|
SI2384753T1
(sl)
*
|
2003-08-29 |
2016-06-30 |
The Brigham And Women's Hospital, Inc. |
Hidantoinski derivati kot inhibitorji celične nekroze
|
|
SE0302573D0
(sv)
|
2003-09-26 |
2003-09-26 |
Astrazeneca Ab |
Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
|
|
DE10354060A1
(de)
*
|
2003-11-19 |
2005-06-02 |
Merck Patent Gmbh |
Pyrrolderivate
|
|
US7880001B2
(en)
|
2004-04-29 |
2011-02-01 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
|
US20100222316A1
(en)
|
2004-04-29 |
2010-09-02 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US8415354B2
(en)
|
2004-04-29 |
2013-04-09 |
Abbott Laboratories |
Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
SG155188A1
(en)
*
|
2004-07-30 |
2009-09-30 |
Exelixis Inc |
Pyrrole derivatives as pharmaceutical agents
|
|
MX2007003105A
(es)
|
2004-09-24 |
2007-06-07 |
Aztrazeneca Ab |
Derivados de bencimidazol, composiciones que los contienen, sus preparaciones y sus usos i.
|
|
JP5133702B2
(ja)
|
2005-01-05 |
2013-01-30 |
アボット・ラボラトリーズ |
11−β−ヒドロキシステロイドデヒドロゲナーゼ1型酵素の阻害薬
|
|
WO2006074244A2
(en)
|
2005-01-05 |
2006-07-13 |
Abbott Laboratories |
Adamantyl derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US20090192198A1
(en)
|
2005-01-05 |
2009-07-30 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
US8198331B2
(en)
|
2005-01-05 |
2012-06-12 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
WO2006076202A1
(en)
*
|
2005-01-10 |
2006-07-20 |
Exelixis, Inc. |
Heterocyclic carboxamide compounds as steroid nuclear receptors ligands
|
|
TW200745049A
(en)
|
2006-03-23 |
2007-12-16 |
Astrazeneca Ab |
New crystalline forms
|
|
TW200808769A
(en)
|
2006-04-18 |
2008-02-16 |
Astrazeneca Ab |
Therapeutic compounds
|
|
SI2089367T1
(sl)
|
2006-10-31 |
2012-02-29 |
Pfizer Prod Inc |
Spojine pirazolina kot antagonisti mineralokortikoidnih receptorjev
|
|
CN101679243B
(zh)
*
|
2007-04-09 |
2012-09-26 |
第一三共株式会社 |
吡咯衍生物的阻转异构体
|
|
US20090099242A1
(en)
*
|
2007-08-15 |
2009-04-16 |
Cuny Gregory D |
Heterocyclic inhibitors of necroptosis
|
|
JP5736098B2
(ja)
|
2007-08-21 |
2015-06-17 |
アッヴィ・インコーポレイテッド |
中枢神経系障害を治療するための医薬組成物
|
|
EP2185506A1
(en)
*
|
2007-08-22 |
2010-05-19 |
Allergan, Inc. |
Pyrrole compounds having sphingosine-1-phosphate receptor agonist or antagonist biological activity
|
|
JP5411141B2
(ja)
|
2007-09-10 |
2014-02-12 |
カルシメディカ,インク. |
細胞内カルシウムを調節する化合物
|
|
US8389567B2
(en)
*
|
2007-12-12 |
2013-03-05 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
CA2720164A1
(en)
*
|
2008-03-31 |
2009-10-08 |
Teva Pharmaceutical Industries Ltd. |
Processes for preparing sunitinib and salts thereof
|
|
GB0808282D0
(en)
*
|
2008-05-07 |
2008-06-11 |
Medical Res Council |
Compounds for use in stabilizing p53 mutants
|
|
WO2010019910A1
(en)
|
2008-08-15 |
