JP2008503712A5 - - Google Patents
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- JP2008503712A5 JP2008503712A5 JP2007515968A JP2007515968A JP2008503712A5 JP 2008503712 A5 JP2008503712 A5 JP 2008503712A5 JP 2007515968 A JP2007515968 A JP 2007515968A JP 2007515968 A JP2007515968 A JP 2007515968A JP 2008503712 A5 JP2008503712 A5 JP 2008503712A5
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- Prior art keywords
- acid sequence
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58156804P | 2004-06-21 | 2004-06-21 | |
| PCT/EP2005/052875 WO2005124342A2 (en) | 2004-06-21 | 2005-06-21 | Methods and means for treatment of osteoarthritis |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011171363A Division JP5595989B2 (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
| JP2011171061A Division JP2012021995A (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008503712A JP2008503712A (ja) | 2008-02-07 |
| JP2008503712A5 true JP2008503712A5 (enExample) | 2008-07-31 |
Family
ID=35510369
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515968A Pending JP2008503712A (ja) | 2004-06-21 | 2005-06-21 | 骨関節炎治療の方法及び手段 |
| JP2011171363A Expired - Fee Related JP5595989B2 (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
| JP2011171061A Pending JP2012021995A (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011171363A Expired - Fee Related JP5595989B2 (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
| JP2011171061A Pending JP2012021995A (ja) | 2004-06-21 | 2011-08-04 | 骨関節炎治療の方法及び手段 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20070004658A1 (enExample) |
| EP (3) | EP2360474B1 (enExample) |
| JP (3) | JP2008503712A (enExample) |
| ES (2) | ES2427136T3 (enExample) |
| WO (1) | WO2005124342A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008503712A (ja) * | 2004-06-21 | 2008-02-07 | ガラパゴス・ナムローゼ・フェンノートシャップ | 骨関節炎治療の方法及び手段 |
| US8673268B2 (en) | 2004-10-15 | 2014-03-18 | Galapagos N.V. | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| US7485468B2 (en) | 2004-10-15 | 2009-02-03 | Galapagos Bv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| ES2310469B1 (es) * | 2007-03-08 | 2009-11-16 | Consejo Superior Investig. Cientificas | Uso compuestos inhibidores actividad snail1 en elaboracion composiciones farmaceuticas utiles para tratamiento de condrodisplasias, procedimiento identificacion compuestos inhibidores, dichas composiciones farmaceuticas, procedimiento diagnostico condrodisplasias y aplicaciones. |
| WO2008112266A1 (en) * | 2007-03-12 | 2008-09-18 | Thomas Lally | Cartilage stimluaiting bio-material composition and method |
| WO2008155397A2 (en) | 2007-06-20 | 2008-12-24 | Galapagos N.V. | Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases |
| US8501449B2 (en) | 2007-12-04 | 2013-08-06 | Proteon Therapeutics, Inc. | Recombinant elastase proteins and methods of manufacturing and use thereof |
| JO3041B1 (ar) | 2008-07-25 | 2016-09-05 | Galapagos Nv | مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية |
| JO3030B1 (ar) | 2009-06-26 | 2016-09-05 | Galapagos Nv | مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات |
| TWI462920B (zh) | 2009-06-26 | 2014-12-01 | 葛萊伯格有限公司 | 用於治療退化性及發炎疾病之新穎化合物 |
| RU2405490C1 (ru) * | 2009-06-29 | 2010-12-10 | Анатолий Дмитриевич Олейник | Способ превентивного лечения рецидива болевого синдрома при хирургических вмешательствах на поясничных межпозвонковых дисках |
| WO2012127506A1 (en) | 2011-03-22 | 2012-09-27 | Advinus Therapeutics Limited | Substituted fused tricyclic compounds, compositions and medicinal applications thereof |
| AR086042A1 (es) | 2011-04-28 | 2013-11-13 | Galapagos Nv | Compuesto util para el tratamiento de enfermedades degenerativas e inflamatorias y composicion farmaceutica |
| JP2015529242A (ja) | 2012-09-21 | 2015-10-05 | アドヴィヌス セラピューティクス リミテッドAdvinus Therapeutics Limited | 置換された縮合三環式化合物、組成物およびその医薬用途 |
| KR101665301B1 (ko) | 2013-08-07 | 2016-10-11 | 카딜라 핼쓰캐어 리미티드 | 야누스 키나제의 억제제로서 n-시아노메틸아미드 |
| GB201401086D0 (en) | 2014-01-23 | 2014-03-12 | Galapagos Nv | Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
| GB201402071D0 (en) | 2014-02-07 | 2014-03-26 | Galapagos Nv | Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
| GB201402070D0 (en) | 2014-02-07 | 2014-03-26 | Galapagos Nv | Pharmaceutical compositions for the treatment of inflammatory disorders |
| KR101710127B1 (ko) | 2014-08-29 | 2017-02-27 | 한화제약주식회사 | 야누스인산화효소 억제제로서의 치환된 N-(피롤리딘-3-일)-7H-피롤로[2,3-d]피리미딘-4-아민 |
| GB201512733D0 (en) * | 2015-07-20 | 2015-08-26 | Genagon Therapeutics Ab | Therapeutic agents for treating conditions associated with elevated GDF15 |
| GB201700567D0 (en) | 2017-01-12 | 2017-03-01 | Genagon Therapeutics Ab | Therapeutic agents |
| ES2953017T3 (es) * | 2018-04-03 | 2023-11-07 | Sanofi Sa | Dispositivo de tira de inmunoensayo de flujo lateral |
| GB201808575D0 (en) | 2018-05-24 | 2018-07-11 | Galapagos Nv | Methods for the treatment of psoriatic arthrits |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| EP0786522A2 (en) | 1992-07-17 | 1997-07-30 | Ribozyme Pharmaceuticals, Inc. | Enzymatic RNA molecules for treatment of stenotic conditions |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| US20050043234A1 (en) * | 1996-10-16 | 2005-02-24 | Deisher Theresa A. | Novel FGF homologs |
| US6413776B1 (en) | 1998-06-12 | 2002-07-02 | Galapagos Geonomics N.V. | High throughput screening of gene function using adenoviral libraries for functional genomics applications |
| DE60016384T2 (de) | 1999-01-29 | 2005-12-01 | Chugai Seiyaku K.K. | Chondrogonese promotoren und indolin-2-on derivate |
| US6706267B1 (en) * | 1999-09-14 | 2004-03-16 | Arkion Life Sciences Llc | Glucosamine and egg for reducing inflammation |
| US7332337B2 (en) | 2000-05-16 | 2008-02-19 | Galapagos Nv | Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells |
| US20040053244A1 (en) * | 2000-05-18 | 2004-03-18 | Shyam Ramakrishnan | Regulation of human galanin receptor-like g protein coupled receptor |
| US7235233B2 (en) | 2000-09-26 | 2007-06-26 | Crucell Holland B.V. | Serotype 5 adenoviral vectors with chimeric fibers for gene delivery in skeletal muscle cells or myoblasts |
| WO2002070744A2 (en) | 2001-03-07 | 2002-09-12 | Galapagos Genomics B.V. | Adenoviral library assay for e2f regulatory genes and methods and compositions for screening compounds |
| EP1391211A1 (en) | 2001-04-27 | 2004-02-25 | Chugai Seiyaku Kabushiki Kaisha | Chondrogenesis promoters |
| US20030068779A1 (en) * | 2001-05-09 | 2003-04-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| ES2387546T3 (es) * | 2001-05-11 | 2012-09-25 | Amgen Inc. | Péptidos y moléculas relacionadas que se unen a TALL-1 |
| KR20020096368A (ko) * | 2001-06-19 | 2002-12-31 | 주식회사 티지 바이오텍 | 연골세포의 분화촉진, 연골세포의 탈분화 억제 또는탈분화된 연골세포의 재분화 촉진제, 그것의 스크리닝방법 및 그것을 이용한 연골세포의 제조방법 |
| EP1438402A2 (en) | 2001-08-22 | 2004-07-21 | Galapagos Genomics N.V. | Modulators of bone homeostasis identified in a high-throughput screen |
| US20030198627A1 (en) | 2001-09-01 | 2003-10-23 | Gert-Jan Arts | siRNA knockout assay method and constructs |
| WO2003072827A1 (en) * | 2001-10-31 | 2003-09-04 | Children's Hospital Medical Center | Method for diagnosis and treatment of rheumatoid arthritis |
| US20060046249A1 (en) * | 2002-01-18 | 2006-03-02 | Fei Huang | Identification of polynucleotides and polypetide for predicting activity of compounds that interact with protein tyrosine kinase and or protein tyrosine kinase pathways |
| JP2004000209A (ja) * | 2002-04-26 | 2004-01-08 | Sumitomo Pharmaceut Co Ltd | 軟骨障害マーカー及びその利用 |
| WO2004081563A2 (en) * | 2003-03-11 | 2004-09-23 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with phosphodiesterase 1a (pde1a) |
| AU2003224132A1 (en) | 2003-04-24 | 2004-11-19 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| WO2005063983A1 (en) * | 2003-12-29 | 2005-07-14 | Galapagos Genomics N.V. | Modulators of bone homeostasis identified in a high-throughput screen |
| JP2008503712A (ja) * | 2004-06-21 | 2008-02-07 | ガラパゴス・ナムローゼ・フェンノートシャップ | 骨関節炎治療の方法及び手段 |
-
2005
- 2005-06-21 JP JP2007515968A patent/JP2008503712A/ja active Pending
- 2005-06-21 EP EP11154007.6A patent/EP2360474B1/en not_active Expired - Lifetime
- 2005-06-21 EP EP05760933A patent/EP1759203A2/en not_active Withdrawn
- 2005-06-21 ES ES11154010T patent/ES2427136T3/es not_active Expired - Lifetime
- 2005-06-21 ES ES11154007T patent/ES2427046T3/es not_active Expired - Lifetime
- 2005-06-21 EP EP11154010.0A patent/EP2386856B1/en not_active Expired - Lifetime
- 2005-06-21 US US11/158,252 patent/US20070004658A1/en not_active Abandoned
- 2005-06-21 WO PCT/EP2005/052875 patent/WO2005124342A2/en not_active Ceased
-
2009
- 2009-10-07 US US12/575,220 patent/US20100087514A1/en not_active Abandoned
-
2011
- 2011-08-04 JP JP2011171363A patent/JP5595989B2/ja not_active Expired - Fee Related
- 2011-08-04 JP JP2011171061A patent/JP2012021995A/ja active Pending
-
2012
- 2012-01-27 US US13/360,393 patent/US8574857B2/en not_active Expired - Fee Related
-
2013
- 2013-10-17 US US14/055,955 patent/US20140107181A1/en not_active Abandoned
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