JP2004525940A5 - - Google Patents
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- Publication number
- JP2004525940A5 JP2004525940A5 JP2002576957A JP2002576957A JP2004525940A5 JP 2004525940 A5 JP2004525940 A5 JP 2004525940A5 JP 2002576957 A JP2002576957 A JP 2002576957A JP 2002576957 A JP2002576957 A JP 2002576957A JP 2004525940 A5 JP2004525940 A5 JP 2004525940A5
- Authority
- JP
- Japan
- Prior art keywords
- duloxetine
- use according
- raloxifene
- hot flashes
- estrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- ZEUITGRIYCTCEM-KRWDZBQOSA-N (S)-duloxetine Chemical compound C1([C@@H](OC=2C3=CC=CC=C3C=CC=2)CCNC)=CC=CS1 ZEUITGRIYCTCEM-KRWDZBQOSA-N 0.000 claims 13
- 229960002866 duloxetine Drugs 0.000 claims 13
- 208000033830 Hot Flashes Diseases 0.000 claims 6
- 206010060800 Hot flush Diseases 0.000 claims 6
- GZUITABIAKMVPG-UHFFFAOYSA-N raloxifene Chemical compound C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 GZUITABIAKMVPG-UHFFFAOYSA-N 0.000 claims 5
- 229960004622 raloxifene Drugs 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 229940011871 estrogen Drugs 0.000 claims 3
- 239000000262 estrogen Substances 0.000 claims 3
- 238000009164 estrogen replacement therapy Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 1
- 229960002119 raloxifene hydrochloride Drugs 0.000 claims 1
- BKXVVCILCIUCLG-UHFFFAOYSA-N raloxifene hydrochloride Chemical group [H+].[Cl-].C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 BKXVVCILCIUCLG-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27989601P | 2001-03-29 | 2001-03-29 | |
| US34808402P | 2002-01-11 | 2002-01-11 | |
| PCT/US2002/005113 WO2002078691A1 (en) | 2001-03-29 | 2002-03-15 | Duloxetine for treatment of hot flashes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004525940A JP2004525940A (ja) | 2004-08-26 |
| JP2004525940A5 true JP2004525940A5 (enExample) | 2005-12-22 |
Family
ID=26959949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002576957A Pending JP2004525940A (ja) | 2001-03-29 | 2002-03-15 | 火照りの処置のためのデュロキセチン |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1383495A1 (enExample) |
| JP (1) | JP2004525940A (enExample) |
| CA (1) | CA2442410A1 (enExample) |
| WO (1) | WO2002078691A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2495452A1 (en) * | 2002-08-14 | 2004-02-26 | Pharmacia & Upjohn Company Llc | Use of reboxetine for the treatment of hot flashes |
| US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
| US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
| US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
| US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
| US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
| US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
| KR20060121178A (ko) * | 2003-12-12 | 2006-11-28 | 일라이 릴리 앤드 캄파니 | 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제 |
| US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| WO2007034503A2 (en) * | 2005-06-20 | 2007-03-29 | Cadila Healthcare Limited | Controlled release dosage formulation of duloxetine |
| CN107249615B (zh) * | 2015-04-07 | 2021-02-05 | 株式会社明治 | 潮热抑制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508276A (en) * | 1994-07-18 | 1996-04-16 | Eli Lilly And Company | Duloxetine enteric pellets |
| WO1997033880A1 (en) * | 1996-03-11 | 1997-09-18 | Eli Lilly And Company | Methods of treating or preventing interstitial cystitis |
| KR20010015918A (ko) * | 1998-03-02 | 2001-02-26 | 피터 지. 스트링거 | 안면홍조를 감소시키기 위한 플루옥세틴 히드로클로라이드 |
-
2002
- 2002-03-15 EP EP02707828A patent/EP1383495A1/en not_active Withdrawn
- 2002-03-15 CA CA002442410A patent/CA2442410A1/en not_active Abandoned
- 2002-03-15 JP JP2002576957A patent/JP2004525940A/ja active Pending
- 2002-03-15 WO PCT/US2002/005113 patent/WO2002078691A1/en not_active Ceased
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