JP2008521538A5 - - Google Patents
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- Publication number
- JP2008521538A5 JP2008521538A5 JP2007544006A JP2007544006A JP2008521538A5 JP 2008521538 A5 JP2008521538 A5 JP 2008521538A5 JP 2007544006 A JP2007544006 A JP 2007544006A JP 2007544006 A JP2007544006 A JP 2007544006A JP 2008521538 A5 JP2008521538 A5 JP 2008521538A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- oxygen
- chamber
- functional
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 23
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 20
- 229910052760 oxygen Inorganic materials 0.000 claims 20
- 239000001301 oxygen Substances 0.000 claims 20
- 239000000126 substance Substances 0.000 claims 5
- 239000000499 gel Substances 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 2
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 2
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 2
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 239000000017 hydrogel Substances 0.000 claims 2
- 230000002611 ovarian Effects 0.000 claims 2
- 239000011850 water-based material Substances 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 229920000936 Agarose Polymers 0.000 claims 1
- 210000002237 B-cell of pancreatic islet Anatomy 0.000 claims 1
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 230000001919 adrenal effect Effects 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 230000001054 cortical effect Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 238000005868 electrolysis reaction Methods 0.000 claims 1
- 210000005229 liver cell Anatomy 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 230000000849 parathyroid Effects 0.000 claims 1
- -1 perfluorocarbon compound Chemical class 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 210000001550 testis Anatomy 0.000 claims 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 1
- 210000001685 thyroid gland Anatomy 0.000 claims 1
- 210000003556 vascular endothelial cell Anatomy 0.000 claims 1
- 230000006444 vascular growth Effects 0.000 claims 1
- 230000008728 vascular permeability Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/001,556 US8012500B2 (en) | 2000-01-01 | 2004-11-30 | Implantable device |
| PCT/IL2005/001262 WO2006059322A2 (en) | 2004-11-30 | 2005-11-27 | Implantable device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008521538A JP2008521538A (ja) | 2008-06-26 |
| JP2008521538A5 true JP2008521538A5 (https=) | 2009-09-03 |
Family
ID=36565437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007544006A Pending JP2008521538A (ja) | 2004-11-30 | 2005-11-27 | 移植可能な器具 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8012500B2 (https=) |
| EP (1) | EP1827490A4 (https=) |
| JP (1) | JP2008521538A (https=) |
| CN (1) | CN101123984B (https=) |
| WO (1) | WO2006059322A2 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL134009A (en) * | 2000-01-12 | 2011-07-31 | Bo2 Technologies Ltd | Transplant device |
| US8012500B2 (en) * | 2000-01-01 | 2011-09-06 | Beta-O2 Technologies Ltd. | Implantable device |
| WO2008062417A2 (en) * | 2006-11-22 | 2008-05-29 | Beta O2 Technologies Ltd. | Protecting algae from body fluids |
| ES2659988T3 (es) | 2006-11-28 | 2018-03-20 | Beta O2 Technologies Ltd. | Suministro de oxígeno para el transplante celular y la vascularización |
| WO2008079997A2 (en) * | 2006-12-22 | 2008-07-03 | Medtronic, Inc. | Implantable device, angiogenesis mechanism and methods |
| US8821431B2 (en) * | 2007-09-07 | 2014-09-02 | Beta O2 Technologies Ltd. | Air gap for supporting cells |
| US8369942B2 (en) * | 2008-03-20 | 2013-02-05 | The Invention Science Fund I, Llc | Subdermal material delivery device |
| US20090259171A1 (en) * | 2008-04-09 | 2009-10-15 | Joshi Ashok V | Transdermal Oxygen-Delivery Apparatus and Method |
| US9540630B2 (en) * | 2008-09-17 | 2017-01-10 | Beta O2 Technologies Ltd. | Optimization of alginate encapsulation of islets for transplantation |
| US9446168B2 (en) | 2010-06-07 | 2016-09-20 | Beta-O2 Technologies Ltd. | Multiple-layer immune barrier for donor cells |
| US8043271B2 (en) * | 2008-11-26 | 2011-10-25 | Beta 02 Technologies Ltd. | Apparatus for transportation of oxygen to implanted cells |
| US9357764B2 (en) | 2009-06-18 | 2016-06-07 | Giner, Inc. | System for fluid perfusion of biological matter comprising tissue |
| US10091985B2 (en) * | 2009-06-18 | 2018-10-09 | Giner, Inc. | Perfusing an organ with an in situ generated gas |
| US8784389B2 (en) * | 2009-08-31 | 2014-07-22 | Beta-O2 Technologies Ltd. | Oxygen supply for implantable medical device |
| JP2011083434A (ja) * | 2009-10-15 | 2011-04-28 | Otsuka Pharmaceut Factory Inc | ガス交換装置 |
| EP2389958A1 (en) | 2010-03-22 | 2011-11-30 | Technische Universität Klinikum Rechts der Isar | Use of photosynthetic scaffolds in tissue engineering |
| JP2012031070A (ja) * | 2010-07-28 | 2012-02-16 | Otsuka Pharmaceut Factory Inc | 組織の保存方法、及び組織保存装置 |
| US9146230B2 (en) * | 2011-06-20 | 2015-09-29 | Yoram Palti | Continuous monitoring of glucose and other living body constituents |
| US9919140B2 (en) | 2012-10-05 | 2018-03-20 | University Of Southern California | Implantable oxygenator with self-contained electrolyte |
| CN105792775B (zh) | 2013-09-24 | 2019-02-19 | 吉纳生命科学公司 | 用于细胞植入物的气体处理的系统 |
| US9950151B2 (en) | 2014-03-27 | 2018-04-24 | Beta-O2 Technologies Ltd. | Implantable medical devices |
| EP3188796B1 (en) | 2014-09-03 | 2021-12-22 | Symbiox, Inc. | Photosynthetic cellular substances |
| WO2016059635A1 (en) | 2014-10-13 | 2016-04-21 | Glusense Ltd. | Analyte-sensing device |
| US10137158B2 (en) * | 2015-04-24 | 2018-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Use of photosynthesis to rebalance ischemia bioenergetics |
| WO2016208747A1 (ja) * | 2015-06-25 | 2016-12-29 | 学校法人東京女子医科大学 | 動物細胞組成物の培養方法、それを用いた動物細胞組成物の製造方法、及び動物細胞組成物 |
| EP3445872A1 (en) | 2016-04-20 | 2019-02-27 | Glusense Ltd. | Fret-based glucose-detection molecules |
| US20190241853A1 (en) | 2016-07-12 | 2019-08-08 | Micro Green Technologies Ltd. | Compositions comprising microalgae and methods of producing and using same |
| KR102649881B1 (ko) | 2016-11-03 | 2024-03-20 | 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 | 캡슐화 장치에서 이식 전과 이식 후 세포를 실시간 평가하기 위한 방법 및 시스템 |
| KR20190106996A (ko) * | 2016-11-03 | 2019-09-18 | 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 | 외부 산소 전달을 수반 또는 비-수반하는 산소 센서가 구비된 캡슐화 장치 시스템 |
| KR102460406B1 (ko) * | 2016-11-03 | 2022-10-31 | 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 | 산소 전달을 수반 또는 비-수반하는 적층형 조직 캡슐화 장치 시스템 |
| MX2019005676A (es) | 2016-11-15 | 2019-09-10 | Giner Life Sciences Inc | Dispositivo percutáneo de difusión de gases adecuado para su uso con un implante subcutáneo. |
| JP7044268B2 (ja) | 2016-11-15 | 2022-03-30 | ガイナー ライフ サイエンシズ,インク. | 自己調節式電解ガス発生器、およびこれを備えるインプラントシステム |
| JP7199632B2 (ja) | 2017-05-04 | 2023-01-06 | ガイナー,インク. | 堅牢なインプラント可能なガス送達装置ならびにそれを含む方法、システムおよび装置 |
| FR3075831B1 (fr) * | 2017-12-22 | 2020-11-13 | Univ Grenoble Alpes | Dispositif implantable de production d'hydrogene |
| US12090300B2 (en) | 2018-05-14 | 2024-09-17 | Giner, Inc. | System and method for controlling oxygen delivery to implanted cells |
| CA3100192C (en) | 2018-05-17 | 2023-03-14 | Giner Life Sciences, Inc. | Electrolytic gas generator with combined lead and gas port terminals |
| EP3856078A4 (en) * | 2018-09-24 | 2022-11-02 | Procyon Technologies LLC | PROCESSES AND SYSTEMS FOR IMPLANTABLE MEDICAL DEVICES AND VASCULARIZING MEMBRANES |
| KR20230117119A (ko) * | 2020-10-30 | 2023-08-07 | 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 | 세포 및 물질을 수용하기 위한 캡슐화 장치에 대한 방법 및 시스템 |
| WO2023205302A2 (en) * | 2022-04-20 | 2023-10-26 | Northwestern University | Oxygen generation system and applications thereof |
| CN116585530B (zh) * | 2023-05-05 | 2024-02-02 | 暨南大学 | 一种高效产氧的叶绿体复合水凝胶及其制备方法与应用 |
Family Cites Families (44)
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| GB2024012B (en) | 1978-04-10 | 1982-07-28 | Johnson & Johnson | Oxygen-generating surgical dressing |
