JP2008509950A5 - - Google Patents
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- Publication number
- JP2008509950A5 JP2008509950A5 JP2007526351A JP2007526351A JP2008509950A5 JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5 JP 2007526351 A JP2007526351 A JP 2007526351A JP 2007526351 A JP2007526351 A JP 2007526351A JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- dioxo
- imidazolidin
- thiazol
- butyramide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60217504P | 2004-08-17 | 2004-08-17 | |
| US60/602,175 | 2004-08-17 | ||
| US68299705P | 2005-05-20 | 2005-05-20 | |
| US60/682,997 | 2005-05-20 | ||
| PCT/EP2005/008633 WO2006018188A2 (en) | 2004-08-17 | 2005-08-09 | Substituted hydantoins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008509950A JP2008509950A (ja) | 2008-04-03 |
| JP2008509950A5 true JP2008509950A5 (https=) | 2012-01-05 |
| JP4927733B2 JP4927733B2 (ja) | 2012-05-09 |
Family
ID=35589619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007526351A Expired - Fee Related JP4927733B2 (ja) | 2004-08-17 | 2005-08-09 | 置換ヒダントイン |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7427635B2 (https=) |
| EP (1) | EP1781649B1 (https=) |
| JP (1) | JP4927733B2 (https=) |
| KR (2) | KR20090006885A (https=) |
| AR (1) | AR050297A1 (https=) |
| AT (1) | ATE404556T1 (https=) |
| AU (1) | AU2005274390B2 (https=) |
| BR (1) | BRPI0514515A (https=) |
| CA (1) | CA2576599A1 (https=) |
| DE (1) | DE602005008986D1 (https=) |
| ES (1) | ES2313389T3 (https=) |
| MX (1) | MX2007001846A (https=) |
| PL (1) | PL1781649T3 (https=) |
| RU (1) | RU2383542C2 (https=) |
| TW (1) | TW200621764A (https=) |
| WO (1) | WO2006018188A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200621766A (en) * | 2004-09-17 | 2006-07-01 | Hoffmann La Roche | Substituted hydantoins |
| US7612212B2 (en) * | 2006-02-22 | 2009-11-03 | Hoffmann-La Roche Inc. | Substituted hydantoins |
| JP2010526848A (ja) * | 2007-05-11 | 2010-08-05 | エフ．ホフマン−ラ ロシュ アーゲー | 難溶性薬物用の医薬組成物 |
| ATE551336T1 (de) | 2007-08-16 | 2012-04-15 | Hoffmann La Roche | Substituierte hydantoine |
| JP2011506533A (ja) | 2007-12-20 | 2011-03-03 | エフ．ホフマン−ラ ロシュ アーゲー | Ｍｅｋキナーゼ阻害剤としての置換ヒダントイン |
| MX2010014066A (es) * | 2008-06-16 | 2011-06-01 | Univ Tennessee Res Foundation | Compuestos para el tratamiento del cancer. |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| US8822513B2 (en) | 2010-03-01 | 2014-09-02 | Gtx, Inc. | Compounds for treatment of cancer |
| WO2010068738A1 (en) | 2008-12-10 | 2010-06-17 | Dana-Farber Cancer Institute, Inc. | Mek mutations conferring resistance to mek inhibitors |
| TW201113280A (en) * | 2009-07-03 | 2011-04-16 | Nensius Res As | Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the CNS |
| ES2576061T3 (es) | 2010-02-25 | 2016-07-05 | Dana-Farber Cancer Institute, Inc. | Mutaciones de BRAF que confieren resistencia a inhibidores de BRAF |
| JP5879273B2 (ja) | 2010-03-01 | 2016-03-08 | ジーティーエックス・インコーポレイテッド | 癌を処置するための化合物 |
| BR112012022801B8 (pt) | 2010-03-09 | 2019-10-29 | Dana Farber Cancer Inst Inc | método de identificar um indivíduo que tem câncer que é provável beneficiar-se do tratamento com uma terapia de combinação com um inibidor de raf e um segundo inibidor e uso de um inibidor de raf e um segundo inibidor para a fabricação de um medicamento para tratar câncer |
| JP5960683B2 (ja) | 2010-04-28 | 2016-08-02 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 殺真菌剤としてのケトヘテロアリールピペリジンおよび−ピペラジン誘導体 |
| US20150141470A1 (en) | 2012-05-08 | 2015-05-21 | The Broad Institute, Inc. | Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy |
| JP7235859B2 (ja) * | 2018-09-17 | 2023-03-08 | ユンジン ファーム．カンパニー、リミテッド | 新規なチアゾール誘導体及びその薬学的に許容される塩 |
| EP4119556A1 (en) * | 2020-03-13 | 2023-01-18 | Yungjin Pharm. Co., Ltd. | Pharmaceutical composition for preventing or treating cancer comprising azole derivatives or pharmaceutically acceptable salt thereof |
| WO2021182914A1 (ko) * | 2020-03-13 | 2021-09-16 | 영진약품 주식회사 | 신규한 cdk7 억제 화합물 및 이의 약제학적으로 허용가능한 염 |
| KR20210146144A (ko) | 2020-05-26 | 2021-12-03 | 엘지전자 주식회사 | 카트부 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770573A (en) * | 1993-12-06 | 1998-06-23 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
| NZ501276A (en) | 1997-07-01 | 2000-10-27 | Warner Lambert Co | 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders |
| AU5227001A (en) * | 2000-05-03 | 2001-11-12 | Hoffmann La Roche | Hydantoin-containing glucokinase activators |
| JP2004534857A (ja) * | 2001-07-19 | 2004-11-18 | フアルマシア・イタリア・エツセ・ピー・アー | フェニルアセトアミド−チアゾール誘導体、それらの製造のための方法及び抗癌剤としてのそれらの使用 |
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2005
- 2005-08-09 BR BRPI0514515-5A patent/BRPI0514515A/pt not_active IP Right Cessation
- 2005-08-09 KR KR1020087032084A patent/KR20090006885A/ko not_active Ceased
- 2005-08-09 PL PL05771890T patent/PL1781649T3/pl unknown
- 2005-08-09 CA CA002576599A patent/CA2576599A1/en not_active Abandoned
- 2005-08-09 AT AT05771890T patent/ATE404556T1/de active
- 2005-08-09 EP EP05771890A patent/EP1781649B1/en not_active Expired - Lifetime
- 2005-08-09 DE DE602005008986T patent/DE602005008986D1/de not_active Expired - Lifetime
- 2005-08-09 RU RU2007109651/04A patent/RU2383542C2/ru not_active IP Right Cessation
- 2005-08-09 JP JP2007526351A patent/JP4927733B2/ja not_active Expired - Fee Related
- 2005-08-09 KR KR1020077004075A patent/KR100889721B1/ko not_active Expired - Fee Related
- 2005-08-09 MX MX2007001846A patent/MX2007001846A/es active IP Right Grant
- 2005-08-09 AU AU2005274390A patent/AU2005274390B2/en not_active Ceased
- 2005-08-09 WO PCT/EP2005/008633 patent/WO2006018188A2/en not_active Ceased
- 2005-08-09 ES ES05771890T patent/ES2313389T3/es not_active Expired - Lifetime
- 2005-08-11 US US11/202,299 patent/US7427635B2/en not_active Expired - Fee Related
- 2005-08-15 TW TW094127672A patent/TW200621764A/zh unknown
- 2005-08-16 AR ARP050103440A patent/AR050297A1/es unknown