JP2008509950A5 - - Google Patents

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Publication number
JP2008509950A5
JP2008509950A5 JP2007526351A JP2007526351A JP2008509950A5 JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5 JP 2007526351 A JP2007526351 A JP 2007526351A JP 2007526351 A JP2007526351 A JP 2007526351A JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5
Authority
JP
Japan
Prior art keywords
phenyl
dioxo
imidazolidin
thiazol
butyramide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007526351A
Other languages
English (en)
Japanese (ja)
Other versions
JP4927733B2 (ja
JP2008509950A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2005/008633 external-priority patent/WO2006018188A2/en
Publication of JP2008509950A publication Critical patent/JP2008509950A/ja
Publication of JP2008509950A5 publication Critical patent/JP2008509950A5/ja
Application granted granted Critical
Publication of JP4927733B2 publication Critical patent/JP4927733B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007526351A 2004-08-17 2005-08-09 置換ヒダントイン Expired - Fee Related JP4927733B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60217504P 2004-08-17 2004-08-17
US60/602,175 2004-08-17
US68299705P 2005-05-20 2005-05-20
US60/682,997 2005-05-20
PCT/EP2005/008633 WO2006018188A2 (en) 2004-08-17 2005-08-09 Substituted hydantoins

Publications (3)

Publication Number Publication Date
JP2008509950A JP2008509950A (ja) 2008-04-03
JP2008509950A5 true JP2008509950A5 (https=) 2012-01-05
JP4927733B2 JP4927733B2 (ja) 2012-05-09

Family

ID=35589619

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007526351A Expired - Fee Related JP4927733B2 (ja) 2004-08-17 2005-08-09 置換ヒダントイン

Country Status (16)

Country Link
US (1) US7427635B2 (https=)
EP (1) EP1781649B1 (https=)
JP (1) JP4927733B2 (https=)
KR (2) KR20090006885A (https=)
AR (1) AR050297A1 (https=)
AT (1) ATE404556T1 (https=)
AU (1) AU2005274390B2 (https=)
BR (1) BRPI0514515A (https=)
CA (1) CA2576599A1 (https=)
DE (1) DE602005008986D1 (https=)
ES (1) ES2313389T3 (https=)
MX (1) MX2007001846A (https=)
PL (1) PL1781649T3 (https=)
RU (1) RU2383542C2 (https=)
TW (1) TW200621764A (https=)
WO (1) WO2006018188A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200621766A (en) * 2004-09-17 2006-07-01 Hoffmann La Roche Substituted hydantoins
US7612212B2 (en) 2006-02-22 2009-11-03 Hoffmann-La Roche Inc. Substituted hydantoins
CN101702878B (zh) * 2007-05-11 2012-11-28 弗·哈夫曼-拉罗切有限公司 可溶性差的药物的药物组合物
MX2010001581A (es) 2007-08-16 2010-03-15 Hoffmann La Roche Hidantoinas substituidas.
US8063085B2 (en) 2007-12-20 2011-11-22 Hoffmann-La Roche Inc. Substituted hydantoins
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
AU2009330686B2 (en) * 2008-06-16 2014-07-03 The Ohio State University Research Foundation Compounds for the treatment of cancer
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
EP2370568B1 (en) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
WO2011000945A2 (en) * 2009-07-03 2011-01-06 Nensius Research A/S Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns
EP3028699B1 (en) 2010-02-25 2018-03-21 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
MX2012010115A (es) 2010-03-01 2013-02-26 Gtx Inc Compuestos para el tratamiento de cancer.
CN103038364A (zh) 2010-03-09 2013-04-10 达纳-法伯癌症研究所公司 诊断和治疗具有或发展对于第一种癌症治疗的抗性的患者中的癌症的方法
BR112012027762B1 (pt) 2010-04-28 2018-06-05 Bayer Intellectual Property Gmbh Derivados de cetoheteroarilpiperidina e - piperazina como fungicidas
US20150141470A1 (en) 2012-05-08 2015-05-21 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy
US12110299B2 (en) * 2018-09-17 2024-10-08 Yungjin Pharm. Co., Ltd. Thiazole derivatives and pharmaceutically acceptable salts thereof
WO2021182914A1 (ko) * 2020-03-13 2021-09-16 영진약품 주식회사 신규한 cdk7 억제 화합물 및 이의 약제학적으로 허용가능한 염
US20230095520A1 (en) * 2020-03-13 2023-03-30 Yungjin Pharm. Co., Ltd. Pharmaceutical composition for preventing or treating cancer comprising azole derivatives or pharmaceutically acceptable salt thereof
KR20210146144A (ko) 2020-05-26 2021-12-03 엘지전자 주식회사 카트부

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770573A (en) * 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
NZ501276A (en) 1997-07-01 2000-10-27 Warner Lambert Co 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders
AU2001252270B2 (en) * 2000-05-03 2005-12-15 F. Hoffmann-La Roche Ag Hydantoin-containing glucokinase activators
ATE345341T1 (de) * 2001-07-19 2006-12-15 Pfizer Italia Srl Phenylacetamido-thiazole verbindungen, verfahren zu ihren herstellung und ihre anwendung als antitumor mittel

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