JP2008517613A5 - - Google Patents

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Publication number
JP2008517613A5
JP2008517613A5 JP2007538421A JP2007538421A JP2008517613A5 JP 2008517613 A5 JP2008517613 A5 JP 2008517613A5 JP 2007538421 A JP2007538421 A JP 2007538421A JP 2007538421 A JP2007538421 A JP 2007538421A JP 2008517613 A5 JP2008517613 A5 JP 2008517613A5
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JP
Japan
Prior art keywords
jak2
variant
sequence
seq
mutation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007538421A
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English (en)
Japanese (ja)
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JP5090171B2 (ja
JP2008517613A (ja
Filing date
Publication date
Priority claimed from FR0411480A external-priority patent/FR2877013A1/fr
Application filed filed Critical
Publication of JP2008517613A publication Critical patent/JP2008517613A/ja
Publication of JP2008517613A5 publication Critical patent/JP2008517613A5/ja
Application granted granted Critical
Publication of JP5090171B2 publication Critical patent/JP5090171B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007538421A 2004-10-27 2005-10-26 真性赤血球増加症に関与するｊａｋ２の変異の識別方法 Expired - Lifetime JP5090171B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0411480A FR2877013A1 (fr) 2004-10-27 2004-10-27 Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez
FR0411480 2004-10-27
PCT/EP2005/055586 WO2006045827A1 (fr) 2004-10-27 2005-10-26 Identification d'une mutation de jak2 impliquée dans la polyglobulie de vaquez

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009155912A Division JP5290884B2 (ja) 2004-10-27 2009-06-30 真性赤血球増加症に関与するｊａｋ２の変異の識別方法

Publications (3)

Publication Number Publication Date
JP2008517613A JP2008517613A (ja) 2008-05-29
JP2008517613A5 true JP2008517613A5 (https=) 2009-03-05
JP5090171B2 JP5090171B2 (ja) 2012-12-05

Family

ID=34953071

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2007538421A Expired - Lifetime JP5090171B2 (ja) 2004-10-27 2005-10-26 真性赤血球増加症に関与するｊａｋ２の変異の識別方法
JP2009155912A Expired - Lifetime JP5290884B2 (ja) 2004-10-27 2009-06-30 真性赤血球増加症に関与するｊａｋ２の変異の識別方法
JP2013003374A Expired - Lifetime JP6103691B2 (ja) 2004-10-27 2013-01-11 真性赤血球増加症に関与するｊａｋ２の変異の識別方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009155912A Expired - Lifetime JP5290884B2 (ja) 2004-10-27 2009-06-30 真性赤血球増加症に関与するｊａｋ２の変異の識別方法
JP2013003374A Expired - Lifetime JP6103691B2 (ja) 2004-10-27 2013-01-11 真性赤血球増加症に関与するｊａｋ２の変異の識別方法

Country Status (20)

Country Link
US (9) US7781199B2 (https=)
EP (2) EP1895000A1 (https=)
JP (3) JP5090171B2 (https=)
KR (1) KR101203003B1 (https=)
CN (1) CN101072870B (https=)
AT (1) ATE382082T1 (https=)
AU (1) AU2005298636B2 (https=)
BR (1) BRPI0517398B8 (https=)
CA (3) CA2647086C (https=)
DE (1) DE602005004008T2 (https=)
DK (1) DK1692281T3 (https=)
ES (1) ES2296229T3 (https=)
FR (1) FR2877013A1 (https=)
IL (1) IL182761A0 (https=)
MX (1) MX2007005174A (https=)
PL (1) PL1692281T3 (https=)
PT (1) PT1692281E (https=)
SI (1) SI1692281T1 (https=)
WO (1) WO2006045827A1 (https=)
ZA (1) ZA200703433B (https=)

