ATE490465T1 - Diagnose- und prognoseverfahren von blasenkrebs. - Google Patents
Diagnose- und prognoseverfahren von blasenkrebs.Info
- Publication number
- ATE490465T1 ATE490465T1 AT06719762T AT06719762T ATE490465T1 AT E490465 T1 ATE490465 T1 AT E490465T1 AT 06719762 T AT06719762 T AT 06719762T AT 06719762 T AT06719762 T AT 06719762T AT E490465 T1 ATE490465 T1 AT E490465T1
- Authority
- AT
- Austria
- Prior art keywords
- bladder cancer
- diagnosis
- methods
- present
- epithelial origin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 206010005003 Bladder cancer Diseases 0.000 title abstract 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 201000005112 urinary bladder cancer Diseases 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 102100024341 10 kDa heat shock protein, mitochondrial Human genes 0.000 abstract 1
- 108010059013 Chaperonin 10 Proteins 0.000 abstract 1
- 108010061635 Cystatin B Proteins 0.000 abstract 1
- 102100026891 Cystatin-B Human genes 0.000 abstract 1
- 102000011195 Profilin Human genes 0.000 abstract 1
- 108050001408 Profilin Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64811005P | 2005-01-28 | 2005-01-28 | |
| PCT/US2006/003049 WO2006081473A2 (en) | 2005-01-28 | 2006-01-30 | Methods for diagnosis and prognosis of epithelial cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490465T1 true ATE490465T1 (de) | 2010-12-15 |
Family
ID=36741098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06719762T ATE490465T1 (de) | 2005-01-28 | 2006-01-30 | Diagnose- und prognoseverfahren von blasenkrebs. |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8685659B2 (de) |
| EP (1) | EP1842065B1 (de) |
| JP (1) | JP2008529008A (de) |
| CN (1) | CN101268368A (de) |
| AT (1) | ATE490465T1 (de) |
| AU (1) | AU2006207954A1 (de) |
| CA (1) | CA2595377A1 (de) |
| DE (1) | DE602006018578D1 (de) |
| WO (1) | WO2006081473A2 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| EP1512970A1 (de) * | 2003-09-05 | 2005-03-09 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Verfahren zur Bestimmung der Wirkung einer Zusammensetzung auf das Profil einer Krankheit |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| AU2006207954A1 (en) * | 2005-01-28 | 2006-08-03 | Childrens Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| EP1984738A2 (de) | 2006-01-11 | 2008-10-29 | Raindance Technologies, Inc. | Mikrofluidische vorrichtungen und verfahren zur verwendung bei der bildung und kontrolle von nanoreaktoren |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| WO2007133710A2 (en) | 2006-05-11 | 2007-11-22 | Raindance Technologies, Inc. | Microfluidic devices and methods of use thereof |
| EP2077912B1 (de) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorkohlenstoffemulsionsstabilisierende tenside |
| KR100767878B1 (ko) * | 2006-11-07 | 2007-10-17 | 전북대학교산학협력단 | 간세포암 진단용 조성물, 이를 포함하는 간세포암 진단키트 및 간세포암 진단방법 |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| CA2679205A1 (en) * | 2007-02-23 | 2008-08-28 | Predictive Biosciences Corporation | Clinical intervention directed diagnostic methods |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| WO2009017475A1 (en) * | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| JP5120843B2 (ja) * | 2008-06-04 | 2013-01-16 | 国立大学法人山梨大学 | 自己免疫性膵炎の検査方法及び検査試薬 |
| WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US8528589B2 (en) | 2009-03-23 | 2013-09-10 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2486409A1 (de) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Markiertes nanomaterial auf siliziumbasis mit verbesserten eigenschaften und seine verwendung |
| WO2011079176A2 (en) | 2009-12-23 | 2011-06-30 | Raindance Technologies, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| EP4484577A3 (de) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digitale analytanalyse |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| WO2011153469A1 (en) | 2010-06-03 | 2011-12-08 | Idexx Laboratories, Inc. | Markers for renal disease |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| EP3709018A1 (de) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Mikrofluidische vorrichtung zum nachweis von komponenten einer chemischen reaktion |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| US20130115599A1 (en) * | 2011-11-08 | 2013-05-09 | Medical Diagnostic Laboratories, Llc | Increased cip2a expression and bladder cancer in humans |
| EP3495817B1 (de) | 2012-02-10 | 2024-10-16 | Bio-Rad Laboratories, Inc. | Molekulardiagnostischer screeningtest |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| AU2013359398B2 (en) * | 2012-12-11 | 2019-08-15 | Cornell University | Methods for diagnosing and treating prostate cancer |
| WO2014172288A2 (en) | 2013-04-19 | 2014-10-23 | Raindance Technologies, Inc. | Digital analyte analysis |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10712349B2 (en) | 2014-04-15 | 2020-07-14 | The Brigham And Women's Hospital, Inc. | Circulating KIM-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| DK3423838T5 (da) * | 2016-03-02 | 2024-09-16 | Idexx Lab Inc | Fremgangsmåde og sammensætninger til påvisning og diagnosticering af nyresygdom og peridontal sygdom |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| WO2022006514A1 (en) * | 2020-07-02 | 2022-01-06 | Gopath Laboratories Llc | Immune profiling and methods of using same to predict responsiveness to an immunotherapy and treat cancer |
| CN112379093B (zh) * | 2020-10-22 | 2023-06-16 | 上海良润生物医药科技有限公司 | CST-Cathepsin复合物作为肿瘤诊断标志物的应用 |
| CA3248223A1 (en) * | 2022-01-26 | 2023-08-03 | Idexx Laboratories, Inc. | METHODS AND COMPOSITIONS FOR DIFFERENTIATING PROGRESSIVE CHRONIC KIDNEY DISEASE FROM STABLE CHRONIC KIDNEY DISEASE |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| DE69432791T2 (de) | 1993-05-28 | 2004-06-03 | Baylor College Of Medicine, Houston | Verfahren und massenspektrometer zur desorption und ionisierung von analyten |
| US5702892A (en) | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| US6808878B1 (en) | 1996-07-15 | 2004-10-26 | The Regents Of The University Of California | Genes from the 20Q13 amplicon and their uses |
| JPH10262680A (ja) | 1997-03-25 | 1998-10-06 | Kirin Brewery Co Ltd | Rho標的タンパク質ヒトmDiaおよびその遺伝子 |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6642007B1 (en) | 1998-11-02 | 2003-11-04 | Pfizer Inc. | Assays for measurement of type II collagen fragments in urine |
| US20030124543A1 (en) | 1999-01-15 | 2003-07-03 | Stuart Susan G. | Breast cancer marker |
| US6358683B1 (en) | 1999-06-03 | 2002-03-19 | The Regents Of The University Of California | Blood-based assays for breast cancer |
| US6939714B2 (en) * | 1999-06-18 | 2005-09-06 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
| WO2001018058A2 (en) | 1999-09-07 | 2001-03-15 | Viventia Biotech Inc. | Enhanced phage display library of human vh fragments and methods for producing same |
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| US7429466B2 (en) | 2000-01-24 | 2008-09-30 | Hypromatrix, Inc | Methods and arrays for detecting biological molecules |
| US20030077616A1 (en) | 2001-04-19 | 2003-04-24 | Ciphergen Biosystems, Inc. | Biomolecule characterization using mass spectrometry and affinity tags |
| US7112408B2 (en) | 2001-06-08 | 2006-09-26 | The Brigham And Women's Hospital, Inc. | Detection of ovarian cancer based upon alpha-haptoglobin levels |
| US20040076955A1 (en) | 2001-07-03 | 2004-04-22 | Eos Biotechnology, Inc. | Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer |
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| IL160324A0 (en) | 2001-08-13 | 2004-07-25 | Beyond Genomics Inc | Method and system for profiling biological systems |
| US20040009212A1 (en) * | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| US20030157579A1 (en) * | 2002-02-14 | 2003-08-21 | Kalobios, Inc. | Molecular sensors activated by disinhibition |
| EP1497663A1 (de) | 2002-04-23 | 2005-01-19 | Millipore Corporation | Probenvorbereitung von biologischen flüssigkeiten für proteomische anwendungen |
| US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
| JP2007525167A (ja) | 2003-04-01 | 2007-09-06 | ジェンザイム・コーポレーション | 乳房内皮細胞発現パターン |
| AU2006207954A1 (en) * | 2005-01-28 | 2006-08-03 | Childrens Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
| WO2009017475A1 (en) | 2007-07-27 | 2009-02-05 | Children's Medical Center Corporation | Methods for diagnosis and prognosis of epithelial cancers |
-
2006
- 2006-01-30 AU AU2006207954A patent/AU2006207954A1/en not_active Abandoned
- 2006-01-30 DE DE602006018578T patent/DE602006018578D1/de active Active
- 2006-01-30 JP JP2007553289A patent/JP2008529008A/ja active Pending
- 2006-01-30 US US11/814,939 patent/US8685659B2/en not_active Expired - Fee Related
- 2006-01-30 CA CA002595377A patent/CA2595377A1/en not_active Abandoned
- 2006-01-30 EP EP06719762A patent/EP1842065B1/de not_active Not-in-force
- 2006-01-30 CN CNA2006800098728A patent/CN101268368A/zh active Pending
- 2006-01-30 WO PCT/US2006/003049 patent/WO2006081473A2/en not_active Ceased
- 2006-01-30 AT AT06719762T patent/ATE490465T1/de not_active IP Right Cessation
-
2007
- 2007-07-27 US US11/829,323 patent/US20080064047A1/en not_active Abandoned
-
2013
- 2013-04-17 US US13/864,707 patent/US20140106378A1/en not_active Abandoned
-
2014
- 2014-10-01 US US14/503,619 patent/US20150093767A1/en not_active Abandoned
-
2016
- 2016-02-19 US US15/048,934 patent/US20170023574A1/en not_active Abandoned
-
2017
- 2017-06-05 US US15/614,513 patent/US20180120319A1/en not_active Abandoned
- 2017-08-11 US US15/675,151 patent/US20180188252A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2595377A1 (en) | 2006-08-03 |
| WO2006081473A8 (en) | 2007-08-23 |
| US20140106378A1 (en) | 2014-04-17 |
| DE602006018578D1 (de) | 2011-01-13 |
| US20090239245A1 (en) | 2009-09-24 |
| US20180188252A1 (en) | 2018-07-05 |
| US20150093767A1 (en) | 2015-04-02 |
| AU2006207954A1 (en) | 2006-08-03 |
| JP2008529008A (ja) | 2008-07-31 |
| US20080064047A1 (en) | 2008-03-13 |
| WO2006081473A3 (en) | 2007-01-18 |
| EP1842065B1 (de) | 2010-12-01 |
| US20170023574A1 (en) | 2017-01-26 |
| US8685659B2 (en) | 2014-04-01 |
| WO2006081473A2 (en) | 2006-08-03 |
| US20180120319A1 (en) | 2018-05-03 |
| EP1842065A4 (de) | 2008-12-31 |
| EP1842065A2 (de) | 2007-10-10 |
| CN101268368A (zh) | 2008-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |