JP2006522006A5 - - Google Patents
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- Publication number
- JP2006522006A5 JP2006522006A5 JP2004536184A JP2004536184A JP2006522006A5 JP 2006522006 A5 JP2006522006 A5 JP 2006522006A5 JP 2004536184 A JP2004536184 A JP 2004536184A JP 2004536184 A JP2004536184 A JP 2004536184A JP 2006522006 A5 JP2006522006 A5 JP 2006522006A5
- Authority
- JP
- Japan
- Prior art keywords
- unit dosage
- modafinil
- solid
- solid modafinil
- description
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 claims 30
- 229960001165 modafinil Drugs 0.000 claims 30
- 239000007787 solid Substances 0.000 claims 25
- 229940079593 drug Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical group [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- PKIDMDXXGGEQEM-UHFFFAOYSA-N n-benzhydrylsulfinylacetamide Chemical compound C=1C=CC=CC=1C(S(=O)NC(=O)C)C1=CC=CC=C1 PKIDMDXXGGEQEM-UHFFFAOYSA-N 0.000 claims 2
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 claims 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 229960001021 lactose monohydrate Drugs 0.000 claims 1
- HCWCAKKEBCNQJP-UHFFFAOYSA-N magnesium orthosilicate Chemical compound [Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-] HCWCAKKEBCNQJP-UHFFFAOYSA-N 0.000 claims 1
- 239000000391 magnesium silicate Substances 0.000 claims 1
- 229910052919 magnesium silicate Inorganic materials 0.000 claims 1
- 235000019792 magnesium silicate Nutrition 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 229940032147 starch Drugs 0.000 claims 1
- 239000000454 talc Substances 0.000 claims 1
- 229910052623 talc Inorganic materials 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41039502P | 2002-09-13 | 2002-09-13 | |
| US60/410,395 | 2002-09-13 | ||
| US10/660,058 | 2003-09-11 | ||
| US10/660,058 US20040116532A1 (en) | 2002-09-13 | 2003-09-11 | Pharmaceutical formulations of modafinil |
| PCT/US2003/028651 WO2004024134A1 (en) | 2002-09-13 | 2003-09-12 | Pharmaceutical formulations of modafinil |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006522006A JP2006522006A (ja) | 2006-09-28 |
| JP2006522006A5 true JP2006522006A5 (enExample) | 2006-11-24 |
| JP5039246B2 JP5039246B2 (ja) | 2012-10-03 |
Family
ID=32511269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536184A Expired - Fee Related JP5039246B2 (ja) | 2002-09-13 | 2003-09-12 | モダフィニルの医薬製剤 |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US20040116532A1 (enExample) |
| EP (1) | EP1539126B1 (enExample) |
| JP (1) | JP5039246B2 (enExample) |
| KR (1) | KR101125462B1 (enExample) |
| CN (1) | CN100528151C (enExample) |
| AU (1) | AU2003267156B2 (enExample) |
| BR (1) | BR0314514A (enExample) |
| CA (1) | CA2498260C (enExample) |
| DK (1) | DK1539126T3 (enExample) |
| EA (1) | EA012964B1 (enExample) |
| ES (1) | ES2392580T3 (enExample) |
| IL (1) | IL167054A (enExample) |
| IS (1) | IS2871B (enExample) |
| MX (1) | MXPA05002827A (enExample) |
| NO (1) | NO333614B1 (enExample) |
| NZ (1) | NZ538941A (enExample) |
| PL (1) | PL375833A1 (enExample) |
| PT (1) | PT1539126E (enExample) |
| SI (1) | SI1539126T1 (enExample) |
| TW (1) | TWI335217B (enExample) |
| WO (1) | WO2004024134A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2416792C (en) | 2000-07-27 | 2010-02-09 | Teva Pharmaceutical Industries Ltd. | Crystalline and pure modafinil, and process of preparing the same |
| US20080058424A1 (en) * | 2002-05-23 | 2008-03-06 | Cephalon, Inc. | Novel pharmaceutical formulations of modafinil |
| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US7229644B2 (en) * | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