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WO2011067373A1 (fr) * 2009-12-04 2011-06-09 Assistance Publique - Hopitaux De Paris Methode de detection d'une polyglobulie chez un chien
AU2011214254B2 (en) * 2010-02-10 2016-06-09 Genon Biotechnologies Oy Dual activity kinase domains and uses thereof
US20120021413A1 (en) * 2010-04-30 2012-01-26 Arkray, Inc. Method for Detecting Mutation in Exon 12 of JAK2 Gene, and Nucleic Acid Probe and Kit Therefor
US10174364B2 (en) * 2010-07-16 2019-01-08 Stichting Vu-Vumc Method of analysing a blood sample of a subject for the presence of a disease marker
US10174365B2 (en) 2011-03-18 2019-01-08 Stichting Vu-Vumc Method of analysing a blood sample of a subject for the presence of a disease marker
JP2013017395A (ja) * 2011-07-07 2013-01-31 Toyobo Co Ltd 骨髄増殖性疾患に関する遺伝子変異を検出するためのプローブおよび該プローブを用いた遺伝子変異の検出方法
GB201116876D0 (en) 2011-09-30 2011-11-16 Epistem Ltd Mutational analysis of JAK2
CN103243153B (zh) * 2012-02-10 2014-11-05 复旦大学附属华山医院 Jak2 v617f突变的检测应用
WO2014068072A1 (en) 2012-10-31 2014-05-08 Institut Gustave-Roussy Identification, assessment and therapy of essential thrombocythemia with resistance to jak2 inhibitors
EP2917341B1 (en) 2012-11-08 2017-09-27 Centre National de la Recherche Scientifique (CNRS) New phosphodeoxyribosyltransferase mutant enzymes and uses thereof
WO2014074847A1 (en) 2012-11-09 2014-05-15 The Johns Hopkins University A genetic assay to determine prognosis in polycythemia vera patients
US9375485B2 (en) 2012-12-07 2016-06-28 Geron Corporation Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms
RS59363B1 (sr) 2012-12-07 2019-11-29 Geron Corp Upotreba inhibitora telomeraze imetelstata za lečenje mijelofibroze
EP2997436B1 (en) 2013-05-16 2022-02-16 Mobelisk Group, LLC Modular tablet case
WO2016097773A1 (en) 2014-12-19 2016-06-23 Children's Cancer Institute Therapeutic iap antagonists for treating proliferative disorders
US20180318303A1 (en) * 2015-04-15 2018-11-08 Promedior, Inc. Methods for treating myeloproliferative disorders
MX389138B (es) 2015-04-23 2025-03-20 Quest Diagnostics Invest Inc Metodos y composiciones para la deteccion de mutaciones de calr en enfermedades mieloproliferativas.
CN108348578B (zh) 2015-08-04 2022-08-09 阿塞勒隆制药公司 用于治疗骨髓增生性病症的方法
CN105441573A (zh) * 2016-01-11 2016-03-30 武汉海吉力生物科技有限公司 用于检测人类jak2基因v617f突变的引物、探针及试剂盒
EP3468585A2 (en) * 2016-06-10 2019-04-17 IO Biotech APS Calr and jak2 vaccine compositions
JP7316261B2 (ja) 2017-07-28 2023-07-27 ジェロン・コーポレーション 骨髄異形成症候群の治療方法
KR20250074692A (ko) 2018-11-29 2025-05-27 제론 코포레이션 골수이형성 증후군을 치료하는 방법
CR20220220A (es) 2019-11-18 2022-09-20 Janssen Biotech Inc Vacunas basadas en calr y jak2 mutantes y sus usos
US11691971B2 (en) 2020-06-19 2023-07-04 Incyte Corporation Naphthyridinone compounds as JAK2 V617F inhibitors
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
CR20230057A (es) 2020-07-02 2023-08-15 Incyte Corp Compuestos tríciclicos de urea como inhibidores de jak2 v617f
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
AR125273A1 (es) 2021-02-25 2023-07-05 Incyte Corp Lactamas espirocíclicas como inhibidores de jak2 v617f
AU2023235313A1 (en) 2022-03-17 2024-10-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors

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