JP2008500376A - β−クリプトキサンチンの使用 - Google Patents
β−クリプトキサンチンの使用 Download PDFInfo
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- JP2008500376A JP2008500376A JP2007517026A JP2007517026A JP2008500376A JP 2008500376 A JP2008500376 A JP 2008500376A JP 2007517026 A JP2007517026 A JP 2007517026A JP 2007517026 A JP2007517026 A JP 2007517026A JP 2008500376 A JP2008500376 A JP 2008500376A
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- JP
- Japan
- Prior art keywords
- composition
- use according
- cryptoxanthin
- unhealthy
- protein production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
- 239000011647 vitamin D3 Substances 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 229940021056 vitamin d3 Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical class [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
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Abstract
Description
指定の成分(重量%)を含む小ビーズは、従来技術を用いて調製可能である。
以下のものを含有するように錠剤を製剤化する。
活性成分:
β−クリプトキサンチン 15mg
dl−アルファトコフェロール 300mg
賦形剤:
ラクトース粉末
サッカロース
マグネシウムステアレート
ゼラチン ad 500mg
以下の成分を含有するカプセル剤を調製する。
活性成分:
β−クリプトキサンチン 5mg
dl−アルファトコフェロール 100mg
賦形剤:
ゼラチン
ラクトース
マグネシウムステアレート
コメデンプン
グリセロールパルミトステアレート ad 300mg
以下の成分を用いて調製される乳児用調製乳は、100gあたり以下のものを含有しうる。
β−クリプトキサンチン 1mg
全脂肪 3.7g
ナトリウム 19mg
カリウム 76mg
全炭水化物 7.7g
タンパク質 1.5g
ビタミンおよびミネラル:
・ビタミンA 210IU
・ビタミンC 8.4mg
・ビタミンD 42IU
・ビタミンE 1.5IU
・ビタミンK 5.6μg
・チアミン(B1) 56.3μg
・リボフラビン(B2) 63.4μg
・ナイアシン(B3) 704.2μg
・ビタミンB6 42.2μg
・ホレート、葉酸、フォラシン 11.3μg
・ビタミンB12 0.2μg
・ビオチン 2.1μg
・パントテン酸 352.1mg
・カルシウム 54.9mg
・鉄 1.3mg
・リン 37.3mg
・ヨウ素 7μg
・マグネシウム 5.6mg
・亜鉛 0.7mg
・セレン 2μg
・銅 52.8μg
・マンガン 10.6μg
・クロライド 44.4mg
・カリウム 76mg
・コリン 8.4mg
・イノシトール 4.2mg
・リノール酸 605.6mg
・水 94.4g
250mlのエネルギー飲料は、以下のものを含有しうる。
β−クリプトキサンチン 5mg
タンパク質 3.9g
脂質 14.3g
炭水化物 71g
H2O ad 250ml
ビタミンおよびミネラル:
・ビタミンE 5mg
・ビタミンB1 1.2mg
・ビタミンB2 1.2mg
・ビタミンB6 1.2mg
・ビタミンC 45mg
・ナイアシン 9μg
・ナトリウム 190mg
・カリウム 180mg
・カルシウム 70mg
・リン 120mg
・マグネシウム 30mg
・鉄 1.3mg
・亜鉛 1.6mg
25gのエネルギーバーは、以下のものを含有しうる。
β−クリプトキサンチン 2.5mg
タンパク質 1g
脂質 3.5g
炭水化物 16.5g
繊維 3g
ビタミンおよびミネラル:
・ビタミンE 5mg
・ビタミンB1 1.2mg
・ビタミンB2 1.2mg
・ビタミンB6 1.2mg
・ビタミンC 45mg
・ナイアシン 11mg
・ナトリウム 190mg
・カリウム 180mg
・クロライド 210mg
・カルシウム 70mg
・リン 120mg
・マグネシウム 30mg
・鉄 1.3mg
・亜鉛 1.6mg
250mlのスポーツ飲料は、以下のものを含有する。
β−クリプトキサンチン 10mg
タンパク質 3.9g
脂質 14.3g
炭水化物 71g
H2O ad 250ml
ビタミンおよびミネラル:
・ビタミンE 5mg
・ビタミンB1 1.2mg
・ビタミンB2 1.2mg
・ビタミンB6 1.2mg
