢性肾脏疾病的方法和组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| NZ267842A (en) | 1993-05-28 | 1997-09-22 | Baylor College Medicine | Apparatus for measuring molecular mass (by mass spectrometry) in which the sample is ionised on the sample holder and desorbed therefrom by laser pulses |
| US5702892A (en) | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| JP2001524802A (ja) | 1996-07-15 | 2001-12-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 20q13アンプリコンからの遺伝子及びそれらの使用 |
| JPH10262680A (ja) * | 1997-03-25 | 1998-10-06 | Kirin Brewery Co Ltd | Rho標的タンパク質ヒトmDiaおよびその遺伝子 |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6642007B1 (en) | 1998-11-02 | 2003-11-04 | Pfizer Inc. | Assays for measurement of type II collagen fragments in urine |
| US20030124543A1 (en) | 1999-01-15 | 2003-07-03 | Stuart Susan G. | Breast cancer marker |
| US6358683B1 (en) | 1999-06-03 | 2002-03-19 | The Regents Of The University Of California | Blood-based assays for breast cancer |
| US6939714B2 (en) * | 1999-06-18 | 2005-09-06 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
| WO2001018058A2 (en) | 1999-09-07 | 2001-03-15 | Viventia Biotech Inc. | Enhanced phage display library of human vh fragments and methods for producing same |
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| KR20030031911A (ko) | 2001-04-19 | 2003-04-23 | 싸이퍼젠 바이오시스템즈, 인코포레이티드 | 질량 분석법과 친화성 태그를 이용한 생물분자 특성화 |
| US7112408B2 (en) | 2001-06-08 | 2006-09-26 | The Brigham And Women's Hospital, Inc. | Detection of ovarian cancer based upon alpha-haptoglobin levels |
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| US20040009212A1 (en) | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| US20030157579A1 (en) * | 2002-02-14 | 2003-08-21 | Kalobios, Inc. | Molecular sensors activated by disinhibition |
| US20030199001A1 (en) | 2002-04-23 | 2003-10-23 | Pitt Aldo M. | Sample preparation of biological fluids for proteomic applications |
| US7191068B2 (en) | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
| US20070178090A1 (en) | 2003-04-01 | 2007-08-02 | Genzyme Corporation | Breast endothelial cell expression patterns |
| CA2595377A1 (en) * | 2005-01-28 | 2006-08-03 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| WO2009017475A1 (en) | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
-
2006
- 2006-01-30 CA CA002595377A patent/CA2595377A1/en not_active Abandoned
- 2006-01-30 AU AU2006207954A patent/AU2006207954A1/en not_active Abandoned
- 2006-01-30 US US11/814,939 patent/US8685659B2/en not_active Expired - Fee Related
- 2006-01-30 CN CNA2006800098728A patent/CN101268368A/zh active Pending
- 2006-01-30 WO PCT/US2006/003049 patent/WO2006081473A2/en not_active Ceased
- 2006-01-30 AT AT06719762T patent/ATE490465T1/de not_active IP Right Cessation
- 2006-01-30 JP JP2007553289A patent/JP2008529008A/ja active Pending
- 2006-01-30 EP EP06719762A patent/EP1842065B1/en not_active Not-in-force
- 2006-01-30 DE DE602006018578T patent/DE602006018578D1/de active Active
-
2007
- 2007-07-27 US US11/829,323 patent/US20080064047A1/en not_active Abandoned
-
2013
- 2013-04-17 US US13/864,707 patent/US20140106378A1/en not_active Abandoned
-
2014
- 2014-10-01 US US14/503,619 patent/US20150093767A1/en not_active Abandoned
-
2016
- 2016-02-19 US US15/048,934 patent/US20170023574A1/en not_active Abandoned
-
2017
- 2017-06-05 US US15/614,513 patent/US20180120319A1/en not_active Abandoned
- 2017-08-11 US US15/675,151 patent/US20180188252A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1842065B1 (en) | 2010-12-01 |
| US20170023574A1 (en) | 2017-01-26 |
| AU2006207954A1 (en) | 2006-08-03 |
| CN101268368A (zh) | 2008-09-17 |
| US20180188252A1 (en) | 2018-07-05 |
| WO2006081473A8 (en) | 2007-08-23 |
| EP1842065A2 (en) | 2007-10-10 |
| JP2008529008A (ja) | 2008-07-31 |
| DE602006018578D1 (de) | 2011-01-13 |
| EP1842065A4 (en) | 2008-12-31 |
| WO2006081473A3 (en) | 2007-01-18 |
| US20080064047A1 (en) | 2008-03-13 |
| US20180120319A1 (en) | 2018-05-03 |
| US8685659B2 (en) | 2014-04-01 |
| US20090239245A1 (en) | 2009-09-24 |
| WO2006081473A2 (en) | 2006-08-03 |
| US20140106378A1 (en) | 2014-04-17 |
| CA2595377A1 (en) | 2006-08-03 |
| US20150093767A1 (en) | 2015-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |