JP2008509950A5 - - Google Patents
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- Publication number
- JP2008509950A5 JP2008509950A5 JP2007526351A JP2007526351A JP2008509950A5 JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5 JP 2007526351 A JP2007526351 A JP 2007526351A JP 2007526351 A JP2007526351 A JP 2007526351A JP 2008509950 A5 JP2008509950 A5 JP 2008509950A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- dioxo
- imidazolidin
- thiazol
- butyramide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60217504P | 2004-08-17 | 2004-08-17 | |
| US60/602,175 | 2004-08-17 | ||
| US68299705P | 2005-05-20 | 2005-05-20 | |
| US60/682,997 | 2005-05-20 | ||
| PCT/EP2005/008633 WO2006018188A2 (en) | 2004-08-17 | 2005-08-09 | Substituted hydantoins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008509950A JP2008509950A (ja) | 2008-04-03 |
| JP2008509950A5 true JP2008509950A5 (enExample) | 2012-01-05 |
| JP4927733B2 JP4927733B2 (ja) | 2012-05-09 |
Family
ID=35589619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007526351A Expired - Fee Related JP4927733B2 (ja) | 2004-08-17 | 2005-08-09 | 置換ヒダントイン |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7427635B2 (enExample) |
| EP (1) | EP1781649B1 (enExample) |
| JP (1) | JP4927733B2 (enExample) |
| KR (2) | KR20090006885A (enExample) |
| AR (1) | AR050297A1 (enExample) |
| AT (1) | ATE404556T1 (enExample) |
| AU (1) | AU2005274390B2 (enExample) |
| BR (1) | BRPI0514515A (enExample) |
| CA (1) | CA2576599A1 (enExample) |
| DE (1) | DE602005008986D1 (enExample) |
| ES (1) | ES2313389T3 (enExample) |
| MX (1) | MX2007001846A (enExample) |
| PL (1) | PL1781649T3 (enExample) |
| RU (1) | RU2383542C2 (enExample) |
| TW (1) | TW200621764A (enExample) |
| WO (1) | WO2006018188A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200621766A (en) * | 2004-09-17 | 2006-07-01 | Hoffmann La Roche | Substituted hydantoins |
| US7612212B2 (en) * | 2006-02-22 | 2009-11-03 | Hoffmann-La Roche Inc. | Substituted hydantoins |
| WO2008138755A2 (en) * | 2007-05-11 | 2008-11-20 | F. Hoffmann-La Roche Ag | Pharmaceutical compositions for poorly soluble drugs |
| CN101778839A (zh) | 2007-08-16 | 2010-07-14 | 霍夫曼-拉罗奇有限公司 | 取代的乙内酰脲 |
| WO2009080523A1 (en) | 2007-12-20 | 2009-07-02 | F. Hoffmann-La Roche Ag | Substituted hydantoins as mek kinase inhibitors |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| US8822513B2 (en) | 2010-03-01 | 2014-09-02 | Gtx, Inc. | Compounds for treatment of cancer |
| DK2303021T3 (en) * | 2008-06-16 | 2019-04-08 | Univ Tennessee Res Found | RELATIONSHIPS FOR TREATING CANCER |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| EP2370568B1 (en) | 2008-12-10 | 2017-07-19 | Dana-Farber Cancer Institute, Inc. | Mek mutations conferring resistance to mek inhibitors |
| TW201113280A (en) * | 2009-07-03 | 2011-04-16 | Nensius Res As | Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the CNS |
| EP3028699B1 (en) | 2010-02-25 | 2018-03-21 | Dana-Farber Cancer Institute, Inc. | Braf mutations conferring resistance to braf inhibitors |
| KR101939704B1 (ko) | 2010-03-01 | 2019-01-17 | 지티엑스, 인코포레이티드 | 암 치료용 화합물 |
| EP2545187B1 (en) | 2010-03-09 | 2018-09-05 | Dana-Farber Cancer Institute, Inc. | Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy |
| MX2012012460A (es) | 2010-04-28 | 2012-11-21 | Bayer Cropscience Ag | Derivados de cetoheteroarilpiperidina y de cetoheteroarilpiperazin a como fungicidas. |
| WO2013169858A1 (en) | 2012-05-08 | 2013-11-14 | The Broad Institute, Inc. | Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy |
| EP3853225B1 (en) * | 2018-09-17 | 2023-11-29 | Yungjin Pharm. Co., Ltd. | N-(5-(3-(1-((thiazol-2-yl)amino)-1-oxopropan-2-yl)phenyl)pyridin-2-yl)acrylamide derivatives as cdk7 inhibitors for the treatment of cancer |
| KR20210116325A (ko) * | 2020-03-13 | 2021-09-27 | 영진약품 주식회사 | 티아졸 유도체 또는 이의 약제학적으로 허용가능한 염을 포함하는 암의 예방 또는 치료용 약학 조성물 |
| KR102335637B1 (ko) * | 2020-03-13 | 2021-12-06 | 영진약품 주식회사 | 신규한 cdk7 억제 화합물 및 이의 약제학적으로 허용가능한 염 |
| KR20210146144A (ko) | 2020-05-26 | 2021-12-03 | 엘지전자 주식회사 | 카트부 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770573A (en) * | 1993-12-06 | 1998-06-23 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
| AU757046B2 (en) | 1997-07-01 | 2003-01-30 | Warner-Lambert Company | 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors |
| AU5227001A (en) * | 2000-05-03 | 2001-11-12 | Hoffmann La Roche | Hydantoin-containing glucokinase activators |
| WO2003008365A2 (en) * | 2001-07-19 | 2003-01-30 | Pharmacia Italia S.P.A. | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents |
-
2005
- 2005-08-09 BR BRPI0514515-5A patent/BRPI0514515A/pt not_active IP Right Cessation
- 2005-08-09 ES ES05771890T patent/ES2313389T3/es not_active Expired - Lifetime
- 2005-08-09 RU RU2007109651/04A patent/RU2383542C2/ru not_active IP Right Cessation
- 2005-08-09 KR KR1020087032084A patent/KR20090006885A/ko not_active Ceased
- 2005-08-09 AU AU2005274390A patent/AU2005274390B2/en not_active Ceased
- 2005-08-09 EP EP05771890A patent/EP1781649B1/en not_active Expired - Lifetime
- 2005-08-09 CA CA002576599A patent/CA2576599A1/en not_active Abandoned
- 2005-08-09 MX MX2007001846A patent/MX2007001846A/es active IP Right Grant
- 2005-08-09 PL PL05771890T patent/PL1781649T3/pl unknown
- 2005-08-09 DE DE602005008986T patent/DE602005008986D1/de not_active Expired - Lifetime
- 2005-08-09 JP JP2007526351A patent/JP4927733B2/ja not_active Expired - Fee Related
- 2005-08-09 KR KR1020077004075A patent/KR100889721B1/ko not_active Expired - Fee Related
- 2005-08-09 AT AT05771890T patent/ATE404556T1/de active
- 2005-08-09 WO PCT/EP2005/008633 patent/WO2006018188A2/en not_active Ceased
- 2005-08-11 US US11/202,299 patent/US7427635B2/en not_active Expired - Fee Related
- 2005-08-15 TW TW094127672A patent/TW200621764A/zh unknown
- 2005-08-16 AR ARP050103440A patent/AR050297A1/es unknown
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