JP2008510701A5 - - Google Patents
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- Publication number
- JP2008510701A5 JP2008510701A5 JP2007527975A JP2007527975A JP2008510701A5 JP 2008510701 A5 JP2008510701 A5 JP 2008510701A5 JP 2007527975 A JP2007527975 A JP 2007527975A JP 2007527975 A JP2007527975 A JP 2007527975A JP 2008510701 A5 JP2008510701 A5 JP 2008510701A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxyphenyl
- chlorophenyl
- methylphenyl
- phenyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Claims (6)
- Rが4−メトキシフェニルである、請求項1に記載の化合物。
- Rが4−メトキシフェニルである、請求項3に記載する組成物。
- Rが4−メトキシフェニルである、請求項5に記載する医薬品組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60273604P | 2004-08-19 | 2004-08-19 | |
US60/602,736 | 2004-08-19 | ||
PCT/US2005/029259 WO2006023562A2 (en) | 2004-08-19 | 2005-08-17 | 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2, 4-dione and analogues as inhibitors of macrophage elastase |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2008510701A JP2008510701A (ja) | 2008-04-10 |
JP2008510701A5 true JP2008510701A5 (ja) | 2008-10-02 |
JP5042833B2 JP5042833B2 (ja) | 2012-10-03 |
Family
ID=35968136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007527975A Expired - Fee Related JP5042833B2 (ja) | 2004-08-19 | 2005-08-17 | マクロファージエラスターゼの阻害剤としての5−[3−(4−ベンジルオキシフェニルチオ)−フラ−2−イル]−イミダゾリジン−2,4−ジオン及び類似体 |
Country Status (17)
Country | Link |
---|---|
US (1) | US7179831B2 (ja) |
EP (1) | EP1789036B1 (ja) |
JP (1) | JP5042833B2 (ja) |
KR (1) | KR101197325B1 (ja) |
CN (1) | CN101014338B (ja) |
AT (1) | ATE508744T1 (ja) |
AU (1) | AU2005277432B2 (ja) |
BR (1) | BRPI0514470B8 (ja) |
CA (1) | CA2577430C (ja) |
DK (1) | DK1789036T3 (ja) |
ES (1) | ES2364068T3 (ja) |
HK (1) | HK1107774A1 (ja) |
MX (1) | MX2007001940A (ja) |
NZ (1) | NZ553258A (ja) |
RU (1) | RU2391339C2 (ja) |
SI (1) | SI1789036T1 (ja) |
WO (1) | WO2006023562A2 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008051260A1 (en) * | 2006-01-13 | 2008-05-02 | Battelle Memorial Institute | Methods for assessing copd-retlated diseases |
EP2907512A1 (en) | 2014-02-14 | 2015-08-19 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Inhibitors of MMP-12 as antiviral Agents |
US10532102B2 (en) | 2016-08-19 | 2020-01-14 | Foresee Pharmaceuticals Co., Ltd. | Pharmaceutical composition and methods of uses |
KR102199295B1 (ko) * | 2016-08-19 | 2021-01-07 | 포시 파마슈티컬스 컴퍼니 리미티드 | 약학적 조성물 및 사용 방법 |
EP3517531B1 (en) * | 2016-09-23 | 2021-02-24 | Kaken Pharmaceutical Co., Ltd. | Method for producing (r)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2h)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same |
PT3793995T (pt) | 2018-05-15 | 2024-05-02 | Foresee Pharmaceuticals Usa Inc | Inibidores de metaloproteinases de matriz (mmp) e métodos de uso dos mesmos |
WO2021097190A1 (en) * | 2019-11-14 | 2021-05-20 | Foresee Pharmaceuticals Co., Ltd. | Matrix metalloproteinase (mmp) inhibitors and methods of use thereof |
JP2024520819A (ja) * | 2021-06-08 | 2024-05-24 | フォアシー ファーマシューティカルズ カンパニー リミテッド | Mmp-12阻害薬の安全な投与 |
RU2766551C1 (ru) * | 2021-07-19 | 2022-03-15 | Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ) | 5-(4-хлорфенил)-3-((4-хлорфенил)амино)-5-(фенилтио)фуран-2(5н)-он, обладающий противомикробной активностью |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6352976B1 (en) | 1998-12-31 | 2002-03-05 | Aventis Pharmaceuticals Inc. | Selective inhibitors of MMP-12 |
WO2000040577A1 (en) | 1998-12-31 | 2000-07-13 | Aventis Pharmaceuticals Inc. | 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12 |
EP1288199A4 (en) | 2000-04-28 | 2005-10-12 | Shionogi & Co | INHIBITORS OF MMP-12 |
SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
JP2004535411A (ja) | 2001-05-25 | 2004-11-25 | ブリストルーマイヤーズ スクイブ カンパニー | マトリックスメタロプロテナーゼ及び/またはTNF−α転換酵素(TACE)の阻害剤としてのヒダントイン及び関連複素環化合物 |
EP1394159A1 (fr) | 2002-08-13 | 2004-03-03 | Warner-Lambert Company LLC | Nouveaux dérivés de thiophène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
GB0219896D0 (en) | 2002-08-27 | 2002-10-02 | Bayer Ag | Dihydropyridine derivatives |
SE0202539D0 (sv) | 2002-08-27 | 2002-08-27 | Astrazeneca Ab | Compounds |
EP1546109A4 (en) * | 2002-10-04 | 2005-11-09 | Bristol Myers Squibb Co | HYDANTOIN DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND / OR TNF-ALPHA CONVERSION ENZYME (TACE) |
-
2005
- 2005-08-17 CA CA2577430A patent/CA2577430C/en not_active Expired - Fee Related
- 2005-08-17 AT AT05786673T patent/ATE508744T1/de not_active IP Right Cessation
- 2005-08-17 RU RU2007105822/04A patent/RU2391339C2/ru not_active IP Right Cessation
- 2005-08-17 SI SI200531283T patent/SI1789036T1/sl unknown
- 2005-08-17 CN CN2005800285556A patent/CN101014338B/zh not_active Expired - Fee Related
- 2005-08-17 AU AU2005277432A patent/AU2005277432B2/en not_active Ceased
- 2005-08-17 JP JP2007527975A patent/JP5042833B2/ja not_active Expired - Fee Related
- 2005-08-17 EP EP05786673A patent/EP1789036B1/en not_active Not-in-force
- 2005-08-17 US US11/205,954 patent/US7179831B2/en active Active
- 2005-08-17 KR KR1020077006294A patent/KR101197325B1/ko active IP Right Grant
- 2005-08-17 WO PCT/US2005/029259 patent/WO2006023562A2/en active Application Filing
- 2005-08-17 ES ES05786673T patent/ES2364068T3/es active Active
- 2005-08-17 DK DK05786673.3T patent/DK1789036T3/da active
- 2005-08-17 MX MX2007001940A patent/MX2007001940A/es active IP Right Grant
- 2005-08-17 NZ NZ553258A patent/NZ553258A/en not_active IP Right Cessation
- 2005-08-17 BR BRPI0514470A patent/BRPI0514470B8/pt not_active IP Right Cessation
-
2008
- 2008-02-11 HK HK08101512.9A patent/HK1107774A1/xx not_active IP Right Cessation
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