JP2008518949A5 - - Google Patents
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- Publication number
- JP2008518949A5 JP2008518949A5 JP2007539272A JP2007539272A JP2008518949A5 JP 2008518949 A5 JP2008518949 A5 JP 2008518949A5 JP 2007539272 A JP2007539272 A JP 2007539272A JP 2007539272 A JP2007539272 A JP 2007539272A JP 2008518949 A5 JP2008518949 A5 JP 2008518949A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- dosage unit
- oral dosage
- administered
- aliphatic amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 13
- 229910019142 PO4 Inorganic materials 0.000 claims 8
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 8
- 239000010452 phosphate Substances 0.000 claims 8
- 210000002966 serum Anatomy 0.000 claims 8
- 150000002603 lanthanum Chemical class 0.000 claims 7
- 229960003693 sevelamer Drugs 0.000 claims 7
- ZNSIZMQNQCNRBW-UHFFFAOYSA-N sevelamer Chemical compound NCC=C.ClCC1CO1 ZNSIZMQNQCNRBW-UHFFFAOYSA-N 0.000 claims 7
- 235000013305 food Nutrition 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 239000002694 phosphate binding agent Substances 0.000 claims 5
- 239000002002 slurry Substances 0.000 claims 5
- 239000000725 suspension Substances 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 235000012054 meals Nutrition 0.000 claims 4
- 230000003232 mucoadhesive effect Effects 0.000 claims 3
- 229910017569 La2(CO3)3 Inorganic materials 0.000 claims 2
- 102000006335 Phosphate-Binding Proteins Human genes 0.000 claims 2
- 108010058514 Phosphate-Binding Proteins Proteins 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- NZPIUJUFIFZSPW-UHFFFAOYSA-H lanthanum carbonate Chemical group [La+3].[La+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O NZPIUJUFIFZSPW-UHFFFAOYSA-H 0.000 claims 2
- 229960001633 lanthanum carbonate Drugs 0.000 claims 2
- 229920000083 poly(allylamine) Polymers 0.000 claims 2
- 239000004584 polyacrylic acid Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 241000416162 Astragalus gummifer Species 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 235000015125 Sterculia urens Nutrition 0.000 claims 1
- 240000001058 Sterculia urens Species 0.000 claims 1
- 229920001615 Tragacanth Polymers 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000000196 tragacanth Substances 0.000 claims 1
- 235000010487 tragacanth Nutrition 0.000 claims 1
- 229940116362 tragacanth Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62398504P | 2004-11-01 | 2004-11-01 | |
| PCT/US2005/039365 WO2006050314A2 (en) | 2004-11-01 | 2005-11-01 | Once a day formulation for phosphate binders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008518949A JP2008518949A (ja) | 2008-06-05 |
| JP2008518949A5 true JP2008518949A5 (enExample) | 2008-12-25 |
Family
ID=35735063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007539272A Withdrawn JP2008518949A (ja) | 2004-11-01 | 2005-11-01 | リン酸塩結合剤のための1日1回製剤 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060177415A1 (enExample) |
| EP (1) | EP1812021A2 (enExample) |
| JP (1) | JP2008518949A (enExample) |
| CN (1) | CN101043895A (enExample) |
| AU (1) | AU2005302242A1 (enExample) |
| BR (1) | BRPI0517948A (enExample) |
| CA (1) | CA2586021A1 (enExample) |
| MX (1) | MX2007004940A (enExample) |
| WO (1) | WO2006050314A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| US20060083791A1 (en) | 2002-05-24 | 2006-04-20 | Moerck Rudi E | Rare earth metal compounds methods of making, and methods of using the same |
| JP2008516971A (ja) * | 2004-10-15 | 2008-05-22 | アルテアーナノ,インコーポレーテッド | 錠剤による負荷が軽減されるリン酸塩結合剤 |
| US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
| ITME20040015A1 (it) * | 2004-12-07 | 2005-03-07 | Vincenzo Savica | Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico. |
| WO2006072054A1 (en) * | 2004-12-30 | 2006-07-06 | Genzyme Corporation | Zinc-containing treatments for hyperphosphatemia |
| JP2009507019A (ja) | 2005-09-02 | 2009-02-19 | ジェンザイム・コーポレーション | リン酸塩を除去する方法およびそれに使用される重合体 |
| KR101547925B1 (ko) * | 2005-09-15 | 2015-08-27 | 젠자임 코포레이션 | 아민 중합체에 대한 샤셋 제형 |
| WO2007056405A2 (en) * | 2005-11-08 | 2007-05-18 | Genzyme Corporation | Magnesium-containing polymers for the treatment of hyperphosphatemia |
| US20070104799A1 (en) * | 2005-11-09 | 2007-05-10 | Shire International Licensing B.V. | Treatment of chronic kidney disease (CKD) subjects using lanthanum compounds |
| MY157620A (en) * | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
| JP2009536246A (ja) * | 2006-05-05 | 2009-10-08 | ゲンズイメ コーポレーション | ホスフェート捕捉剤としてのアミン縮合重合体 |
| EP2043627A2 (en) * | 2006-07-05 | 2009-04-08 | Genzyme Corporation | Iron(ii)-containing treatments for hyperphosphatemia |
| CA2658338A1 (en) * | 2006-07-18 | 2008-01-24 | Genzyme Corporation | Amine dendrimers |
| WO2008042222A2 (en) | 2006-09-29 | 2008-04-10 | Genzyme Corporation | Amide dendrimer compositions |
| WO2008076242A1 (en) * | 2006-12-14 | 2008-06-26 | Genzyme Corporation | Amido-amine polymer compositions |
| EP2114376A1 (en) * | 2007-02-23 | 2009-11-11 | Genzyme Corporation | Amine polymer compositions |
| WO2008109095A1 (en) * | 2007-03-08 | 2008-09-12 | Genzyme Corporation | Sulfone polymer compositions |
| US20100166696A1 (en) * | 2007-04-27 | 2010-07-01 | Dhal Pradeep K | Amido-amine dendrimer compositions |
| GB0714670D0 (en) * | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
| GB0720220D0 (en) * | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
| JP2011506449A (ja) * | 2007-12-14 | 2011-03-03 | ジェンザイム コーポレーション | コーティング医薬組成物 |
| US7943597B2 (en) | 2008-04-08 | 2011-05-17 | Cypress Pharmaceutical, Inc. | Phosphate-binding chitosan and uses thereof |
| WO2009126145A1 (en) * | 2008-04-08 | 2009-10-15 | Cypress Pharmaceutical, Inc. | Phosphate-binding chitosan and uses thereof |
| EP2361171A4 (en) * | 2008-09-15 | 2014-11-05 | Shasun Chemicals And Drugs Ltd | PROCESS FOR PREPARING NETWORKED POLYMERS IN A NON-AQUEOUS SOLUTION |
| GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
| GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
| US9181364B2 (en) | 2010-02-24 | 2015-11-10 | Relypsa, Inc. | Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants |
| AU2011252983C1 (en) | 2010-05-12 | 2015-02-19 | Unicycive Therapeutics, Inc. | Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use |
| US8877907B2 (en) | 2010-06-07 | 2014-11-04 | The Johns Hopkins University | Molecularly imprinted polymers |
| US8263119B2 (en) * | 2010-12-01 | 2012-09-11 | Shire Llc | Capsule formulations containing lanthanum compounds |
| EP2548562A1 (de) * | 2011-07-18 | 2013-01-23 | SeBo GmbH | Kombinationstherapie mit Eisen-basierenden Phosphatadsorbern |
| US9744128B2 (en) | 2014-06-05 | 2017-08-29 | Mastix LLC | Method for manufacturing medicated chewing gum without cooling |
| JP6360414B2 (ja) * | 2014-09-15 | 2018-07-18 | 富田製薬株式会社 | ランタン低吸収型経口リン吸着剤 |
| JP6360415B2 (ja) * | 2014-09-30 | 2018-07-18 | 富田製薬株式会社 | ランタン低吸収型経口リン吸着剤 |
| MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| US10245284B2 (en) | 2015-08-19 | 2019-04-02 | Alpex Pharma S.A. | Granular composition for oral administration |
| WO2017072256A1 (en) * | 2015-10-27 | 2017-05-04 | MEDICE Arzneimittel Pütter GmbH & Co. KG | Nicotinamide for lowering phosphate levels in hyperphosphatemia |
| US10765658B2 (en) | 2016-06-22 | 2020-09-08 | Mastix LLC | Oral compositions delivering therapeutically effective amounts of cannabinoids |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3383236A (en) * | 1964-04-17 | 1968-05-14 | Merck & Co Inc | Continuous pharmaceutical film coating process |