2010-02-18 |
N30 Pharmaceuticals, Llc |
Novel pyrrole inhibitors of s-nitrosoglutathione reductase as therapeutic agents
|
|
DK2315590T3
(da)
|
2008-08-15 |
2012-11-19 |
N30 Pharmaceuticals Inc |
Pyrrolinhibitorer af S-nitrosoglutathionreduktase
|
|
DK2318007T3
(da)
|
2008-08-15 |
2013-03-25 |
N30 Pharmaceuticals Inc |
Nye pyrrol-inhibitorer af s-nitrosoglutathion-reduktase som terapeutiske midler
|
|
US7906553B2
(en)
|
2008-08-27 |
2011-03-15 |
Calcimedica, Inc. |
Substituted thiophene modulators of intracellular calcium
|
|
US8524763B2
(en)
|
2008-09-22 |
2013-09-03 |
Calcimedica, Inc. |
Inhibitors of store operated calcium release
|
|
CN102177137B
(zh)
*
|
2008-10-08 |
2015-03-18 |
埃克塞利希斯股份有限公司 |
1-苯基吡咯化合物
|
|
AU2009302371B2
(en)
|
2008-10-08 |
2015-02-12 |
Exelixis, Inc. |
Atropisomers of (hydroxyalkyl) pyrrole derivatives
|
|
CA2772760A1
(en)
|
2008-12-23 |
2010-07-01 |
President And Fellows Of Harvard College |
Small molecule inhibitors of necroptosis
|
|
WO2010107476A1
(en)
*
|
2009-03-19 |
2010-09-23 |
Duke University |
Inhibiting gsnor
|
|
WO2010129208A1
(en)
*
|
2009-05-05 |
2010-11-11 |
Merck Sharp & Dohme Corp. |
P38 kinase inhibiting agents
|
|
EP2253617A1
(de)
*
|
2009-05-20 |
2010-11-24 |
Bayer CropScience AG |
Halogen-substituierte Verbindungen als Pestizide
|
|
WO2011025706A2
(en)
|
2009-08-26 |
2011-03-03 |
Schering Corporation |
Heterocyclic amide compounds as protein kinase inhibitors
|
|
WO2011034962A2
(en)
*
|
2009-09-16 |
2011-03-24 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
|
TWI532725B
(zh)
*
|
2010-01-26 |
2016-05-11 |
賽諾菲阿凡提斯公司 |
經氧取代之3-雜芳醯基胺基-丙酸衍生物及其作為藥物之用途
|
|
EP2977084B1
(en)
|
2010-05-10 |
2017-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
|
|
JP6180930B2
(ja)
|
2010-06-16 |
2017-08-16 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
創傷治癒過程における再上皮化を刺激するための方法及び組成物
|
|
EP2609095A4
(en)
|
2010-08-27 |
2014-06-18 |
Calcimedica Inc |
COMPOUNDS MODULATING INTRACELLULAR CALCIUM
|
|
US20140113898A1
(en)
*
|
2010-11-08 |
2014-04-24 |
Zalicus Pharmaceuticals Ltd. |
Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers
|
|
WO2013079223A1
(en)
|
2011-12-02 |
2013-06-06 |
Phenex Pharmaceuticals Ag |
Pyrrolo carboxamides as modulators of orphan nuclear receptor rar-related orphan receptor-gamma (rorϒ, nr1f3) activity and for the treatment of chronic inflammatory and autoimmune diseases
|
|
WO2013096744A1
(en)
|
2011-12-21 |
2013-06-27 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
|
EA038942B1
(ru)
|
2012-08-28 |
2021-11-12 |
Янссен Сайенсиз Айрлэнд Юси |
Сульфамоил-ариламиды и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
WO2014059333A1
(en)
|
2012-10-12 |
2014-04-17 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
HUE034820T2
