JP2008517915A - Ｓ１ｐ受容体アゴニストとしての２−（アリール）アザシクリルメチルカルボキシレート、スルホネート、ホスホネート、ホスフィネート及びヘテロ環 - Google Patents

Ｓ１ｐ受容体アゴニストとしての２−（アリール）アザシクリルメチルカルボキシレート、スルホネート、ホスホネート、ホスフィネート及びヘテロ環 Download PDF

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JP2008517915A
JP2008517915A JP2007538016A JP2007538016A JP2008517915A JP 2008517915 A JP2008517915 A JP 2008517915A JP 2007538016 A JP2007538016 A JP 2007538016A JP 2007538016 A JP2007538016 A JP 2007538016A JP 2008517915 A JP2008517915 A JP 2008517915A
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disease
group
phenyl
alkoxy
compound
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JP2008517915A5 (https=
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ヘイル，ジエフリー・ジヨン
ヤン，リン
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Merck and Co Inc
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Merck and Co Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Dermatology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Transplantation (AREA)
  • Endocrinology (AREA)
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JP2007538016A 2004-10-22 2005-10-18 Ｓ１ｐ受容体アゴニストとしての２−（アリール）アザシクリルメチルカルボキシレート、スルホネート、ホスホネート、ホスフィネート及びヘテロ環 Pending JP2008517915A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62131304P 2004-10-22 2004-10-22
PCT/US2005/037652 WO2006047195A2 (en) 2004-10-22 2005-10-18 2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as s1p receptor agonists

Publications (2)

Publication Number Publication Date
JP2008517915A true JP2008517915A (ja) 2008-05-29
JP2008517915A5 JP2008517915A5 (https=) 2008-11-27

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JP2007538016A Pending JP2008517915A (ja) 2004-10-22 2005-10-18 Ｓ１ｐ受容体アゴニストとしての２−（アリール）アザシクリルメチルカルボキシレート、スルホネート、ホスホネート、ホスフィネート及びヘテロ環

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Country Link
US (1) US7659294B2 (https=)
EP (1) EP1804793A4 (https=)
JP (1) JP2008517915A (https=)
CN (1) CN101043887A (https=)
AU (1) AU2005299851B2 (https=)
CA (1) CA2583681A1 (https=)
WO (1) WO2006047195A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
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JP2012001502A (ja) * 2010-06-18 2012-01-05 Jnc Corp ５員環を有する化合物、液晶組成物および液晶表示素子
JP2012512829A (ja) * 2008-12-18 2012-06-07 メルク セローノ ソシエテ アノニム 多発性硬化症の治療に有用なオキサジアゾール縮合複素環式誘導体
JP2012528086A (ja) * 2009-05-27 2012-11-12 レオ ファーマ アクティーゼルスカブ 新規のカルシウム感知受容体調節化合物およびその医薬用途
JP2013503141A (ja) * 2009-08-31 2013-01-31 アボツト・ヘルスケア・プロダクツ・ベー・ブイ Ｓ１ｐモジュレーターとしての（チオ）モルホリン誘導体
JP2023502355A (ja) * 2019-11-20 2023-01-24 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を処置する方法

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AR061841A1 (es) 2006-09-07 2008-09-24 Actelion Pharmaceuticals Ltd Derivados de tiofen-oxadiazoles, agonistas del receptor s1p1/edg1, composiciones farmaceuticas que los contienen y usos como agentes inmunomoduladores.
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AU2008240773B2 (en) * 2007-04-19 2013-10-03 Glaxo Group Limited Oxadiazole substituted indazole derivatives for use as sphingosine 1-phosphate (S1P) agonists
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KR20100092473A (ko) 2007-11-01 2010-08-20 액테리온 파마슈티칼 리미티드 신규한 피리미딘 유도체
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CN105503882B (zh) 2010-03-03 2019-07-05 艾尼纳制药公司 制备s1p1受体调节剂及其晶体形式的方法
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