BRPI0513145A - conjugados de amino, aminoácido ou peptìdeo de ácido retinóico - Google Patents
conjugados de amino, aminoácido ou peptìdeo de ácido retinóicoInfo
- Publication number
- BRPI0513145A BRPI0513145A BRPI0513145-6A BRPI0513145A BRPI0513145A BR PI0513145 A BRPI0513145 A BR PI0513145A BR PI0513145 A BRPI0513145 A BR PI0513145A BR PI0513145 A BRPI0513145 A BR PI0513145A
- Authority
- BR
- Brazil
- Prior art keywords
- amino
- acid
- peptide conjugates
- retinoic acid
- retinoic
- Prior art date
Links
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title abstract 2
- -1 amino, amino Chemical group 0.000 title abstract 2
- 229930002330 retinoic acid Natural products 0.000 title abstract 2
- 229960001727 tretinoin Drugs 0.000 title abstract 2
- 239000000863 peptide conjugate Substances 0.000 title 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 125000001444 retinoyl group Chemical group O=C([*])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 230000009759 skin aging Effects 0.000 abstract 1
- 230000008719 thickening Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04016239 | 2004-07-09 | ||
| PCT/EP2005/007134 WO2006005455A2 (en) | 2004-07-09 | 2005-07-01 | Amino, amino acid or peptide conjugates of retinoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0513145A true BRPI0513145A (pt) | 2008-04-29 |
Family
ID=35062952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513145-6A BRPI0513145A (pt) | 2004-07-09 | 2005-07-01 | conjugados de amino, aminoácido ou peptìdeo de ácido retinóico |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20070270472A1 (enExample) |
| EP (1) | EP1765773A2 (enExample) |
| JP (1) | JP2008515770A (enExample) |
| KR (1) | KR20070038509A (enExample) |
| CN (1) | CN101048375B (enExample) |
| BR (1) | BRPI0513145A (enExample) |
| WO (1) | WO2006005455A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5572318B2 (ja) * | 2005-12-30 | 2014-08-13 | ルバンス セラピュティックス インク． | 局所投与用アルギニンヘテロマー |
| EP2491928A2 (en) * | 2007-10-19 | 2012-08-29 | The University of Tokyo | Therapeutic agent for vitiligo and method of accelerating pigmentation |
| CN102665706A (zh) * | 2009-09-29 | 2012-09-12 | 株式会社资生堂 | 抗氧化组合物 |
| CN103327965B (zh) * | 2011-01-25 | 2017-07-18 | 宝洁公司 | 脂质体和包含脂质体的个人护理组合物 |
| KR101224809B1 (ko) * | 2012-04-24 | 2013-01-21 | 주식회사 아이피어리스 | 레티노산 유도체, 이의 제조 방법 및 이를 포함하는 화장품 조성물 |
| EP2745904B1 (en) | 2012-12-21 | 2015-12-16 | Dionex Corporation | HILIC/Anion-Exchange/Cation-Exchange Multimodal Media |
| US9511144B2 (en) | 2013-03-14 | 2016-12-06 | The Proctor & Gamble Company | Cosmetic compositions and methods providing enhanced penetration of skin care actives |
| CN105530912B (zh) * | 2013-08-15 | 2018-04-13 | 玫琳凯有限公司 | 用于处理皱纹的局部皮肤用组合物 |
| FR3054130B1 (fr) * | 2016-07-22 | 2019-04-26 | Syntivia | Procede de traitement cosmetique de la peau |
| KR102093209B1 (ko) * | 2017-05-11 | 2020-03-25 | (주)케어젠 | 이소트레티노인과 펩타이드의 결합체 |
| EP3630083A4 (en) * | 2017-05-23 | 2021-03-10 | The Regents of The University of Michigan | DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND THEIR USES |
| CN110785161B (zh) | 2017-06-23 | 2023-06-20 | 宝洁公司 | 用于改善皮肤外观的组合物和方法 |
| EP3817717A1 (en) | 2018-07-03 | 2021-05-12 | The Procter & Gamble Company | Method of treating a skin condition |