| US3431138A (en) * | 1967-07-14 | 1969-03-04 | American Cyanamid Co | Method for coating pharmaceutical forms with methyl cellulose |
| US3539380A (en) * | 1968-01-08 | 1970-11-10 | Upjohn Co | Methylcellulose and polyalkylene glycol coating of solid medicinal dosage forms |
| US4115537A (en) * | 1976-09-07 | 1978-09-19 | American Hospital Supply Corporation | Resin tablet and use thereof in diagnostic tests |
| US4211763A (en) * | 1977-08-08 | 1980-07-08 | The Dow Chemical Company | Anion exchange resin in the determination of thyroid function |
| US4341563A (en) * | 1978-11-17 | 1982-07-27 | Sankyo Company Limited | Protective coating compositions |
| US4543370A (en) * | 1979-11-29 | 1985-09-24 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
| US4302440B1 (en) * | 1980-07-31 | 1986-08-05 | Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof | |
| US4631305A (en) * | 1985-03-22 | 1986-12-23 | The Upjohn Company | Polymeric material as a disintegrant in a compressed tablet |
| US4849227A (en) * | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| US5310572A (en) * | 1987-02-03 | 1994-05-10 | Dow Corning Corporation | Process for forming a coated active agent-containing article |
| US5073380A (en) * | 1987-07-27 | 1991-12-17 | Mcneil-Ppc, Inc. | Oral sustained release pharmaceutical formulation and process |
| US4983398A (en) * | 1987-12-21 | 1991-01-08 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
| US5520932A (en) * | 1988-06-24 | 1996-05-28 | The Upjohn Company | Fine-milled colestipol hydrochloride |
| US5807582A (en) * | 1988-08-26 | 1998-09-15 | Pharmacia & Upjohn Company | Fine-beaded colestipol hydrochloride and pharmaceutically elegant dosage forms made therefrom |
| US5194464A (en) * | 1988-09-27 | 1993-03-16 | Takeda Chemical Industries, Ltd. | Enteric film and preparatoin thereof |
| US4956182A (en) * | 1989-03-16 | 1990-09-11 | Bristol-Myers Company | Direct compression cholestyramine tablet and solvent-free coating therefor |
| US4983399A (en) * | 1989-10-18 | 1991-01-08 | Eastman Kodak Company | Direct compression carrier composition |
| US5262167A (en) * | 1990-12-20 | 1993-11-16 | Basf Corporation | Edible, non-baked low moisture cholestyramine composition |
| US5840339A (en) * | 1991-07-30 | 1998-11-24 | Kunin; Robert | Blood cholesterol reducing pharmaceutical composition |
| US5654003A (en) * | 1992-03-05 | 1997-08-05 | Fuisz Technologies Ltd. | Process and apparatus for making tablets and tablets made therefrom |
| US5487888A (en) * | 1993-05-20 | 1996-01-30 | Geltex, Inc. | Iron-binding polymers for oral administration |
| US5624963A (en) * | 1993-06-02 | 1997-04-29 | Geltex Pharmaceuticals, Inc. | Process for removing bile salts from a patient and compositions therefor |
| US5607669A (en) * | 1994-06-10 | 1997-03-04 | Geltex Pharmaceuticals, Inc. | Amine polymer sequestrant and method of cholesterol depletion |
| US5703188A (en) * | 1993-06-02 | 1997-12-30 | Geltex Pharmaceuticals, Inc. | Process for removing bile salts from a patient and compositions therefor |
| CA2129079C (en) * | 1993-08-03 | 2006-01-17 | Tatsuo Nomura | Orally administrable cholesterol lowering agent |
| US5496545A (en) * | 1993-08-11 | 1996-03-05 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US5667775A (en) * | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US5514273A (en) * | 1993-10-01 | 1996-05-07 | Texaco Inc. | Hydroconversion process employing catalyst with specified pore size distribution |
| JPH09506342A (ja) * | 1993-11-25 | 1997-06-24 | サルテルナテ・ベー・ブイ | 一価カチオンに結合する粒子、並びにナトリウムおよび/またはカリウムイオンを捕捉して除去するための上記粒子の使用および方法 |
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| TW474813B (en) * | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