・ビタミンC 45mg
・ナイアシン 9mg
・ナトリウム 190mg
・カリウム 180mg
・カルシウム 70mg
・リン 120mg
・マグネシウム 30mg
・鉄 1.3mg
・亜鉛 1.6mg
家禽用の飼料予備混合物は、1kgあたり次のものを含有する。
ビタミンA(ロビミックス(Rovimix)(登録商標)A 500) 2g
ビタミンD3(ロビミックス(Rovimix)(登録商標)D3 500) 1g
ビタミンE(ロビミックス(Rovimix)(登録商標)E 50 Ads) 4g
ビタミンB12(B12 1%) 0.1g
ビタミンB3(ロビミックス(Rovimix)(登録商標)B2 80−SD) 0.5g
ナイアシン(ロビミックス(Rovimix)(登録商標)ナイアシン) 0.1g
カルパン(Calpan)(ロビミックス(Rovimix)(登録商標)カルパン(Calpan)) 0.05g
葉酸(ロビミックス(Rovimix)(登録商標)フォリック(Folic)80 SD) 2mg
ビタミンB6(ロビミックス(Rovimix)(登録商標)B6) 8mg
ビタミンB1(ロビミックス(Rovimix)(登録商標)B1) 4mg
ビタミンC 0.2g
カロテノイド(カロフィル(Carophyll)(登録商標)レッド) 2g
β−クリプトキサンチン小ビーズ配合物 5% 2g
(実施例1参照)
コリンクロライド 50% 150g
Mn(IV)酸化物 30g
Zn酸化物 6g
Fe(II)硫酸塩一水和物 10g
Cu(II)酸化物 1g
Co(II)硫酸塩 0.1g
担体
(石灰石、モミガラ、コムギミドリング) 792g
全量 1000g
Claims (29)
- ヒトまたは動物においてタンパク質生成の増大および/またはタンパク質損失の防止を促進するための組成物の製造におけるβ−クリプトキサンチンの使用。
- 前記組成物が、不健康状態に基づいてタンパク質生成の増大および/またはタンパク質の損失の防止を促進するためのものである、請求項1に記載の使用。
- 前記不健康状態が、慢性疾患、腫瘍悪液質、または摂食障害である、請求項2に記載の使用。
- 前記不健康状態がウイルス感染症である、請求項2に記載の使用。
- 前記不健康状態が、第二度もしくは第三度の火傷の後、心筋梗塞の後、または臓器移植の後の状態である、請求項2に記載の使用。
- 前記不健康状態が骨格損傷または手術の後の不動化状態である、請求項2に記載の使用。
- 前記組成物が、成長および発達を促進するためのものである、請求項1に記載の使用。
- 前記組成物が、スポーツおよびトレーニング活動においてタンパク質生成の増大を促進するためのものである、請求項1に記載の使用。
- 前記組成物が、老化期においてタンパク質生成の増大および/または防止ならびに筋減少症の治療を促進するためのものである、請求項1に記載の使用。
- 前記組成物が、家畜およびペットにおいて成長を促進するためのものならびに競技動物の能力を向上させるためのものである、請求項1に記載の使用。
- 前記組成物が生薬組成物である、請求項1〜10のいずれか一項に記載の使用。
- 前記組成物が食物組成物である、請求項1〜10のいずれか一項に記載の使用。
- 前記食物組成物が飼料または飼料予備混合物である、請求項12に記載の使用。
- 前記β−クリプトキサンチンがall−Eβ−クリプトキサンチンである、請求項1〜13のいずれか一項に記載の使用。
- 前記組成物中のβ−クリプトキサンチンの量が、固体組成物の投与ユニット1つあたり約50mgまでおよび液体組成物1mlあたり約50μgまでである、請求項11に記載の使用。
- 前記組成物中のβ−クリプトキサンチンの量が全組成物1gあたり約5mgまでである、請求項12に記載の使用。
- 前記組成物がビタミンEおよびビタミンCの少なくとも1種を追加的に含有する、請求項1〜16のいずれか一項に記載の使用。
- ヒトまたは動物においてタンパク質生成の増大および/またはタンパク質損失の防止を促進する方法であって、前記ヒトまたは動物に有効量のβ−クリプトキサンチンを投与することを含む、方法。
- 不健康状態を改善するための、請求項18に記載の方法。
- 前記不健康状態が、慢性疾患、腫瘍悪液質、または摂食障害である、請求項19に記載の方法。
- 前記不健康状態がウイルス感染症である、請求項19に記載の方法。
- 前記不健康状態が、第二度もしくは第三度の火傷の後、心筋梗塞の後、または臓器移植の後の状態である、請求項19に記載の方法。
- 前記不健康状態が骨格損傷または手術の後の不動化状態である、請求項19に記載の使用。
- 前記タンパク質生成の増大が、成長および発達を促進するためのものである、請求項18に記載の方法。
- スポーツおよびトレーニング活動においてタンパク質生成の増大を促進するための、請求項18に記載の方法。
- 老化期においてタンパク質生成の増大および/またはタンパク質損失の防止を促進するための、請求項18に記載の方法。
- 前記タンパク質生成の増大が、家畜およびペットの成長を促進するためのものならびに競技動物の能力を向上させるためのものである、請求項18に記載の方法。
- 約50mgまで、より特定的には約100μg/日〜約30mg/日、とくに約1mg/日〜約10mg/日のβ−クリプトキサンチンが、約70kgの体重のヒト成人に投与される、請求項18〜27のいずれか一項に記載の方法。