| US4352883A (en) * | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4402694A (en) * | 1981-07-16 | 1983-09-06 | Biotek, Inc. | Body cavity access device containing a hormone source |
| US4631053A (en) * | 1984-03-19 | 1986-12-23 | Taheri Syde A | Oxygenator |
| US4680268A (en) * | 1985-09-18 | 1987-07-14 | Children's Hospital Medical Center | Implantable gas-containing biosensor and method for measuring an analyte such as glucose |
| US5427935A (en) * | 1987-07-24 | 1995-06-27 | The Regents Of The University Of Michigan | Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes |
| US5011472A (en) * | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
| WO1990015526A1 (en) | 1989-06-13 | 1990-12-27 | Agristar, Inc. | Integument and method for culturing and growing organic material |
| US5101814A (en) * | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
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| US5433508A (en) * | 1993-10-19 | 1995-07-18 | Tachi-S Co., Ltd | Powered headrest for automotive seat |
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| US5529066A (en) * | 1994-06-27 | 1996-06-25 | Cb-Carmel Biotechnology Ltd. | Implantable capsule for enhancing cell electric signals |
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| US5702444A (en) * | 1995-09-11 | 1997-12-30 | Struthers, Mehta And Maxwell | Implantable artificial endocrine pancreas |
| AU6854696A (en) * | 1995-09-22 | 1997-04-09 | Gore Hybrid Technologies, Inc. | Improved cell encapsulation device |
| US5855613A (en) * | 1995-10-13 | 1999-01-05 | Islet Sheet Medical, Inc. | Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change |
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| US6368592B1 (en) * | 1998-07-17 | 2002-04-09 | Massachusetts Institute Of Technology | Method of delivering oxygen to cells by electrolyzing water |
| US6148232A (en) * | 1998-11-09 | 2000-11-14 | Elecsys Ltd. | Transdermal drug delivery and analyte extraction |
| WO2000040252A1 (en) * | 1999-01-04 | 2000-07-13 | Biomm, Incorporated | Novel polymer formulations containing perfluorinated compounds for the engineering of cells and tissues for transplantation that improves cell metabolism and survival, and methods for making same |
| WO2000078920A1 (en) | 1999-06-21 | 2000-12-28 | The General Hospital Corporation | Methods and devices for cell culturing and organ assist systems |
| IL134009A (en) | 2000-01-12 | 2011-07-31 | Bo2 Technologies Ltd | Transplant device |
| US8012500B2 (en) | 2000-01-01 | 2011-09-06 | Beta-O2 Technologies Ltd. | Implantable device |
| DE10019339B4 (de) * | 2000-04-19 | 2007-03-08 | Heraeus Kulzer Gmbh | Implantat |
| US20040109302A1 (en) * | 2001-02-28 | 2004-06-10 | Kenji Yoneda | Method of cultivating plant and illuminator for cultivating plant |
| US6767342B1 (en) * | 2001-04-23 | 2004-07-27 | Evelyna D. Cantwell | Oxygen bandage system |
| US7498275B2 (en) | 2001-08-01 | 2009-03-03 | Battelle Memorial Institute | Artificial pulmonary capillary |
| US7332330B2 (en) * | 2001-09-11 | 2008-02-19 | Renamed Biologics, Inc. | Device for maintaining vascularization near an implant |
| EP1488816B1 (en) * | 2002-03-04 | 2017-10-04 | Next 21 K.K. | Closed cell culture system |
| US8532730B2 (en) * | 2006-10-04 | 2013-09-10 | Dexcom, Inc. | Analyte sensor |
| ES2659988T3 (es) * | 2006-11-28 | 2018-03-20 | Beta O2 Technologies Ltd. | Suministro de oxígeno para el transplante celular y la vascularización |
| US8821431B2 (en) | 2007-09-07 | 2014-09-02 | Beta O2 Technologies Ltd. | Air gap for supporting cells |
-
2004
- 2004-11-30 US US11/001,556 patent/US8012500B2/en not_active Expired - Fee Related
-
2005
- 2005-11-27 EP EP05812146A patent/EP1827490A4/en not_active Withdrawn
- 2005-11-27 WO PCT/IL2005/001262 patent/WO2006059322A2/en not_active Ceased
- 2005-11-27 CN CN2005800473254A patent/CN101123984B/zh not_active Expired - Fee Related
- 2005-11-27 JP JP2007544006A patent/JP2008521538A/ja active Pending
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