JP2008512451A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008512451A5 JP2008512451A5 JP2007531131A JP2007531131A JP2008512451A5 JP 2008512451 A5 JP2008512451 A5 JP 2008512451A5 JP 2007531131 A JP2007531131 A JP 2007531131A JP 2007531131 A JP2007531131 A JP 2007531131A JP 2008512451 A5 JP2008512451 A5 JP 2008512451A5
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- acid
- hypophosphite
- formula
- process according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Natural products CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 5
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 5
- 239000002253 acid Substances 0.000 claims 4
- KZMGYPLQYOPHEL-UHFFFAOYSA-N Boron trifluoride etherate Chemical compound FB(F)F.CCOCC KZMGYPLQYOPHEL-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- ACVYVLVWPXVTIT-UHFFFAOYSA-M phosphinate Chemical compound [O-][PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-M 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- PYOKUURKVVELLB-UHFFFAOYSA-N trimethyl orthoformate Chemical compound COC(OC)OC PYOKUURKVVELLB-UHFFFAOYSA-N 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- NDQXKKFRNOPRDW-UHFFFAOYSA-N 1,1,1-triethoxyethane Chemical compound CCOC(C)(OCC)OCC NDQXKKFRNOPRDW-UHFFFAOYSA-N 0.000 claims 1
- HDPNBNXLBDFELL-UHFFFAOYSA-N 1,1,1-trimethoxyethane Chemical compound COC(C)(OC)OC HDPNBNXLBDFELL-UHFFFAOYSA-N 0.000 claims 1
- KWSLGOVYXMQPPX-UHFFFAOYSA-N 5-[3-(trifluoromethyl)phenyl]-2h-tetrazole Chemical compound FC(F)(F)C1=CC=CC(C2=NNN=N2)=C1 KWSLGOVYXMQPPX-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- GJYJYFHBOBUTBY-UHFFFAOYSA-N alpha-camphorene Chemical group CC(C)=CCCC(=C)C1CCC(CCC=C(C)C)=CC1 GJYJYFHBOBUTBY-UHFFFAOYSA-N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229940098779 methanesulfonic acid Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910001380 potassium hypophosphite Inorganic materials 0.000 claims 1
- CRGPNLUFHHUKCM-UHFFFAOYSA-M potassium phosphinate Chemical compound [K+].[O-]P=O CRGPNLUFHHUKCM-UHFFFAOYSA-M 0.000 claims 1
- 229910001379 sodium hypophosphite Inorganic materials 0.000 claims 1
- 125000003944 tolyl group Chemical group 0.000 claims 1
- GKASDNZWUGIAMG-UHFFFAOYSA-N triethyl orthoformate Chemical compound CCOC(OCC)OCC GKASDNZWUGIAMG-UHFFFAOYSA-N 0.000 claims 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0402199A SE0402199D0 (sv) | 2004-09-13 | 2004-09-13 | New process I |
| PCT/SE2005/001316 WO2006031180A1 (en) | 2004-09-13 | 2005-09-12 | Process for preparation of alkyl phosphinates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008512451A JP2008512451A (ja) | 2008-04-24 |
| JP2008512451A5 true JP2008512451A5 (enExample) | 2008-10-30 |
Family
ID=33157526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007531131A Pending JP2008512451A (ja) | 2004-09-13 | 2005-09-12 | ホスフィン酸アルキルの製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7557234B2 (enExample) |
| EP (1) | EP1791851B1 (enExample) |
| JP (1) | JP2008512451A (enExample) |
| CN (1) | CN100575355C (enExample) |
| AT (1) | ATE490259T1 (enExample) |
| DE (1) | DE602005025140D1 (enExample) |
| SE (1) | SE0402199D0 (enExample) |
| WO (1) | WO2006031180A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103755605B (zh) * | 2013-12-30 | 2016-08-17 | 中国科学院上海硅酸盐研究所 | 对己硫基苯甲醛的制备方法 |
| CN103980306B (zh) * | 2014-04-28 | 2017-02-15 | 湖南大学 | 一种以含p(o)‑oh类化合物制备次膦酸/亚膦酸/磷酸酯类化合物的方法 |
| TW201840578A (zh) * | 2017-02-22 | 2018-11-16 | 以色列商亞當阿甘公司 | 製備甲基膦酸丁基酯的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8721442D0 (en) * | 1987-09-11 | 1987-10-21 | Ciba Geigy Ag | Process |
| GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
| US20040167330A1 (en) | 2001-07-17 | 2004-08-26 | Ivan Lukes | Novel chelating agents and conjugates thereof, their synthesis and use as diagnois and therapeutic agents |
| ATE422891T1 (de) * | 2004-06-25 | 2009-03-15 | Univ Sydney | Neurologisch aktive verbindungen |
-
2004
- 2004-09-13 SE SE0402199A patent/SE0402199D0/xx unknown
-
2005
- 2005-09-12 EP EP05779058A patent/EP1791851B1/en not_active Expired - Lifetime
- 2005-09-12 CN CN200580030435A patent/CN100575355C/zh not_active Expired - Fee Related
- 2005-09-12 WO PCT/SE2005/001316 patent/WO2006031180A1/en not_active Ceased
- 2005-09-12 DE DE602005025140T patent/DE602005025140D1/de not_active Expired - Lifetime
- 2005-09-12 US US11/575,082 patent/US7557234B2/en not_active Expired - Fee Related
- 2005-09-12 AT AT05779058T patent/ATE490259T1/de not_active IP Right Cessation
- 2005-09-12 JP JP2007531131A patent/JP2008512451A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022043078A5 (enExample) | ||
| JP6373908B2 (ja) | キャプチャータグを用いた、三リン酸化オリゴヌクレオチドの精製 | |
| JP2010532365A5 (enExample) | ||
| JP2012521377A5 (enExample) | ||
| JP2008511601A5 (enExample) | ||
| RU2015118572A (ru) | Получение и составление композиции, содержащей ингибитор мек | |
| JP2008505157A5 (enExample) | ||
| CN112088155A (zh) | 用于制备2-[[5-(3-氯苯基)-3-羟基吡啶-2-羰基]氨基]乙酸的方法 | |
| CN104379591A (zh) | 用于制备2-脱氧-2-氟-2-甲基-d-呋喃核糖基核苷化合物的方法 | |
| JP2007523213A (ja) | 医薬的に許容できるデュロキセチンの塩及びその中間体の調製方法 | |
| JP2003306481A5 (enExample) | ||
| NO20070865L (no) | Fremgangsmate for fremstilling av 2'-deoksy-2',2'-difluorcytidin. | |
| JP2020519680A (ja) | ４−メトキシピロール誘導体の中間体の製造方法 | |
| RU2013137751A (ru) | Способ получения гиразы и ингибиторов топоизомеразы | |
| JPWO2021226269A5 (enExample) | ||
| JP2012532894A5 (enExample) | ||
| JP2008512451A5 (enExample) | ||
| JP2010540488A5 (enExample) | ||
| CA2671816A1 (en) | Salts of imidazole-5-carboxylic acid derivatives, a method for preparing same and pharmaceutical compositions comprising same | |
| JP2007522151A5 (enExample) | ||
| CA2554070A1 (en) | Macrolides with antiinflammatory activity | |
| CN103755574A (zh) | 一种具有多光子吸收性质的三（9,9-二烷基-9h-芴基）胺的合成方法 | |
| JP5009736B2 (ja) | 環状アミノエーテルを用いたマンニッヒ反応 | |
| RU2008136365A (ru) | Способ получения о-метил-n-нитроизомочевины | |
| JP2017523216A (ja) | ダプソン及びその中間体を合成する方法 |