| US20040116532A1 (en) | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
| WO2004082624A2 (en) * | 2003-03-17 | 2004-09-30 | Neurohealing Pharmaceuticals, Inc. | Modafinil-based neurorehabilitation of impaired neurological function associated with injury |
| US20040253308A1 (en) * | 2003-04-29 | 2004-12-16 | Barr Laboratories, Inc. | Surface-treated modafinil particles |
| US8153159B2 (en) * | 2003-09-18 | 2012-04-10 | Cephalon, Inc. | Modafinil modified release pharmaceutical compositions |
| CN101031290B (zh) * | 2003-09-18 | 2011-09-21 | 赛福伦公司 | 改良释放的莫达非尼药物组合物 |
| WO2005099822A2 (en) * | 2004-04-13 | 2005-10-27 | Cephalon, Inc. | Reduction of drug / drug interactions with modafinil |
| EP1740181A1 (en) * | 2004-04-22 | 2007-01-10 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for the treatment of sexual disorders ii |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| US20060024370A1 (en) | 2004-07-29 | 2006-02-02 | Cephalon France | Modafinil oral lyophilizate |
| US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
| EP1789048A1 (en) * | 2004-09-03 | 2007-05-30 | Boehringer Ingelheim International GmbH | Method for the treatment of attention deficit hyperactivity disorder |
| BRPI0500520A (pt) * | 2005-02-16 | 2006-09-26 | Henry Jun Suzuki | uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas |
| WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
| JP2008531714A (ja) * | 2005-03-04 | 2008-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 不安障害の治療用及び/又は予防用の医薬組成物 |
| CA2599721A1 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of depression |
| CA2608249A1 (en) * | 2005-05-06 | 2006-11-16 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug abuse with flibanserin |
| JP2008540673A (ja) * | 2005-05-19 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 薬剤誘発性性機能不全の治療方法 |
| CA2608713A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of sexual dysfunctions due to medical conditions |
| EP1912650B8 (en) | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
| EP1945214A1 (en) * | 2005-10-29 | 2008-07-23 | Boehringer Ingelheim International GmbH | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| CA2641917A1 (en) * | 2006-02-18 | 2007-08-23 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment of attention deficit hyperactivity disorder comprising flibanserin |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| US20090318469A1 (en) * | 2006-07-14 | 2009-12-24 | Boehringer Ingelheim International Gmbh | Use of Flibanserin for the Treatment of Sexual Disorders in Females |
| CL2007002214A1 (es) * | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| KR20090042967A (ko) * | 2006-08-14 | 2009-05-04 | 베링거 인겔하임 인터내셔날 게엠베하 | 플리반세린 제형 및 이의 제조방법 |
| CN104721168A (zh) * | 2006-08-25 | 2015-06-24 | 贝林格尔·英格海姆国际有限公司 | 控制释放系统及其制造方法 |
| US8173169B2 (en) * | 2007-07-11 | 2012-05-08 | Hikma Pharmaceuticals | Formulation and process for the preparation of modafinil |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| FR2987265B1 (fr) * | 2012-02-28 | 2014-02-28 | Debregeas Et Associes Pharma | Composition pharmaceutique sous forme de sirop a base de modafinil, son procede de fabrication et son application |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1570994A (en) | 1923-11-20 | 1926-01-26 | William A Cook | Spring-forming die |
| US3629393A (en) | 1969-09-11 | 1971-12-21 | Nikken Chemicals Co Ltd | Release-sustaining-tablet |
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
| DE2927988A1 (de) | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 8-phenyl-purine, deren herstellung und deren verwendung als arzneimittel |
| US4431645A (en) | 1982-03-08 | 1984-02-14 | Schering Corporation | Antihypertensive agents |
| HU187215B (en) | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
| US4584285A (en) | 1983-06-02 | 1986-04-22 | Schering Corporation | Antihypertensive agents |
| US4710519A (en) | 1985-09-30 | 1987-12-01 | Basf Corporation | Process for preparing spray dried acetaminophen powder and the powder prepared thereby |
| FR2593809B1 (fr) * | 1986-01-31 | 1988-07-22 | Lafon Labor | Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique |
| US5084277A (en) | 1988-08-30 | 1992-01-28 | Greco John C | Vaginal progesterone tablet |
| FR2663225B1 (fr) * | 1990-06-14 | 1994-11-04 | Lafon Labor | Nouvelle utilisation du modafinil. |
| FR2684875B1 (fr) * | 1991-12-13 | 1995-05-24 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique. |
| FR2697162B1 (fr) * | 1992-10-23 | 1995-01-13 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux. |
| GB9225492D0 (en) | 1992-12-05 | 1993-01-27 | Glaxo Group Ltd | Amine derivatives |
| TW272942B (enExample) | 1993-02-10 | 1996-03-21 | Takeda Pharm Industry Co Ltd | |
| US5843347A (en) * | 1993-03-23 | 1998-12-01 | Laboratoire L. Lafon | Extrusion and freeze-drying method for preparing particles containing an active ingredient |
| FR2702968B1 (fr) | 1993-03-23 | 1995-06-23 | Lafon Labor | Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation . |
| FR2706767B1 (enExample) * | 1993-06-22 | 1995-09-08 | Lafon Labor | |
| FR2707637B1 (fr) * | 1993-06-30 | 1995-10-06 | Lafon Labor | Nouveaux dérivés d'acétamide, leur procédé de préparation et leur utilisation en thérapeutique. |
| US5506248A (en) | 1993-08-02 | 1996-04-09 | Bristol-Myers Squibb Company | Pharmaceutical compositions having good dissolution properties |
| US5618845A (en) * | 1994-10-06 | 1997-04-08 | Cephalon, Inc. | Acetamide derivative having defined particle size |
| SI9500173B (sl) | 1995-05-19 | 2002-02-28 | Lek, | Trofazna farmacevtska oblika s konstantnim in kontroliranim sproščanjem amorfne učinkovine za enkrat dnevno aplikacijo |
| WO1997025989A1 (en) * | 1996-01-19 | 1997-07-24 | Glaxo Group Limited | Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application |
| JPH09208468A (ja) * | 1996-02-02 | 1997-08-12 | Dainippon Pharmaceut Co Ltd | p−クロロ−N−(2−モルホリノエチル)ベンズアミドを含有する錠剤 |
| US5948437A (en) | 1996-05-23 | 1999-09-07 | Zeneca Limited | Pharmaceutical compositions using thiazepine |
| EP2277517A1 (en) | 1996-11-15 | 2011-01-26 | Ajinomoto Co., Inc. | Nateglinide tablet composition |
| GB9714274D0 (en) | 1997-07-08 | 1997-09-10 | Zeneca Ltd | Pharmaceutical composition |
| CA2301883A1 (en) | 1997-09-11 | 1999-03-18 | Nycomed Danmark A/S | Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (nsaids) |
| FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
| HUP0105463A3 (en) | 1998-12-18 | 2003-03-28 | Abbott Lab | Controlled release formulation of divalproex sodium |
| HUP0104606A3 (en) * | 1998-12-18 | 2003-01-28 | Basf Ag | A pharmaceutical mixture comprising a profen |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US7374779B2 (en) | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US20030104048A1 (en) | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6346548B1 (en) * | 1999-08-16 | 2002-02-12 | Cephalon, Inc. | Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue |
| US6455588B1 (en) * | 1999-08-20 | 2002-09-24 | Cephalon, Inc. | Compositions including modafinil for treatment of eating disorders and for appetite stimulation |
| US6204245B1 (en) | 1999-09-17 | 2001-03-20 | The Regents Of The University Of California | Treatment of narcolepsy with immunosuppressants |
| CN1249932A (zh) * | 1999-09-29 | 2000-04-12 | 付俊昌 | 一种莫达芬尼及其光学对映体l及d异构体的新用途 |
| FR2804322B1 (fr) * | 2000-01-31 | 2002-04-19 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un medicament destine a corriger les troubles de la vigilance associes aux myopathies |
| US20010034373A1 (en) | 2000-02-09 | 2001-10-25 | Matthew Miller | Low dose modafinil for enhancement of cognitive function |
| US6670358B2 (en) | 2000-05-16 | 2003-12-30 | Cephalon, Inc. | Substituted thioacetamides |
| US6492396B2 (en) | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
| BR0114814A (pt) * | 2000-10-11 | 2005-01-25 | Cephalon Inc | Composições compreendendo composto de modafinila e seu uso |
| US6489363B2 (en) * | 2000-10-11 | 2002-12-03 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| US6919378B2 (en) * | 2000-10-11 | 2005-07-19 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| KR100911952B1 (ko) | 2000-10-11 | 2009-08-13 | 세파론, 인코포레이티드 | 모다피닐 화합물을 포함하는 조성물 |
| US7141555B2 (en) | 2000-12-19 | 2006-11-28 | Cephalon, Inc. | Modafinil compound and cyclodextrin mixtures |
| ES2281527T3 (es) | 2001-05-25 | 2007-10-01 | Cephalon, Inc. | Formulaciones farmaceuticas solidas que comprenden modafinilo. |
| US7576133B2 (en) * | 2002-03-11 | 2009-08-18 | Carl Henry Lawyer | Methods and compositions for nasal administration of modafinil |
| US7229644B2 (en) | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
| WO2004004692A1 (en) | 2002-07-08 | 2004-01-15 | Ranbaxy Laboratories Limited | Processes for the preparation of oral dosage formulations of modafinil |
| WO2004010979A1 (en) | 2002-07-25 | 2004-02-05 | Ranbaxy Laboratories Limited | Processes for the preparation of oral dosage formulations of modafinil |
| US20040116532A1 (en) * | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
-
2003
- 2003-09-11 US US10/660,058 patent/US20040116532A1/en not_active Abandoned
- 2003-09-12 PT PT03749630T patent/PT1539126E/pt unknown
- 2003-09-12 CA CA2498260A patent/CA2498260C/en not_active Expired - Fee Related
- 2003-09-12 KR KR1020057004198A patent/KR101125462B1/ko not_active Expired - Fee Related
- 2003-09-12 NZ NZ538941A patent/NZ538941A/en not_active IP Right Cessation
- 2003-09-12 BR BR0314514-0A patent/BR0314514A/pt not_active IP Right Cessation
- 2003-09-12 AU AU2003267156A patent/AU2003267156B2/en not_active Ceased
- 2003-09-12 EP EP03749630A patent/EP1539126B1/en not_active Expired - Lifetime
- 2003-09-12 WO PCT/US2003/028651 patent/WO2004024134A1/en not_active Ceased
- 2003-09-12 ES ES03749630T patent/ES2392580T3/es not_active Expired - Lifetime
- 2003-09-12 DK DK03749630.4T patent/DK1539126T3/da active
- 2003-09-12 CN CNB03821749XA patent/CN100528151C/zh not_active Expired - Fee Related
- 2003-09-12 JP JP2004536184A patent/JP5039246B2/ja not_active Expired - Fee Related
- 2003-09-12 PL PL03375833A patent/PL375833A1/xx not_active Application Discontinuation
- 2003-09-12 SI SI200332193T patent/SI1539126T1/sl unknown
- 2003-09-12 EA EA200500488A patent/EA012964B1/ru not_active IP Right Cessation
- 2003-09-12 MX MXPA05002827A patent/MXPA05002827A/es active IP Right Grant
- 2003-09-15 TW TW092125314A patent/TWI335217B/zh not_active IP Right Cessation
-
2005
- 2005-02-22 IL IL167054A patent/IL167054A/en not_active IP Right Cessation
- 2005-02-24 IS IS7714A patent/IS2871B/is unknown
- 2005-02-28 NO NO20051079A patent/NO333614B1/no not_active IP Right Cessation
-
2008
- 2008-04-24 US US12/150,056 patent/US8268892B2/en not_active Expired - Fee Related
-
2012
- 2012-08-21 US US13/590,865 patent/US8686047B2/en not_active Expired - Fee Related
- 2012-08-21 US US13/590,912 patent/US8859621B2/en not_active Expired - Fee Related
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