CA2595377A1 - Methods for diagnosis and prognosis of epithelial cancers - Google Patents

Methods for diagnosis and prognosis of epithelial cancers Download PDF

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Publication number
CA2595377A1
CA2595377A1 CA002595377A CA2595377A CA2595377A1 CA 2595377 A1 CA2595377 A1 CA 2595377A1 CA 002595377 A CA002595377 A CA 002595377A CA 2595377 A CA2595377 A CA 2595377A CA 2595377 A1 CA2595377 A1 CA 2595377A1
Authority
CA
Canada
Prior art keywords
cancer
cystatin
epithelial
antibody
biomarker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002595377A
Other languages
English (en)
French (fr)
Inventor
Bruce R. Zetter
Adam S. Feldman
W. Scott Mcdougal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Boston Children's Hospital
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2595377A1 publication Critical patent/CA2595377A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002595377A 2005-01-28 2006-01-30 Methods for diagnosis and prognosis of epithelial cancers Abandoned CA2595377A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64811005P 2005-01-28 2005-01-28
US60/648,110 2005-01-28
PCT/US2006/003049 WO2006081473A2 (en) 2005-01-28 2006-01-30 Methods for diagnosis and prognosis of epithelial cancers

Publications (1)

Publication Number Publication Date
CA2595377A1 true CA2595377A1 (en) 2006-08-03

Family

ID=36741098

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002595377A Abandoned CA2595377A1 (en) 2005-01-28 2006-01-30 Methods for diagnosis and prognosis of epithelial cancers

Country Status (9)

Country Link
US (7) US8685659B2 (enExample)
EP (1) EP1842065B1 (enExample)
JP (1) JP2008529008A (enExample)
CN (1) CN101268368A (enExample)
AT (1) ATE490465T1 (enExample)
AU (1) AU2006207954A1 (enExample)
CA (1) CA2595377A1 (enExample)
DE (1) DE602006018578D1 (enExample)
WO (1) WO2006081473A2 (enExample)

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US10712349B2 (en) 2014-04-15 2020-07-14 The Brigham And Women's Hospital, Inc. Circulating KIM-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney
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Also Published As

Publication number Publication date
CN101268368A (zh) 2008-09-17
WO2006081473A2 (en) 2006-08-03
WO2006081473A3 (en) 2007-01-18
US20180188252A1 (en) 2018-07-05
DE602006018578D1 (de) 2011-01-13
JP2008529008A (ja) 2008-07-31
US20180120319A1 (en) 2018-05-03
US8685659B2 (en) 2014-04-01
US20140106378A1 (en) 2014-04-17
EP1842065A2 (en) 2007-10-10
AU2006207954A1 (en) 2006-08-03
US20090239245A1 (en) 2009-09-24
US20170023574A1 (en) 2017-01-26
US20080064047A1 (en) 2008-03-13
US20150093767A1 (en) 2015-04-02
ATE490465T1 (de) 2010-12-15
EP1842065A4 (en) 2008-12-31
EP1842065B1 (en) 2010-12-01
WO2006081473A8 (en) 2007-08-23

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20170419