JP2008515770A5 - - Google Patents
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- JP2008515770A5 JP2008515770A5 JP2007519691A JP2007519691A JP2008515770A5 JP 2008515770 A5 JP2008515770 A5 JP 2008515770A5 JP 2007519691 A JP2007519691 A JP 2007519691A JP 2007519691 A JP2007519691 A JP 2007519691A JP 2008515770 A5 JP2008515770 A5 JP 2008515770A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- peptide
- prevention
- optionally
- residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 125000001183 hydrocarbyl group Chemical group 0.000 claims 6
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 claims 6
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- LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 claims 4
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 3
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- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 3
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- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 3
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 3
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 3
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 3
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- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 3
- SNDPXSYFESPGGJ-UHFFFAOYSA-N L-norVal-OH Natural products CCCC(N)C(O)=O SNDPXSYFESPGGJ-UHFFFAOYSA-N 0.000 claims 3
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 3
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 3
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims 3
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- 239000004472 Lysine Substances 0.000 claims 3
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- FPDYKABXINADKS-LURJTMIESA-N (2s)-2-(methylazaniumyl)hexanoate Chemical compound CCCC[C@H](NC)C(O)=O FPDYKABXINADKS-LURJTMIESA-N 0.000 claims 2
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- 239000003085 diluting agent Substances 0.000 claims 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 claims 1
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- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04016239 | 2004-07-09 | ||
| PCT/EP2005/007134 WO2006005455A2 (en) | 2004-07-09 | 2005-07-01 | Amino, amino acid or peptide conjugates of retinoic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008515770A JP2008515770A (ja) | 2008-05-15 |
| JP2008515770A5 true JP2008515770A5 (enExample) | 2011-09-29 |
Family
ID=35062952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519691A Pending JP2008515770A (ja) | 2004-07-09 | 2005-07-01 | レチノイン酸のアミノ、アミノ酸またはペプチド結合体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20070270472A1 (enExample) |
| EP (1) | EP1765773A2 (enExample) |
| JP (1) | JP2008515770A (enExample) |
| KR (1) | KR20070038509A (enExample) |
| CN (1) | CN101048375B (enExample) |
| BR (1) | BRPI0513145A (enExample) |
| WO (1) | WO2006005455A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5572318B2 (ja) * | 2005-12-30 | 2014-08-13 | ルバンス セラピュティックス インク． | 局所投与用アルギニンヘテロマー |
| EP2491928A2 (en) * | 2007-10-19 | 2012-08-29 | The University of Tokyo | Therapeutic agent for vitiligo and method of accelerating pigmentation |
| CN102665706A (zh) * | 2009-09-29 | 2012-09-12 | 株式会社资生堂 | 抗氧化组合物 |
| CN103327965B (zh) * | 2011-01-25 | 2017-07-18 | 宝洁公司 | 脂质体和包含脂质体的个人护理组合物 |
| KR101224809B1 (ko) * | 2012-04-24 | 2013-01-21 | 주식회사 아이피어리스 | 레티노산 유도체, 이의 제조 방법 및 이를 포함하는 화장품 조성물 |
| EP2745904B1 (en) | 2012-12-21 | 2015-12-16 | Dionex Corporation | HILIC/Anion-Exchange/Cation-Exchange Multimodal Media |
| US9511144B2 (en) | 2013-03-14 | 2016-12-06 | The Proctor & Gamble Company | Cosmetic compositions and methods providing enhanced penetration of skin care actives |