(en)
|
2013-02-28 |
2018-02-28 |
Janssen Sciences Ireland Uc |
Sulphamoyl arylamides and their use as medicaments for the treatment of hepatitis B
|
|
US9725452B2
(en)
|
2013-03-15 |
2017-08-08 |
Presidents And Fellows Of Harvard College |
Substituted indoles and pyrroles as RIP kinase inhibitors
|
|
EA027068B1
(ru)
|
2013-04-03 |
2017-06-30 |
Янссен Сайенсиз Айрлэнд Юси |
Производные n-фенилкарбоксамида и их применение в качестве лекарственных препаратов для лечения гепатита b
|
|
CA2958625C
(en)
*
|
2013-04-10 |
2019-05-28 |
Daiichi Sankyo Company, Limited |
Crystal of pyrrole derivative and method for producing the same
|
|
EA035500B1
(ru)
|
2013-05-17 |
2020-06-25 |
Янссен Сайенсиз Айрлэнд Юси |
Производные сульфамоилтиофенамида и их применение в качестве медикаментов для лечения гепатита b
|
|
TWI651300B
(zh)
|
2013-05-17 |
2019-02-21 |
健生科學愛爾蘭無限公司 |
胺磺醯基吡咯醯胺衍生物及其作為用於治療b型肝炎藥物的用途
|
|
EP3025711B1
(en)
*
|
2013-07-23 |
2020-11-18 |
Daiichi Sankyo Company, Limited |
Medicine for preventing or treating hypertension
|
|
DK3024819T3
(en)
|
2013-07-25 |
2018-06-06 |
Janssen Sciences Ireland Uc |
GLYOXAMIDE-SUBSTITUTED PYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR TREATING HEPATITIS B
|
|
JP6422871B2
(ja)
*
|
2013-08-27 |
2018-11-14 |
第一三共株式会社 |
ピロール誘導体の製造方法及びその中間体
|
|
KR102290189B1
(ko)
|
2013-10-23 |
2021-08-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
카르복스아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
|
WO2015083130A1
(en)
*
|
2013-12-06 |
2015-06-11 |
Aurigene Discovery Technologies Limited |
Fused pyridine and pyrimidine derivatives as ror gamma modulators
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
JP6553059B2
(ja)
|
2014-02-05 |
2019-07-31 |
ノヴィラ・セラピューティクス・インコーポレイテッド |
Hbv感染の治療のための併用療法
|
|
WO2015118057A1
(en)
|
2014-02-06 |
2015-08-13 |
Janssen Sciences Ireland Uc |
Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
EP3229807A4
(en)
|
2014-12-11 |
2018-10-17 |
President and Fellows of Harvard College |
Inhibitors of cellular necrosis and related methods
|
|
CN107205984B
(zh)
*
|
2015-01-26 |
2019-11-12 |
第一三共株式会社 |
吡咯甲酰胺的固体组合物
|
|
WO2016172496A1
(en)
|
2015-04-23 |
2016-10-27 |
Constellation Pharmaceuticals, Inc. |
Lsd1 inhibitors and uses thereof
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
TWI623316B
(zh)
*
|
2015-12-22 |
2018-05-11 |
Taiho Pharmaceutical Co Ltd |
Antitumor effect enhancer derived from pyrrolopyrimidine compound
|
|
US10882841B2
(en)
|
2016-03-01 |
2021-01-05 |
University Of Maryland, Baltimore |
Wnt signaling pathway inhibitors for treatments of disease
|
|
CN108778334A
(zh)
|
2016-03-24 |
2018-11-09 |
第三共株式会社 |
用于治疗肾脏疾病的药物
|
|
SG10202011827YA
(en)
|
2016-04-15 |
2021-01-28 |
Novira Therapeutics Inc |
Combinations and methods comprising a capsid assembly inhibitor
|
|
US10918639B2
(en)
|
2016-10-11 |
2021-02-16 |
Bayer Pharma Aktiengesellschaft |
Combination containing SGC stimulators and mineralocorticoid receptor antagonists
|
|
CA3039735A1
(en)
|
2016-10-11 |
2018-04-19 |
Bayer Pharma Aktiengesellschaft |
Combination containing sgc activators and mineralocorticoid receptor antagonists
|
|
DK3532459T3
(da)
|
2016-10-26 |
2023-10-30 |
Constellation Pharmaceuticals Inc |
Lsd1-hæmmere og medicinske anvendelser deraf
|
|
WO2018153898A1
(de)
|
2017-02-22 |
2018-08-30 |
Bayer Pharma Aktiengesellschaft |
Selektive partielle adenosin a1 rezeptor-agonisten in kombination mit mineralocorticoid-rezeptor-antagonisten
|
|
DE102017008472A1
(de)
|
2017-09-08 |
2018-05-03 |
Bayer Pharma Aktiengesellschaft |
Kombination enthaltend PDE5 Inhibitoren und Mineralocorticoid-Rezeptor-Antagonisten
|
|
CA3090125A1
(en)
|
2018-03-14 |
2019-09-19 |
Janssen Sciences Ireland Unlimited Company |
Capsid assembly modulator dosing regimen
|
|
CN115974753A
(zh)
|
2018-03-30 |
2023-04-18 |
正大天晴药业集团股份有限公司 |
含有n杂五元环化合物和用途
|
|
EA202092159A1
(ru)
|
2019-01-25 |
2020-12-15 |
Чиа Тай Тянцин Фармасьютикал Груп Ко., Лтд. |
Содержащий n-гетероциклическое пятичленное кольцо ингибитор сборки капсидного белка, его фармацевтическая композиция и их применение
|
|
MX2021010145A
(es)
|
2019-02-22 |
2021-09-14 |
Janssen Sciences Ireland Unlimited Co |
Derivados de amida utiles en el tratamiento de una infeccion por vhb o de enfermedades inducidas por vhb.
|
|
MA55879A
(fr)
|
2019-05-06 |
2022-03-16 |
Janssen Sciences Ireland Unlimited Co |
Dérivés d'amide utiles dans le traitement d'une infection par le virus de l'hépatite b ou de maladies induites par le virus de l'hépatite b
|
|
WO2021058001A1
(zh)
|
2019-09-29 |
2021-04-01 |
正大天晴药业集团股份有限公司 |
N杂五元环化合物的晶型及其应用
|
|
ES3064043T3
(en)
|
2019-09-29 |
2026-04-22 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
Crystalline forms of a capsid protein assembly inhibitor containing a pyrrole ring, and application thereof
|
|
CN112707854B
(zh)
|
2019-10-25 |
2022-03-15 |
年衍药业(珠海)有限公司 |
吡咯酰胺类化合物及其用途
|
|
RU2738405C1
(ru)
*
|
2020-05-26 |
2020-12-11 |
Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" |
АМИД (Е)-2-АМИНО-4-ОКСО-5-(2-ОКСО-2-ФЕНИЛЭТИЛИДЕН)-1-(3-ЭТОКСИКАРБОНИЛ)-4,5,6-7-ТЕТРАГИДРОБЕНЗО[b]ТИОФЕН-2-ИЛ)4,5-ДИГИДРО-1Н-ПИРРОЛ-3-КАРБОНОВОЙ КИСЛОТЫ, ОБЛАДАЮЩИЙ ПРОТИВОМИКРОБНОЙ АКТИВНОСТЬЮ
|
|
CA3179059A1
(en)
*
|
2020-06-09 |
2021-12-16 |
Anima Biotech Inc. |
Collagen 1 translation inhibitors and methods of use thereof
|
|
CA3216002A1
(en)
|
2021-04-26 |
2022-11-03 |
Jiancheng Wang |
Preparation method for pyrrole amide compound
|
|
CN114456098B
(zh)
*
|
2022-01-19 |
2024-06-14 |
大连理工大学 |
糖尿病肾病药物艾莎利酮的制备方法
|