JP2008525468A - ポストコンディショニング臓器保護作用を増強する治療補助薬 - Google Patents

ポストコンディショニング臓器保護作用を増強する治療補助薬 Download PDF

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JP2008525468A
JP2008525468A JP2007548436A JP2007548436A JP2008525468A JP 2008525468 A JP2008525468 A JP 2008525468A JP 2007548436 A JP2007548436 A JP 2007548436A JP 2007548436 A JP2007548436 A JP 2007548436A JP 2008525468 A JP2008525468 A JP 2008525468A
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tissue
inhibitor
organ
perfusion
reperfusion
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JP2008525468A5 (https=
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ジェイコブ−ビンテン・ジョハンセン
チ−キン・チャオ
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エモリー・ユニバーシティ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
JP2007548436A 2004-12-22 2005-12-20 ポストコンディショニング臓器保護作用を増強する治療補助薬 Withdrawn JP2008525468A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63846104P 2004-12-22 2004-12-22
PCT/US2005/046417 WO2006069170A2 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Publications (2)

Publication Number Publication Date
JP2008525468A true JP2008525468A (ja) 2008-07-17
JP2008525468A5 JP2008525468A5 (https=) 2009-01-29

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JP2007548436A Withdrawn JP2008525468A (ja) 2004-12-22 2005-12-20 ポストコンディショニング臓器保護作用を増強する治療補助薬

Country Status (6)

Country Link
US (1) US20080097385A1 (https=)
EP (1) EP1827298A4 (https=)
JP (1) JP2008525468A (https=)
AU (1) AU2005319144A1 (https=)
CA (1) CA2592142A1 (https=)
WO (1) WO2006069170A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012210361A (ja) * 2011-03-31 2012-11-01 Terumo Corp 肢部圧迫装置
JP2013510832A (ja) * 2009-11-16 2013-03-28 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック A型インフルエンザウイルス感染症の治療または予防用のpar−1アンタゴニスト
JP2013523240A (ja) * 2010-03-31 2013-06-17 ザ・ホスピタル・フォー・シック・チルドレン 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用

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JP2015500733A (ja) 2011-12-19 2015-01-08 レスキューシステムズ インコーポレイテッドResqsystems,Inc. 治療のための胸腔内圧調節システムおよび方法
JP2016512709A (ja) 2013-03-15 2016-05-09 ザ・ホスピタル・フォー・シック・チルドレンThe Hospital For Sick Children 遠隔虚血コンディショニングを用いてオートファジをモジュレートする方法
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510832A (ja) * 2009-11-16 2013-03-28 アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミック A型インフルエンザウイルス感染症の治療または予防用のpar−1アンタゴニスト
JP2013523240A (ja) * 2010-03-31 2013-06-17 ザ・ホスピタル・フォー・シック・チルドレン 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用
JP2016052600A (ja) * 2010-03-31 2016-04-14 ザ・ホスピタル・フォー・シック・チルドレンThe Hospital For Sick Children 心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用
JP2012210361A (ja) * 2011-03-31 2012-11-01 Terumo Corp 肢部圧迫装置

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EP1827298A2 (en) 2007-09-05
WO2006069170A3 (en) 2007-01-04
AU2005319144A1 (en) 2006-06-29
CA2592142A1 (en) 2006-06-29
US20080097385A1 (en) 2008-04-24
WO2006069170A2 (en) 2006-06-29
EP1827298A4 (en) 2011-09-28

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