JP2008529669A - 光学コヒーレンス断層撮影法の装置及び方法 - Google Patents
光学コヒーレンス断層撮影法の装置及び方法 Download PDFInfo
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
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- G01N21/8507—Probe photometers, i.e. with optical measuring part dipped into fluid sample
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- G—PHYSICS
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- G—PHYSICS
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- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/70—Using polarization in the interferometer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N2021/178—Methods for obtaining spatial resolution of the property being measured
- G01N2021/1785—Three dimensional
- G01N2021/1787—Tomographic, i.e. computerised reconstruction from projective measurements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
- G01N21/8507—Probe photometers, i.e. with optical measuring part dipped into fluid sample
- G01N2021/8514—Probe photometers, i.e. with optical measuring part dipped into fluid sample with immersed mirror
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
- G01N21/8507—Probe photometers, i.e. with optical measuring part dipped into fluid sample
- G01N2021/8528—Immerged light conductor
Abstract
Description
Claims (21)
- 撮影プローブであって、
近位端と遠位端とを有した細長体を備え、当該細長体はスライド可能な光ファイバの一部を取り囲むように構成され、当該光ファイバは長手方向軸を有しており、
当該ファイバの遠位端に取り付けられた第1の光学アセンブリをさらに備え、当該第1の光学アセンブリは前記ファイバから放射された光を、前記長手方向軸に対して所定角度に設定された面に向けるように構成されたビーム偏向器を有しており、
前記細長体の近位部に配置されたリニアアクチュエータをさらに備え、当該アクチュエータは前記細長体と前記光ファイバとの間の相対的なリニア運動を生じさせるように構成されており、
前記細長体の遠位部に配置されているとともにそこに取り付けられた第2の光学アセンブリをさらに備え、当該第2の光学アセンブリは前記第1の光学アセンブリと光学的に連通した反射器を有しており、当該反射器は前記細長体よりも遠位側へ光を向けるように構成されていることを特徴とする撮影プローブ。 - 前記反射器の位置は、前記相対的なリニア運動に対応して前記光が前方視方向において走査を行うように設定されていることを特徴とする請求項1に記載の撮影プローブ。
- 前記細長体を概ね取り囲む固定コアをさらに備えており、当該固定コアは当該固定コアの回転に対応してカテーテル先端の撮影位置が変化するように構成されていることを特徴とする請求項1に記載の撮影プローブ。
- 前記第1の光学アセンブリはさらに、前記光ファイバ先端に配置された集束マイクロレンズと、前記細長体内に設置され、走査ビームの前方視野角及び距離を大幅に適正化する角度に傾斜された単一の反射器と、を備えており、
これらレンズ及び反射器は、前記細長体の前記遠位端よりも遠位側に配置され、かつ前記ファイバの前記長手方向軸に対して概ね直交とされた撮影面を形成することを特徴とする請求項1に記載の撮影プローブ。 - 前記反射器と光学的窓は、前記細長体に取り付けられた透明の光学材料のブロックにより構成されていることを特徴とする請求項1に記載の撮影プローブ。
- 前記第1の光学アセンブリは、斜め研磨加工が施された先端を有する光ファイバを備えており、前記第2の光学アセンブリは、前記細長体の外側に取り付けられたハウジング内に対のマイクロレンズを有する前記反射器を備えていることを特徴とする請求項1に記載の撮影プローブ。
- 前記レンズの焦点距離及び位置は、所望の焦点サイズ及び作動距離を実現するように選択されていることを特徴とする請求項6に記載の撮影プローブ。
- 前記光学アセンブリは、斜め研磨加工が施された先端を有する光ファイバと、前記細長体に外側に取り付けられたハウジング内に単一の屈折率分布型レンズを有する反射器とを備えており、
前記屈折率分布型レンズの屈折率プロファイル及び位置は、所望の焦点サイズ及び作動距離を実現するように選択されていることを特徴とする請求項1に記載の撮影プローブ。 - 前記リニアアクチュエータはボイスコイルを備えていることを特徴とする請求項1に記載の撮影プローブ。
- 前記リニアアクチュエータは、前記ファイバを当該アクチュエータに対して固定状態としながら前記シースを移動させるように構成されていることを特徴とする請求項1に記載の撮影プローブ。
- 前記細長体は流体で満たされているとともに、前記光ファイバの周りで前後に移動するように構成されていることを特徴とする請求項1に記載の撮影プローブ。
- 光が放射される先端を除き前記光ファイバを概ね覆う金属チューブと、当該金属チューブ及び前記光ファイバに対して移動するように構成され、流体で満たされた外側シースと、をさらに備えていることを特徴とする請求項1に記載の撮影プローブ。
- 生物組織走査の関連用途のために、光学コヒーレンス断層撮影法システムのサンプルアーム系で用いられるように構成されていることを特徴とする請求項1に記載の撮影プローブ。
- 光学コヒーレンス断層撮影法システムにおけるリファレンスアーム系又はサンプルアーム系のいずれか一方には光路長調整手段が含まれており、当該手段はアクチュエータ走査により誘発される光路長の変化を自動的に補正するものであることを特徴とする請求項12に記載の撮影プローブ。
- 前記ビームは、前記アクチュエータのリニア運動に同期して線状に走査するものであることを特徴とする請求項1に記載の撮影プローブ。
- 前記細長体は、湾曲した先端をさらに備えており、少なくとも当該先端の一部は前記リニア運動に応じて光を放射するように構成されていることを特徴とする請求項1に記載の撮影プローブ。
- リニアアクチュエータと、
当該リニアアクチュエータに機械的に接続され、傾斜端面を有するシングルモード光ファイバと、
前記反射器に対する前記光ファイバ端面の動作により、前記光ファイバ端面からの光が光ファイバの円形横断面に対し概ね平行な面に向けられる角度に設置された反射器を有するシースと、
を備えていることを特徴とする光学コヒーレンス断層撮影法の前方走査システム。 - 光ファイバの回転ひずみ緩和装置をさらに備えており、当該装置は前記ファイバと機械的に接続されていることを特徴とする請求項17に記載のシステム。
- 回転ひずみ緩和装置であって、
第1のポートと第2のポートとを有するチューブを備えており、当該チューブは少なくとも一のループ部を形成するように構成されており、
前記第1のポートは光学コヒーレンス断層撮影法の撮影プローブと接続するように構成されており、前記チューブ内部は光ファイバのスライドを容易なものとするように構成されていることを特徴とする光ファイバの回転ひずみ緩和装置。 - 前記第2のポートは干渉計のサンプルアーム系と接続するように構成されていることを特徴とする請求項19に記載の装置。
- 前記ループ部は概ね円形であることを特徴とする請求項19に記載の装置。
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US65183105P | 2005-02-10 | 2005-02-10 | |
PCT/US2006/004863 WO2006086700A2 (en) | 2005-02-10 | 2006-02-10 | Optical coherence tomography apparatus and methods |
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US7848791B2 (en) | 2010-12-07 |
WO2006086700A2 (en) | 2006-08-17 |
EP1850735A2 (en) | 2007-11-07 |
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