- 胆汁酸塩または利胆刺激剤が共投与される、請求項18〜28のいずれか一項に記載の方法。
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PCT/EP2005/005030 WO2005110122A1 (en) | 2004-05-18 | 2005-05-10 | USE OF β-CRYPTOXANTHIN |
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JP2011116735A (ja) * | 2009-09-25 | 2011-06-16 | Ehime Univ | 免疫蛋白質の産生促進剤 |
JP2012139212A (ja) * | 2010-12-15 | 2012-07-26 | Arkray Inc | 安定化βクリプトキサンチン含有水およびその用途 |
JP2018503372A (ja) * | 2015-01-15 | 2018-02-08 | ディーエスエム アイピー アセッツ ビー.ブイ. | 家禽における肥満及び心血管障害を予防する方法 |
JP2019218316A (ja) * | 2018-06-21 | 2019-12-26 | 公立大学法人大阪 | オートファジー活性向上剤 |
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WO2008013219A1 (en) * | 2006-07-28 | 2008-01-31 | Unitika Ltd. | Oral composition enabling increased absorption of cryptoxanthin |
US20090118227A1 (en) | 2007-11-07 | 2009-05-07 | Bristol-Myers Squibb Company | Carotenoid-containing compositions and methods |
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- 2005-05-10 US US11/596,618 patent/US20080070980A1/en not_active Abandoned
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JP2011116735A (ja) * | 2009-09-25 | 2011-06-16 | Ehime Univ | 免疫蛋白質の産生促進剤 |
JP2012139212A (ja) * | 2010-12-15 | 2012-07-26 | Arkray Inc | 安定化βクリプトキサンチン含有水およびその用途 |
JP2018503372A (ja) * | 2015-01-15 | 2018-02-08 | ディーエスエム アイピー アセッツ ビー.ブイ. | 家禽における肥満及び心血管障害を予防する方法 |
JP2018503628A (ja) * | 2015-01-15 | 2018-02-08 | ディーエスエム アイピー アセッツ ビー.ブイ. | ウシの健康のための、25−ヒドロキシビタミンdおよび抗酸化剤/抗炎症剤の組合せ |
JP2018504106A (ja) * | 2015-01-15 | 2018-02-15 | ディーエスエム アイピー アセッツ ビー.ブイ. | 25−ヒドロキシビタミンdと酸化防止剤/抗炎症剤との組み合わせを含む家禽飼料 |
JP2018506962A (ja) * | 2015-01-15 | 2018-03-15 | ディーエスエム アイピー アセッツ ビー.ブイ. | 家禽の卵巣の健康のための25−ヒドロキシビタミンdと酸化防止剤/抗炎症剤との組み合わせ |
JP2019218316A (ja) * | 2018-06-21 | 2019-12-26 | 公立大学法人大阪 | オートファジー活性向上剤 |
Also Published As
Publication number | Publication date |
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DE602005024128D1 (de) | 2010-11-25 |
KR101317976B1 (ko) | 2013-10-14 |
JP5145035B2 (ja) | 2013-02-13 |
EP1748705B1 (en) | 2010-10-13 |
EP1748705A1 (en) | 2007-02-07 |
ES2351701T3 (es) | 2011-02-09 |
WO2005110122A1 (en) | 2005-11-24 |
JP2013047227A (ja) | 2013-03-07 |
CN1953669A (zh) | 2007-04-25 |
CN1953669B (zh) | 2010-06-16 |
US20080070980A1 (en) | 2008-03-20 |
KR20070011515A (ko) | 2007-01-24 |
ATE484201T1 (de) | 2010-10-15 |
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