| CN105530912B (zh) * | 2013-08-15 | 2018-04-13 | 玫琳凯有限公司 | 用于处理皱纹的局部皮肤用组合物 |
| FR3054130B1 (fr) * | 2016-07-22 | 2019-04-26 | Syntivia | Procede de traitement cosmetique de la peau |
| KR102093209B1 (ko) * | 2017-05-11 | 2020-03-25 | (주)케어젠 | 이소트레티노인과 펩타이드의 결합체 |
| EP3630083A4 (en) * | 2017-05-23 | 2021-03-10 | The Regents of The University of Michigan | DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND THEIR USES |
| CN110785161B (zh) | 2017-06-23 | 2023-06-20 | 宝洁公司 | 用于改善皮肤外观的组合物和方法 |
| EP3817717A1 (en) | 2018-07-03 | 2021-05-12 | The Procter & Gamble Company | Method of treating a skin condition |
| KR102076178B1 (ko) * | 2018-07-18 | 2020-02-11 | 주식회사 코리아나화장품 | 초유 및 오르니틴을 유효성분으로 함유하는 피부 주름 개선용 화장료 조성물 |
| KR20210092483A (ko) | 2020-01-16 | 2021-07-26 | 맹창남 | 모발 및 두피상태 개선용 화장료 조성물 |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| CN117384073A (zh) * | 2022-07-11 | 2024-01-12 | 南京毓浠医药技术有限公司 | 一种维a酸醇胺类复合物及其制备方法和应用 |
| CN118121574A (zh) * | 2022-12-02 | 2024-06-04 | 南京毓浠医药技术有限公司 | 一种含维a酸组合物及其制备方法和用途 |
| KR20250136628A (ko) | 2024-03-08 | 2025-09-16 | 주식회사 에이치엔컴퍼니 | 모발 개선용 화장료 조성물 |
| CN118126119B (zh) * | 2024-05-10 | 2024-08-06 | 荷本世新(北京)生物科技有限公司 | 维a酸多肽衍生物及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950418A (en) * | 1970-02-02 | 1976-04-13 | Hoffmann-La Roche Inc. | Vitamin A acid amides |
| CH529742A (de) * | 1970-02-02 | 1972-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von Vitamin-A-Säureamiden |
| DE2300107C2 (de) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
| US4108880A (en) * | 1975-11-03 | 1978-08-22 | Johnson & Johnson | Esters of retinoic acid |
| CH661516A5 (de) * | 1983-12-08 | 1987-07-31 | Hoffmann La Roche | Phenylnonatetraenoylzuckerderivate. |
| US5559149A (en) * | 1990-01-29 | 1996-09-24 | Johnson & Johnson Consumer Products, Inc. | Skin care compositions containing retinoids |
| DE4032187C2 (de) * | 1990-10-10 | 1995-03-30 | Gradinger F Hermes Pharma | N-Retinoyl-L-aminomercapto-Verbindungen und Zwischenprodukte, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19523079A1 (de) * | 1995-06-26 | 1997-01-02 | Basf Ag | Ester und Amide der 9(Z)-Retinsäure |
| EP1068181B1 (en) * | 1998-03-30 | 2003-05-07 | Lg Chemical Limited | Polyethoxylated retinamide derivatives and process for preparing the same |
| EP1159952B1 (en) * | 1999-03-02 | 2009-01-14 | Kyowa Hakko Kogyo Co., Ltd. | N-Acetylhydroxyproline for improving the moisture retention function of the epidermis |
| JP2001039997A (ja) * | 1999-07-29 | 2001-02-13 | Lion Corp | 安定化されたレチノイン酸類の誘導体、ならびにそれらを含有する外用剤組成物 |
| JP4221547B2 (ja) * | 2001-01-26 | 2009-02-12 | ライオン株式会社 | レチノイン酸類またはその誘導体を含有する組成物 |
| KR100439627B1 (ko) * | 2001-06-18 | 2004-07-12 | 주식회사 엘지생활건강 | 피부주름 예방 및 치료용 조성물 |
| ATE385769T1 (de) * | 2002-07-25 | 2008-03-15 | Lion Corp | Topisches präparat |
| CN1197847C (zh) * | 2002-09-02 | 2005-04-20 | 复旦大学 | 化合物n－全反式维甲酰胺衍生物及其制备方法和应用 |
| KR101045658B1 (ko) * | 2003-11-17 | 2011-07-01 | 쎄데르마 | 테트라펩티드 및 트리펩티드 혼합물을 포함하는 조성물 |
-
2005
- 2005-07-01 WO PCT/EP2005/007134 patent/WO2006005455A2/en not_active Ceased
- 2005-07-01 US US11/631,322 patent/US20070270472A1/en not_active Abandoned
- 2005-07-01 EP EP05755911A patent/EP1765773A2/en not_active Withdrawn
- 2005-07-01 JP JP2007519691A patent/JP2008515770A/ja active Pending
- 2005-07-01 BR BRPI0513145-6A patent/BRPI0513145A/pt not_active IP Right Cessation
- 2005-07-01 CN CN200580022901XA patent/CN101048375B/zh not_active Expired - Fee Related
- 2005-07-01 KR KR1020077000471A patent/KR20070038509A/ko not_active Ceased
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