| JP3355593B2 (ja) * | 1994-08-19 | 2002-12-09 | 信越化学工業株式会社 | 固形腸溶製剤の製造方法 |
| US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
| US5709880A (en) * | 1995-07-10 | 1998-01-20 | Buckman Laboratories International, Inc. | Method of making tabletized ionene polymers |
| TW438608B (en) * | 1995-08-02 | 2001-06-07 | Hisamitsu Pharmaceutical Co | A tablet containing anion exchange resin |
| US6034129A (en) * | 1996-06-24 | 2000-03-07 | Geltex Pharmaceuticals, Inc. | Ionic polymers as anti-infective agents |
| JP4010585B2 (ja) * | 1996-10-15 | 2007-11-21 | 久光製薬株式会社 | 陰イオン交換樹脂を含有する錠剤 |
| US5747067A (en) * | 1996-12-06 | 1998-05-05 | Fmc Corporation | Co-processed products |
| US6203785B1 (en) * | 1996-12-30 | 2001-03-20 | Geltex Pharmaceuticals, Inc. | Poly(diallylamine)-based bile acid sequestrants |
| WO1998042355A1 (en) * | 1997-03-25 | 1998-10-01 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers combined with a calcium supplement for oral administration |
| TW592727B (en) * | 1997-04-04 | 2004-06-21 | Chugai Pharmaceutical Co Ltd | Phosphate-binding polymer preparations |
| US6423754B1 (en) * | 1997-06-18 | 2002-07-23 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with polyallylamine polymers |
| US6726905B1 (en) * | 1997-11-05 | 2004-04-27 | Genzyme Corporation | Poly (diallylamines)-based phosphate binders |
| US5985938A (en) * | 1997-11-05 | 1999-11-16 | Geltex Pharmaceuticals, Inc. | Method for reducing oxalate |
| US6264937B1 (en) * | 1998-01-09 | 2001-07-24 | Geltex Pharmaceuticals, Inc. | Fat-binding polymers |
| DE19917705C1 (de) * | 1999-04-20 | 2000-12-28 | Vitasyn Gmbh | Mittel zur Therapie von Hyperphosphatämie |
| US6180754B1 (en) * | 1999-09-03 | 2001-01-30 | The Dow Chemical Company | Process for producing cross-linked polyallylamine polymer |
| US20020054903A1 (en) * | 1999-10-19 | 2002-05-09 | Joseph Tyler | Direct compression polymer tablet core |
| US6733780B1 (en) * | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| WO2001066607A1 (en) * | 2000-03-09 | 2001-09-13 | Hisamitsu Pharmaceutical Co., Inc. | Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same |
| AU2001241095A1 (en) * | 2000-03-13 | 2001-09-24 | Hisamitsu Pharmaceutical Co. Inc. | Preventives and/or remedies for hyperphosphatemia |
| WO2002085380A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for treating gout and reducing serum uric acid |
| BR0209020A (pt) * | 2001-04-18 | 2004-08-10 | Genzyme Corp | Composição farmacêutica de polialilamina |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7385012B2 (en) * | 2003-11-03 | 2008-06-10 | Ilypsa, Inc. | Polyamine polymers |
| US7449605B2 (en) * | 2003-11-03 | 2008-11-11 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7335795B2 (en) * | 2004-03-22 | 2008-02-26 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| TWM271254U (en) * | 2004-09-10 | 2005-07-21 | Sen Tech Co Ltd | Heat dissipation base and package structure for light-emitting diode |
-
2005
- 2005-10-27 US US11/262,502 patent/US20060177415A1/en not_active Abandoned
- 2005-11-01 WO PCT/US2005/039365 patent/WO2006050314A2/en not_active Ceased
- 2005-11-01 MX MX2007004940A patent/MX2007004940A/es not_active Application Discontinuation
- 2005-11-01 BR BRPI0517948-3A patent/BRPI0517948A/pt not_active IP Right Cessation
- 2005-11-01 EP EP05815376A patent/EP1812021A2/en not_active Withdrawn
- 2005-11-01 CN CNA2005800361687A patent/CN101043895A/zh active Pending
- 2005-11-01 CA CA002586021A patent/CA2586021A1/en not_active Abandoned
- 2005-11-01 JP JP2007539272A patent/JP2008518949A/ja not_active Withdrawn
- 2005-11-01 AU AU2005302242A patent/AU2005302242A1/en not_active Abandoned
-
2009
- 2009-05-14 US US12/466,004 patent/US20090304623A1/en not_active Abandoned
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