AU2005319144A1 - Therapeutic adjuncts to enhance the organ protective effects of postconditioning - Google Patents

Therapeutic adjuncts to enhance the organ protective effects of postconditioning Download PDF

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Publication number
AU2005319144A1
AU2005319144A1 AU2005319144A AU2005319144A AU2005319144A1 AU 2005319144 A1 AU2005319144 A1 AU 2005319144A1 AU 2005319144 A AU2005319144 A AU 2005319144A AU 2005319144 A AU2005319144 A AU 2005319144A AU 2005319144 A1 AU2005319144 A1 AU 2005319144A1
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AU
Australia
Prior art keywords
tissue
organ
inhibitors
heart
perfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2005319144A
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English (en)
Inventor
Jakob-Vinten Johansen
Zhi-Qing Zhao
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Emory University
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Emory University
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Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Publication of AU2005319144A1 publication Critical patent/AU2005319144A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
AU2005319144A 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning Abandoned AU2005319144A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63846104P 2004-12-22 2004-12-22
US60/638,461 2004-12-22
PCT/US2005/046417 WO2006069170A2 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Publications (1)

Publication Number Publication Date
AU2005319144A1 true AU2005319144A1 (en) 2006-06-29

Family

ID=36602296

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005319144A Abandoned AU2005319144A1 (en) 2004-12-22 2005-12-20 Therapeutic adjuncts to enhance the organ protective effects of postconditioning

Country Status (6)

Country Link
US (1) US20080097385A1 (https=)
EP (1) EP1827298A4 (https=)
JP (1) JP2008525468A (https=)
AU (1) AU2005319144A1 (https=)
CA (1) CA2592142A1 (https=)
WO (1) WO2006069170A2 (https=)

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JP2016512709A (ja) 2013-03-15 2016-05-09 ザ・ホスピタル・フォー・シック・チルドレンThe Hospital For Sick Children 遠隔虚血コンディショニングを用いてオートファジをモジュレートする方法
WO2014199239A2 (en) 2013-03-15 2014-12-18 The Hospital For Sick Children Methods relating to the use of remote ischemic conditioning
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Also Published As

Publication number Publication date
EP1827298A2 (en) 2007-09-05
WO2006069170A3 (en) 2007-01-04
CA2592142A1 (en) 2006-06-29
US20080097385A1 (en) 2008-04-24
JP2008525468A (ja) 2008-07-17
WO2006069170A2 (en) 2006-06-29
EP1827298A4 (en) 2011-09-28

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Legal Events

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application