| KR102076178B1 (ko) * | 2018-07-18 | 2020-02-11 | 주식회사 코리아나화장품 | 초유 및 오르니틴을 유효성분으로 함유하는 피부 주름 개선용 화장료 조성물 |
| KR20210092483A (ko) | 2020-01-16 | 2021-07-26 | 맹창남 | 모발 및 두피상태 개선용 화장료 조성물 |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| CN117384073A (zh) * | 2022-07-11 | 2024-01-12 | 南京毓浠医药技术有限公司 | 一种维a酸醇胺类复合物及其制备方法和应用 |
| CN118121574A (zh) * | 2022-12-02 | 2024-06-04 | 南京毓浠医药技术有限公司 | 一种含维a酸组合物及其制备方法和用途 |
| KR20250136628A (ko) | 2024-03-08 | 2025-09-16 | 주식회사 에이치엔컴퍼니 | 모발 개선용 화장료 조성물 |
| CN118126119B (zh) * | 2024-05-10 | 2024-08-06 | 荷本世新(北京)生物科技有限公司 | 维a酸多肽衍生物及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950418A (en) * | 1970-02-02 | 1976-04-13 | Hoffmann-La Roche Inc. | Vitamin A acid amides |
| CH529742A (de) * | 1970-02-02 | 1972-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von Vitamin-A-Säureamiden |
| DE2300107C2 (de) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
| US4108880A (en) * | 1975-11-03 | 1978-08-22 | Johnson & Johnson | Esters of retinoic acid |
| CH661516A5 (de) * | 1983-12-08 | 1987-07-31 | Hoffmann La Roche | Phenylnonatetraenoylzuckerderivate. |
| US5559149A (en) * | 1990-01-29 | 1996-09-24 | Johnson & Johnson Consumer Products, Inc. | Skin care compositions containing retinoids |
| DE4032187C2 (de) * | 1990-10-10 | 1995-03-30 | Gradinger F Hermes Pharma | N-Retinoyl-L-aminomercapto-Verbindungen und Zwischenprodukte, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19523079A1 (de) * | 1995-06-26 | 1997-01-02 | Basf Ag | Ester und Amide der 9(Z)-Retinsäure |
| EP1068181B1 (en) * | 1998-03-30 | 2003-05-07 | Lg Chemical Limited | Polyethoxylated retinamide derivatives and process for preparing the same |
| EP1159952B1 (en) * | 1999-03-02 | 2009-01-14 | Kyowa Hakko Kogyo Co., Ltd. | N-Acetylhydroxyproline for improving the moisture retention function of the epidermis |
| JP2001039997A (ja) * | 1999-07-29 | 2001-02-13 | Lion Corp | 安定化されたレチノイン酸類の誘導体、ならびにそれらを含有する外用剤組成物 |
| JP4221547B2 (ja) * | 2001-01-26 | 2009-02-12 | ライオン株式会社 | レチノイン酸類またはその誘導体を含有する組成物 |
| KR100439627B1 (ko) * | 2001-06-18 | 2004-07-12 | 주식회사 엘지생활건강 | 피부주름 예방 및 치료용 조성물 |
| ATE385769T1 (de) * | 2002-07-25 | 2008-03-15 | Lion Corp | Topisches präparat |
| CN1197847C (zh) * | 2002-09-02 | 2005-04-20 | 复旦大学 | 化合物n－全反式维甲酰胺衍生物及其制备方法和应用 |
| KR101045658B1 (ko) * | 2003-11-17 | 2011-07-01 | 쎄데르마 | 테트라펩티드 및 트리펩티드 혼합물을 포함하는 조성물 |
-
2005
- 2005-07-01 WO PCT/EP2005/007134 patent/WO2006005455A2/en not_active Ceased
- 2005-07-01 US US11/631,322 patent/US20070270472A1/en not_active Abandoned
- 2005-07-01 EP EP05755911A patent/EP1765773A2/en not_active Withdrawn
- 2005-07-01 JP JP2007519691A patent/JP2008515770A/ja active Pending
- 2005-07-01 BR BRPI0513145-6A patent/BRPI0513145A/pt not_active IP Right Cessation
- 2005-07-01 CN CN200580022901XA patent/CN101048375B/zh not_active Expired - Fee Related
- 2005-07-01 KR KR1020077000471A patent/KR20070038509A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006005455A2 (en) | 2006-01-19 |
| CN101048375A (zh) | 2007-10-03 |
| WO2006005455A3 (en) | 2008-02-07 |
| US20070270472A1 (en) | 2007-11-22 |
| JP2008515770A (ja) | 2008-05-15 |
| EP1765773A2 (en) | 2007-03-28 |
| KR20070038509A (ko) | 2007-04-10 |
| CN101048375B (zh) | 2012-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2313 DE 05-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |